Head and Neck Cancer: Present Status and Future Prospects of Adjuvant Chemotherapy

References

• Fletcher G H, Jesse R H. The place of irradiation in the management of the primary lesion in the head and neck cancer. Cancer 1977; 39: 862–867
   PubMed Web of Science ®Google Scholar
• Fazekas J T, Sommer C, Kramer S. Adjuvant intravenous meth-otrexate or definitive radiotherapy alone for advanced squamous cancers of the oral cavity, oropharynx, supraglottic larynx or hypopharynx. Int J Radiat Oncol Biol Phys 1980; 6: 533–541
   PubMed Web of Science ®Google Scholar
• Fazekos J T, Sommer C, Kramer S. Tumor regression and other progisticators in advanced head and neck cancers. Int J Radiat Oncol Biol Phys 1983; 9: 957–959
   PubMed Web of Science ®Google Scholar
• Hintz B, Chayulu K, Chandler J R. Randomized study of control of the primary tumor and surviving using pre-operative radiation, radiation alone or surgery alone in head and neck carcinomas. J Surg Oncol 1979; 12: 75–85
   PubMed Web of Science ®Google Scholar
• Kramer S, Gelber R D, Snow J B. Pre-operative vs. post-operative radiation therapy for patients with carcinoma of the head and neck. Progress report. Head Neck Surg 1985; 3: 255
   Google Scholar
• Schuller D E, McGuirt W F, Krause C J. Symposium: Adjuvant cancer therapy of head and neck tumors. Increased survival with surgery alone vs. combined therapy. Laryngoscope 1979; 89: 582–594
   PubMed Web of Science ®Google Scholar
• Adjuvant chemotherapy for advanced head and neck squamous carcinoma. Final report of the Head and Neck Contract Program. Cancer 1987; 60: 301–311
   PubMed Web of Science ®Google Scholar
• Cachin Y, Eschwage F. Combination of radiotherapy and surgery in the treatment of head and neck cancer. Cancer Treat Rev 1975; 2: 177–191
   PubMed Web of Science ®Google Scholar
• Papal J R. Distant metastases from head and neck cancer. Cancer 1984; 53: 342–345
   PubMed Web of Science ®Google Scholar
• Vikram B, Strong E W, Shah J P. Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg 1984; 6: 720–723
   PubMedGoogle Scholar
• Vikram B, Strong E W, Shah J P. Failure in thc neck following multimodality treatment for advanced head and neck cancer. Head Neck Surg 1984; 6: 724–729
   PubMedGoogle Scholar
• Vikram B, Strong E W, Shah J P. Failure at distant sites following multimodality treatment for advanced head and neck cancer. Head Neck Surg 1984; 6: 73–733
   Google Scholar
• Ellis E R, Mendenhall W M, Rao P V. Does node location affect the incidence of distant metastases in head and neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys 1989; 17: 293–297
   PubMed Web of Science ®Google Scholar
• Al-Sarraf M. Chemotherapeutic management of head and neck cancer. Cancer Metast Rev 1987; 6: 181–198
   PubMed Web of Science ®Google Scholar
• Al-Sarraf M. Chemotherapy strategies in squamous cell carcinonia of the head and neck. CRC Crit Rev Oncol/Hematol 1984; 1: 323–155
   PubMed Web of Science ®Google Scholar
• Al-Sarraf M. Head and neck cancer: Chemotherapy concepts. Semin Oncol 1988; 15: 70–85
   PubMed Web of Science ®Google Scholar
• Tarpley J L, Chretien PB., Alexander J C. High dose methotrexate as a preoperative adjuvant in the treatment of epidermoid carcinoma of the head and neck: A feasibility study and clinical trial. Am J Surg 1975; 130: 147
   Google Scholar
• Wittes R, Heller K, Randolph V. Cis-dichlorodiam-mineplatinum (II) based chemotherapy in initial treatment of advanced head and neck cancer. Cancer Treat Rep 1979; 63: 1533–1538
