Genetic polymorphisms of DAT1 and COMT differentially associate with actigraphy-derived sleep–wake cycles in young adults

References

• Akil M, Kolachana BS, Rothmond DA, et al. (2003). Catechol-O-methyltransferase genotype and dopamine regulation in the human brain. J Neurosci. 23:2008–13
   PubMed Web of Science ®Google Scholar
• Annerbrink K, Westberg L, Nilsson S, et al. (2008). Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men. Metabolism. 57:708–11
   PubMed Web of Science ®Google Scholar
• Barkley RA, Smith KM, Fischer M, Navia B. (2006). An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBH TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthood. Am J Med Genet B Neuropsychiatr Genet. 141B:487–98
   PubMed Web of Science ®Google Scholar
• Bodenmann S, Landolt HP. (2010). Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT. Sleep. 33:1027–35
   PubMed Web of Science ®Google Scholar
• Bodenmann S, Xu S, Luhmann UF, et al. (2009). Pharmacogenetics of modafinil after sleep loss: Catechol-O-methyltransferase genotype modulates waking functions but not recovery sleep. Clin Pharmacol Ther. 85:296–304
   PubMed Web of Science ®Google Scholar
• Boonstra AM, Kooij JJ, Oosterlaan J, et al. (2007). Hyperactive night and day? Actigraphy studies in adult ADHD: A baseline comparison and the effect of methylphenidate. Sleep. 30:433–42
   PubMed Web of Science ®Google Scholar
• Borbely AA. (1982). A two process model of sleep regulation. Hum Neurobiol. 1:195–204
   PubMedGoogle Scholar
• Chen J, Lipska BK, Halim N, et al. (2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet. 75:807–21
   PubMed Web of Science ®Google Scholar
• Cheon KA, Ryu YH, Kim YK, et al. (2003). Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. Eur J Nucl Med Mol Imaging. 30:306–11
   PubMed Web of Science ®Google Scholar
• Ciliax BJ, Heilman C, Demchyshyn LL, et al. (1995). The dopamine transporter: Immunochemical characterization and localization in brain. J Neurosci. 15:1714–23
   PubMed Web of Science ®Google Scholar
• Cohen-Zion M, Ancoli-Israel S. (2004). Sleep in children with attention-deficit hyperactivity disorder (ADHD): A review of naturalistic and stimulant intervention studies. Sleep Med Rev. 8:379–402
   PubMed Web of Science ®Google Scholar
• Comella CL. (2008). Sleep disorders in Parkinson's disease. Curr Treat Options Neurol. 10:215–21
   PubMed Web of Science ®Google Scholar
• Cortese S, Faraone SV, Konofal E, Lecendreux M. (2009). Sleep in children with attention-deficit/hyperactivity disorder: Meta-analysis of subjective and objective studies. J Am Acad Child Adolesc Psychiatry. 48:894–908
   PubMed Web of Science ®Google Scholar
• Costa A, Riedel M, Muller U, et al. (2011). Relationship between SLC6A3 genotype and striatal dopamine transporter availability: A meta-analysis of human single photon emission computed tomography studies. Synapse. 65:998–1005
   PubMed Web of Science ®Google Scholar
• Dauvilliers Y, Neidhart E, Billiard M, Tafti M. (2002). Sexual dimorphism of the catechol-O-methyltransferase gene in narcolepsy is associated with response to modafinil. Pharmacogenomics J. 2:65–8
   PubMedGoogle Scholar
• Dauvilliers Y, Neidhart E, Lecendreux M, et al. (2001). MAO-A and COMT polymorphisms and gene effects in narcolepsy. Mol Psychiatry. 6:367–72
   PubMed Web of Science ®Google Scholar
• Dougherty DD, Bonab AA, Spencer TJ, et al. (1999). Dopamine transporter density in patients with attention deficit hyperactivity disorder. Lancet. 354:2132–3
   PubMed Web of Science ®Google Scholar
