Associations between the oxytocin receptor gene (OXTR) and “mind-reading” in humans—An exploratory study

References

• Domes G, Heinrichs M, Michel A, Berger C, Herpertz SC. Oxytocin improves “mind-reading” in humans. Biol Psychiatry2007;61:731–3.
   PubMed Web of Science ®Google Scholar
• Guastella AJ, Einfeld SL, Gray KM, Rinehart NJ, Tonge BJ, Lambert TJ, . Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol Psychiatry2009;65:728–31.
   PubMed Web of Science ®Google Scholar
• Wu S, Jia M, Ruan Y, Liu J, Guo Y, Shuang M, . Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry2005;58:74–7.
   PubMed Web of Science ®Google Scholar
• Pickles A, Bolton P, Macdonald H, Bailey A, Le Couteur A, Sim CH, . Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: A twin and family history study of autism. Am J Hum Genet1995;57: 717–26.
   PubMed Web of Science ®Google Scholar
• Lucht MJ, Barnow S, Sonnenfeld C, Rosenberger A, Grabe HJ, Schroeder W, . Associations between the oxytocin receptor gene (OXTR) and affect, loneliness and intelligence in normal subjects. Prog Neuropsychopharmacol Biol Psychiatry2009;33:860–6.
   PubMed Web of Science ®Google Scholar
• Jacob S, Brune CW, Carter CS, Leventhal BL, Lord C, Cook EH, Jr.Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism. Neurosci Lett2007;417:6–9.
   PubMed Web of Science ®Google Scholar
• Yrigollen CM, Han SS, Kochetkova A, Babitz T, Chang JT, Volkmar FR, . Genes controlling affiliative behavior as candidate genes for autism. Biol Psychiatry2008;63:911–6.
   PubMed Web of Science ®Google Scholar
• Lerer E, Levi S, Salomon S, Darvasi A, Yirmiya N, Ebstein RP. Association between the oxytocin receptor (OXTR) gene and autism: Relationship to Vineland Adaptive Behavior Scales and cognition. Mol Psychiatry2007.
   Web of Science ®Google Scholar
• Israel S, Lerer E, Shalev I, Uzefovsky F, Riebold M, Laiba E, . The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task. PLoS One2009;4:e5535.
   PubMed Web of Science ®Google Scholar
• Apicella CL, Cesarini D, Johannesson M, Dawes CT, Lichtenstein P, Wallace B, . No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences. PLoS One2010;5:e11153.
   PubMed Web of Science ®Google Scholar
• Costa B, Pini S, Gabelloni P, Abelli M, Lari L, Cardini A, . Oxytocin receptor polymorphisms and adult attachment style in patients with depression. Psychoneuroendocrinology2009;34: 1506–14.
   PubMed Web of Science ®Google Scholar
• Gillath O, Shaver PR, Baek JM, Chun DS. Genetic correlates of adult attachment style. Pers Soc Psychol Bull2008;34:1396–405.
   PubMed Web of Science ®Google Scholar
• Uhl-Bronner S, Waltisperger E, Martinez-Lorenzana G, Condes Lara M, Freund-Mercier MJ. Sexually dimorphic expression of oxytocin binding sites in forebrain and spinal cord of the rat. Neuroscience2005;135:147–54.
   PubMed Web of Science ®Google Scholar
• Carter CS. Sex differences in oxytocin and vasopressin: Implications for autism spectrum disorders?Behav Brain Res2007;176:170–86.
   PubMed Web of Science ®Google Scholar
• White S, Hill E, Winston J, Frith U. An islet of social ability in Asperger Syndrome: Judging social attributes from faces. Brain Cogn2006;61:69–77.
   PubMed Web of Science ®Google Scholar
• Grabe H, Lange M, Wolff B, Voelzke H, Lucht M, Freyberger HJ, . Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Mol Psychiatry2005;10:220–4.
   PubMed Web of Science ®Google Scholar
• John U, Greiner B, Hensel E, Lüdemann J, Piek M, Sauer S, . Study of health in Pomerania (SHIP): A health examination survey in an east German region: Objectives and design. Sozial Präventivmed2001;46:186–94.
   PubMedGoogle Scholar
• Lucht M, Barnow S, Schroeder W, Grabe HJ, Rosskopf D, Brummer C, . Alcohol consumption is associated with an interaction between DRD2 exon 8 A/A genotype and self-directedness in males. Neuropsychobiology2007;56:24–31.
   PubMed Web of Science ®Google Scholar
• Tewes U. Hamburg-Wechsler-Intelligenztest für Kinder 3. Revision. Bern: Huber; 1985.
   Google Scholar
• Tewes U. HAWIE-R Hamburg-Wechsler-Intelligenztest für Erwachsene—Revision; 1991.
   Google Scholar
• Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I. The “Reading the Mind in the Eyes” Test revised version: A study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry2001;42:241–51.
   PubMed Web of Science ®Google Scholar
• Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res1988;16:1215.
