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Original Article

What do Stereoisomers of Antidepressant Drugs Indicate About the Topography of the Serotonin Uptake Area?

Pages 91-94 | Published online: 12 Jul 2009

References

  • Ross S B. Antidepressant drugs: (Z)- and (E)-isomers. Handbook of Stereoisomers. Drugs in Psychopharmacology, DF Smith. CRC press, Boca Raton, Fl. 1984; 241–53
  • Nickolson VJ, Pinder RM. Antidepressant drugs: chiral stereoisomers. Handbook of Stereoisomers. Drugs in Psychopharmacology, DF Smith. CRC Press, Boca Raton, Fl. 1984; 215–40
  • Smith D F. Stereopsychopharmacology: Past, present and future. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1984a; 8: 327–50
  • Smith D F. Introduction to stereopsychopharmacology. Handbook of Stereoisomers. Drugs in Psychopharmacology, DF Smith. CRC Press, Boca Raton, Fl. 1984b; 11–30
  • Carlsson A, Corrodi H, Fuxe K, Hokfelt T. Effects of antidepressant drugs in the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-alpha-ethyl-meta-tyramine. European J Pharmacol 1969; 5: 357–66
  • Ross SB, Renyi AL. Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue. European J Pharmacol 1969; 7: 270–7
  • Lapin IP, Oxenkrug GF. Intensification of the central serotoninergic process as a possible determinant of the thymoleptic effect. Lancet 1969; i(6)132
  • Tuomisto J. Some structural features of amine uptake mechanisms. Advances in Pharmacology and Therapeutics, Neurotransmitters, P Simon. Pergamon Press, Oxford and New York 1978; Vol. 2: 231–48
  • Lindberg UH, Thorberg SO, Bengtsson S, Renyi AL, Ross SB, Ogren S-O. Inhibitors of neuronal monoamine uptake. 2. Selective inhibition of 5-hydroxytryptamine uptake by alpha-amino acid esters of phenethyl alcohols. J Med Chem 1978; 5: 448–56
  • Smith D F. The stereoselectivity of serotonin uptake in brain tissue and blood platelets: The topography of the serotonin uptake area. Neurosci. Biobehav. Rev. 1986; 10, (in press)
  • Ross SB, Aperia B, Beck-Friis J, Jansa S, Wetterberg L, Åberg A. Inhibition of 5-hydroxytryptamine uptake in human platelets by antidepressant agents in vivo. Psychopharmacology 1980; 67: 1–7

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