Mendelian and trans-generational inheritance in hypertensive renal disease

References

• Freedman BI. Susceptibility genes for hypertension and renal failure. J Am Soc Nephrol. 2003;14(Suppl 2):S192–4.
   Google Scholar
• Freedman BI, Spray BJ, Tuttle AB, Buckalew VM Jr. The familial risk of end-stage renal disease in African Americans. Am J Kidney Dis. 1993;21:387–93.
   PubMedGoogle Scholar
• Freedman BI, Soucie JM, McClellan WM. Family history of end-stage renal disease among incident dialysis patients. J Am Soc Nephrol. 1997;8:1942–5.
   PubMedGoogle Scholar
• Lei HH, Perneger TV, Klag MJ, Whelton PK, Coresh J. Familial aggregation of renal disease in a population-based case-control study. J Am Soc Nephrol. 1998;9:1270–6.
   PubMedGoogle Scholar
• Gigante B, Rubattu S, Stanzione R, Lombardi A, Baldi A, Baldi F, . Contribution of genetic factors to renal lesions in the stroke-prone spontaneously hypertensive rat. Hypertension. 2003;42:702–6.
   PubMedGoogle Scholar
• Schelling JR, Zarif L, Sehgal A, Iyengar S, Sedor JR. Genetic susceptibility to end-stage renal disease. Curr Opin Nephrol Hypertens. 1999;8:465–72.
   PubMedGoogle Scholar
• DeWan AT, Arnett DK, Atwood LD, Province MA, Lewis CE, Hunt SC, . A genome scan for renal function among hypertensives: the HyperGEN study. Am J Hum Genet. 2001;68:136–44.
   PubMedGoogle Scholar
• Freedman BI, Beck SR, Rich SS, Heiss G, Lewis CE, Turner S, . A genome-wide scan for urinary albumin excretion in hypertensive families. Hypertension. 2003;42:291–6.
   PubMed Web of Science ®Google Scholar
• DeWan AT, Arnett DK, Miller MB, Peacock JM, Atwood LD, Province MA, . Refined mapping of suggestive linkage to renal function in African Americans: the HyperGEN study. Am J Hum Genet. 2002;71:204–5.
   PubMedGoogle Scholar
• Turner ST, Kardia SL, Mosley TH, Rule AD, Boerwinkle E, de Andrade M. Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships. J Am Soc Nephrol. 2006;17:2048–55.
   PubMed Web of Science ®Google Scholar
• Fox CS, Yang Q, Guo CY, Cupples LA, Wilson PW, Levy D, . Genome-wide linkage analysis to urinary microalbuminuria in a community-based sample: the Framingham Heart Study. Kidney Int. 2005;67:70–4.
   PubMedGoogle Scholar
• Hunt SC, Coon H, Hasstedt SJ, Cawthon RM, Camp NJ, Wu LL, . Linkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees. Am J Hypertens. 2004;17:511–5.
   PubMed Web of Science ®Google Scholar
• Anderson CA, Pettersson FH, Barrett JC, Zhuang JJ, Ragoussis J, Cardon LR, . Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms. Am J Hum Genet. 2008;83: 112–9.
   PubMedGoogle Scholar
• Balding DJ. A tutorial on statistical methods for population association studies. Nat Rev Genet. 2006;7:781–91.
   PubMed Web of Science ®Google Scholar
• ; International Consortium for Blood Pressure Genome-Wide Association StudiesEhret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, . Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478:103–9.
   PubMed Web of Science ®Google Scholar
• Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661–78.
   PubMed Web of Science ®Google Scholar
• Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, . Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 2010;42:373–5.
   PubMed Web of Science ®Google Scholar
• Kottgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, . Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009;41:712–7.
   PubMed Web of Science ®Google Scholar
• Kottgen A, Pattaro C, Boger CA, Fuchsberger C, Olden M, Glazer N, . New loci associated with kidney function and chronic kidney disease. Nat Genet. 2010;42:376–84.
   PubMed Web of Science ®Google Scholar
• Pattaro C, De Grandi A, Vitart V, Hayward C, Franke A, Aulchenko YS, . A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet. 2010;11:41.
   PubMed Web of Science ®Google Scholar
• Sheikh-Hamad D. Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol. 2010;298:F248–54.
   PubMedGoogle Scholar
• Wang Y, Huang L, Abdelrahim M, Cai Q, Truong A, Bick R, . Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2. J Leukoc Biol. 2009;86:981–8.
   PubMedGoogle Scholar
• Saemann MD, Weichhart T, Zeyda M, Staffler G, Schunn M, Stuhlmeier KM, . Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism. J. Clin Invest. 2005;115:468–75.
