The Role of Transcription Factors in Erythroid Development

References

• Tjian R, Maniatis T. Transcriptional activation: a complex puzzle with few easy pieces. Cell 1994; 77: 5–8
   PubMed Web of Science ®Google Scholar
• Ness S A, Engel J D. Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation. Curr Opin Genet Dev 1994; 4: 718–24
   PubMedGoogle Scholar
• Felsenfeld G. Chromatin as an essential part of the transcriptional mechanism. Nature 1992; 355: 219–24
   PubMed Web of Science ®Google Scholar
• Schmeichel K L, Beckerle N IC. The LIM domain is a modular protein-binding interface. Cell 1994; 79: 211–9
   PubMedGoogle Scholar
• Stamatoyannopoulos G, Neinhuis A W. Hemoglobin switching. The Molecular Basis of Blood Diseases2nd edn., G Stamatoyannopoulos, A W Nienhuis, P Majerus, H Varmus. WB Saunders Co, New York 1994; 107–55
   Google Scholar
• Engel J D. Developmental regulation of human β-globin gene transcription: a switch of loyalties. Trends Genet 1993; 9: 304–9
   PubMedGoogle Scholar
• Forrester W C, Takegawa S, Papayannopoulou T, Stammatoyannopoulos G, Groudine M. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. Nucleic Acids Res 1987; 15: 10159–77
   PubMed Web of Science ®Google Scholar
• Grosveld F, van Assendelft G B, Greaves D R, Kollias G. Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 1987; 51: 975–85
   PubMed Web of Science ®Google Scholar
• Thomas K R, Capecchi M R. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51: 503–12
   PubMed Web of Science ®Google Scholar
• Yamamoto M, Ko L J, Leonard M W, Beug H, Orkin S H, Engel J D. Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev 1990; 4: 1650–62
   PubMed Web of Science ®Google Scholar
• Ko L J, Engel J D. DNA-binding specificities of the GATA transcription factor family. Mol Cell Biol 1993; 13: 4011–22
   PubMed Web of Science ®Google Scholar
• Merika M, Orkin S H. DNA-binding specificity of GATA family transcription factors. Mol Cell Biol 1993; 13: 3999–4010
   PubMed Web of Science ®Google Scholar
• Tsai S-F, Martin D IK, Zon L I, ĎAndrea A D, Wong G GSH, Orkin S H. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature 1989; 339: 446–51
   PubMed Web of Science ®Google Scholar
• Evans T, Felsenfeld G. The erythroid-specific transcription factor Eryf1: a new finger protein. Cell 1989; 58: 877–85
   PubMed Web of Science ®Google Scholar
• Romeo P-H, Prandini M-H, Joulin V, et al. Megakaryocyte and erythrocytic lineages share specific transcription factors. Nature 1990; 344: 447–9
   PubMed Web of Science ®Google Scholar
• Martin D IK, Zon L I, Mutter G, Orkin S H. Expression of an erythroid transcription factor in megakaryocyte and mast cell lineages. Nature 1990; 344: 444–7
   PubMed Web of Science ®Google Scholar
• Ito E, Toki T, Ishihara H, et al. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 1993; 362: 466–9
   PubMed Web of Science ®Google Scholar
• Berry M, Grosveld F, Dillon N. A single point mutation is the cause of the Greek form of hereditary persistence of fetal hemoglobin. Nature 1992; 358: 499–502
   PubMed Web of Science ®Google Scholar
• Raich N, Clegg C H, Grofti J, Romeo P-H, Stamatoyannopoulos G. GATA1 and YY1 are developmental repressors of the human -globin gene. EMBO J 1995; 14: 801–9
   PubMed Web of Science ®Google Scholar
• Merika M, Orkin S H. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Kruppel family proteins Sp1 and EKLF. Mol Cell 1995; 15: 2437–47
   Google Scholar
• Pevny L, Simon M C, Robertson E, et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 1991; 349: 257–60
   PubMed Web of Science ®Google Scholar
• Simon M C, Pevny L, Wiles M V, Keller G, Costantini F, Orkin S H. Rescue of erythroid development in gene targeted GATA-1-mouse embryonic stem cells. Nat Genet 1992; 1: 92–8
   PubMed Web of Science ®Google Scholar
• Zon L I, Youssoufian H, Mather C, Lodish H F, Orkin S H. Activation of the erythroprotein receptor promoter by transcription factor GATA-1. Proc Natl Acad Sci USA 1991; 88: 10638–41
   PubMed Web of Science ®Google Scholar
• Dorfman D M, Wilson D B, Bruns G AP, Orkin S H. Human transcription factor GATA-2; evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J Biol Chem 1992; 267: 1279–85
   PubMed Web of Science ®Google Scholar
• Nagai T, Harigae H, Ishihara H, et al. Transcription factor GATA-2 is expressed in erythroid, early myeloid and CD34+ human leukemia-derived cell lines. Blood 1994; 84: 1074–84
   PubMed Web of Science ®Google Scholar
• Tsai F-Y, Keller G, Kuo F C, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994; 371: 221–6
   PubMed Web of Science ®Google Scholar
• Briegel K, Lim K-C, Plank C, Beug H, Engel J D, Zenke M. Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. Genes Dev 1993; 7: 1097–109
   PubMedGoogle Scholar
• Weiss M J, Keller G, Orkin S H. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1-embryonic stem cells. Genes Dev 1994; 8: 1184–97
   PubMed Web of Science ®Google Scholar
• Zon L I, Gurish M F, Stevens R L, et al. GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. J Biol Chem 1991; 266: 22948–53
   PubMedGoogle Scholar
• Leonard M W, Lim K-C, Engel J D. Expression of the GATA transcription factor family during early erythroid development and differentiation. Development 1993; 119: 519–31
   PubMedGoogle Scholar