• Dreher JC, Schmidt PJ, Kohn P, et al. (2007). Menstrual cycle phase modulates reward-related neural function in women. Proc Natl Acad Sci USA. 104:2465–70
   PubMed Web of Science ®Google Scholar
• Dresel S, Krause J, Krause KH, et al. (2000). Attention deficit hyperactivity disorder: Binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment. Eur J Nucl Med. 27:1518–24
   PubMedGoogle Scholar
• Franke B, Vasquez AA, Johansson S, et al. (2010). Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology. 35:656–64
   PubMed Web of Science ®Google Scholar
• Galvao AC, Kruger RC, Campagnolo PD, et al. (2012). Association of MAOA and COMT gene polymorphisms with palatable food intake in children. J Nutr Biochem. 23:272–7
   PubMed Web of Science ®Google Scholar
• Giros B, Jaber M, Jones SR, et al. (1996). Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379:606–12
   PubMed Web of Science ®Google Scholar
• Gruber R, Grizenko N, Schwartz G, et al. (2006). Sleep and COMT polymorphism in ADHD children: Preliminary actigraphic data. J Am Acad Child Adolesc Psychiatry. 45:982–9
   PubMed Web of Science ®Google Scholar
• Heinz A, Goldman D, Jones DW, et al. (2000). Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology. 22:133–9
   PubMed Web of Science ®Google Scholar
• Holst SC, Bersagliere A, Bachmann V, et al. (2014). Dopaminergic role in regulating neurophysiological markers of sleep homeostasis in humans. J Neurosci. 34:566–73
   Google Scholar
• Hosak L. (2007). Role of the COMT gene Val158Met polymorphism in mental disorders: A review. Eur Psychiatry. 22:276–81
   PubMed Web of Science ®Google Scholar
• Jacobsen LK, Staley JK, Zoghbi SS, et al. (2000). Prediction of dopamine transporter binding availability by genotype: A preliminary report. Am J Psychiatry. 157:1700–3
   PubMed Web of Science ®Google Scholar
• Johns MW. (1991). A new method for measuring daytime sleepiness: The Epworth sleepiness scale. Sleep. 14:540–5
   PubMed Web of Science ®Google Scholar
• Johns MW. (2000). Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth sleepiness scale: Failure of the MSLT as a gold standard. J Sleep Res. 9:5–11
   PubMed Web of Science ®Google Scholar
• Kang AM, Palmatier MA, Kidd KK. (1999). Global variation of a 40-bp VNTR in the 3′-untranslated region of the dopamine transporter gene (SLC6A3). Biol Psychiatry. 46:151–60
   PubMed Web of Science ®Google Scholar
• Kereszturi E, Tarnok Z, Bognar E, et al. (2008). Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. Am J Med Genet B Neuropsychiatr Genet. 147B:1431–5
   PubMed Web of Science ®Google Scholar
• Krause J, Dresel SH, Krause KH, et al. (2006). Striatal dopamine transporter availability and DAT-1 gene in adults with ADHD: No higher DAT availability in patients with homozygosity for the 10-repeat allele. World J Biol Psychiatry. 7:152–7
   PubMed Web of Science ®Google Scholar
• Kume K, Kume S, Park SK, et al. (2005). Dopamine is a regulator of arousal in the fruit fly. J Neurosci. 25:7377–84
   PubMed Web of Science ®Google Scholar
• Kurian MA, Zhen J, Cheng SY, et al. (2009). Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile Parkinsonism-Dystonia. J Clin Invest. 119:1595–603
   PubMed Web of Science ®Google Scholar
• Lazar AS, Slak A, Lo JC, et al. (2012). Sleep, diurnal preference, health, and psychological well-being: A prospective single-allelic-variation study. Chronobiol Int. 29:131–46
   PubMed Web of Science ®Google Scholar
• Lazarus M, Chen JF, Urade Y, Huang ZL. (2013). Role of the basal ganglia in the control of sleep and wakefulness. Curr Opin Neurobiol. 23:780–5
