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Original Article

The changing face of sympathetic overactivity in hypertension

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Pages 365-370 | Published online: 08 Jul 2009

References

  • Facchini F S, Stoohs R A, Reaven G M. Enhanced sympathetic nervous system activity. The link between insulin resistance, hyperinsulinemia, and heart rate. Am J Hypertens 1996; 9: 1013–7
  • Julius S, Li Y, Brant D, Krause L, Buda A. Neurogenic pressor episodes fail to cause hypertension, but do induce cardiac hypertrophy. Hypertension 1989; 13: 422–9
  • Julius S, Jamerson K. Sympathetics, insulin resistance and coronary risk in hypertension: the ‘chicken-and-egg’ question. J Hypertens 1994; 12: 495–502
  • Julius S, Krause L, Schork N, Mejia A, Jones K, van de Ven C, et al. Hyperkinetic borderline hypertension in Tecumseh, Michigan. J Hypertens 1991; 9: 77–84
  • Esler M, Julius S, Zweifler A, Randall O, Harburg E, Gardiner H, et al. Mild high-renin essential hypertension: neurogenic human hypertension. N Engl J Med 1977; 296: 405–11
  • Young E A, Nesse R M, Weder A, Julius S. Anxiety and cardiovascular reactivity in the Tecumseh population. J Hypertens 1998; 16: 1727–33
  • Palatini P, Julius S. Heart rate and the cardiovascular risk. J Hypertens 1997; 15: 1–15
  • Devereux R B, Pickering T G, Harsfield G A, Kleinert H D, Denby L, Clark L, et al. Left ventricular hypertrophy in patients with hypertension: importance of blood pressure response to regularly recurring stress. Circulation 1983; 68: 470–6
  • Widimsky J, Fejfarova M H, Fejfar Z. Changes of cardiac output in hypertensive disease. Cardiologia 1957; 31: 381–9
  • Lund-Johansen P. Hemodynamic alterations in early essential hypertension: recent advances. Mild hypertension: recent advances, F Gross, Strassen. Raven Press, New York, NY 1983; 237–49
  • Eich R H, Peters R J, Cuddy R P, Smulyan H, Lyons R H. The hemodynamics in labile hypertension. Am Heart J 1962; 63: 188–95
  • Safar M E, Weiss Y A, Levenson J A, London G M, Milliez P L. Hemodynamic study of 85 patients with borderline hypertension. Am J Cardiol 1973; 31: 315–9
  • Messerli F H, Frochlich E D, Suarez D H, Reisin E, Dreslinski G R, Dunn F G, et al. Borderline hypertension: relationship between age, hemodynamics and circulating catecholamines. Circulation 1981; 64: 760–4
  • Eich R H, Cuddy R P, Smulyan H, Lyons R H. Hemodynamics in labile hypertension: a follow-up study. Circulation 1966; 34: 299–307
  • Julius R, Pascual A, London R. Role of sympathetic inhibition in the hyperkinetic type of borderline hypertension. Circulation 1971; 44: 413–8
  • Julius S, Conway J. Hemodynamic studies in patients with borderline blood pressure elevation. Circulation 1968; 38: 282–8
  • Anderson E A, Sinkey C A, Lawton W J, Mark A L. Elevated sympathetic nerve activity in borderline hypertensive humans: evidence from direct intraneural recordings. Hypertension 1989; 14: 177–83
  • Esler M, Jennings G, Lambert G. Noradrenaline release and the pathophysiology of primary human hypertension. Am J Hypertens 1989; 2((3 Pt 2))140s–46s
  • Guzzetti S, Piccaluga E, Casati R, Cerrutti S, Lombardi F, Pagani M, et al. Sympathetic predominance in essential hypertension. A study employing spectral analysis of heart rate variability. J Hypertens 1988; 6: 711–7
  • Bohm R, Van Baak M, Van Hooff M, Moy J, Rahn K H. Salivary flow in borderline hypertension. Klin Wochenschr 1985; 63(Suppl 3)154–6
  • Kjeldsen S E, Gjesdal K, Eide I, Aakesson I, Amundsen R, Foss O P, et al. Increased beta-thromboglobulin in essential hypertension: interactions between arterial plasma adrenaline, platelet function and blood lipids. Acta Med Scand 1983; 213: 369–73
  • Tibblin G, Bergrentz S -E, Bjure J, Wilhelmsen L. Hematocrit, plasma protein, plasma volume, and viscosity in early hypertensive disease. Am Heart J 1966; 72: 165–76
  • Geisbock W. The meaning of blood pressure management for practice (in German). Dtsch Arch Klin Med 1905; 83: 363–74
  • Julius R, Pascual A, Reilly K, London R. Abnormalities of plasma volume in borderline hypertension. Arch Int Med 1971; 127: 116–9
  • Letcher R L, Chien S, Pickering T G, Laragh J H. Elevated blood viscosity in patients with borderline essential hypertension. Hypertension 1983; 5: 757–62
  • Cohn J N. Relationship of plasma volume changes to resistance and capacitance vessel effects of sympathomimetic amines and angiotensin in man. Clin Sci 1966; 30: 267–78
  • Julius R, Pascual A, Abbrecht P, London R. Effect of beta-adrenergic blockade on plasma volume in human subjects. Proc Soc Exp Biol Med 1972; 140: 982–5
  • Smith S, Julius S, Jamerson K, Amerena J, Schork N. Hematocrit levels and physiologic factors in relationship to cardiovascular risk in Tecumseh, Michigan. Hypertension 1994; 12: 455–62
