Pathogenic Subsets of Antibodies to DNA

References

• Smith H. R., Green D. R., Raveche E. S., Smathers P. A., Gershon R. K., Steinberg A. D. Studies of the induction of anti-DNA antibodies in normal mice. J. Immunol. 1982; 129: 2332–2336
   PubMed Web of Science ®Google Scholar
• Rubin R. L., Carr R. I. Anti-DNA activity of IgG(ab'), from normal human seru. J. Immunol. 1979; 122: 1604–1607
   PubMed Web of Science ®Google Scholar
• Hock S., Schur P. H., Schwaher J. Frequency of anti-DNA antibody producing cells from normals and patients with SLE. Clin. Immunol. Immunopathol. 1983; 27: 28–32
   PubMedGoogle Scholar
• Fish F., Zift M. The in vitro and in vivo induction of anti-ds-DNA antibodies in normal and autoimmune mice. J. Immunol. 1982; 128: 419–414
   Web of Science ®Google Scholar
• Shoenleld Y., Andre-Schwartz J., Stollar H. D., Schwartz R. S. Anti-DNA antibodies. Systemic Lupus Erythematosus, R. G. Lahita. John Wiley & Sons, Inc., Boston 1987; 213–255
   Google Scholar
• Tan E. M., Stoughton R. B. UV light alteration of cellular DNA in vivo. Proc. Natl. Acad. Sri. USA 1969; 62: 708–711
   PubMed Web of Science ®Google Scholar
• Schoenfeld Y., Rauch J., Massicotte H., Datta S. K., Andre-Schwartz J., Stollar B. D., Schwartz R. S. Polyspecificity of monoclonal lupus antibodies produced by human-human hybridomas. N. Eng. J. Med. 1983; 308: 414–418
   PubMed Web of Science ®Google Scholar
• Dighiero G., Guilbert B., Fermand J. P., Dunon P. F., Avrameas S. Thirty-six human monoclonal immunoglobulins with antibody activity against cytoskeleton proteins, thyroglobulin and native DNA: immunologic studies and clinical correlations. Blood 1983; 62: 264–270
   PubMed Web of Science ®Google Scholar
• Jacob L., Tron F., Bach J-F., Louvard D. A monoclonal anti-DNA antibody also binds to cell-surface proteins. Proc. Natl. Acad. Sci. USA 1984; 81: 3843–3845
   PubMed Web of Science ®Google Scholar
• Rauch J., Tannenbaum H., Stollar B. D., Schwartz R. S. Monoclonal anti-cardiolipin antibodies bind to DNA. Eur: J Immunol. 1984; 14: 529–534
   PubMed Web of Science ®Google Scholar
• Schwartz R. S., Stollar B. D. Origins of anti-DNA antibodies. J. Clin Invest. 1985; 75: 321–327
   PubMed Web of Science ®Google Scholar
• Gilkeson G. S., Grudier J. P., Pisetsky D. S. Response of normal mice to dsDNA immunization. Arthritis Rhcum. 1988; 31: S39, abstract)
   Google Scholar
• Diamond B. M. Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc. Natl. Acad Sci. (USA) 1984; 81: 5841–5844
   PubMed Web of Science ®Google Scholar
• Feikje J., Van Rappard-van der Veen R. M., Golink A. G., Gleichman E. Disease caused by reaction to T lymphocytes toward incompatible structures of the major histocompatibility complex. J. Exp. Med. 1982; 155: 1555–1560
   PubMedGoogle Scholar
• Portanova J. P.H. N., Kotzin B. C. Auto-immunization in murine graft-versus-host disease. I. Selective production ol antibodies to histone and DNA. J. Immunol. 1985; 135: 3850–3854
   PubMed Web of Science ®Google Scholar
• Ebling F. M., Ando D. G., Panosian-Sahakian N., Kaluian K. C., Hahn B. H. Idiotypic spreading promotes the production of pathogenic autoantibodies. J. Autoimmunity 1988; 1: 47–61
   PubMed Web of Science ®Google Scholar
• Koffler D., Schui P. H., Kunkel H. G. Imimmolouical studies concerning the nephritis of systemic lupus erythematosu. J. Exp. Med. 1967; 126: 607–624
   PubMed Web of Science ®Google Scholar