   PubMed Web of Science ®Google Scholar
• Freeman B, Powell J, Ball D, Hill L, Craig I, Plomin R. DNA by mail: An inexpensive and noninvasive method for collecting DNA samples from widely dispersed populations. Behav Genet1997;27:251–7.
   PubMed Web of Science ®Google Scholar
• Chakrabarti B, Dudbridge F, Kent L, Wheelwright S, Hill- Cawthorne G, Allison C, . Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Autism Res2009;2: 157–77.
   PubMed Web of Science ®Google Scholar
• Kelemenova S, Schmidtova E, Ficek A, Celec P, Kubranska A, Ostatnikova D. Polymorphisms of candidate genes in Slovak autistic patients. Psychiatr Genet2010;20:137–9.
   PubMed Web of Science ®Google Scholar
• Algovik M, Kivinen K, Peterson H, Westgren M, Kere J. Genetic evidence of multiple loci in dystocia—Difficult labour. BMC Med Genet2010;11:105.
   PubMed Web of Science ®Google Scholar
• Gimpl G, Fahrenholz F. The oxytocin receptor system: Structure, function, and regulation. Physiol Rev2001;81:629–83.
   PubMed Web of Science ®Google Scholar
• Chamary JV, Parmley JL, Hurst LD. Hearing silence: Non-neutral evolution at synonymous sites in mammals. Nat Rev Genet2006;7:98–108.
   PubMed Web of Science ®Google Scholar
• Hershberg R, Petrov DA. Selection on codon bias. Annu Rev Genet2008;42:287–99.
   PubMed Web of Science ®Google Scholar
• Lewin C, Herlitz A. Sex differences in face recognition—Women’s faces make the difference. Brain Cogn2002;50:121–8.
   PubMed Web of Science ®Google Scholar
• Sun Y, Gao X, Han S. Sex differences in face gender recognition: An event-related potential study. Brain Res2010.
   Google Scholar
• Domes G, Lischke A, Berger C, Grossmann A, Hauenstein K, Heinrichs M, . Effects of intranasal oxytocin on emotional face processing in women. Psychoneuroendocrinology2010;35: 83–93.
   PubMed Web of Science ®Google Scholar
• Tost H, Kolachana B, Hakimi S, Lemaitre H, Verchinski BA, Mattay VS, . A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic–limbic structure and function. Proc Natl Acad Sci U S A2010;107:13936–41.
   PubMed Web of Science ®Google Scholar
• van Honk J, Schutter DJ, Bos PA, Kruijt AW, Lentjes EG, Baron-Cohen S. Testosterone administration impairs cognitive empathy in women depending on second-to-fourth digit ratio. Proc Natl Acad Sci U S A2011;108:3448–52.
   PubMed Web of Science ®Google Scholar
• Thompson RR, George K, Walton JC, Orr SP, Benson J. Sex- specific influences of vasopressin on human social communication. Proc Natl Acad Sci U S A2006;103:7889–94.
   PubMed Web of Science ®Google Scholar
• Kogan A, Saslow LR, Impett EA, Oveis C, Keltner D, Rodrigues Saturn S. Thin-slicing study of the oxytocin receptor (OXTR) gene and the evaluation and expression of the prosocial disposition. Proc Natl Acad Sci U S A2011;108:19189–92.
   PubMed Web of Science ®Google Scholar
• Park J, Willmott M, Vetuz G, Toye C, Kirley A, Hawi Z, . Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD. Prog Neuropsychopharmacol Biol Psychiatry2010;34:697–702.
   PubMed Web of Science ®Google Scholar
• Rodrigues SM, Saslow LR, Garcia N, John OP, Keltner D. Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. Proc Natl Acad Sci U S A2009;106:21437–41.
   PubMed Web of Science ®Google Scholar
• Lerer E, Levi S, Salomon S, Darvasi A, Yirmiya N, Ebstein RP. Association between the oxytocin receptor (OXTR) gene and autism: Relationship to Vineland Adaptive Behavior Scales and cognition. Mol Psychiatry2008;13:980–8.
   PubMed Web of Science ®Google Scholar
• Kim HS, Sherman DK, Sasaki JY, Xu J, Chu TQ, Ryu C, . Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking. Proc Natl Acad Sci U S A2010;107:15717–21.
   PubMed Web of Science ®Google Scholar
• Lin PI, Vance JM, Pericak-Vance MA, Martin ER. No gene is an island: The flip-flop phenomenon. Am J Hum Genet2007;80: 531–8.
   PubMed Web of Science ®Google Scholar
• Mizumoto Y, Kimura T, Ivell R. A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppression. Mol Cell Endocrinol1997;135:129–38.
   PubMed Web of Science ®Google Scholar
• Lander ES, Schork NJ. Genetic dissection of complex traits. Science1994;265:2037–48.
   PubMed Web of Science ®Google Scholar
• Rajkumar AP, Yovan S, Raveendran AL, Russell PS. Can only intelligent children do mind reading: The relationship between intelligence and theory of mind in 8 to 11 years old. Behav Brain Funct2008;4:51.
   PubMed Web of Science ®Google Scholar