Regulation of Lineage Commitment during Lymphocyte Development

References

• Weissman I. L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000; 100(1)157
   PubMed Web of Science ®Google Scholar
• Arnold H. H., Braun T. Genetics of muscle determination and development. Curr. Top. Dev. Biol. 2000; 48: 129
   PubMedGoogle Scholar
• Black B. L., Olson E. N. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu. Rev. Cell Dev. Biol. 1988; 14: 167
   Google Scholar
• Firulli A. B., Olson E. N. Modular regulation of muscle gene transcription: a mechanism for muscle cell diversity. Trends Genet. 1997; 13(9)364
   Google Scholar
• Boryeki A. G., Emerson C. P. Multiple tissue interactions and signal transduction pathways control somite myogenesis. Curr. Top. Dev. Biol. 2000; 48: 165
   Google Scholar
• Dzierzak E., Medvinsky A., de Bruijn M. Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo. Immunol. Today 1998; 19(5)228
   Google Scholar
• Choi K. Hemangioblast development and regulation. Biochem. Cell Biol. 1998; 76(6)947
   Google Scholar
• Morrison S., Uchida N., Weissman I. The biology of hematopoietic stem cells. Ann. Rev. Dev. Biol. 1995; 11: 35
   PubMed Web of Science ®Google Scholar
• Kawamoto H., Ohmura K., Katsura Y. Presence of progenitors restricted to T, B, or myeloid lineage, but absence of multipotent stem cells, in the murine fetal thymus. J. Immunol. 1998; 161(8)3799
   Google Scholar
• Ikawa T., Kawamoto H., Fujimoto S., Katsura Y. Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J. Exp. Med. 1999; 190(11)1617
   Google Scholar
• Metealf D. Lineage commitment and maturation in hematopoietic cells: the case for extrinsic regulation. Blood 1998; 92(2)345
   Google Scholar
• Allen R.D., III, Bender T. P., Siu G. c-Myb is essential for early T cell development. Genes Dev. 1999; 13(9)1073
   Google Scholar
• McKercher S. R., Torbelt B. E., Anderson K. L., Henkel G. W., Vestal D. J., Baribault H., Klemsz M., Feeney A. J., Wu G. E., Paige C. J., Maki R. A. Targeted disruption of the PU.I gene results in multiple hematopoietic abnormalities. Embo J. 1996; 15(20)5647
   PubMed Web of Science ®Google Scholar
• Scott E. W., Simon M. C., Anastasi J., Singh H. Requirement of transcription factor PU.I in the development of multiple hematopoietic lineages. Science 1994; 265(5178)1573
   PubMed Web of Science ®Google Scholar
• Georgopoulos K., Moore D. D., Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science 1992; 258(5083)808
   PubMed Web of Science ®Google Scholar
• Wang J. H., Nichogiannopoulou A., Wu L., Sun L., Sharpe A. H., Bigby M., Georgopoulos K. Selective deflects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996; 5(6)537
   PubMed Web of Science ®Google Scholar
• Georgopoulos K., Bigby M., Wang J. H., Molnar A., Wu P., Winandy S., Sharpe A. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994; 79(1)143
   PubMed Web of Science ®Google Scholar
• Morgan B., Sun L., Avitahl N., Andrikopoulos K., Ikeda T., Gonzales E., Wu P., Neben S., Georgopoulos K. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. Embo J. 1997; 16(8)2004
   PubMed Web of Science ®Google Scholar
• Kelley C. M., Ikeda T., Koipally J., Avitahl N., Wu L., Georgopoulos K., Morgan B. A. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 1998; 8(9)508
   PubMed Web of Science ®Google Scholar
• Hahm K., Cobb B. S., McCarty A. S., Brown K. E., Klug C. A., Lee R., Akashi K., Weissman I. L., Fisher A. G., Smale S. T. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev. 1998; 12(6)782
   PubMed Web of Science ®Google Scholar
• Kondo M., Weissman I. L., Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997; 91(5)661
   PubMed Web of Science ®Google Scholar
• Kondo M., Akashi K., Domen J., Sugamura K., Weissman I. L. Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice. Immunity 1997; 7(1)155
