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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 44, 2015 - Issue 5
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Original Articles

Partial Reversal of Obesity-Induced Insulin Resistance Owing to Anti-Inflammatory Immunomodulatory Potential of Flaxseed Oil

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Pages 451-469 | Received 22 Oct 2014, Accepted 27 Feb 2015, Published online: 24 Jun 2015

References

  • Ahima RS, Flier JS. (2000). Adipose tissue as an endocrine organ. Trends Endocrinol Metab, 11, 327–33
  • Ander BP, Weber AR, Rampersad PP, et al. (2004). Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic rabbits. J Nutr, 134, 3250–6
  • Bachmanov AA, Reed DR, Tordoff MG, et al. (2001). Nutrient preference and diet-induced adiposity in C57BL/6J and 129P3/J mice. Physiol Behav, 72, 603–13
  • Bakari AG, Onyemelukwe GC. (2004). Plasma insulin response to oral glucose tolerance test in type-2 Nigerian diabetics. East Afr Med J, 81, 463–7
  • Boelsma E, Hendriks HFJ, Roza L. (2001). Nutritional skin care: Health effects of micronutrients and fatty acids. Am J Clin Nutr, 73, 853–64
  • Calder PC. (2006). n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr, 83, 1505S–19S
  • Cone RE, Li X, Sharafieh R, et al. (2006). The suppression of delayed-type hypersensitivity by CD8+ regulatory T cells requires interferon-c. Immunology, 120, 112–19
  • Deido W, Dorrell DG. (1977). Factors affecting the pressure extraction of oil from flaxseed. J Am Oil Chem Soc, 54, 313–15
  • Elahi A, Singh MP, Ali S, Khan F. (2014). Antigen specific immune enhancement of innate and acquired immunity by pearl in ashed form. Int Immunopharmacol, 21, 82–93
  • Ghonime M, Emara M, Shawky R, et al. (2015). Immunomodulation of RAW 264.7 murine macrophage functions and antioxidant activities of 11 plant extracts. Immunol Investig (early online), 1–16
  • Gustafson B, Hammarstedt A, Andersson CX, Smith U. (2007). Inflamed adipose tissue. A culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler Thromb Vasc Biol, 27, 2276–83
  • Henninger AJ, Eliasson B, Jenndahl LE, Hammarstedt A. (2014). Adipocyte hypertrophy, inflammation and fibrosis characterize subcutaneous adipose tissue of healthy, non-obese subjects predisposed to type 2 diabetes. PLoS One, 9, e105262
  • Hirosumi J, Tuncman G, Chang L, et al. (2002). A central role for JNK in obesity and insulin resistance. Nature, 420, 333–6
  • Hostmark AT, Lunde MSH, Haug A. (2013). Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. Lipid Health Dis, 12, 92
  • Hulbert AJ, Else PL. (1989). Evolution of mammalian endothermic metabolism: Mitochondrial activity and changes in cellular composition. Am J Physiol, 256, R63–9
  • Ichihara K, Fukubayashi Y. (2010). Preparation of fatty acid methyl esters for gas- liquid chromatography. J Lipid Res, 51, 635–40
  • Kianmehr Z, Soleimanjahi H, Ardestani SK, et al. (2014). Influence of Brucella abortus lipopolysaccharide as an adjuvant on the immunogenicity of HPV-16 L1VLP vaccine in mice. Med Microbiol Immunol, 204, 205--13
  • Lee YS, Li P, Huh JY, et al. (2011). Inflammation is necessary for long-term but not short-term high-fat diet–induced insulin resistance. Diabetes, 60, 2474–83
  • Liu F, Kim JK, Li Y, et al. (2001). An extract of Lagerstroemia speciosa L. has insulin-like glucose uptake – Stimulatory and adipocyte differentiation – Inhibitory activities in 3T3-L1 cells. J Nutr, 131, 2242–7
  • Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR. (2008). Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes, 57, 3239–46
  • McDaniel JC, Belury M, Ahijevych K, Blakely W. (2008). ω-3 fatty acids effect on wound healing. Wound Repair Regen, 16, 337–45
  • McNelis JC, Olefsky JM. (2014). Macrophages, immunity and metabolic disease. Immunity, 41, 36–48
  • Parekh PI, Petro AE, Tiller JM, et al. (1998). Reversal of diet-induced obesity and diabetes in C57BL/6J mice. Metabolism, 47, 1089--96
  • Philip DGM, Barak Y, He W, et al. (2000). Improved insulin-sensitivity in mice heterozygous for PPAR-g deficiency. J Clin Invest, 105, 287–92
  • Razmkhah M, Jaberipour M, Ghaderi A. (2011). Bcl-2 and Fas expressions correlate with proliferative specificity of adipose-derived stem cells (ASCs) in breast cancer. Immunol Investig, 40, 290–8
  • Rolls BJ, Rowe EA, Turner RC. (1980). Persistent obesity in rats following a period of consumption of a mixed, high energy diet. J Physiol, 298, 415–27
  • Rubab I, Routray I, Mahmood A, et al. (2013). Mineral pitch stimulates humoral, cellular and innate immune responses in mice. Pharmaceut Biol, 51, 997–1007
  • Swanson D, Block R, Mousa SA. (2012). Omega-3 fatty acids EPA and DHA: Health benefits throughout life. Adv Nutr, 3, 1–7
  • Thorburn AW, Storlein LH, Jenkins AB, et al. (1989). Association between fructose- induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am J Clin Nutr, 49, 1155–63
  • Yamasaki M, Kitagawa T, Koyanagi N, et al. (2000). Dietary effect of pomegranate seed oil on immune function and lipid metabolism in mice. Nutrition, 22, 54–9
  • Ye J. (2013). Mechanisms of insulin resistance in obesity. Front Med, 7, 14–24
  • Ye J, McGuinness OP. (2013). Inflammation during obesity is not all bad: Evidence from animal and human studies. Am J Physiol Endocrinol Metab, 304, E466–77
  • Zanini S, Marzotto M, Giovinazzo F, et al. (2014). Effects of dietary components on cancer of the digestive system. Crit Rev Food Sci Nutr (early online)
  • Zheng W, Flavell RA. (1997). The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell, 16, 587–96

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