References
- Benedetti A, Daly S, Xaiz R, Pagani H. (2009). A process for the preparation of vitamin K2. European Patent 20070154998
- Bentley R, Meganathan R. (1982). Biosynthesis of vitamin K (menaquinone) in bacteria. Microbiol Rev, 46, 241–80
- Berenjian A, Mahanama R, Talbot A, et al. (2011). Efficient media for high menaquinone-7 production: response surface methodology approach. N Biotechnol, 28, 665–72
- Berenjian A, Mahanama R, Talbot A, et al. (2012). Advances in menaquinone-7 production by Bacillus subtilis natto: fed-batch glycerol addition. Am J Biochem Biotechnol, 8, 105–10
- Berenjian A, Chan NLC, Mahanama R, et al. (2013). Effect of Biofilm Formation by Bacillus subtilis natto on Menaquinone-7 Biosynthesis. Mol Biotechnol, 54, 371–8
- Beulens JW, Bots ML, Atsma F, et al. (2009). High dietary menaquinone intake is associated with reduced coronary calcification. Atherosclerosis, 203, 489–93
- Binkley SB, MacCorquodale DW, Thayer SA, Doisy EA. (1978). The isolation of vitamin K 1. Nutr Rev, 36, 302–4
- Blume SW, Curtis JR. (2011). Medical costs of osteoporosis in the elderly Medicare population. Osteoporos Int, 22, 1835–44
- Booth SL. (2009). Roles for vitamin K beyond coagulation. Annu Rev Nutr, 29, 89–110
- Booth SL, Dallal G, Shea MK, et al. (2008). Effect of vitamin K supplementation on bone loss in elderly men and women. J Clin Endocrinol Metab, 93, 1217–23
- Braam LA, Knapen MH, Geusens P, et al. (2003). Vitamin K1 supplementation retards bone loss in postmenopausal women between 50 and 60 years of age. Calcif Tissue Int, 73, 21–6
- Branda SS, Vik S, Friedman L, Kolter R. (2005). Biofilms: the matrix revisited. Trends Microbiol, 13, 20–6
- Brodie AF, Ballantine J. (1960a). Oxidative phosphorylation in fractional bacterial systems. III. Specificity of vitamin K reactivation. J Bioi Chem, 235, 232–7
- Brodie AF, Ballantine J. (1960b). Phosphorylation in fractionated bacterial systems II. The role of vitamin K. J Biol Chem, 235, 226–31
- Chen KI, Erh MH, Su NW, et al. (2012). Soyfoods and soybean products: from traditional use to modern applications. Appl Microbiol Biotechnol, 96, 9–22
- Cheung AM, Tile L, Lee Y, et al. (2008). Vitamin K supplementation in postmenopausal women with osteopenia (ECKO Trial): a randomized controlled trial. PLoS Med, 5, 1461–72
- Christodoulou C, Cooper C. (2003). What is osteoporosis? Postgrad Med J, 79, 133–8
- Cockayne S, Adamson J, Lanham-New S, et al. (2006). Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med, 166, 1256–61
- Commercial Insight: Osteoporosis. (2009). Market players maximize revenue growth before the next challenging phase. Available form: http://www.researchandmarkets.com/reports/1382750/commercial_insight_osteoporosis_market_players
- Dahlöf B. (2010). Cardiovascular disease risk factors: epidemiology and risk assessment. Am J Cardiol, 105, 3A–9A
- Dam H. (1935). The antihaemorrhagic vitamin of the chick: occurrence and chemical nature. Nature, 135, 652–3
- Dam H, Geiger A, Glavind J, et al. (1939). Isolierung des vitamins K in hochgereinigter form. Helv Chim Acta, 22, 310–3
- Dam H. (1966). Historical survey and introduction. Vitam Horm, 24, 295–306
- Daniells S. (2010). US Vitamin K market set for explosion? Available from: http://www.nutraingredients-usa.com/Industry/US-Vitamin-K-market-set-for-explosion
- Dehghani F, Kavanagh J, Talbot A, et al. (2013). Fermentation and in-situ extraction of Menaquinone-7. Australian Patent 2013900664
- Eisai. (2010). Available from: http://www.eisai.com/pdf/eir/erepo/epdf2010q4.pdf
- Emaus N, Gjesdal CG, Almås B, et al. (2010). Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomized double-blind placebo-controlled trial. Osteoporos Int, 21, 1731–40
- European Safety. (2008). Scientific Opinion of the Panel on Dietetic Products Nutrition and Allergies on a request from the European Commission on the safety of ‘Vitamin K2’. EFSA J, 822, 1–32. Available from: http://www.efsa.eu.int/science/nda/nda_opinions/catindex_en.html
