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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 30, 2013 - Issue 9
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Research Article

Sex Differences in the Circadian Variation of Cytochrome P450 Genes and Corresponding Nuclear Receptors in Mouse Liver

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Pages 1135-1143 | Received 27 Mar 2013, Accepted 13 May 2013, Published online: 08 Aug 2013

References

  • Bozek K, Rosahl AL, Gaub S, et al. (2010). Circadian transcription in liver. Biosystems, 102, 61–9
  • Bruckner JV, Ramanathan R, Lee KM, Muralidhara S. (2002). Mechanisms of circadian rhythmicity of carbon tetrachloride hepatotoxicity. J Pharmacol Exp Ther, 300, 273–81
  • Bur IM, Cohen-Solal AM, Carmignac D, et al. (2009). The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism. J Biol Chem, 284, 9066–73
  • Chiang JY. (2009). Bile acids: regulation of synthesis. J Lipid Res, 50, 1955–66
  • Corton JC, Bushel PR, Fostel J, O’Lone RB. (2012). Sources of variance in baseline gene expression in the rodent liver. Mutat Res, 746, 104–12
  • Dibner C, Schibler U, Albrecht U. (2010). The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol, 72, 517–49
  • Duez H, van der Veen JN, Duhem C, et al. (2008). Regulation of bile acid synthesis by the nuclear receptor Rev-erb alpha. Gastroenterology, 135, 689–98
  • Filipski E, Subramanian P, Carrière J, et al. (2009). Circadian disruption accelerates liver carcinogenesis in mice. Mutat Res, 680, 95–105
  • Froy O. (2009). Cytochrome P450 and the biological clock in mammals. Curr Drug Metab, 10, 104–15
  • Froy O. (2011). The circadian clock and metabolism. Clin Sci, 120, 65–72
  • Fu ZD, Csanaky IL, Klaassen CD. (2012). Gender-divergent profile of bile acid homeostasis during aging of mice. PLoS ONE, 7, e32551
  • Gachon F, Firsov D. (2011). The role of circadian timing system on drug metabolism and detoxification. Expert Opin Drug Metab Toxicol, 7, 147–58
  • Hernandez JP, Mota LC, Huang W, et al. (2009). Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). Toxicology, 256, 53–64
  • Hirao J, Nishimura M, Arakawa S, et al. (2011). Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses. J Toxicol Sci, 36, 9–22
  • Huang P, Ceccatelli S, Rannug A. (2002). A study on diurnal mRNA expression of CYP1A1, AHR, ARNT, and PER2 in rat pituitary and liver. Environ Toxicol Pharmacol, 11, 119–26
  • Kakan X, Chen P, Zhang J. (2011). Clock gene mPer2 functions in diurnal variation of acetaminophen induced hepatotoxicity in mice. Exp Toxicol Pathol, 63, 581–5
  • Khemawoot P, Nishino K, Ishizaki J, et al. (2007). Circadian rhythm of cytochrome P4502E1 and its effect on disposition kinetics of chlorzoxazone in rats. Eur J Pharmacol, 574, 71–6
  • Lavery DJ, Lopez-Molina L, Margueron R, et al. (1999). Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP. Mol Cell Biol, 19, 6488–99
  • Le Martelot G, Claudel T, Gatfield D, et al. (2009). REV-ERB alpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol, 7, e1000181
  • Levi F, Schibler U. (2007). Circadian rhythms:mechanisms andtherapeutic implications. Annu Rev Pharmacol Toxicol, 47, 593–628
  • Lim FL, Currie RA, Orphanides G, Moggs JG. (2006). Emerging evidence for the interrelationship of xenobiotic exposure and circadian rhythms: a review. Xenobiotica, 36, 1140–51
  • Ma K, Xiao R, Tseng HT, et al. (2009). Circadian dysregulation disrupts bile acid homeostasis. PLoS ONE, 4, e6843
  • Maddrey WC. (2005). Drug-induced hepatotoxicity. J Clin Gastroenterol, 39, S83–9
  • Matsunaga N, Ikeda M, Takiguchi T, et al. (2008). The molecular mechanism regulating 24-hour rhythm of CYP2E1 expression in the mouse liver. Hepatology, 48, 240–51
  • Noshiro M, Usui E, Kawamoto T, et al. (2007). Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis. J Biol Rhythms, 22, 299–311
  • Ohno M, Yamaguchi I, Ito T, et al. (2000). Circadian variation of the urinary 6beta-hydroxycortisol to cortisol ratio that would reflect hepatic CYP3A activity. Eur J Clin Pharmacol, 55, 861–5
  • Oishi K, Shirai H, Ishida N. (2005). CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor alpha (PPARalpha) in mice. Biochem J, 386, 575–81
  • Oishi K, Uchida D, Ohkura N, Horie S. (2010). PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver. Biochem Biophys Res Commun, 401, 313–18
  • Paschos GK, Baggs JE, Hogenesch JB, FitzGerald GA. (2010). The role of clock genes in pharmacology. Annu Rev Pharmacol Toxicol, 50, 87–214
  • Petrick JS, Klaassen CD. (2007). Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport. Drug Metab Dispos, 35, 1806–15
  • Portaluppi F, Smolensky MH, Touitou Y. (2010). Ethics and methods for biological rhythm research on animals and human beings. Chronobiol Int, 27, 1911–29
  • Qu X, Metz RP, Porter WW, et al. (2009). Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver. Toxicol Appl Pharmacol, 34, 370–7
  • Qu X, Metz RP, Porter WW, et al. (2010). The clock genes period 1 and period 2 mediate diurnal rhythms in dioxin-induced Cyp1A1 expression in the mouse mammary gland and liver. Toxicol Lett, 196, 28–32
  • Refinetti R, Cornélissen G, Halberg F. (2007). Procedures for numerical analysis of circadian rhythms. Biol Rhythm Res, 38, 235–325
  • Renaud HJ, Cui JY, Khan M, Klaassen CD. (2011). Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice. Toxicol Sci, 124, 261–77
  • Sekimoto M. (2011). Sex- and species-differences on xenobiotic-induced toxicity: differences in constitutive and xenobiotic-mediated expression of cytochrome P450 1A subfamily enzymes (CYP1As). Yakugaku Zasshi, 131, 415–22
  • Sukumaran S, Almon RR, DuBois DC, Jusko WJ. (2010). Circadian rhythms in gene expression: relationship to physiology, disease, drug disposition and drug action. Adv Drug Deliv Rev, 62, 904–17
  • Tanimura N, Kusunose N, Matsunaga N, et al. (2011). Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner. Toxicology, 290, 203–7
  • Waxman DJ, O’Connor C. (2006). Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol, 11, 2613–29
  • Xu CX, Krager SL, Liao DF, Tischkau SA. (2010). Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene. Toxicol Sci, 115, 98–108
  • Xu YQ, Zhang D, Jin T, et al. (2012). Diurnal variation of hepatic antioxidant gene expression in mice. PLoS ONE, 7, e44237
  • Zhang D, Jin T, Xu YQ, et al. (2012). Diurnal-and sex-related difference of metallothionein expression in mice. J Circadian Rhythms, 10, 5. [Epub ahead of print]
  • Zhang YK, Yeager RL, Klaassen CD. (2009). Circadian expression profiles of drug-processing genes and transcription factors in mouse liver. Drug Metab Dispos, 37, 106–15
  • Zhang YK, Guo GL, Klaassen CD. (2011). Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters. PLoS ONE, 6, e16683
  • Zmrzljak UP, Rozman D. (2012). Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters. Chem Res Toxicol, 25, 811–24

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