   Google Scholar
• Kottgen A, Hwang SJ, Larson MG, Van Eyk JE, Fu Q, Benjamin EJ, . Uromodulin levels associate with a common UMOD variant and risk for incident CKD. J Am Soc Nephrol. 2010;21:337–44.
   PubMedGoogle Scholar
• Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Gentilini D, . Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet. 2010;6:e1001177.
   PubMed Web of Science ®Google Scholar
• Ikram MK, Sim X, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, . Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010;6:e1001184.
   PubMed Web of Science ®Google Scholar
• Chakraborty R, Weiss KM. Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. Proc Natl Acad Sci U S A. 1988;85: 9119–23.
   PubMed Web of Science ®Google Scholar
• Kao WH, Klag MJ, Meoni LA, Reich D, Berthier-Schaad Y, Li M, . MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet. 2008; 40:1185–92.
   PubMed Web of Science ®Google Scholar
• Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, Bowden DW, . MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat Genet. 2008;40: 1175–84.
   PubMed Web of Science ®Google Scholar
• Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, . Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science. 2010;329:841–5.
   PubMed Web of Science ®Google Scholar
• Pollak MR. Kidney disease and African ancestry. Nat Genet. 2008;40:1145–6.
   PubMedGoogle Scholar
• Seri M, Pecci A, Di Bari F, Cusano R, Savino M, Panza E, . MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness. Medicine. 2003;82:203–15.
   PubMed Web of Science ®Google Scholar
• Ghiggeri GM, Caridi G, Magrini U, Sessa A, Savoia A, Seri M, . Genetics, clinical and pathological features of glomerulonephritis associated with mutations of nonmuscle myosin IIA (Fechtner syndrome). Am J Kidney Dis. 2003;41:95–104.
   PubMedGoogle Scholar
• Johnstone DB, Zhang J, George B, Leon C, Gachet C, Wong H, . Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy. Mol Cell Biol. 2011;31:2162–70.
   PubMed Web of Science ®Google Scholar
• Tzur S, Rosset S, Shemer R, Yudkovsky G, Selig S, Tarekegn A, . Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet. 2010;128:345–50.
   PubMed Web of Science ®Google Scholar
• Waddington CH. The Strategy of the genes. London, UK: Allen and Unwin; 1957.
   Google Scholar
• Russo VEA, Martienssen RA, Riggs AD, editors. Epigenetic mechanisms of gene regulation. Woodbury, NY: Cold Spring Harbor Laboratory Press; 1996.
   Google Scholar
• Allis CD, Jenuwein T, Reinberg D. Overview and concepts. In: Allis CD, Jenuwein T, Reinberg D, editors. Epigenetics. Woodbury, NY: Cold Spring Harbor Laboratory Press; 2007. p. 23–56.
   Google Scholar
• Das R, Hampton DD, Jirtle RL. Imprinting evolution and human health. Mamm Genome. 2009;20:563–72.
   PubMed Web of Science ®Google Scholar
• Moore T, Haig D. Genomic imprinting in mammalian development: a parental tug-of-war. Trends Genet. 1991;7:45–9.
   PubMed Web of Science ®Google Scholar
• Kucharski R, Maleszka J, Foret S, Maleszka R. Nutritional control of reproductive status in honeybees via DNA methylation. Science. 2008;319:1827–30.
   PubMed Web of Science ®Google Scholar
• Sadd BM, Kleinlogel Y, Schmid-Hempel R, Schmid-Hempel P. Trans-generational immune priming in a social insect. Biol Lett. 2005;1:386–8.
   Google Scholar
• Grindstaff JL, Hasselquist D, Nilsson JK, Sandell M, Smith HG, Stjernman M. Transgenerational priming of immunity: maternal exposure to a bacterial antigen enhances offspring humoral immunity. Proc Biol Sci. 2006;273:2551–7.
   PubMed Web of Science ®Google Scholar
• Hasselquist D, Nilsson JA. Maternal transfer of antibodies in vertebrates: trans-generational effects on offspring immunity. Philos Trans R Soc Lond B Biol Sci. 2009;364:51–60.
   PubMed Web of Science ®Google Scholar
• Reid JM, Arcese P, Keller LF, Hasselquist D. Long-term maternal effect on offspring immune response in song sparrows Melospiza melodia. Biol Lett. 2006;2:573–6.
   PubMedGoogle Scholar
• Greeley SA, Katsumata M, Yu L, Eisenbarth GS, Moore DJ, Goodarzi H, . Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat Med. 2002;8:399–402.
