Molecular Mechanisms of Actions of Formulations of the Thyroid Hormone Analogue, Tetrac, on the Inflammatory Response

REFERENCES

• De Vito P, Incerpi S, Pedersen J Z, . Thyoid hormones as modulators of immune activities at the cellular level. Thyroid 2011;21:879–890.
   PubMed Web of Science ®Google Scholar
• De Vito P, Balducci V, Leone S, . Nongenomic effects of thyroid hormones on the immune system cells: new targets, old players. Steroids 2012;77:988–995.
   PubMed Web of Science ®Google Scholar
• Davis FB, Mousa SA, O’Connor L, . Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circ Res 2004;94:1500–1508.
   PubMed Web of Science ®Google Scholar
• Bergh JJ, Lin HY, Lansing L, . Integrin alphavbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology 2005;146:2864–2871.
   PubMed Web of Science ®Google Scholar
• Luidens MK, Mousa SA, Davis FB, . Thyroid hormone and angiogenesis. Vasc Pharmacol 2010;52:142–145.
   PubMed Web of Science ®Google Scholar
• Davis PJ, Davis FB, Mousa SA, . Membrane receptor for thyroid hormone: physiologic and pharmacologic implications. Annu Rev Pharmacol Toxicol 2011;51:99–115.
   PubMed Web of Science ®Google Scholar
• Cheng SY, Leonard JL, Davis PJ. Molecular aspects of thyroid hormone actions. Endocr Rev 2010;31:139–170.
   PubMed Web of Science ®Google Scholar
• Moreno M, de Lange P, Lombardi A, . Metabolic effects of thyroid hormone derivatives. Thyroid 2008;18:239–253.
   PubMed Web of Science ®Google Scholar
• Malm J, Farnegardh M, Grover GJ, . Thyroid hormone antagonists: potential medical applications and structure activity relationships. Curr Med Chem 2009;16:3258–3266.
   PubMed Web of Science ®Google Scholar
• Mousa SA, Bergh JJ, Dier E, . Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis by vascular endothelial growth factor and basic fibroblast growth factor. Angiogenesis 2008;11:183–190.
   PubMed Web of Science ®Google Scholar
• Voronov E, Carmi Y, Apte RN. Role of IL-1-mediated inflammation in tumor angiogenesis. Adv Exp Med Biol 2007;601:265–270.
   PubMed Web of Science ®Google Scholar
• Siddiqi A, Burrin JM, Wood DF, . Tri-iodothyronine regulates the production of interleukin-6 and interleukin-8 in human bone marrow stromal and osteoblast-like cells. J Endocrinol 1998;157:453–461.
   PubMed Web of Science ®Google Scholar
• Mascanfroni I, Montesinos MM, Susperreguy S, . Control of dendritic cell maturation and function by triiodothyronine. FASEB J 2008;22:1032–1042.
   PubMed Web of Science ®Google Scholar
• Montesinos MM, Alamino VA, Mascanfroni ID, . Dexamethasone counteracts the immunostimulator effects of triiodothyronine (T3) on dendritic cells. Steroids 2012;77:67–76.
   PubMed Web of Science ®Google Scholar
• D’Haese JG, Demir IE, Friess H, . Fractalkine/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential. Expert Opin Ther Targets 2010;14:207–219.
   PubMed Web of Science ®Google Scholar
• D’Haese JG, Friess H, Ceyhan GO. Therapeutic potential of the chemokine-receptor duo fractalkine/CX3CR1: an update. Expert Opin Ther Targets 2012;16:613–618.
   PubMed Web of Science ®Google Scholar
• Desforges NM, Hebron ML, Algarzae NK, . Fractalkine mediates communication between pathogenic proteins and microglia: implications of anti-inflammatory treatments in different stages of neurodegenerative diseases. Int J Alzheimers Dis 2012;2012:345472.
   PubMedGoogle Scholar
• Cotter R, Williams C, Ryan L, . Fractalkine (CX3CL1) and brain inflammation: implications of HIV-1-assciated dementia. J Neurovirol 2002;8:585–598.
   PubMed Web of Science ®Google Scholar
• Liu M, Guo S, Stiles JK. The emerging role of CXCL10 in cancer (review). Oncol Lett 2011;2:583–589.
   PubMed Web of Science ®Google Scholar
• Lin HY, Shih A, Davis FB, . Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. Biochem J 1999;338:427–432.
