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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 44, 2015 - Issue 5
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Original Articles

Evaluation of Immunomodulatory Effects of Mesenchymal Stem Cells Soluble Factors on miR-155 and miR-23b Expression in Mice Dendritic Cells

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Pages 427-437 | Received 02 Dec 2014, Accepted 05 Feb 2015, Published online: 24 Jun 2015

References

  • Ceppi M, Pereira PM, Dunand-Sauthier I, et al. (2009). MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci USA, 24, 2735–40
  • Chen W, Jin W, Hardegen N, et al. (2003). Conversion of peripheral CD4-CD25- naive T cells to CD4-CD-25regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med, 198, 1875–86
  • Choi YS, Jeong JA, Lim DS. (2012). Mesenchymal stem cell-mediated immature dendritic cells induce regulatory T cell-based immunosuppressive effect. Immunol Invest, 41, 214–29
  • Ciesek S, Ringe BP, Strassburg CP, et al. (2005). Effects of cyclosporine on human dendritic cell subsets. Transplant Proc, 37, 20–4
  • Deng Y, Yi S, Wang G, et al. (2014). Umbilical cord-derived mesenchymal stem cells instruct dendritic cells to acquire tolerogenic phenotypes through the IL-6-mediated upregulation of SOCS1. Stem Cells Dev, 23, 2080–92
  • Djouad F, Charbonnier LM, Bouffi C, et al. (2007). Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism. Stem Cells, 25, 2025–32
  • Dunand-Sauthier I, Santiago-Raber ML, Capponi L, et al. (2011). Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function. Blood, 117, 4490–500
  • English K. (2012). Mechanisms of mesenchymal stromal cell immunomodulation. Immunol Cell Biol, 91, 19–26
  • English K, Barry FP, Mahon BP. (2008). Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation. Immunol Lett, 115, 50–8
  • Hu J, Wan Y. (2011). Tolerogenic dendritic cells and their potential applications. Immunology, 132, 307–14
  • Kim YH, Wee YM, Choi MY, et al. (2011). IL-10 induced by CD11b+ cells and IL-10 activated regulatory T cells play a role in immune modulation of mesenchymal stem cells in rat islet allograft. Mol Med, 17, 697–708
  • Kong W, Yang H, He L, et al. (2008). MicroRNA-155 is regulated by TGF {beta}/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol, 28, 6773–84
  • Lindsay MA. (2008). microRNAs and the immune response. Trends Immunol, 29, 343–51
  • Liu W, Zabirnyk O, Wang H, et al. (2010). miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer. Oncogene, 29, 4914–24
  • Liu WN, Liu JJ, Wu J, et al. (2013). Novel mechanism of inhibition of dendritic cells maturation by mesenchymal stem cells via interleukin-10 and the JAK1/STAT3 signaling pathway. Ploseone, 8, e55487
  • Liu XX, Qu X, Chen Y, et al. (2012). Mesenchymal stem/stromal cells induce the generation of novel IL-10–dependent regulatory dendritic cells by Socs3activation. J Immunol, 189, 1182–92
  • Lu C, Huang X, Zhang X, et al. (2011). miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood, 117, 4293–303
  • Lutz MB, Suri RM, Niimi M, et al. (2000). Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo. Eur J Immunol, 30, 1813–12
  • McCoy CE, Sheedy FJ, Qualls JE, et al. (2010). L-10 inhibits miR-155 induction by toll-like receptors. Biol Chem, 285, 20492–8
  • Park S, Kang S, Min KH, et al. (2013). Age-associated changes in microRNA expression in bone marrow derived dendritic cells. Immunol Invest, 42, 179–90
  • Peng Y, Laouar Y, Li MO, et al. (2004). TGF-beta regulates in vivo expansion of Foxp3- expressing CD4-CD25-regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci USA, 101, 4572–7
  • Sadeghi L, Kamali-Sarvestani E, Azarpira N, et al. (2014). Immunomodulatory effects of mice mesenchymal stem cells on maturation and activation of dendritic cells. Iran J Immunol, 11, 177–88
  • Sato K, Yamashita N, Baba M, Matsuyama T. (2003). Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood, 101, 581–9
  • Sauma D, Fierro A, Mora JR, et al. (2003). Cyclosporine preconditions dendritic cells during differentiation and reduces IL-2 and IL-12 production following activation: A potential tolerogenic effect. Transplant Proc, 35, 2515–17
  • Shi M, Liu ZW, Wang FS. (2011). Immunomodulatory properties and therapeutic application of mesenchymal stem cells. Clin Exp Immunol, 164, 1–8
  • Soltani MH, Kalantari T, Karimi MH, et al. (2012). Evaluation of the immunomodulatory effect of curdlan on maturation and function of mouse spleen-derived dendritic cells. Iran J Immunol, 9, 168–74
  • Song SS, Yuan PF, Chen JY, et al. (2014). TGF-β favors bone marrow-derived dendritic cells to acquire tolerogenic properties. Immunol Invest, 43, 360–9
  • Spaggiari GM, Abdelrazik H, Bacchetti F, Moretta L. (2013). MSC inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2. Blood, 113, 6576–83
  • Turner ML, Schnorfeil FM, Brocker T. (2011). MicroRNAs regulate dendritic cell differentiation and function. J Immunol, 187, 3911–17
  • Yagi H, Soto-Gutierrez A, Parekkadan B, et al. (2010). Mesenchymal stem cells: Mechanisms of immunomodulation and homing. Cell Transpl, 19, 667–79
  • Zhang B, Liu R, Shi D, et al. (2009). Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population. Blood, 113, 46–57
  • Zhang W, Ge W, Li C, et al. (2004). Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells. Stem Cells Dev, 13, 263–71
  • Zhao ZG, Xu W, Sun L, et al. (2012). Immunomodulatory function of regulatory dendritic cells induced by mesenchymal stem cells. Immunol Invest, 41, 183–93
  • Zheng J, Jiang HY, Li J, et al. (2012). MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-κB signalling pathways. Allergy, 67, 362–70

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