   PubMed Web of Science ®Google Scholar
• Yamashita T, Freigang S, Eberle C, Pattison J, Gupta S, Napoli C, . Maternal immunization programs postnatal immune responses and reduces atherosclerosis in offspring. Circ Res. 2006;99:e51–64.
   PubMed Web of Science ®Google Scholar
• Lundin BS, Dahlman-Hoglund A, Pettersson I, Dahlgren UI, Hanson LA, Telemo E. Antibodies given orally in the neonatal period can affect the immune response for two generations: evidence for active maternal influence on the newborn's immune system. Scand J Immunol. 1999;50:651–6.
   PubMedGoogle Scholar
• Matson AP, Thrall RS, Rafti E, Puddington L. Breastmilk from allergic mothers can protect offspring from allergic airway inflammation. Breastfeed Med. 2009;4:167–74.
   PubMed Web of Science ®Google Scholar
• Polte T, Hansen G. Maternal tolerance achieved during pregnancy is transferred to the offspring via breast milk and persistently protects the offspring from allergic asthma. Clin Exp Allergy. 2008;38:1950–8.
   PubMedGoogle Scholar
• Lange H, Kiesch B, Linden I, Otto M, Thierse HJ, Shaw L, . Reversal of the adult IgE high responder phenotype in mice by maternally transferred allergen-specific monoclonal IgG antibodies during a sensitive period in early ontogeny. Eur J Immunol. 2002;32:3133–41.
   PubMedGoogle Scholar
• Lefranc MP, Clement O, Kaas Q, Duprat E, Chastellan P, Coelho I, . IMGT-Choreography for immunogenetics and immunoinformatics. In Silico Biol. 2005;5:45–60.
   PubMedGoogle Scholar
• Teng G, Papavasiliou FN. Immunoglobulin somatic hypermutation. Annu Rev Genet. 2007;41:107–20.
   PubMed Web of Science ®Google Scholar
• Hopkin J, Cookson W. Genetic variation in the beta subunit of the high affinity IgE receptor and atopy and asthma. Clin Exp Allergy. 2006;36:855–7.
   PubMedGoogle Scholar
• Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, . Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 2008;4:e1000166.
   Web of Science ®Google Scholar
• Cierpial MA, McCarty R. Hypertension in SHR rats: contribution of maternal environment. Am J Physiol. 1987; 253(Pt 2):H980–4.
   Google Scholar
• Di Nicolantonio R, Koutsis K, Westcott KT, Wlodek ME. Relative contribution of the prenatal versus postnatal period on development of hypertension and growth rate of the spontaneously hypertensive rat. Clin Exp Pharmacol Physiol. 2006;33:9–16.
   PubMed Web of Science ®Google Scholar
• Lee JY, Azar SH. Wistar-Kyoto and spontaneously hypertensive rat blood pressure after embryo transfer into different wombs and cross-suckling. Exp Biol Med (Maywood). 2010; 235:1375–84.
   PubMed Web of Science ®Google Scholar
• Herring SM, Gokul N, Monita M, Bell R, Boerwinkle E, Wenderfer SE, . Immunoglobulin locus associates with serum IgG levels and albuminuria. J Am Soc Nephrol. 2011; 22:881–9.
   PubMedGoogle Scholar
• Oxelius VA. Immunoglobulin constant heavy G subclass chain genes in asthma and allergy. Immunol Res. 2008;40:179–91.
   PubMed Web of Science ®Google Scholar
• Puttick AH, Briggs DC, Welsh KI, Williamson EA, Jacoby RK, Jones VE. Genes associated with rheumatoid arthritis and mild inflammatory arthritis. II. Association of HLA with complement C3 and immunoglobulin Gm allotypes. Ann Rheum Dis. 1990;49:225–8.
   PubMedGoogle Scholar
• Schernthaner G, Mayr WR. Immunoglobulin allotype markers and HLA DR genes in type I diabetes mellitus. Metabolism. 1984;33:833–6.
   PubMedGoogle Scholar
• Field LL. Non-HLA region genes in insulin dependent diabetes mellitus. Baillieres Clin Endocrinol Metab. 1991;5: 413–38.
   PubMedGoogle Scholar
• Field LL, Stephure DK, McArthur RG. Interaction between T cell receptor beta chain and immunoglobulin heavy chain region genes in susceptibility to insulin-dependent diabetes mellitus. Am J Hum Genet. 1991;49:627–34.
   PubMedGoogle Scholar
• Pandey JP. Genomewide association studies and assessment of risk of disease. N Engl J Med. 2010;363:2076–7; author reply 7.
   PubMedGoogle Scholar