• Tan F. M. Immunopathologs and pathogenesis of cutancous involvement in systemic lupus erythematosus. J. Invest. Dermatl. 1976; 67: 360–365
   PubMed Web of Science ®Google Scholar
• Theofilopoulos A. N., Dixon F. J. Murine models of SL. Adv: Immnuol. 1985; 37: 269–390
   PubMed Web of Science ®Google Scholar
• Schui P. H., Sandson J. Immunologic tactots and clinical activity in lupus erythematosus. N. Engl. J. Med. 1968; 278: 533–538
   PubMed Web of Science ®Google Scholar
• Weinstein A., Bordwell B., Stone B., Tibbcls C., Rothtield N. R. Antibodies to native DNA and serum complement (C3) levels. Am J. Med. 1983; 74: 206–216
   PubMed Web of Science ®Google Scholar
• Lambert P H, Dixon F. J. Pathogenesis of glomerulonephritis of NZB/W mice. J. Exp. Med. 1968; 127: 507–522
   PubMed Web of Science ®Google Scholar
• Parker L. P., Hahn B. H., Osterland C. K. Modification of NZB/N7W F1 autoimmune disease by development of tolerance to DNA. J. Immunol. 1974; 113: 292–312
   PubMed Web of Science ®Google Scholar
• Borel Y., Lewis R. M., Andre-Schwartz J., Slollar B. D., Deinen L. Treatment of lupus nephritis in adult (NZB NZW) F1 mice by cortisone-facilitated tolerance to nucleic acid antigens. J. Clin. Invest. 1978; 61: 276–286
   PubMed Web of Science ®Google Scholar
• Borel H., Bastian D., Cooper B., Borel Y. A possible new therapy of systemic lupus erythematosus (SLE). Ann. N.Y. Acad. Sci. 1986; 475: 206–216
   Web of Science ®Google Scholar
• Maddison P., Reichlin M. Deposition of antibodies to a soluble cytoplasmic antigen in the kidneys of patients with systemic lupus erythematosus. Arthritis Rheum. 1979; 22: 858–863
   PubMed Web of Science ®Google Scholar
• Andrews B. S., Fisenberg R. A., Theofilopoulos A. N., Izui S. N., Wilson C. B., McConane P. S., Murphy H. D., Roths J. B., Dixon J. B. Spontaneous murine lupus-like syndromes. J. Exp. Med. 1978; 148: 1198–1215
   PubMed Web of Science ®Google Scholar
• Ebling F. M., Hahn B. H. Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus. Comparison of antibodies in serum and renal eluates. Arthritis Rheum. 1980; 23: 392–403
   PubMed Web of Science ®Google Scholar
• Galvachin J., Nicklas J. A., Eastcott J. W., Madaio M. P., Stollar B. D., Schwartz R. S., Datta S. K. Lupus-prone (SWR NZB) F1 mice produce potentially nephritogenic antibodies inherited from the normal SWR parent. J. Immunol. 1985; 134: 885–890
   PubMed Web of Science ®Google Scholar
• Rothtield N. F., Stollar B. D. The relation of immunoglobulin class, pattern of anti-nuclear antibody, and complement-fixing antibodies to DNA in sera from patients with systemic lupus erythematosus. J. Clin. Invest. 1967; 46: 1785–1794
   PubMed Web of Science ®Google Scholar
• Sontheimer R. D., Gilliam J. N. DNA antibody class, subclass, and complement fixation in systemic lupus erythematosus with and without nephritis. Clin. Immunol. Immunopathol. 1978; 10: 459–467
   PubMedGoogle Scholar
• Winfield J. B., Faiferman I., Koffler D. Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis. J. Clin. Invest. 1977; 59: 90–96
   PubMed Web of Science ®Google Scholar
• Gershwin E. M., Steinberg A. D. Qualitative characteristics of anti-DNA antibodies in lupus nephritis. Arthritis Rheum. 1974; 17: 947–954
   PubMedGoogle Scholar
• Johnson G. D., Edmonds J. P., Holborow D. J. Precipitating antibody to DNA detected by two-stage electroinimunodiffusion: studies in SLE and in rheumatoid arthritis. Lancet 1973; 2: 883–885
   PubMed Web of Science ®Google Scholar
