Extrathymic Differentiation of a T Cell Bearing Invariant Vα14Jα281 TCR

References

• Allison J. P., Lanier L. L. Structure, function and serology of the T-cell antigen receptor complex. Annu. Rev. Immunol 1987; 5: 503
   PubMed Web of Science ®Google Scholar
• Bierer B. E., Sleckman B. F., Ratnofsky S. E., Burakoff S. J. The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu. Rev. Immunol 1989; 7: 579
   PubMed Web of Science ®Google Scholar
• Janeway C. A. J. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol 1992; 10: 645
   PubMed Web of Science ®Google Scholar
• Saito T., Germain R. The molecular basis of MHC-restricted antigen recognition by T cells. Intern. Rev. Immunol 1988; 3: 147
   PubMedGoogle Scholar
• Schwartz R. H. T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. Annu. Rev. Immunol 1985; 3: 237
   PubMed Web of Science ®Google Scholar
• Heber-Katz E., Schwartz R. H., Matis L. A., Hannum C., Fairwell T., Appella E., Hansburg D. Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation. J. Exp. Med 1982; 155: 1086
   Google Scholar
• De Talance A., Regnier D., Spinella S., Morisset J., Seman M. Origin of autoreactive T helper cells. I. Characterization of Thy-1+, Lyt−, L3T4− precursors in the spleen of normal mice. J. Immunol 1986; 137: 1101
   PubMedGoogle Scholar
• Morisset J., Trannoy E., De Talance A., Spinella S., Debré P., Godet P., Seman M. Genetics and strain distribution of concanavalin A-reactive Ly-2−, L3T4− peripheral precursors of autoreactive T cells. Eur. J. Immunol 1988; 18: 387
   Google Scholar
• Guidos C. J., Weissman I. L., Adkins B. Developmental potential of CD4−8− thymocytes. Peripheral progeny include mature CD4−8− T cells bearing αβ T cell receptor. J. Immunol 1989; 142: 3773
   Google Scholar
• Huang L., Crispe I. N. Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8− α/β T cells. J. Exp. Med 1992; 176: 699
   Google Scholar
• Sykes M. Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4−CD8− andαβ TCR+ NK1.1+ cells. J. Immunol 1990; 145: 3209
   PubMed Web of Science ®Google Scholar
• Kubota H., Okazaki H., Onuma M., Kano S., Hattori M., Minato N. CD3+4−8− αβ T cell population with biased T cell receptor V gene usage. Presence in bone marrow and possible involvement of IL-3 for their extrathymic development. J. Immunol 1992; 149: 1143
   Google Scholar
• Londei M., Verhoef A., De Berardinis P., Kissonerghis M., Grubeck-Loebenstein B., Feldmann M. Definition of a population of CD4−8− T cells that express the αβ T-cell receptor and respond to interleukins 2,3, and 4. Proc. Natl. Acad. Sci. USA 1989; 86: 8502
   PubMed Web of Science ®Google Scholar
• Shivakumar S., Tsokos G. C., Datta S. K. T cell receptor α/β expressing double-negative (CD4−/CD8−) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis. Immunol J 1989; 143: 103
   PubMed Web of Science ®Google Scholar
• Kusunoki Y., Hirai Y., Kyoizumi S., Akiyama M. Evidence for in vivo clonal proliferation of unique population of blood CD4−/CD8− T cells bearing T-cell receptor α and β chains in two normal men. Blood 1992; 79.: 2965
   PubMed Web of Science ®Google Scholar
• Porcelli S., Morita C. T., Brenner M. B. CD1b restricts the response of human CD4−8− T lymphocytes to a microbial antigen. Nature 1992; 360: 593
   PubMed Web of Science ®Google Scholar
• Porcelli S., Yockey C. E., Brenner M. B., Balk S. P. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4−8− α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med 1993; 178: 1