- Farrand S. Taber H. (1974). Changes in menaquinone concentration during growth and early sporulation in Bacillus subtilis. J Bacteriol, 117, 324–6
- Ferland G. (1998). The vitamin K-dependent proteins: an update. Nutr Rev, 56, 223–30
- Ferland G. (2012). The discovery of vitamin K and its clinical applications. Ann Nutr Metab, 61, 213–8
- Feskanich D, Weber P, Willett WC, et al. (1999). Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr, 69, 74–9
- Gast GC, de Roos NM, Sluijs I, et al. (2009). A high menaquinone intake reduces the incidence of coronary heart disease. Nutr Metab Cardiovas, 19, 504–10
- GCDM. (2010). Global Cardiovascular Drugs Market to Exceed $111.8 Billion by 2015, According to a New Report by Global Industry Analysts, Inc. Available from: http://www.prweb.com/releases/cardiovascular_drugs/antihyperlipidemics/prweb3729014.htm
- Geleijnse JM, Vermeer C, Grobbee DE, et al. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam study. J Nutr, 134, 3100–5
- Gundberg CM, Lian JB, Booth SL. (2012). Vitamin K-dependent carboxylation of osteocalcin: friend or foe? Adv Nutr, 3, 149--157
- Haroon Y, Bacon DS, Sadowski JA. (1986). Liquid-chromatographic determination of vitamin K1 in plasma, with fluorometric detection. Clin Chem, 32, 1925–9
- Hirauchi K, Sakano T, Notsumoto S, et al. (1989a). Measurement of K vitamins in animal tissues by high-performance liquid chromatography with fluorimetric detection. J Chromatogr, 497, 131–7
- Hodges SJ, Bejui J, Leclercq M, Delmas PD. (1993). Detection and measurement of vitamins K1 and K2 in human cortical and trabecular bone. J Bone Miner Res, 8, 1005–8
- Howard LM, Payne AC. (2006). Health benefits of vitamin K2: a revolutionary natural treatment for heart disease and bone loss. Laguna Beach, CA: Basic Health Publications
- IARC. (2000). Monographs on the evaluation of carcinogenic risks to humans: vitamin K substances. World Health Organization publication, 76, 417–82
- Iwamoto J, Takeda T, Sato Y. (2006). Role of vitamin K2 in the treatment of postmenopausal osteoporosis. Curr Drug Saf, 1, 87–97
- Jie KG, Bots ML, Vermeer C, et al. (1996). Vitamin K status and bone mass in women with and without aortic atherosclerosis: a population-based study. Calcif Tissue Int, 59, 352–6
- Kaneki M, Mizuno Y, Hosoi T, et al. (1995). Serum concentration of vitamin K in elderly women with involutional osteoporosis. Nihon Ronen Igakkai Zasshi, 32, 195–200
- Knapen MHJ, Drummen NE, Smit E, et al. (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporos Int, 24, 2499–507
- Krishna C. (2005). Solid-state fermentation systems-an overview. Crit Rev Biotechnol, 25, 1–30
- Kuchma SL, O’Toole GA. (2000). Surface-induced and biofilm-induced changes in gene expression. Curr Opin Biotechnol, 11, 429–33
- Li J, Lin JC, Wang H, et al. (2003). Novel role of vitamin K in preventing oxidative injury to developing oligodendrocytes and neurons. J Neurosci, 23, 5816–26
- Lloyd-Jones D, Adams RJ, Brown TM, et al. (2010). Executive summary: heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation, 121, 948–54
- Mahanama R, Berenjian A, Talbot A, et al. (2011a). Enhanced production of menaquinone 7 via solid substrate fermentation from Bacillus subtilis. Int J Food Eng, 7, Article 17
- Mahanama R, Berenjian A, Talbot A, et al. (2011b). Solid-substrate fermentation of menaquinone 7 with Bacillus subtilis: comparison of continuous rotation with stationary bed fermentation at different initial moisture levels. Proceedings of Chemeca; 2011; Sydney, NSW: Engineers Australia, 315–24
- Mahanama R, Berenjian A, Talbot A, et al. (2012a). Modeling Menaquinone 7 production in tray type solid state fermenter. ANZIAM J, 53, 354–72
- Mahanama R, Berenjian A, Dehghani F, Kavanagh J. (2012b). Modeling the effect of bed height and particle size for vitamin K2 production in a static bed fermenter. Eng Lett, 20, 16–9
- McFarlane SI, Muniyappa R, Shin JJ, et al. (2004). Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link? Endocr, 23, 1–10