• Border W. A., Ward H. J., Kamil E. S., Cohen A. H. Induction of membranous nephropathy in rabbits by administration of catiomc antigen. J. Clin. Invest. 1982; 69: 451–456
   PubMed Web of Science ®Google Scholar
• Dang H., Harbeck R. J. The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice. Clin. Immunol Immunopathol. 1984; 30: 265–270
   PubMedGoogle Scholar
• Galvachin J., Seder R. A., Datta S. K. The NZB SWR model of lupus nephritis, I. Cross-reactive idiotypes of monoclonal anti-DNA antibodies in relation to antigenic specificity, charge and allotype. Identification of inter-connected idiotype families inherited from the normal SWR and the autoimmune NZB parents. J. Immunol. 1986; 138: 128–137
   Web of Science ®Google Scholar
• Yoshida H. M., Yoshida S., Izui S., Lambert P. H. Distinct clonotypes of anti-DNA antibodies in mice with lupus nephritis. J. Clin. Invest. 1985; 76: 586–694
   PubMed Web of Science ®Google Scholar
• Izui J., Lambert P. H., Miescher P. A. In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. J. Exp. Med. 1976; 144: 428–443
   PubMed Web of Science ®Google Scholar
• Jacob L., Lety M-A., Monteiro R. C., Jacob F., Bach J-F., Louvard D. Altered cell-surface proteim(s), crossreactive with DNA. on spleen cells of autoimmune lupie mice. Proc. NaTl. AcAD. SCi. (USA) 1987; 84: 1361–1363
   PubMed Web of Science ®Google Scholar
• Mannik M., Gauthier V. J., Stapleton S. A., Agodoa L. Y. C. Immune complexes with catiomc antibodies deposit in glomeruli more effectively than cationic antibodies alone. J. Immunol. 1987; 38: 4209–4217
   Google Scholar
• Stollar B. D., Zon G., Pastor R. W. A recognition site in synthetic helical oligonucleotides for monoclonal anti-native DNA autoantibody. Proc. Natl. Acad. Sci. (USA) 1986; 83: 4469–4476
   PubMed Web of Science ®Google Scholar
• Gilliam A. C., Lang D., LoSpalluto J. J. Antibodies to dsDNA: Purification and characterization of binding specificities. J. Immunol. 1980; 125: 874–885
   PubMed Web of Science ®Google Scholar
• Munns T. W., Liszewski M. K., Hahn B. H. Antibody-nucleic acid complexes. Conformational and base specificities associated with spontaneously occurring poly- and monoclonal anti-DNA antibodies from autoimmune mice. Biocrhemistry 1984; 23: 2964–2970
   PubMed Web of Science ®Google Scholar
• Shoenleld Y., Zamir R., Joshua H., Lavie G., Pinkhas J. Human monoclonal anti-DNA antibodies react as lymphocytotoxic antibodies. Eur. J. Immunol. 1985; 15: 1024–1028
   PubMed Web of Science ®Google Scholar
• Bankhurst A. D., Williams R. C. Identification of DNA-Binding lymphocytes in patients with systemic lupus erythematosus. J. Clin. Invest. 1975; 56: 1378–1385
   PubMed Web of Science ®Google Scholar
• Bennett R. M., Gabor G. T., Merritt M. M. DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization. and degradation of DNA. J. Clin. Invest. 1985; 76: 2182–2190
   PubMed Web of Science ®Google Scholar
• Rauch J., Murphy E., Roths J. B., Slollar B. D., Schwartz R. S. A high frequency idiotypic marker of anti-DNA antibodies in MRL-lpr/lpr mice. J. Immunol. 1982; 129: 236–242
   PubMed Web of Science ®Google Scholar
• Marion T. N., Lawton A. R., Kearney J. E, Briles D. E. Anti-DNA antibodies in (NZB/NZW) Fl mice are clonally heterogenous but the majority share a common idiotype. J. Immunol. 1982; 128: 668–671
   PubMed Web of Science ®Google Scholar
• Tron R., Guerm C., Cazenave P. A., Bach J-F. Intrastrain recurrent idiotypes among anti-DNA antibodies of (NZB NZW) F1 hybrid mice. Eur. J. Immunol. 1982; 12: 761–766
