Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 3, 1986 - Issue 3
11
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Circadian Modification of 5-Fluorouracil-Induced Teratogenesis in Mice

Pages 161-164 | Received 01 Oct 1985, Accepted 01 Apr 1986, Published online: 07 Jul 2009

References

  • Scheving L. E., Mayersbach H., Pauly J. E. An overview of chronopharmacology. Eur J Toxicol 1974; 7: 203–227
  • Mayersbach H. Time—A key in experimental and practical medicine. Arch Toxicol 1976; 36: 185–216
  • Reinberg A., Smolensky M. H. Circadian changes of drug disposition in man. Clin Pharmacokinet 1982; 7: 401–420
  • Isaacson R. J. Investigation of some of the factors involved in the closure of the secondary palate. University of Minnesota, Minneapolis, Minnesota 1959, Ph.D. thesis
  • Clayton D. L., McMullen A. W., Barnett C. C. Circadian modification of drug-induced teratogenesis in rat fetuses. Chronobiologia 1975; 2: 210–217
  • Schmidt R. Zur zirkadianen Modifikation der pränatal-toxischen Wirkung von Cyclophosphamid. Biol Rdsch 1978; 16: 243–248
  • Sauerbier I. Circadian system and teratogenicity of cytostatic drugs. Prog Clin Biol Res 1981; 59, C, 143–149
  • Sauerbier I. Embryotoxische Wirkung von Zytostatika in Abhängigkeit vom Tageszeitpunkt der Applikation bei Mäusen. Verh Anat Ges 1983; 77: 147–149
  • Sauerbier I. Circadian variation in teratogenic response to dexamethasone in mice. Drug Chem Toxicol, in press.
  • Karnofski D. A., Murphy M. L., Lacon C. R. Comparative toxicologic and teratogenic effects of 5-fluoro substituted pyrimidines in the chick embryo and pregnant rat. (Abstract). Proc Am Assoc Cancer Res 1958; 2: 312–313
  • Dagg C. P. Sensitive stages for the production of developmental abnormalities in mice with 5-fluorouracil. Am J Anat 1960; 106: 89–96
  • Chaube S., Murphy M. L. The teratogenic effects of the recent drugs active in cancer chemotherapy. Adv Teratol 1968; 3: 181–235
  • Wilson J. G. Use of rhesus monkeys in teratological studies. Fed Proc 1971; 30: 104–109
  • Imagawa S. Symbrachydactyly: pathogenesis of 5-fluorouracil induced model in mice. Hiroshima J Med Sci 1980; 29: 169–181
  • Dawson A. B. A note on the staining of the skeleton of cleared specimens with alizarin red A. Stain Technol 1926; 1: 123–124
  • Sachs L. Statistische Methoden. Springer, Berlin 1982
  • Yasuda M., Nakamura H. Pathogenesis of limb malformations in mice: an electron microscopic study. Prog Clin Biol Res 1983; 110A: 301–310
  • Rugh R. The Mouse, Its Reproduction and Development. Burgess, Minneapolis 1968
  • Gardner M. L., Plumb J. A. Diural variation in the intestinal toxicity of 5-fluorouracil in the rat. Clin Sci 1981; 61: 717–722
  • Burns E. R., Beland S. S. Effect of biological time on the determination of the LD50 of 5-fluorouracil in mice. Pharmacology 1984; 28: 296–300

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.