- Meganathan R. (2001). Ubiquinone biosynthesis in microorganisms. FEMS Microbiol Lett, 61, 173–218
- Miki T, Nakatsuka K, Naka H, et al. (2003). Vitamin K 2 (menaquinone 4) reduces serum undercarboxylated osteocalcin level as early as 2 weeks in elderly women with established osteoporosis. J Bone Miner Metab, 21, 161–5
- Mitchell DA, Berovic M, Krieger N. (2000). Biochemical engineering aspects of solid state bioprocessing. Adv Biochem Eng Biotechnol, 68, 61–138
- Morishita T, Tamura N, Makino T, Kudo S. (1999). Production of menaquinone by lactic acid bacteria. J Dairy Sci, 82, 1897–903
- Nattopharma (2012). Annual Report. Available from: http://www.nattopharma.com/2012.html [last accessed 30 Aug 2013]
- Orimo H, Nakamura T, Hosoi T, et al. (2012). Japanese 2011 guidelines for prevention and treatment of osteoporosis-executive summary. Arch Osteoporos, 7, 3–20
- Ozuru R, Sugimoto T, Yamaguchi T, Chihara K. (2002). Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women. Endocr, 49, 363–70
- Pandey A. (1992). Recent process developments in solid-state fermentation. Process Biochem, 27, 109–17
- Piironen V, Koivu T, Tammisalo O, Mattila P. (1997). Determination of phylloquinone in oils, margarines and butter by high-performance liquid chromatography with electrochemical detection. Food Chem, 59, 473–80
- Quinlan PT. (2007). Unilever res vlaardingen. Vitamin k2 containing food product. European Patent 1153548
- Rajagopalan S, Modak J. (1995). Modeling of heat and mass transfer for solid state fermentation process in tray bioreactor. Bioprocess Biosyst Eng, 13, 161–9
- Sato T, Yamada Y, Ohtani Y, et al. (2001a). Efficient production of menaquinone (vitamin K2) by a menadione-resistant mutant of Bacillus subtilis. J Ind Microbiol Biotechnol, 26, 115–20
- Sato T, Yamada Y, Ohtani Y, et al. (2001b). Production of Menaquinone (vitamin K2)-7 by Bacillus subtilis. J Biosci Bioeng, 91, 16–20
- Schallmey M, Singh A, Ward OP. (2004). Developments in the use of Bacillus species for industrial production. Can J Microbiol, 50, 1–17
- Schurgers LJ, Teunissen KJ, Hamulyák K, et al. (2007). Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 109, 3279–83
- Sennerby U, Melhus H, Gedeborg R, et al. (2009). Cardiovascular diseases and risk of hip fracture. JAMA, 302, 1666–73
- Seto H, Jinnai Y, Hiratsuka T, et al. (2008). Studies on a new biosynthetic pathway for menaquinone. J Am Chem Soc, 130, 5614–5
- Shahidi F. (2006). Nutraceutical and specialty lipids and their co-products. Boca Raton, FL: CRC Press/Taylor Francis
- Shea MK, Holden RM. (2012). Vitamin K status and vascular calcification: evidence from observational and clinical studies. Adv Nutr, 3, 158–65
- Shearer MJ. (1992). Vitamin K metabolism and nutriture. Blood Rev, 6, 92–104
- Shearer MJ, Newman P. (2008). Metabolism and cell biology of vitamin K. J Thromb Haemost, 100, 530–47
- Shiraki M, Shiraki Y, Aoki C, Miura M. (2000). Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res, 15, 515–21
- Skattebol L, Aukrust IR. (2010). Process for the preparation of vitamin K2. European Patent 2346806 A1
- Sonenshein AL, Hoch JA, Losick R. (2002). Bacillus subtilis and its closest relatives. Washington, DC: ASM Press
- Sumi H. (2004). Edible compositions of Bacillus subtilis natto cells containing water-soluble vitamin K. US Patent 6677141
- Sumi H, Asano N, Yatagai C. (2005). Additional effect of some nutrients and biological-active substances by Bacillus natto treatment of raw wheat. J Brew Japan, 100, 449–53
- Survase S, Bajaj I, Singhai RS. (2006). Biotechnological production of vitamins. Food Technol Biotech, 44, 381–96
- Suttie JW. (1995). The importance of menaquinone in human nutrition. Annu Rev Nutr, 15, 399–417
- Suvarna K, Stevenson D, Meganathan R, Hudspeth ME. (1998). Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menA gene from Escherichia coli. J Bacteriol, 180, 2782–7