   PubMed Web of Science ®Google Scholar
• Hahn B. H., Bbling F. M. A public idiotype is present on spontaneous cationic IgG antibodies to DNA from mice of unrelated lupus-prone strains. J. Immunol. 1984; 133: 3015–3019
   PubMed Web of Science ®Google Scholar
• Hahn B. H., Ebling F. M. Idiotype restriction in murine lupus: High frequency of three public idiotypes on serum IgG in nephritic NZB/NZW F1 mice. J. Immunol. 1987; 138: 2110–2118
   PubMed Web of Science ®Google Scholar
• Eilat D., Rischel R., Zlotnick A. A central anti-DNA idiotype in human and murine systemic lupus erythematosus. Eur. J. Immunol. 1985; 15: 368–375
   PubMed Web of Science ®Google Scholar
• Galvachin J., Datta S. K. The NZB/SWR model of lupus nephritis. II. Autoantibodies deposited in renal lesions show a distinctive and restricted idiotypic diversity. J. Immunol. 1987; 138: 138–148
   PubMed Web of Science ®Google Scholar
• Shoenfeld Y., Isenberg D. A., Rauch J., Madaio M. P., Stollar B. D., Schwartz R. S. Idiotypic cross-reactions of monoclonal human lupus autoantibodies. J. Exp. Med. 1983; 158: 718–730
   PubMed Web of Science ®Google Scholar
• Isenberg D. A., Shoenfeld Y., Madaio M. R., Rauch J., Reichlin M., Stollar B. D., Schwartz R. S. Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet 1984; 2: 417–4221
   PubMed Web of Science ®Google Scholar
• Solomon G., Schiffenbauer J., Reiser H. D., Diamond B. Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus. Proc. Natl. Acad. Sci. (USA) 1983; 80: 850–853
   PubMed Web of Science ®Google Scholar
• Shoenfeld Y., Isenberg D. A. DNA antibody idiotypes: A review of their genetic, clinical and immuno-pathologic features. Sem. Arthritis Rheum. 1987; 16: 215–252
   Web of Science ®Google Scholar
• Kalunian K., Panosian N., Kaine J., Louie J., Cohen A., Ebling F. M., Hahn B. H. A single idiotype (Id) dominates nephritogenic antibodies in human SLE. Arthritis Rheum. 1989; 32: 513–521
   PubMedGoogle Scholar
• Hahn B. H., Ando D. G., Dunn K., Ebling F. M., Sercarz E. E. Idiotype regulatory networks promote autoantibody formation. J. Rheumatol. 1987; 14: 143–148
   Web of Science ®Google Scholar
• Teitelbaum D., Rauch J., Stollar B. D., Schwartz R. S. In vivo effects of antibodies against a high frequency idiotype of anti-DNA antibodies in MRL mice. J. Immunol. 1984; 132: 1282–1285
   PubMed Web of Science ®Google Scholar
• Hahn B. H., Ebling F. M. Suppression of murine lupus nephritis by administration of an anti-idiotypic antibody to anti-DNA. J. Immunol. 1984; 132: 187–190
   PubMed Web of Science ®Google Scholar
• Mendlovic S., Brocke S., Shoenfeld Y., Ben-Bassal M., Meshorer A., Bakimer R., Mozes E. Induction of a systemic lupus erythematosus-like disease in mice by a common human anti-DNA idiotype. Proc. Natl. Acad. Sci (USA) 1988; 85: 2260–2264
   PubMed Web of Science ®Google Scholar
• Pancer L. B., Milazzo M. E, Morris V. L., Singhal S. K., Bell D. Immunogenicity and characterization of supernatant DNA released by murine spleen cells. J. Immunol. 1981; 127: 98–104
   PubMed Web of Science ®Google Scholar
• Golan D. T., Borel Y. Spontaneous increase of DNA turnover in murine systemic lupus erythematosus. Eur. J. Immunol. 1983; 13: 430–433
   PubMed Web of Science ®Google Scholar
• Sano H., Imokawa M. Steinberg, A. D., Morimoto, C. Accumulation of guanine-cytosine-enriched low M.W. DNA fragments in lymphocytes of patients with systemic lupus erythematosus. J. Immunol. 1983; 130: 187–190