   PubMedGoogle Scholar
• Schuller D E, Metch B, Stein D W. Preoperative chemotherapy in advanced resectable head and neck cancer: Final report of the Southwest Oncology Group. Laryngoscope 1988; 98: 1205–1211
   PubMed Web of Science ®Google Scholar
• Al-Samf M, Drelichman A, Peppard S. Adjuvant cis-plat-inum and 5-fluorouracil 96 hours infusion in previously untreated epidermoid cancers of the head and neck. Proc AACR-ASCO 1981; 22: 428
   Google Scholar
• Kish J, Drelichman A, Jacobs J. Clinical trial of cis-platinum and 5-FU infusion as initial treatment for advanced squamous carcinoma of the head and neck. Cancer Treat Rep 1982; 66: 471–474
   PubMedGoogle Scholar
• Al-Kourainy K, Kish J, Ensley J. Achievement of superior survival for histologically negative vs. histologically positive clinically complete responders to cis-platinum combination in patients with locally advanced head and neck cancer. Cancer 1987; 59: 233–238
   PubMed Web of Science ®Google Scholar
• Vokes E E, Choi K E, Schilsky R L. Cisplatin, fluorouracil. and high-dose leucovorin for recurrent or metastatic head and neck cancer. J Clin Oncol 1988; 6: 618–626
   PubMed Web of Science ®Google Scholar
• Al Dreyfuss, Clark J R, Wright J E. Continuous infusion high-dose leucovorin with 5-fluorouracil and cisplatin for untreated stage IV carcinoma of the head and neck. Ann Intern Med 1990; 112: 167–172
   PubMed Web of Science ®Google Scholar
• Ensley J F, Jacobs J R, Weaver A. The correlation between response to cis-platinum combination chemotherapy and subsequent radiotherapy in previously untreated patients with advanced squamous cell cancers of the head and neck. Cancer 1984; 54: 811–814
   PubMed Web of Science ®Google Scholar
• Jacobs C, Goffinet D R, Goffinet L. Chemotherapy as a substitute for surgery in the treatment of advanced resectable head and neck cancer. Cancer 1987; 60: 1178–1183
   PubMed Web of Science ®Google Scholar
• Hong W K, O'Donoghue G M, Sheetz S. Sequential response patterns to chemotherapy and radiotherapy in head and neck cancer: Potential impact of treatment in advanced laryngeal cancer. Primary Chemotherzpy in Cancer Medicine, DJT Wagener, GH Blijham, JBE Smeets, JA Wils. Alan R Liss, New York 1985; 191–197
   Google Scholar
• Panis Coninx X. P., Nguyen T D, Legros M. Relation between responses to induction chemotherapy and subsequent radiotherapy in advanced or niulticentnc squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys 1990; 18: 1315–1318
   PubMed Web of Science ®Google Scholar
• Click J H, Marcial Richter V. M., Velez-Garcia E. The adjuvant treatment of inoperable stage III and IV epidermoid carcinoma of the head and neck witb platinum and bleomycin infusions prior to definitive radiotherapy. Cancer 1980; 46: 1919–1924
   PubMed Web of Science ®Google Scholar
• Ensley Ahmad J. K., Kish J. Improved response to radiation and concurrent cisplatinum (CACP) in patients with advanced head and neck cancers (SCCHN) that fail induction chemotherapy. Proc ASCO 1989; 8: 168
   Google Scholar
• Al-Sarraf Kinrie M. J., Jacobs J. A new way of giving chemotherapy as part of multi-disciplinary treatment for patients with head and neck cancers. Preliminary report. Proc AACR 1982; 23: 134
   Google Scholar
• Al-Sarraf M, Pajack T, Laramore G. Timing of chemotherapy as part of definitive treatment for patients with advanced head and neck cancer. An RTOG study. Proc ASCO 1985; 4: 141
   Google Scholar
• Al-Sarraf M. Timing of chemotherapy as part of multimodality treatment in patients with advanced head and neck cancer. Cancers of Head and Neck, C Jacobs. Martinus Nijhoff Publ. 1987; 143–154
