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Original Article

Alzheimer's disease neurofibrillary degeneration: Towards a possible in vitro model

Pages 141-144 | Accepted 12 Oct 1994, Published online: 12 Jul 2009

References

  • Smith J S, Kiloh L G. The investigation of dementia: results in 200 consecutive admissions. Lancet 1981; 1: 824–7
  • Schoenberg B S, Kokmen E, Okazaki H. Alzheimer's disease and other dementing illnesses in a defined United States population: incidence rates and clinical features. Ann Neurol 1987; 22: 724–9
  • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239–59
  • Arriagada P V, Growdon J, Hendley-White H. ET, Hyman B T. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 1992; 42: 631–9
  • Kidd M. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 1963; 197: 192–3
  • Lee V MY, Balin B J, Otvos L, Trojanowski J Q. A68 — a major submit of paired helical filaments and derivatized forms of normal tau. Science 1991; 251: 675–8
  • Wischik C M, Novak M, Thogersen H C, Edwards P C, Runswick M J, Jakes R, et al. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer's disease. Proc Natl Acad. Sci USA 1988; 85: 4506–10
  • Goedert M, Jakes R. Expression of separate isoforms of human tau: correlation with the tau pattern in brain and effects on tubulin polymerization. EMBO J 1990; 9: 4225–30
  • Wischik C M, Novak M, Edvards P C, Klug A, Tichelaar W, Crowther R A. Structural characterization of the core of the paired helical filament of Alzheimer's disease. Proc Natl Acad Sci USA 1988; 85: 4884–8
  • Jakes R, Novak M, Davidson M, Wischik C M. Identification of 3-and 4-repeat tau isoforms within the PHF in Alzheimer's disease. EMBO J 1991; 10: 2725–9
  • Crowther R A, Olesen O F, Jakes R, Goedert M. The microtubule binding repeats of tau proteine assemble into filaments like those found in Alzheimer's disease. FEBS Lett 1992; 309: 199–202
  • Crowther R A, Wischik C M. Image reconstruction of the Alzheimer paired helical filament. EMBO J 1985; 4: 3661–5
  • Goedert M, Spillantini M G, Cairns N J, Crowther R A. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 1992; 8: 159–68
  • Sisodia S S, Price D L. Amyloidogenesis in Alzheimer's disease: Basic biology and animal models. Curr Opin Neurobiol 1992; 2: 648–52
  • Bramblett G T, Goedert M, Jakes R, Merrick S F, Trojanowski J Q, Lee V MY. The abnormal phosphorylation of tau at serine 396 in Alzheimer's disease recapitulates phosphorylation during development and contributes to reduced microtubule binding. Neuron 1993; 10: 1089–99

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