   PubMed Web of Science ®Google Scholar
• Emlen W., Mannik M. Effect of DNA size and strandedness on the in vivo clearance and organ localization of DNA. Clin. Exp. Immunol. 1984; 56: 185–192
   PubMed Web of Science ®Google Scholar
• Emlen W., Ansari R., Burdick G. DNA-anti DNA immune complexes: antibody protection of a discrete DNA fragment from DNAse digestion in vitr. J. Clin. Invest. 1984; 74: 185–190
   PubMed Web of Science ®Google Scholar
• Frost P. G., Lachmann P. J. The relationship of desoxyribonuclcase inhibitor levels in human sera to the occurrence of antinuclear antibodies. Clin. Exp. Immunol. 1968; 3: 447–451
   PubMedGoogle Scholar
• Chitrabamrung S., Rubin F. L., Tan F. M. Low serum deoxyribonuclease I activity in systemic lupus erythematosus. Arthritis Rheum. 1981; 24: S123, abstract
   Google Scholar
• Taylor R. P., Morgan C. Quantitative determination of anti-dsDNA antibodies and antibody/dsDNA stoichi-ometries in prepared, soluble complement-fixing antibody/dsDNA complexes. Mol. Immunol. 1984; 21: 853–862
   PubMed Web of Science ®Google Scholar
• Burdick G., Emlen W. Effect of antibody excess on the size, stoichiometry and DNAse resistance of DNA anti-DNA immune complexes. J. Immunol. 1985; 135: 2593–2597
   PubMed Web of Science ®Google Scholar
• Frank M. M., Hamburger M. I., Lawley T. J., Kimberly R. P., Plotz P. H. Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. N. Engl. J. Med. 1979; 300: 518–523
   PubMed Web of Science ®Google Scholar
• Mayakawa Y., Yamada A., Kosaka K., Tsuda F., Kosugi E., Mayumi M. Defective immune-adherence (C3b) receptor on eruthrocytes from patients with systemic lupus erythematosus. Lancet 1981; 2: 493–497
   PubMed Web of Science ®Google Scholar
• Wilson J. G., Wong W. W., Schur P. H., Fearon D. T. Mode of inheritance of decreased C3b receptors on erythrocytes of patients with systemic lupus erythemalosus. N. Engl. J. Med. 1982; 307: 981–986
   PubMed Web of Science ®Google Scholar
• Pearson L., Lightfoot R. W. Correlation of DNA-anti-DNA association rates with clinical activity in systemic lupus erythematosus. J. Immunol. 1981; 126: 16–19
   PubMed Web of Science ®Google Scholar
• Taylor R. R., Weber D., Broccoli A. V., Winfield J. B. Stability of DNA/anti-DNA complexes. J. Immunol. 1979; 122: 115–120
   PubMed Web of Science ®Google Scholar
• Pisetsky D. S., Caster S. A. The B cell repertoire for autoantibodies: Frequency of precursor cells for anti-DNA antibodies. Cell. Immunol. 1982; 72: 294–305
   PubMed Web of Science ®Google Scholar
• Herzenberg L. A., Stall A., Labor P., Herzenberg L. The Ly-1 B cell lineage. Immunol. Rev. 1986; 93: 81–95
   PubMed Web of Science ®Google Scholar
• Casali P., Burastero S. E., Nakamura M., Inghirami G., Notkins A. L. Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1 + B-cell subsets. Science 1987; 236: 77–81
   PubMed Web of Science ®Google Scholar
• Monestier M., Manheimer-Lory A., Bellon B., Painter C., Dang H., Talal N., Zanetti M., Schwartz R., Pisetsky D., Kuppers R., Rose N., Brochier J., Klareskog L., Holmdahl R., Erlanger B., Alt F., Bona C. Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities. J. Clin. Invest. 1986; 78: 753–759
   PubMed Web of Science ®Google Scholar
• Hoch S., Schwaber J. Identification and sequence of the VH gene elements encoding a human anti-DNA antibody. J. Immunol. 1987; 139: 1689–1693
   PubMed Web of Science ®Google Scholar