   Google Scholar
• Jacobs J R, Fu K K, Lowry L D. Five-year results of cisplatinum and 5-fluorouracil chemotherapy in the treatment of advanced resectable head and neck carcinoma—RTOG report. Arch Otolaryngol Head Neck Surg 1991; 117: 288–291
   PubMedGoogle Scholar
• Laramore GE., Scott C B, Al-Sarraf M. Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: Report on Intergroup Study 0034. Int J Radiat Oncol Biol Phys 1991; 21: 190, (Suppl. 1)
   Google Scholar
• Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991; 325: 1685–1690
   Google Scholar
• Al-Sarraf M, Kish J A, Ensley J F. Head and neck cancer: The Wayne State University experience with adjuvant chemotherapy. Hematol/Oncol Clin North Am 1991; 5: 687–700
   PubMed Web of Science ®Google Scholar
• Banchard J M, David J, Boussin M. G., Daly N. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: Preliminary report of a randomized trial. Int J Radiat Oncol Biol Phys 1991; 243–246
   Web of Science ®Google Scholar
• Ervin T J, Clark J R, Weichselbaun R R. An Analysis of induction and adjuvant chemotherapy in the multidisciplinary treatment of squamous cell carcinoma of the head and neck. J Clin Oncol 1987; 5: 10–20
   PubMed Web of Science ®Google Scholar
• Pfister D G, Strong E, Harrison L. Larynx preservation with combined chemotherapy and radiation therapy in advanced but resectable head and neck cancer. J Clin Oncol 1991; 9: 850–859
   PubMed Web of Science ®Google Scholar
• Demard F, Chauvel P, Santini J. Response to chemotherapy as justification for modification of the therapeutic strategy for pharyngolaryngeal carcinomas. Head Neck 1990; 12: 225–231
   PubMed Web of Science ®Google Scholar
• Karp D, Carter R, Vaughn C. Voice preservation using induction chemotherapy (CT) plus radiation therapy (RT) as an alternative to laryngectomy in advanced head and neck cancer: Long term followup. Proc ASCO 1988; 7: 152
   Google Scholar
• Vikram B, Bosl G J, Pfister D. New strategy for avoiding total laryngectomy in patients with head and neck cancer. NCI Monogr 1988; 6: 361–364
   PubMedGoogle Scholar
• Douple E B, Richmond R C, Logan M E. Therapeutic population in a mouse tumor and an intracerebral rat brain tumor by combined treatment with cisdichlorodiamminneplatinum (II) and radiation. J Clin Hematol Oncol 1977; 7: 585–603
   Google Scholar
• Dewit L. Combined treatment with radiation and cisdiam-minedicholoroplatinum (II): A review of experimental and clinical data. Int J Radiat Oncol Biol Phys 1987; 13: 403–426
   PubMed Web of Science ®Google Scholar
• Al-Sarraf M, Pajak T, Marcial V A. Concurrent radiotherapy and chemotherapy with cisplatin in inoperable squamous cell carcinoma of the head and neck. RTOG study. Cancer 1987; 59: 259–265
   PubMed Web of Science ®Google Scholar
• Haselow R E, Warshaw M G, Oken M M. Radiation alone versus radiation with weekly low dose cis-platinum in unresect-able cancer of the head and neck. Head and Neck Cancer, vol 2, WE Fee, Jr, H Goepfert, ME Johns. PA Decker, Philadelphia 1990; 270–281
   Google Scholar
• Vokes E E, Weichselbaum R R. Concomitant chemoradiotherapy and clinical experience in patients with solid tumors. J Clin Oncol 1990; 8: 911–934
   PubMed Web of Science ®Google Scholar
• Harrison L B, Pfister D G, Fass D E. Concomitant chemotherapy-radiation therapy followed by hyperfractionated radiation therapy for advanced unresectable head and neck cancer. Int J Radiat Oncol Biol Phys 1991; 21: 703–708