   PubMed Web of Science ®Google Scholar
• Lin HY, Martino LJ, Wilcox BD, . Potentiation by thyroid hormone of human IFN-gamma-induced HLA-DR expression. J Immunol 1999;161:843–849.
   Web of Science ®Google Scholar
• Rotondi M, Chiavato L. The chemokine system as a therapeutic target in autoimmune thyroid diseases: a focus on the interferon-γ inducible chemokines and their receptor. Curr Pharm Des 2011;17:3202–3216.
   PubMed Web of Science ®Google Scholar
• Shih A, Zhang S, Cao HJ, . Disparate effects of thyroid hormone on actions of epidermal growth factor and transforming growth factor-alpha are mediated by 3’, 5’-cyclic adenosine 5’-monophosphate-dependent protein kinase II. Endocrinology 2004;145:1708–1717.
   PubMed Web of Science ®Google Scholar
• Berasain C, Castillo J, Perugorria MJ, . Inflammation and liver cancer: new molecular links. Ann NY Acad Sci 2009;155:206–221.
   Google Scholar
• Zhang Y, Wang L, Zhang M, . Potential mechanism of interleukin-8 production from lung cancer cells: an involvement of EGF-EGFR-PI3K-Akt-Erk pathway. J Cell Physiol 2012;227:35–43.
   PubMed Web of Science ®Google Scholar
• Glinskii AB, Glinsky GV, Lin HY, . Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac). Cell Cycle 2009;8(21):3554–3562.
   Google Scholar
• Rainger GE, Buckley CD, Simmons DL, . Neurophils sense flow-generated stress and direct their migration through alphavbeta3-integrin. Am J Physiol 1999;276(3 Pt2):H858–H864.
   PubMed Web of Science ®Google Scholar
• Janardhan KS, Appleyard GD, Singh B. Expression of integrin subunits alphav and beta3 in acute lung inflammation. Histochem Cell Biol 2004;121:383–390.
   PubMed Web of Science ®Google Scholar
• Sokalska A, Duleba AJ, Pawelczyk LA. Correlation of the expression of integrin αvβ3 in endometrium and peripheral blood lymphocytes in infertile patients. Reprod Sci 2010;17:487–493.
   PubMed Web of Science ®Google Scholar
• Singh B, Janardhan KS, Kanthan R. Expression of angiostatin, integrin alphavbeta3, and vitronectin in human lungs in sepsis. Exp Lung Res 2005;31:771–782.
   PubMed Web of Science ®Google Scholar
• Hrycek A. Functional characterization of peripheral blood neutrophils in patients with primary hypothyroidism. Foli Biol (Praha) 1993;39:304–310.
   PubMed Web of Science ®Google Scholar
• Marino F, Guasti L, Cosentino M, . Thyroid hormone regulation of cell migration and oxidative metabolism in polymorphonuclear leukocytes: clinical evidence in thyroidectomized subjects on thyroxine replacement therapy. Life Sci 2006;78:1071–1077.
   PubMed Web of Science ®Google Scholar
• Mezosi E, Szabo J, Nagy EV, . Nongenomic effect of thyroid hormone on free-radical production in human polymorphonuclear leukocytes. J Endocrinol 2005;185:121–12913.
   PubMed Web of Science ®Google Scholar
• Glinskii AB, Ma J, Ma S, . Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle 2009;8:3925–3942.
   PubMed Web of Science ®Google Scholar
• Glinskii AB, Ma J, Ma S, . Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders. Cell Cycle 2011;10:3571–3597.
   PubMed Web of Science ®Google Scholar
• Glinsky GV, Glinskii AB, Berezovskaya O. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005;115:1503–1521.
   PubMed Web of Science ®Google Scholar
• Glinsky GV, Higashiyama T, Glinskii AB. Classification of human breast cancer using gene expression profiling as a component of the survival predictor algorithm. Clin Cancer Res 2004;10:2272–2283.
   Google Scholar
• Glinsky GV, Glinskii AB, Stephenson AJ, . Gene expression profiling predicts clinical outcome of prostate cancer. J Clin Invest 2004;113:913–923.
   PubMed Web of Science ®Google Scholar
• Glinsky GV, Krones-Herzig A, Glinskii AB, . Microarray analysis of xenograft-derived cancer cell lines representing multiple experimental models of human prostate cancer. Mol Carcinog 2003;37:209–221.
   Google Scholar