- Takenaka T, Inoue S, Takenaka Y, et al. (2002). Effects of vitamin K2 (menaquinone-7) from fermented okara on ALPase activity of human dental pulp. Nippon Shokuhin Kagaku Kogaku Kaishi, 49, 348–52
- Tamatani M, Morimoto S, Nakajima M, et al. (1998). Decreased circulating levels of vitamin K and 25-hydroxyvitamin D in osteopenic elderly men. Metabolism, 47, 195–9
- Tani Y, Asahi S, Yamada H. (1984). Vitamin K2 (menaquinone): screening of producing microorganisms and production by Flavobacterium meningosepticurn. J Ferment Technol, 62, 321–7
- Tani Y, Taguchi H. (1989). Extracellular production of menaquinone-4 by a mutant of Flavobacterium sp. 238-7 with a detergent-supplemented culture. J Biosci Bioeng, 67, 102–6
- Tankó LB, Christiansen C, Cox DA, et al. (2005). Relationship between osteoporosis and cardiovascular disease in postmenopausal women. J Bone Miner Res, 20, 1912–20
- Truong JT, Booth SL. (2011). Emerging issues in vitamin K research. J Evid Based Complementary Altern Med, 16, 73–9
- Tsukamoto Y, Ichise H, Kakuda H, Yamaguchi M. (2000a). Intake of fermented soybean (natto) increases circulating vitamin K2 (menaquinone-7) and γ-carboxylated osteocalcin concentration in normal individuals. J Bone Miner Metab, 18, 216–22
- Tsukamoto Y, Ichise H, Yamaguchi M. (2000b). Prolonged intake of dietary fermented soybeans (Natto) with the reinforced vitamin K2 (menaquinone-7) enhances circulating gamma-carboxylated osteocalcin concentration in normal individuals. J Health Sci, 46, 317–21
- Tsukamoto Y, Kasai M, Kakuda H. (2001). Construction of a Bacillus subtilis (natto) with high productivity of vitamin K2 (menaquinone-7) by analog resistance. Biosci Biotechnol Biochem, 65, 2007–15
- Usui Y, Tanimura H, Nishimura N, et al. (1990). Vitamin K concentrations in the plasma and liver of surgical patients. Am J Clin Nutr, 51, 846–52
- Van Brunt J. (1988). Scale-up: how big is big enough? Biotechnol, 6, 480–5
- Vermeer C, Braam L. (2001). Role of K vitamins in the regulation of tissue calcification. J Bone Miner Metab, 19, 201–6
- Vermeer C. (2012). Vitamin K: the effect on health beyond coagulation–an overview. Food Nutr Res, 56, 166--173
- Weber FJ, Tramper J, Rinzema A. (1999). A simplified material and energy balance approach for process development and scale-up of Coniothyrium minitans conidia production by solid-state cultivation in a packed-bed reactor. Biotechnol Bioeng, 65, 447–58
- Weber FJ, Oostra J, Tramper J, Rinzema A. (2002). Validation of a model for process development and scale-up of packed-bed solid-state bioreactors. Biotechnol Bioeng, 77, 381–93
- WHO. (2011). Global atlas on cardiovascular disease prevention and control. Avaible at: http://www.who.int/cardiovascular_diseases/publications/atlas_cvd/en/index.html
- Wu CH, Chou CC. (2009). Enhancement of aglycone, vitamin K2 and superoxide dismutase activity of black soybean through fermentation with Bacillus subtilis BCRC 14715 at different temperatures. J Agric Food Chem, 57, 10695–700
- Wu WJ. (2011). Food science/microbiology: isolation and identification of Bacillus amyloliquefaciens BY01 with high productivity of menaquinone for cheonggukjang production. J Korean Soc Appl Biol Chem, 54, 783–9
- Wu WJ, Ahn BY. (2011a). Improved menaquinone (Vitamin K 2) production in cheonggukjang by optimization of the fermentation conditions. Food Sci Biotechnol, 20, 1585–91
- Wu WJ, Ahn BY. (2011b). Isolation and identification of Bacillus amyloliquefaciens BY01 with high productivity of menaquinone for cheonggukjang production. J Korean Soc Appl Bi, 54, 783–9
- Yamaguchi M, Hideaki T, Gao YH, et al. (1999). Effect of vitamin K2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovariectomized rats. J Bone Miner Metab, 17, 23--29
- Yang ST. (2007). Bioprocessing for value-added products from renewable resources: new technologies and applications. Dublin, OH: Elsevier Science Publication
- Zadražil F, Brunnert H. (1981). Investigation of physical parameters important for the solid state fermentation of straw by white rot fungi. Appl Microbiol Biotechnol, 11, 183–8