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Cancer Investigation Volume 16, 1998 - Issue 2
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Original Article

Lack of Increased Cardiac Toxicity with Sequential Doxorubicin and Paclitaxel

Clifford Hudis Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Louise Riccio Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Andrew Seidman Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Jose Baselga Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Violante Currie Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
David Fennelly Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Teresa Gilewski Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
David Lebwohl Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Maryellen Moynahan Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
George Raptis Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Antonella Surbone Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Nancy Sklarin Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
T. J. Yao Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
,
Deborah Keefe Cardiology Service, Division of General Medicine Department of Medicine, Memorial Sloan-Kettering Cancer Center New York, New York
&
Larry Norton Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York; Breast and Gynecologic Cancer Medicine Service Division of Solid Tumor Oncology Department of Medicine, Cornell University Medical College, New York
 show all
Pages 67-71 | Published online: 11 Jun 2009

References

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  • Reichman B S, Seidman A D, Crown J P, et al. Paclitaxel and recombinant human granulocyte colony-stimulating factor as ini tial chemotherapy for metastatic breast cancer. J Clin Oncol 1993; 10: 1943–1951
  • Fisherman J S, McCabe M, Noone M, et al. Phase I study of Taxol, doxorubicin, plus granulocyte colony-stimulating factor in patients with metastatic breast cancer. Monogr Natl Cancer Inst 1993; 15: 189–194
  • Buzdar A M, Holmes F A, Hortobagyi G N. Paclitaxel in the treatment of metastatic breast cancer: M.D. Anderson Cancer Center experience. Semin Oncol 1995; 22(3 Suppl 6)101–104
  • Sledge G W, Goldstein R N, Sparano J, et al. Phase I trial of Adriamycin and Taxol in metastatic breast cancer. Proc Eur Conf Clin Oncol 1993; 7: A421, (abstract)
  • Gianni L, Munzone E, Capri G., et al. Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study. J Clin Oncol 1995; 13: 2688–2699
  • Dombemowsky P., Gehl J, Ejlersen B, Boesgaard M. Treatment of metastatic cancer with paclitaxel and doxorubicin. Emerging Strategies in Medical Oncology. European Society for Medical Oncology. 19th Congress, LisbonPortugal, Nov, 18–221994, 5–6
  • Hudis C, Seidman A, Baselga J, et al. Sequential adjuvant therapy with doxorubicin/paclitaxel/cyclophosphamide for resectable breast cancer involving four or more axillary nodes. Semin Oncol 1995; 22(4 Suppl L)1–6
  • Allen A. The cardiotoxicity of chemotherapeutic drugs. Semin Oncol 1992; 5: 529–542
  • VonHoff D D, Layard M W, Basa P, et al. Risk factors for doxorubicin-induced congestive heart failure. Ann Intern Med 1979; 91: 710–717
  • Rowinsky E, Donehower R. Paclitaxel (Taxol). N Engl J Med 1995; 15: 1004–1014

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