   PubMed Web of Science ®Google Scholar
• Marcial V A, Pajak T F, Mohiuddin M. Concomitant cis-platin chemotherapy and radiotherapy in advanced mucosal squamous cell carcinoma of the head and neck: Longterm results of the Radiation Therapy Oncology Group Study 81–17. Cancer 1990; 66: 1861–1868
   PubMed Web of Science ®Google Scholar
• Al-Sarraf Pajak M. T., Jacobs J. Combined modality therapy (CMT) in patients with head and neck (HN-CA): Timing of chemotherapy (CT). Radiation Therapy Oncology Group (RTOG) Study. Adjuvant Therapy of Cancer VI, S Salmon. WB Saunders, Philadelphia 1990; 60–70
   Google Scholar
• Edelstein D J, Sharan V M, Earle A S. Simultaneous versus sequential combined technique therapy for squamous cell head and neck cancer. Cancer 1990; 65: 1685–1691
   PubMed Web of Science ®Google Scholar
• Taylor SG, IV, Murthy AK., Caldarelli D D. Combined simultaneous cisplatinifluorouracil chemotherapy and split course radiation in head and neck cancer. J Clin Oncol 1989; 7: 846–856
   PubMed Web of Science ®Google Scholar
• Vokes E E, Panje W R, Schilsky R L. Hydroxyurea, fluorouracil, and concomitant radiotherapy in poor-prognosis head and neck cancer: A phase I–II study. J Clin Oncol 1989; 7: 761–768
   PubMed Web of Science ®Google Scholar
• Merlano Vitale M. V., Rosso R. Treatment of advanced squamous cell carcinoma of the head and neck with alternating chemotherapy and radiotherapy. N Engl J Med 1992; 327: 1115–1121
   PubMed Web of Science ®Google Scholar
• Cognetti F, Pinnaro P, Carlini P. Neoadjuvant chemotherapy in previously untreated patients with advanced head and neck squamous cell cancer. Cancer 1988; 62: 251–261
   PubMed Web of Science ®Google Scholar
• Spaulding M B, Lore J M, Sundquist N. Long-term follow-up of chemotherapy in advanced head and neck cancer. Arch Oto-laryngol Head Neck Surg 1989; 115: 68–73
   PubMed Web of Science ®Google Scholar
• Flores A D, Dickson R I, Riding K. Cancer of the nasopharynx in British Columbia. Am J Clin Oncol 1986; 9: 281–291
   PubMed Web of Science ®Google Scholar
• Qin D, Hu Y, Yan J. Analysis of 1379 patients with nasopharyngeal carcinoma treated by radiation. Cancer 1988; 61: 1117–1124
   PubMed Web of Science ®Google Scholar
• Decker D, Drielchman A, Al-Sarraf M. Chemotherapy for nasopharyngeal carcinoma: A 10-year experience. Cancer 1983; 52: 602–605
   PubMed Web of Science ®Google Scholar
• Al-Kourainy K, Crissman J, Ensley J F. Excellent response to cisplatinum based chemotherapy in patients with recurrent or previously untreated advanced nasopharyngeal carcinoma. Am J Clin Oncol (CCT) 1988; 11: 427–430
   PubMed Web of Science ®Google Scholar
• Al-Sarraf M, Pajak T F, Cooper J S. Chemo-radiotherapy in patients with locally advanced nasopharyngeal carcinoma. A Radiation Oncology Group Study. J Clin Oncol 1990; 8: 1342–1351
   PubMed Web of Science ®Google Scholar
• Tannock I, Payne D, Cummings B. Sequential chemotherapy and radiation for nasopharyngeal cancer: Absence of long-term benefit despite a high rate of tumor response to chemotherapy. J Clin Oncol 1987; 6: 629–634
   Google Scholar
• Rossi A, Molinari R, Borracchi P. Adjuvant chemotherapy with vincristine, cyclopbosphamide and doxorubicin after radiotherapy in locol-regional nasopharyngeal cancer: Results of a four year multicenter randomized trial. J Clin Oncol 1988; 6: 1401–1410
   PubMed Web of Science ®Google Scholar
• Atichartakarn V, Kraiphibul P., Clongsusuek P. Nasopharyngeal carcinoma: Result of treatment with cis-diammine-dichloroplatinum II, 5 fluorouracil, and radiation therapy. Int J Radiat Oncol Biol Phys 1988; 14: 461–469