   PubMed Web of Science ®Google Scholar
• Akashi K., Kondo M., Weissman I. L. Role of interleukin-7 in T-cell development from hematopoietic stem cells. Immunol. Rev. 1998; 165: 13
   PubMed Web of Science ®Google Scholar
• von Freeden-Jeffry U, Vieira P., Lucian L. A., McNeil T., Burdach S. E., Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 1995; 181(4)1519
   PubMed Web of Science ®Google Scholar
• Peschon J. J., Morrissey P. J., Grabstein K. H., Ramsdell F. J., Maraskovsky E., Gliniak B. C., Park L. S., Ziegler S. F., Williams D. E., Ware C. B. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 1994; 180((5))
   Google Scholar
• Okada S., Nakauchi H., Nagayoshi K., Nishikawa S., Miura Y., Suda T. In vivo and in vitro stem cell function of c-kit-and Sca-I-positive murine hematopoietic cells. Blood 1992; 80(12)3044
   Google Scholar
• Katayama N., Shih J. P., Nishikawa S., Kina T., Clark S. C., Ogawa M. Stage-specific expression of c-kit protein by murine hematopoietic progenitors. Blood 1993; 82(8)2353
   Google Scholar
• Lyman S. D., Brasel K., Rousseau A. M., Williams D. E. The flt3 ligand: a hematopoietic stem cell factor whose activities are distinct from steel factor. Stem Cells 1994; 12, (Suppl 1)
   Google Scholar
• Mackarehtschian K., Hardin J. D., Moore K. A., Boast S., Goff S. P., Lemischka I. R. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 1995; 3(1)147
   PubMed Web of Science ®Google Scholar
• Matsuzaki Y., Nakayama K., Toinita T., Isoda M., Loh D. Y., Nakauchi H. Role of bc1–2 in the development of lymphoid cells from the hematopoietic stem cell. Blood 1997; 89(3)853
   Google Scholar
• Rodewald H. R., Ogawa M., Haller C., Waskow C., DiSanto J. P. Pro-thymocyte expansion by c-kit and the common cytokine receptor gamma chain is essential for repertoire formation. Immunity 1997; 6(3)265
   Google Scholar
• Zhuang Y., Soriano P., Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell 1994; 79(5)875
   Google Scholar
• Bain G., Maandag E. C., Izon D. J., Amsen D., Kruisbeek A. M., Weintraub B. C., Krop I., Schlissel M. S., Feeney A. J., van Roon M. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 1994; 79(5)885
   Google Scholar
• Bain G., Maandag E.C. Robanus, Riele H.P. te, Feeney A. J., Sheehy A., Schlissel M., Shinton S. A., Hardy R. R., Murre C. Both E12 and E47 allow commitment to the B cell lineage. Immunity 1997; 6(2)145
   Google Scholar
• Lin H., Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 1995; 376(6537)263
   Google Scholar
• Urbanck P., Wang Z. Q., Fetka I., Wagner E. F., Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 1994; 79(5)901
   Google Scholar
• Thevenin C., Nutt S. L., Busslinger M. Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis. J. Exp. Med. 1998; 188(4)735
   Google Scholar
• Nutt S. L., Heavey B., Relink A. G., Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999; 401(6753)556
   Web of Science ®Google Scholar
• Rolink A. G., Nutt S. L., Melchers F., Busslinger M. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors. Nature 1999; 401(6753)603
   PubMed Web of Science ®Google Scholar
• Enver T. B-cell commitment: Pax5 is the deciding factor. Curr. Biol. 1999; 9(24)R933
   Google Scholar
• Chiang M. Y., Monroe J. G. BSAP/Pax5A expression blocks survival and expansion of early myeloid cells implicating its involvement in maintaining commitment to the B-lymphocyte lineage. Blood 1999; 94(11)3621
   Google Scholar
• Schilham M. W., Oosterwegel M. A., Moerer P., Ya J., Boer P.A. de, Wetering M. van de, Verbeek S., Lamers W. H., Kruisbeek A. M., Cumano A., Clevers H. Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature 1996; 380(6576)711
   PubMed Web of Science ®Google Scholar
• Schilham M. W., Moerer P., Cumano A., Clevers H. C. Sox-4 facilitates thymocyte differentiation. Eur. J. Immunol. 1997; 27(5)1292
   Google Scholar