• Kofler R., Dixon F. J., Theofilopoulos A. N. The genetic origin of autoantibodies. Immunology Today 1987; 8: 374–380
   PubMedGoogle Scholar
• Panosian-Sahakian N., Klotz J., Ebling F., Kronenberg M., Hahn B. H. Diversity of IjV gene segments found in anti-DNA antibodies from a single (NZB NZW)F, mouse. J. Immunol. 1989; 142
   PubMed Web of Science ®Google Scholar
• Monestier M., Bonin B., Migliorini P., Dang H., Datta S., Kuppers R., Rose N., Maurer P., Talal N., Bona C. Autoantibodies of various specificities encoded by genes from the VH J558 family bind to foreign antigens and share idiotopes of antibodies specific for self and foreign antigens. J. Exp. Med. 1987; 166: 1109–1124
   PubMed Web of Science ®Google Scholar
• Kofler R., Perlmutter R. M., Noonan D. J., Dixon F. J., Theofilopoulos A. N. Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism. J. Exp. Med. 1985; 162: 346–352
   PubMed Web of Science ®Google Scholar
• Kofler R., Noonan D. J., Levy D. E., Wilson M. C., Moller N. P. H., Dixon F. J., Theofilopoulos A. N. Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens. J. Exp. Med. 1985; 161: 805–811
   PubMed Web of Science ®Google Scholar
• Ando D. G., Sercarz E. E., Hahn B. H. Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model. J. Immunol. 1987; 138: 3185–3190
   PubMed Web of Science ®Google Scholar
• Wofsy D., Seaman W. E. Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4. J. Exp. Med. 1985; 161: 378–384
   PubMed Web of Science ®Google Scholar
• Mihara M., Ohsugi Y., Saito K., Miyai T., Togashi M., Ono S., Murakami S., Dobashi K., Hirayam F., Hamaoka T. Immunologic abnormality in NZB/NZW F1 mice. Thymus-independent occurrence of B cell abnormality and requirement for T cells in the development of autoimmune disease, as evidenced by an analysis of the athymic nude individuals. J. Immunol. 1988; 141: 85–90
   PubMed Web of Science ®Google Scholar
• Datta S. K., Patel H., Berry D. Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis. J. Exp. Med. 1987; 165: 1252–1268
   PubMed Web of Science ®Google Scholar
• Ando D. G., Secarz E. E., Hahn B. H. Helper T cells of the TH-2 subset accelerate autoantibody production and nephritis in NZB/NZW mice. Arthritis Rheum. 1988; 31: S41, abstract).
   Google Scholar
• Mosmann T. R., Cerwinski H. R., Bond M. W., Geidlin M. A., Coffman R. L. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986; 136: 1248–2352
   Web of Science ®Google Scholar
• Herron L. R., Coffman R. L., Kotzin B. L. Increased autoantibody production by NZB/NZW B cells in response to Interleukin 5. Arthritis Rheum., 31: S31, abstract)
   Google Scholar
• Kotzin B. L., Barr V. L., Palmer E. A large deletion within the T-cell receptor beta-chain gene complex in New Zealand White mice. Science 1985; 167: 171–174
   Google Scholar
• Fronek Z., Lentz D., Berliner N., Duby A. D., Klein K. A., Seidman J. G., Schur P. H. Systemic lupus erythematosus is not genetically linked to the beta chain of the T cell receptor. Arthritis Rheum. 1986; 29: 1023–1025
   PubMedGoogle Scholar
• Portanova J. P., Ebling F. M., Hammond W. S., Hahn B. H., Kotzin B. L. Allogeneic MHC antigen requirements for lupus-like autoantibody production and nephritis in murine graft-versus-host disease. J. Immunol. 1988; 141: 3370–3376
   PubMed Web of Science ®Google Scholar
• Boswell J. M., Yui M A, Endres S., Burt D. S., Kelley V. E. Novel and enhanced IL-1 gene expression in autoimmune mice with lupus. J. Immunol. 1988; 141: 118–124
   PubMed Web of Science ®Google Scholar