Combinatorial Libraries

References

• Tonegawa S. Somatic generation of antibody diversity. Nature 1983; 302: 575
   PubMed Web of Science ®Google Scholar
• Kabat E. A., Wu T. T., Reid-Miller M., Perry H. M., Gottesman K. S. Sequences of Proteins of Immunological Interest, 4th Ed. U.S. Dept. Health and Human Services, Washington, DC 1987
   Google Scholar
• Mullis K. B., Faloona F. A., Scharf S., Saiki R., Horn G., Erlich H. Specific enzymatic amplification of DNA in vitro: The polymerase chain reaction. Cold Spring Harb. Symp. Quant. Biol 1986; 51: 263–273
   PubMedGoogle Scholar
• Better M., Chang C. P., Robinson R. R., Horwitz A. H. Escherichia coli secretion of an active chimeric antibody fragment. Science 1988; 240: 1041–1043
   PubMed Web of Science ®Google Scholar
• Smith G. P. Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface. Science 1985; 228: 1315–1317
   PubMed Web of Science ®Google Scholar
• Huse W. D., Sastry L., Iverson S. A., Kang A. S., Alting-Mees M., Burton D. R., Benkovic S. J., Lerner R. A. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 1989; 246: 1275–1281
   PubMed Web of Science ®Google Scholar
• Larrick J. W., Danielsson L., Brenner C. A., Abrahamson M., Fry K. E., Borrebaeck C. A. K. Rapid cloning of rearranged immunoglobulin genes from human hybridoma cells using mixed primers and the polymerase chain reaction. Biochem. Biophys. Res. Commun 1989; 160: 1250–1256
   PubMed Web of Science ®Google Scholar
• Orlandi R., Gussow D. H., Jones P. T., Winter G. W. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA 1989; 86: 3833–3837
   PubMed Web of Science ®Google Scholar
• Sastry L., Alting-Mees M., Huse W. D., Short J. M., Sorge J. A., Hay B. N., Janda K. D., Benkovic S. J., Lerner R. A. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: Construction of a heavy chain variable region specific cDNA library. Proc. Nail. Acad. Sci. USA 1989; 86: 5728–5732
   PubMed Web of Science ®Google Scholar
• McCafferty J., Griffiths A. D., Winter G. W., Chiswell D. J. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 1990; 348: 552–553
   PubMed Web of Science ®Google Scholar
• Barbas C. E., III, Kang A. S., Lerner R. A., Benkovic S. J. Assembly of combinatorial antibody libraries on phage surfaces: The gene III site. Proc. Natl. Acad. Sci. USA 1991; 88: 7978–7982
   PubMed Web of Science ®Google Scholar
• Hoogenboom H. R., Griffiths A. D., Johnson K. S., Chiswell D. J., Hudson P., Winter G. W. Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res 1991; 19: 4133–4137
   PubMed Web of Science ®Google Scholar
• Stevens R. H., Macy E., Morrow C., Saxon A. Characterization of a circulating subpopulation of spontaneous antitetanus toxoid antibody producing B cells following in vivo booster immunization. J. Immunol 1979; 122: 2498–2504
   PubMed Web of Science ®Google Scholar
• Marks J. D., Tristrem M., Karpas A., Winter G. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes. Eur. J. Immunol 1991; 21: 985–991
   PubMed Web of Science ®Google Scholar
• Kang A. S., Burton D. R., Lerner R. A. Combinatorial immunoglobulin libraries in phage λ. Methods: Companion Methods Enzymol 1991; 2: 111–118
   Google Scholar
• Persson M. A. A., Caothien R., Burton D. R. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proc. Natl. Acad. Sci. USA 1991; 88: 2432–2436
   PubMed Web of Science ®Google Scholar
• Barbas C. F., Collet T. A., Roben R., Binley J., Amberg W., Hoekstra D., Cababa D., Jones T. M., Williamson A., Pilkington D., Haigwood N. L., Satterthwait A. C., Sanz I., Burton D. R. Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries. J. Mol. Biol 1992, in press
   Google Scholar
• Marks J. D., Hoogenboom H. R., Bonnert T. R., McCafferty J., Griffiths A. D., Winter G. W. Bypassing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol 1991; 222: 581–597
   PubMed Web of Science ®Google Scholar
• Gram H., Marconi L. -A., Barbas C. F., III, Collet T. A., Lerner R. A., Kang A. S. In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. Proc. Natl. Acad. Sci. USA 1992; 89: 3576–3580
   PubMed Web of Science ®Google Scholar
• Caton A. J., Koprowski H. Influenza virus hemagglutinin-specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor. Proc. Natl. Acad. Sci. USA 1990; 87: 6450–6454
   PubMedGoogle Scholar
• Proc. Natl. Acad. Sci. USA 1991; 88: 1590, correction
   Google Scholar
• Kang A. S., Barbas C. F., Janda K. D., Benkovic S. J., Lerner R. A. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proc. Natl. Acad. Sci. USA 1991; 88: 4363–4366
   PubMed Web of Science ®Google Scholar
• Burton D. R., Barbas C. E., III, Persson M. A. A., Koenig S., Chanock R. M., Lerner R. A. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc. Natl. Acad. Sci. USA 1991; 88: 10134–10137
   PubMed Web of Science ®Google Scholar