• Pui J. C., Aliman D., Xu L., DeRocco S., Karnell F. G., Bakkour S., Lee J. Y., Kadesch T., Hardy R. R., Aster J. C., Pear W. S. Notchl expression in early lymphopoiesis influences B versus T lineage determination. Immunity 1999; 11(3)299
   Google Scholar
• Quong M. W., Harris D. P., Swain S. L., Murre C. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. Embo. J. 1999; 18(22)6307
   Google Scholar
• Marine J., Winoto A. The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements. Proc. Natl. Acad. Sci. USA 1991; 88(16)7284
   Google Scholar
• Ko L. J., Yamamoto M., Leonard M. W., George K. M., Ting P., Engel J. D. Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. Mol. Cell Biol. 1991; 11(5)2778
   PubMedGoogle Scholar
• Ho I. C., Vorhees P., Marin N., Oakley B. K., Tsai S. F., Orkin S. H., Leiden J. M. Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. Embo J. 1991; 10(5)1187
   PubMed Web of Science ®Google Scholar
• Pandolfi P. P., Roth M. E., Karis A., Leonard M. W., Dzierzak E., Grosveld F. G., Engel J. D., Lindenbaum M. H. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver hematopoiesis. Nat. Genet. 1995; 11(1)40
   Google Scholar
• Ting C. N., Olson M. C., Barton K. P., Leiden J. M. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 1996; 384(6608)474
   PubMed Web of Science ®Google Scholar
• Hendriks R. W., Nawijn M. C., Engel J. D., van Doorninck H, Grosveld F., Karis A. Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. Eur. J. Immunol. 1999; 29(6)1912
   Google Scholar
• Waterman M. L., Jones K. A. Purification of TCF-l alpha, a T-cell-specific transcription factor that activates the T-cell receptor C alpha gene enhancer in a context-dependent manner. New Biol. 1990; 2(7)621
   Google Scholar
• Castrop J., Wichen D. van, Koomans-Bitler M., Wetering M. van de, Wezer R. de, Dongen J. van, Clevers H. The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes. Blood 1995; 86(8)3050
   Google Scholar
• Wetering M. van de, Oosterwegel M., Dooijes D., Clevers H. Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box. Embo J. 1991; 10(1)123
   Google Scholar
• Oosterwegel M., van deWetering M, Timmerman J., Kruisbeek A., Destree O., Meijlink F., Clevers H. Differential expression of the HMG box factors TCF-1 and LEF-I during murine embryogcnesis. Development 1993; 118(2)439
   Google Scholar
• Oosterwegel M., van deWetering M, Dooijes D., Klomp L., Winoto A., Georgopoulos K., Meijlink F., Clevers H. Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers. J. Exp. Med. 1991; 173(5)1133
   Google Scholar
• Verbeek S., Izon D., Hofhuis F., Robanus-Maandag F., Ricle H. te, Wetering M. van de, Oosterwegel M., Wilson A., MacDonald H. R., Clevers H. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 1995; 374(6517)70
   PubMedGoogle Scholar
• Schilham M. W., Wilson A., Moerer P., Benaissa-Trouw B. J., Cumano A., Clevers H. C. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 1998; 161: 3984
   PubMed Web of Science ®Google Scholar
• Okamura R., Sigvardsson M., Galceron J., Verbeek S., Clevers H., Grosscedl R. Overlapping functions of Tcf-1 and Lef-1 in T lymphocyte development. Immunity 1998; 8: 11
   PubMed Web of Science ®Google Scholar
• Okamura R. M., Sigvardsson M., Galceran J., Verbeek S., Clevers H., Grosschedl R. Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 1998; 8(1)11
   Google Scholar
• Molenaar M., van D.W.M, Oosterwegel M., Peterson M. J., Godsave S., Korinek V., Roose J., Destree O., Clevers H. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996; 86(3)391
   Google Scholar
• Staal F. J., Burgering B. M., van deWetering M, Clevers H. C. Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells. Int. Immunol. 1999; 11(3)317
   Google Scholar
• Cadigan K. M., Nusse R. Wnt signaling: a common theme in animal development. Genes & Dev. 1998; 12: 1
   Google Scholar