   PubMed Web of Science ®Google Scholar
• Lu J, Jhou TC, Saper CB. (2006). Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter. J Neurosci. 26:193–202
   PubMed Web of Science ®Google Scholar
• Meyer-Lindenberg A, Kohn PD, Kolachana B, et al. (2005). Midbrain dopamine and prefrontal function in humans: Interaction and modulation by COMT genotype. Nat Neurosci. 8:594–96
   PubMed Web of Science ®Google Scholar
• Michelhaugh SK, Fiskerstrand C, Lovejoy E, et al. (2001). The dopamine transporter gene (SLC6A3) variable number of tandem repeats domain enhances transcription in dopamine neurons. J Neurochem. 79:1033–8
   PubMed Web of Science ®Google Scholar
• Miller GM, Madras BK. (2002). Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression. Mol Psychiatry. 7:44–55
   PubMed Web of Science ®Google Scholar
• Minzenberg MJ. (2012). Pharmacotherapy for attention-deficit/hyperactivity disorder: From cells to circuits. Neurotherapeutics. 9:610–21
   PubMed Web of Science ®Google Scholar
• Monti JM, Monti D. (2007). The involvement of dopamine in the modulation of sleep and waking. Sleep Med Rev. 11:113–33
   PubMed Web of Science ®Google Scholar
• Morgenthaler T, Alessi C, Friedman L, et al. (2007). Practice parameters for the use of actigraphy in the assessment of sleep and sleep disorders: An update for 2007. Sleep. 30:519–29
   PubMed Web of Science ®Google Scholar
• Munro CA, McCaul ME, Wong DF, et al. (2006). Sex differences in striatal dopamine release in healthy adults. Biol Psychiatry. 59:966–74
   PubMed Web of Science ®Google Scholar
• Nakamura Y, Koyama K, Matsushima M. (1998). VNTR (variable number of tandem repeat) sequences as transcriptional, translational, or functional regulators. J Hum Genet. 43:149–52
   PubMed Web of Science ®Google Scholar
• Need AC, Ahmadi KR, Spector TD, Goldstein DB. (2006). Obesity is associated with genetic variants that alter dopamine availability. Ann Hum Genet. 70:293–303
   PubMed Web of Science ®Google Scholar
• Pico C, Puigserver P, Oliver P, Palou A. (1998). 2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation. Mol Cell Biochem. 189:1–7
   PubMed Web of Science ®Google Scholar
• Portaluppi F, Smolensky MH, Touitou Y. (2010). Ethics and methods for biological rhythm research on animals and human beings. Chronobiol Int. 27:1911–29
   PubMed Web of Science ®Google Scholar
• Qu WM, Xu XH, Yan MM, et al. (2010). Essential role of dopamine D2 receptor in the maintenance of wakefulness, but not in homeostatic regulation of sleep, in mice. J Neurosci. 30:4382–9
   PubMed Web of Science ®Google Scholar
• Roenneberg T, Allebrandt KV, Merrow M, Vetter C. (2012). Social jetlag and obesity. Curr Biol. 22:939–43
   PubMed Web of Science ®Google Scholar
• Roenneberg T, Wirz-Justice A, Merrow M. (2003). Life between clocks: Daily temporal patterns of human chronotypes. J Biol Rhythms. 18:80–90
   PubMed Web of Science ®Google Scholar
• Rousset F. (2008). genepop'007: A complete re-implementation of the genepop software for Windows and Linux. Mol Ecol Resour. 8:103–6
   PubMed Web of Science ®Google Scholar
• Rye DB, Freeman AAH. (2011). Dopaminergic substrates underlying hypersomnia, sleepiness, and REM sleep expression. In: Baumann CR, Bassetti CL, Scammell TE, eds. Narcolepsy: Pathophysiology, diagnosis, and treatment. New York: Springer Science+Business Media, pp. 64–71
   Google Scholar
• Rye DB, Jankovic J. (2002). Emerging views of dopamine in modulating sleep/wake state from an unlikely source: PD. Neurology. 58:341–6
   PubMed Web of Science ®Google Scholar