  • Guyton A C, Coleman T G. Quantitative analysis of the pathophysiology of hypertension. Circ Re5 1969; 24((5 SUPPI))1–19
  • Pollare T, Lithell H, Morlin C, Prantare H, Hvarfner A, Ljunghall S. Metabolic effects of diltiazem and atenolol. Results from a randomized, double-blind study with parallel groups. J Hypertens 1989; 7: 551–9
  • Kjeldsen S E, Moan A, Petrin J, Weder A, Julius S. Effects of increased arterial epinephrine on insulin, glucose and phosphate. Blood Pressure 1996; 5: 25–31
  • Folkow B. Physiological aspects of primary hypertension. Physiol Rev 1982; 62: 347–503
  • Egan B, Panis R, Hinderliter A, Schork N, Julius S. Mechanism of increased alpha-adrenergic vasoconstriction in human essential hypertension. J Clin Invest 1987; 80: 812–7
  • Hart M N, Heistad D D, Brody M J. Effect of chronic hypertension and sympathetic denervation on wall/lumen ratio of cerebral vessels. Hypertension 1980; 2: 419–28
  • Bevan R D, Tsuru H, Bevan J H. Cerebral artery mass in the rabbit is reduced by chronic sympathetic denervation. Stroke 1983; 14: 393–6
  • MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, et al. Blood pressure, stroke, and coronary heart disease. Part I, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990; 335: 765–74
  • Collins R, Peto R, MacMahon S, Herbert P, Fiebach N H, Eberlein K A, et al. Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reduction in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 1990; 335: 827–38
  • Julius S, Jamerson K, Mejia A, Krause L, Schork N, Jones K. The association of borderline hypertension with target organ changes and higher coronary risk. Tecumseh Blood Pressure Study. JAMA 1990; 264: 354–8
  • Keys A, Taylor H L, Blackburn H. Mortality and coronary heart disease among men- studies for 23 years. Arch Int Med 1971; 128: 201–14
  • Pyörälä K, Savolainen E, Kaukola S, Haapakoski J. Plasma insulin as a coronary heart disease risk factor: relationship to the other risk factors and predictive value during 9 1/2 year follow-up of the Helsinki Policemen Study. Acta Med Stand Suppl 1985; 701: 38–52
  • Welborn T A, Wearne K. Coronary heart incidence and cardiovascular mortality in Busselton with reference to glucose and insulin concentration. Diabetes Care 1979; 2: 154–60
  • Ducimetiere P, Eschwege E, Papoz L, Richard J L, Claude J R, Rosselin G. Relationship of plasma insulin levels to the incidence of myocardial infarction and coronary heart disease mortality in a middle-aged population. Diabetologia 1980; 19: 205–210
  • Julius S, Gudbrandsson T, Jamerson K, Shahab S T, Andersson O. Hypothesis. The hemodynamic link between insulin resistance and hypertension. J Hypertens 1991; 9: 983–6
  • Julius S, Gudbrandsson T, Jamerson K, Andersson O. The interconnection between sympathetics, microcirculation, and insulin resistance in hypertension. Blood Pressure 1992; 1: 9–19
  • Johlin-Danfelt A, Frisk-Holmberg F, Karlsson J, Tesch P. Central and peripheral circulation in relation to muscle-fiber composition in normo- and hypertensive men. Clin Sci 1979; 56: 335–40
  • Jamerson K, Julius S, Gudbrandsson T, Andersson O, Brant D O. Reflex sympathetic activation induces acute insulin resistance in the human forearm. Hypertension 1993; 21: 618–23
  • Pollare T, Lithell H, Selinus L, Berne C. Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension. Diabetologia 1988; 31: 415–20
  • Krotkiewski M, Bylund-Fallenius A -C, Holm J, Bjorntorp P, Grimby G, Mandroukas K. Relationship between muscle morphology and metabolism in obese women: the effects of long-term physical training. Eur J Clin Invest 1983; 13: 5–12
  • Salonen J T, Lakka T A, Lakka H M, Valkonen V P, Everson S A, Kaplan G A. Hyperinsulinemia is associated with the incidence of hypertension and dyslipidemia in middle-aged men. Diabetes 1998; 47: 270–5
  • Donahue R P, Bean J A, DeCarlo R, Goldberg R B, Prineas R J. Does insulin resistance unite the separate components of the insulin resistance syndrome? Evidence from the Miami Community Health Study. Arterioscler Thromb Bid 1997; 17: 2413–7
  • Pyörälä M, Miettinen H, Laakso M, Pyörälä K. Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22–year follow-up results of the Helsinki Policemen Study. Circulation 1998; 98: 398–404
  • Landsberg L. Diet, obesity and hypertension: a hypothesis involving insulin, the sympathetic nervous system and adaptive thermogenesis. Q J Med 1986; 61: 1081–90
  • Grassi G, Seravalle G, Colombo M, Bolla G, Cattaneo B, Cavagnini F, et al. Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans. Circulation 1998; 97: 2037–42
  • Ferrannini E, Buzzigoli G, Bonnadonna, Giorico M A, Oleggini M, Gradiadei L, et al. Insulin resistance in essential hypertension. N Engl J Med 1987; 317: 350–7
  • Julius S, Valentini M, Palatini P. Overweight and hypertension. A 2-way street. Hypertension 2000; 35: 807–13

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