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Editorial Article

The future of fluoroquinolones

Pages 585-587 | Published online: 08 Jul 2009

References

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  • Schmitz F-J, Fluit A, Brisse S, Verhoef J, Koher K, Milatovic D. Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates. FEMS Immunol Med Microbiol 1999; 26: 281–7
  • Zhao X, Xu C, Domagala J, Drlica K. DNA topoisomerase targets of the fluoroquinolones: a strategy for avoiding bacterial resistance. Proc Natl Acad Sci USA 1997; 94: 13991–6
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  • Sindelar G, Zhao X, Liew A, Dong Y, Zhou J, Domagala J. Mutant prevention concentration (MFC) as a measure of fluoroquinolone potency against mycobacteria. Antimicrob Agents Chemother, (in press)
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  • Blondeau J, Zhao X, Hansen G, Drlica K. Mutant prevention concentration (MFC) for fluoroquinolones with clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother, (in press)
  • Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. Clin Infect Dis, (in press)
  • Zhou J-F, Dong Y, Zhao X, Lee S, Amin A, Ramaswamy S. Selection of antibiotic resistance: allelic diversity among fluoroquinolone-resistant mutations. J Inf Dis 2000; 182: 517–25
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  • Chen D K, McGeer A, DeAzavedo J C, Low DE. Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada. N Engl J Med 1999; 341: 233–9

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