• Young C. S., Kitamura M., Hardy S., Kitajewski J. Wnt-l induces growth, cylosolic β-catenin, and Tcf/Lef transcriptional activation in Rat-l fibroblasts. Mol. Cell Biol. 1998; 18(5)2474
   PubMedGoogle Scholar
• Korinek V., Barker N., Willert K., Molenaar M., Roose J., Wagenaar G., Markman M., Lamers W., Desiree O., Clevers H. Two members of the Tcf family implicated in Wnt/β-catenin signaling during embryogenesis in the mouse. Mol. Cell Biol. 1998; 18(3)1248
   PubMedGoogle Scholar
• Clevers H., van deWetering M. TCF/LEF factor earn their wings. Trends Genet. 1997; 13(12)485
   Google Scholar
• Hattori N., Kawamoto H., Fujimoto S., Kuno K., Katsura Y. Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus. J. Exp. Med. 1996; 184(3)1137
   Google Scholar
• Muthusamy N., Barton K., Leiden J. M. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature 1995; 377(6550)639
   Google Scholar
• Langlands K., Yin X., Anand G., Prochownik E. V. Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. J. Biol. Chem. 1997; 272(32)19785
   Google Scholar
• Rivera R. R., Johns C. P., Quan J., Johnson R. S., Murre C. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity 2000; 12(1)17
   Google Scholar
• Morrow M. A., Mayer E. W., Perez C. A., Adlam M., Siu G. Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. Mol. Immunol. 1999; 36(8)491
   Google Scholar
• Janatpour M. J., McMaster M. T., Genbaeev O., Zhou Y., Dong J., Cross J. C., Israel M. A., Fisher S. J. Id-2 regulates critical aspects of human cytotrophoblast differentiation, invasion and migration. Development 2000; 127(3)549
   Google Scholar
• Yokota Y., Mansouri A., Mori S., Sugawara S., Adachi S., Nishikawa S., Gruss P. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 1999; 397(6721)702
   Google Scholar
• Heemskerk M. H., Blom B., Nolan G., Stegmann A. P., Bakker A. Q., Weijer K., Res P. C., Spits H. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J. Exp. Med. 1997; 186(9)1597
   Google Scholar
• Artavanis-Tsakonas S., Rand M. D., Lake R. J. Notch signaling: cell fate control and signal integration in development. Science 1999; 284(5415)770
   PubMed Web of Science ®Google Scholar
• Kim H. K., Siu G. The notch pathway intermediate HES-1 silences CD4 gene expression. Mol. Cell Biol. 1998; 18(12)
   Google Scholar
• Robey E., Chang D., Itano A., Cado D., Alexander H., Lans D., Weinmaster G., Salmon P. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 1996; 87(3)483
   Web of Science ®Google Scholar
• Radtke F., Wilson A., Stark G., Bauer M., van Meerwijk J, MacDonald H. R., Aguet M. Deficient T cell fate specification in mice with an induced inactivation of Notchl. Immunity 1999; 10(5)547
   PubMed Web of Science ®Google Scholar
• Kaneta M., Osawa M., Sudo K., Nakauchi H., Farr A. G., Takahama Y. A role for pref-l and HES-l in thymocyte development. J. Immunol. 2000; 164(1)256
   Google Scholar
• Tomita K., Hattori M., Nakamura E., Nakanishi S., Minato N., Kageyama R. The bHLH gene Hesl is essential for expansion of early T cell precursors. Genes Dev. 1999; 13(9)1203
   Google Scholar
• John B. M., Bielke W., Pear W. S., Osborne B. A. Protective effects of notch-l on TCR-induced apoptosis. J. Immunol. 1999; 162(2)635
   Google Scholar
• Hasserjian R. P., Aster J. C., Davi F., Weinberg D. S., Sklar J. Modulated expression of notchl during thymocyte development. Blood 1996; 88(3)970
   Google Scholar
• Felli M. P., Maroder M., Mitsiadis T. A., Campese A. F., Bellavia D., Vacca A., Mann R. S., Frati L., Lendahl U., Gulino A., Screpanti I. Expression pattern of notchl, 2 and 3 and Jagged 1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intralhymic T cell development. Int. Immunol. 1999; 11(7)1017
   Google Scholar
• Deftos M. L., He Y. W., Ojala E. W., Bevan M. J. Correlating notch signaling with thymocyte maturation. Immunity 1998; 9(6)777
   Google Scholar