• Pandolfi P P, Roth M E, Karis A, et al. Targeted disruption of the GATA-3 gene causes severe abnormalities of the CNS, haemorrage and altered haematopoiesis. Nat Genet 1995; 11: 40–4
   PubMedGoogle Scholar
• Andrews N C, Erjument-Bromage H, Davidson M B, Tempst P, Orkin S H. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature 1993; 362: 722–8
   PubMed Web of Science ®Google Scholar
• Mignotte V, Eleouet J F, Raich N, Romeo P-H. Cis- and frans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene. Proc Natl Acad Sci USA 1989; 86: 6548–52
   PubMed Web of Science ®Google Scholar
• Andrews N C, Kotkow K J, Ney P A, Erdjument-Bromage H, Tempst P, Orkin S H. The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene. Proc Natl Acad Sci USA 1993; 90: 11488–92
   PubMed Web of Science ®Google Scholar
• Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 1994; 367: 568–72
   PubMed Web of Science ®Google Scholar
• Engel J D. Meticulous AP-1 factors. Nature 1994; 367: 516–7
   Google Scholar
• Stamatoyannopoulos J A, Goodwin A, Joyce T, Lowrey C H. NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region. EMBO J 1995; 14: 106–16
   PubMed Web of Science ®Google Scholar
• Miller I J, Bieker J J. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the kruppel family of nuclear proteins. Mol Cell Biol 1993; 13: 2776–86
   PubMed Web of Science ®Google Scholar
• Bieker J J, Southwood C M. The erythroid kruppel-like factor transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter. Mol Cell Biol 1995; 15: 852–60
   PubMedGoogle Scholar
• Feng W C, Southwoods C W, Bieker J J. Analyses of β-thalassemia mutant DNA interactions with erythroid kruppel-like factor, an erythroid cell-specifc transcription factor. J Biol Chem 1994; 269: 1–8
   Google Scholar
• Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F. Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature 1995; 375: 316–8
   PubMed Web of Science ®Google Scholar
• Perkins A C, Sharpe A H, Orkin S H. Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature 1995; 375: 318–22
   PubMed Web of Science ®Google Scholar
• Mouthon M-A, Bernard O, Mitjavila M T, Romeo P-H, Vainchenker W, Mathieu-Mauhui D. Expression of tal-1 and GATA-binding proteins during human hematopoiesis. Blood 1993; 81: 647–55
   PubMed Web of Science ®Google Scholar
• Bresnick E H, Felsenfeld G. Evidence that the transcription factor USF is a component of the human β-globin locus control region heteromeric protein complex. J Biol Chem 1993; 268: 18824–34
   PubMedGoogle Scholar
• Apian P D, Nakahara K, Orkin S H, Kirsch I R. The SCL gene product: a positive regulator of erythroid differentiation. EMBO J 1992; 11: 4073–81
   PubMedGoogle Scholar
• Shivdasani R A, Mayer E L, Orkin S H. Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature 1995; 373: 432–4
   PubMed Web of Science ®Google Scholar
• Valge-Archer V E, Osada H, Warren A J, et al. The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. Proc Natl Acad Sci 1994; 91: 8617–21
   PubMedGoogle Scholar
• Foroni L, Boehm T, White L, et al. The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. J Mol Biol 1992; 226: 747–61
   PubMed Web of Science ®Google Scholar
• Crossley M, Merika M, Orkin S H. Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains. Mol Cell Biol 1995; 15: 2448–56
   PubMedGoogle Scholar
• Warren A J, Colledge W H, Carlton M BL, Evans M J, Smith A JH, Rabbitts T H. The oncogenic cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development. Cell 1994; 78: 45–57
   PubMed Web of Science ®Google Scholar
• Jane S M, Nienhuis A W, Cunningham J M. Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. EMBO J 1995; 14: 97–105
   PubMed Web of Science ®Google Scholar
• Gallarda J L, Foley K P, Yang Z, Engel J D. The β-globin stage selector element factor is erythroid-specific promoter/enhancer binding protein NF-E4. Genes Dev 1989; 3: 1845–59
   PubMed Web of Science ®Google Scholar
• Yang Z, Engel J D. Biochemical characterization of the developmental stage- and tissue-specific erythroid transcription factor, NF-E4. J Biol Chem 1994; 269: 10079–87
   PubMed Web of Science ®Google Scholar
• Klempnauer K-H, Gonda T D, Bishop J M. Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell 1982; 31: 453–63
   PubMed Web of Science ®Google Scholar
• Klempnauer K-H, Arnold H, Biedenkapp H. Activation of transcription by v-myb: evidence for two different mechanisms. Genes Dev 1989; 3: 1582–9
   PubMedGoogle Scholar
• Clarke M F, Kukowska-Latallo J F, Westin E, Smith M, Prochownik E U. Constitutive expression of a c-myb cDNA blocks friend murine erythroleukemia cell differentiation. Mol Cell Biol 1988; 8: 884–92
   PubMed Web of Science ®Google Scholar
• Mucenski M L, McLain K, Kier A B, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991; 65: 677–89
   PubMed Web of Science ®Google Scholar
• Todokoro K, Watson R J, Higo H, et al. Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation. Proc Nat Acad Sci USA 1988; 85: 8900–4
   PubMed Web of Science ®Google Scholar
• Scott E W, Simon M C, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994; 265: 1573–7
   PubMed Web of Science ®Google Scholar
• Strubin M, Newell J W, Matthias P. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 1995; 80: 497–506
   PubMed Web of Science ®Google Scholar