   PubMed Web of Science ®Google Scholar
• Fu K K, Phillips T L, Silverberg I J. Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: Update of a Northern California Oncology Group randomized trial. J Clin Oncol 1987; 5: 1410–1418
   PubMed Web of Science ®Google Scholar
• Weissberg J B, Son Y H, Papac R J. Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer. Int J Radiat Oncol Biol Phys 1989; 17: 3–9
   PubMed Web of Science ®Google Scholar
• Vermund H, Kaalhus O, Winther F. Bleomycin and radiation therapy in squamous cell carcinoma of the upper aero-digestive tract: A phase III clinical trial. Int J Radiat Oncol Biol Phys 1985; 11: 1877–1886
   PubMed Web of Science ®Google Scholar
• Cachin Y, Jortay A, Eschwege F. Preliminary results of a randomized EORTC study comparing radiotherapy and concomitant bleomycin to radiotherapy alone in epidermoid carcinomas of the oropharynx. Eur J Cancer 1977; 13: 1389–1395
   PubMed Web of Science ®Google Scholar
• Kapstad B, Bang G, Rennaes S, Dahler A. Combined preoperative treatment with cobalt and bleomycin in patients with head and neck carcinoma—A controlled clinical study. Int J Radiat Oncol Biol Phys 1978; 4: 85–89
   PubMed Web of Science ®Google Scholar
• Shanta V, Krishnamurthi S. Combined bleomycin and radiotherapy in oral cancer. Clin Radiol 1980; 31: 617–620
   PubMed Web of Science ®Google Scholar
• Morita K. Clinical significance of radiation therapy combined with chemotherapy. Strablentherapie 1980; 156: 228–233
   PubMedGoogle Scholar
• Shigenatsu Y, Sakai S, Fuchihata H. Recent trials in the treatment of maxillary sinus carcinoma, with special reference to the chemical potentiation of radiation therapy. Acta Otalaryngol 1971; 71: 63–70
   PubMed Web of Science ®Google Scholar
• Lo T MC, Wiley A I, Ansfield F J. Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oval cavity and oropharynx: A randomized study. Am J Roentgenol 1976; 126: 229–235
   PubMed Web of Science ®Google Scholar
• Richards G J, Chambers R G. Hydroxyurea: A radiosensitizer in the treatment of neoplasms of the head and neck. Am J Roentgenol 1969; 105: 555–565
   Web of Science ®Google Scholar
• Stefani S, Eelles R W, Abbate J. Hydroxyurea and radiotherapy in head and neck cancer. Radiology 1971; 101: 391–396
   PubMed Web of Science ®Google Scholar
• Hussey DH., Abrams J P. Combined therapy in advanced head and neck cancer: Hydroxyurea and radiotherapy. Prog Clin Cancer 1975; 6: 79–86
   PubMedGoogle Scholar
• Merlano M, Corvo R, Margarino G. Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial. Cancer 1991; 67: 915–921
   PubMed Web of Science ®Google Scholar
• Martin M, Hazan A, Vergnes L. Randomized study of 5 fluorouracil and cis-platin as neoadjuvant therapy in head and neck cancer: A preliminary report. Int J Radiat Oncol Biol Phys 1990; 19: 973–975
   PubMed Web of Science ®Google Scholar
• Volling P, Schroder M, Rauschning W. Carboplatin. The better platinum in head and neck cancer. Arch Otolaryngol Head Neck Surg 1989; 115: 695–698
   PubMed Web of Science ®Google Scholar
• Statistical Methods for Rates and Proportions, 2nd ed, J L Fleiss. Wiley, New York 1981; 24–25
   Google Scholar
• Lachin J M. Introduction to sample size determination and power analysis for clinical trials. Controlled Clin Trials 1981; 2: 93–113
   PubMedGoogle Scholar
• The Design and Analysis of Clinical Experiments, J L Fleiss. Wiley, New York 1986
   Google Scholar