• Sadeh A. (2011). The role and validity of actigraphy in sleep medicine: An update. Sleep Med Rev. 15:259–67
   PubMed Web of Science ®Google Scholar
• Schwartz MW, Woods SC, Porte Jr D, et al. (2000). Central nervous system control of food intake. Nature. 404:661–71
   PubMed Web of Science ®Google Scholar
• Spencer TJ, Biederman J, Faraone SV, et al. (2013). Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biol Psychiatry. 74:84–9
   Google Scholar
• Spencer TJ, Biederman J, Madras BK, et al. (2005). In vivo neuroreceptor imaging in attention-deficit/hyperactivity disorder: A focus on the dopamine transporter. Biol Psychiatry. 57:1293–300
   PubMed Web of Science ®Google Scholar
• Spiegel K, Tasali E, Leproult R, Van Cauter E. (2009). Effects of poor and short sleep on glucose metabolism and obesity risk. Nature Rev Endocrinol. 5:253–61
   PubMed Web of Science ®Google Scholar
• Surman CB, Adamson JJ, Petty C, et al. (2009). Association between attention-deficit/hyperactivity disorder and sleep impairment in adulthood: Evidence from a large controlled study. J Clin Psychiatry. 70:1523–9
   PubMed Web of Science ®Google Scholar
• Tonetti L, Pasquini F, Fabbri M, et al. (2008). Comparison of two different actigraphs with polysomnography in healthy young subjects. Chronobiol Int. 25:145–53
   PubMed Web of Science ®Google Scholar
• Tunbridge EM, Harrison PJ, Weinberger DR. (2006). Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biol Psychiatry. 60:141–51
   PubMed Web of Science ®Google Scholar
• Tworoger SS, Chubak J, Aiello EJ, et al. (2004). The effect of CYP19 and COMT polymorphisms on exercise-induced fat loss in postmenopausal women. Obes Res. 12:972–81
   PubMedGoogle Scholar
• Ueno T, Tomita J, Tanimoto H, et al. (2012). Identification of a dopamine pathway that regulates sleep and arousal in Drosophila. Nat Neurosci. 15:1516–23
   Google Scholar
• van de Giessen E, de Win MM, Tanck MW, et al. (2009). Striatal dopamine transporter availability associated with polymorphisms in the dopamine transporter gene SLC6A3. J Nucl Med. 50:45–52
   PubMed Web of Science ®Google Scholar
• van Dyck CH, Malison RT, Jacobsen LK, et al. (2005). Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene. J Nucl Med. 46:745–51
   PubMed Web of Science ®Google Scholar
• Van Someren EJ, Swaab DF, Colenda CC, et al. (1999). Bright light therapy: Improved sensitivity to its effects on rest-activity rhythms in Alzheimer patients by application of nonparametric methods. Chronobiol Int. 16:505–18
   PubMed Web of Science ®Google Scholar
• Van Veen MM, Kooij JJ, Boonstra AM, et al. (2010). Delayed circadian rhythm in adults with attention-deficit/hyperactivity disorder and chronic sleep-onset insomnia. Biol Psychiatry. 67:1091–6
   PubMed Web of Science ®Google Scholar
• Vandenbergh DJ, Persico AM, Hawkins AL, et al. (1992). Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics. 14:1104–6
   PubMed Web of Science ®Google Scholar
• Wang GJ, Volkow ND, Logan J, et al. (2001). Brain dopamine and obesity. Lancet. 357:354–7
   PubMed Web of Science ®Google Scholar
• Whitehead DL, Davies AD, Playfer JR, Turnbull CJ. (2008). Circadian rest-activity rhythm is altered in Parkinson's disease patients with hallucinations. Mov Disord. 23:1137–45
   PubMed Web of Science ®Google Scholar
• Wise RA, Bozarth MA. (1987). A psychomotor stimulant theory of addiction. Psychol Rev. 94:469–92
   PubMed Web of Science ®Google Scholar
• Wisor JP, Nishino S, Sora I, et al. (2001). Dopaminergic role in stimulant-induced wakefulness. J Neurosci. 21:1787–94
   PubMed Web of Science ®Google Scholar