• Clackson T., Hoogenboom H. R., Griffiths A. D., Winter G. Making antibody fragments using phage display libraries. Nature 1991; 352: 624–628
   PubMed Web of Science ®Google Scholar
• Collet T. A., Roben R., O'Kennedy R., Barbas C. E., III, Burton D. R., Lerner R. A. A binary plasmid system for shuffling combinatorial antibody libraries. Proc. Natl. Acad. Sci. USA 1992; 89: 10026–10030
   PubMed Web of Science ®Google Scholar
• Isaacs J. D., Watts R. A., Hazleman B. L., Hale G., Keogan M. T., Cobbold S. R., Waldman H. Humanised monoclonal antibody therapy for rheumatoid arthritis. Lancet 1992; 340: 748–752
   PubMed Web of Science ®Google Scholar
• Barbas C. E., III, Björling E., Chiodi F., Dunlop N., Cababa D., Jones T. M., Zebedee S. L., Persson M. A. A., Nara P. L., Norrby E., Burton D. R. Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. Proc. Natl. Acad. Sci. USA 1992; 89: 9339–9343
   PubMed Web of Science ®Google Scholar
• Hinkula J., von Garrelts E., Lundin K., Holmberg V., Wigzell H., Sandstrom E., Wahren B., Persson M. A. A. Human monoclonal Fab molecules generated from a rgp-160 vaccinated HIV-1 seropositive individual neutralize the virus in vitro, manuscript in preparation. 1992
   Google Scholar
• Barbas C. E., Crowe J. E., Jr., Cababa D., Jones T. M., Zebedee S. L., Murphy B. R., Chanock R. M., Burton D. R. Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F. glycoprotein and neutralize infectivity. Proc. Natl. Acad. Sci. USA 1992; 89: 10164–10168
   PubMed Web of Science ®Google Scholar
• Hemming V. G., Prince G. A., London W. T., Baron P. A., Brown R., Chanock R. M. Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys. Antimicrob. Agents Chemother 1988; 32: 1269–1270
   PubMed Web of Science ®Google Scholar
• Mullinax R. L., Gross E. A., Amberg J. R., Hay B. N., Hogrefe H. H., Kubitz M. M., Greener A., Alting-Mees M., Ardourell D., Short J. M., Sorge J. A., Shopes B. Identification of human antibody fragment clones specific for tetanus toxoid in bacteriophage 1 immunoexpression library. Proc. Natl. Acad. Set. USA 1990; 87: 8095–8099
   PubMed Web of Science ®Google Scholar
• Zebedee S. L., Barbas C. E., III, Horn Y. -L., Caothien R. H., Graff R., DeGraw J., Pyati J., LaPolla R., Burton D. R., Lerner R. A., Thornton G. B. Human combinatorial antibody libraries to hepatitis B surface antigen. Proc. Natl. Acad. Sci. USA 1992; 89: 3175–3179
   PubMed Web of Science ®Google Scholar
• Portolana S., Seto P., Charzenbalk G. D., Nagayumi Y., MacLachlan S. M., Rapaport B. A human Fab fragment for thyroid peroxidase generated by cloning thyroid lymphocyte derived immunoglobulin genes in a bacteriophage lambda library. Biochem. Biophys. Res. Comm 1991; 179: 372–379
   PubMedGoogle Scholar
• Hexham J. M., Persson M. A.A., Pegg C., Burton D. R., Furmaniak J., Rees-Smith B. Cloning and expression of a human thyroglobulin autoantibody. Autoimmunity 1991; 11: 69–70
   PubMed Web of Science ®Google Scholar
• Larrick J. W., Danielsson L., Brenner C. A., Abrahamsson M., Fry K. E., Borrebeack C. A. K. Polymerase chain reaction using mixed primers: Cloning of human monoclonal variable region genes from single hybridoma cells. Bio/Technology 1989; 7: 934–938
   Web of Science ®Google Scholar
• Apatoff B. R., Latov N., Hoekstra D. M., Barbas C. E., Lerner R. A. Restricted utilization of immunoglobulin variable region genes in multiple sclerosis brain: Relation to autoimmunity. Communication to the 2nd Conference of Human Antibodies and Hybridomas, CambridgeUK, 1992
   Google Scholar
• Marks J. D., Griffiths A. D., Malmqvist M., Clackson T. P., Bye J. M., Winter G. By-passing immunization: Building high affinity human antibodies by chain shuffling. Bio/Technology 1992; 10: 779–783
   PubMed Web of Science ®Google Scholar
• Barbas C. E., III, Bain J. D., Hoekstra D. M., Lerner R. A. Semi-synthetic combinatorial antibody libraries: A chemical solution to the diversity problem. Proc. Natl. Acad. Sci. USA 1992; 89: 4457–4461
   PubMed Web of Science ®Google Scholar
• Springer T. Adhesion molecules of the immune system. Nature 1990; 346: 425–434
   PubMed Web of Science ®Google Scholar
• Wegner C. D., Gundel R. H., Reilly R., Haynes N., Letts L. G., Rothlein R. Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. Science 1990; 247: 456–459
   PubMed Web of Science ®Google Scholar
• Faustman D., Coe C. Prevention of xenograft rejection by masking donor HLA class I antigens. Science 1991; 252: 1700–1702
   PubMed Web of Science ®Google Scholar
• Lerner R. A., Benkovic S. J., Schultz P. At the crossroads of chemistry and immunology: Catalytic antibodies. Science 1991; 252: 659–667
   PubMed Web of Science ®Google Scholar
• Bebbington C. R. Expression of antibody genes in nonlymphoid mammalian cells. Methods: Companion Methods Enzymol 1991; 2: 136–145
   Google Scholar