   PubMed Web of Science ®Google Scholar
• Dellabona R., Casorati G., Friedli B., Angman L., Sallusto E., Tunnacliffe A., Roosneek E., Lanzavecchia A. In vivo persistence of expanded clones specific for bacterial antigens within the human T cell receptor α/β CD4−8− subset. J. Exp. Med 1993; 177: 1763
   PubMed Web of Science ®Google Scholar
• von Boehmer H. The developmental biology of T lymphocytes. Annu. Rev. Immunol 1988; 6: 309
   PubMed Web of Science ®Google Scholar
• von Boehmer H. Developmental biology of T cells in T cell-receptor transgenic mice. Annu. Rev. Immunol 1990; 8: 531
   PubMedGoogle Scholar
• von Boehmer H., Kirberg J., Rocha B. An unusual lineage of α/β T cells that contains autoreactive cells. Exp J. Med 1991; 174: 1001
   PubMed Web of Science ®Google Scholar
• Andreu-Sánchez J. L., Moreno de Alborán I., Moarcos M. A. R., Sánchez-Movilla A., Martinez-A C., Kroemer G. Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice. J. Exp Med 1991; 173: 1323
   PubMedGoogle Scholar
• Robey E. A., Ramsdell E., Gordon J. W., Mamalaki C., Kioussis D., Youn H. J., Gottlieb P. D., Axel R., Fowlkes B. J. A self-reactive T cell population that is not subject to negative selection. Intl. Immunol 1992; 4: 969
   Google Scholar
• Palathumpat V., Dejbakhsh-Jones S., Holm B., Wang H., Liang O., Strober S. Studies of CD4− CD8− αβ bone marrow T cells with suppressor activity. J. Immunol 1992; 148: 373
   PubMed Web of Science ®Google Scholar
• Seki S., Abo T., Ohteki T., Sugiura K., Kumagai K. Unusual αβ-T cells expanded in autoimmune lpr, mice are probably a counterpart of normal T cells in the liver. J. Immunol 1991; 147: 1214
   Google Scholar
• Abo T., Ohteki T., Seki S., Koyamada N., Yoshikai Y., Masuda T., Rikiishi H., Kumagai K. The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. Exp J. Med 1991; 174: 417
   Google Scholar
• Kennedy J. D., Pierce C. W., Lake J. P. Extrathymic T cell maturation. Phenotypic analysis of T cell subsets in nude mice as a function of age. J. Immunol 1992; 148: 1620
   PubMedGoogle Scholar
• Seman M., Boudaly S., Roger T., Morisset I., Pham G. Autoreactive T cells in normal mice: unrestricted recognition of self peptides on dendritic cell I-A molecules by CD4−CD8− T cell receptor αβ+ T cell clones expressing Vβ8.1 gene segments. Eur. J. Immunol 1990; 20: 1265
   PubMedGoogle Scholar
• Porcelli S., Brenner M. B., Greenstein J. L., Balk S. R., Terhorst C., Bleicher P. A. Recognition of cluster of differentiation 1 antigens by human CD4−CD8− cytolytic T lymphocytes. Nature 1989; 341: 447
   PubMed Web of Science ®Google Scholar
• Brooks E. G., Wirt D. P., Goldblum R. M., Vaidya S., Asuncion M. T., Patterson J. C., Ware C. E., Klimpel G. R. Double-negative (CD4−CD8−) T cells with an α/β T cell receptor. Non-MHC-restricted cytolytic activity and lymphokine production. J. Immunol 1990; 144: 4507
   PubMed Web of Science ®Google Scholar
• Imai K., Kanno M., Kimoto H., Shigemoto K., Yamamoto S., Taniguchi M. Sequence and expression of transcripts of the T-cell antigen receptor α-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma. Proc. Natl. Acad. Sci. USA 1986; 83: 8708
   PubMed Web of Science ®Google Scholar
• Arden B., Klotz J. L., Siu G., Hood L. E. Diversity and structure of genes of the α family of mouse T-cell antigen receptor. Nature 1985; 316: 783
   PubMedGoogle Scholar
• Kronenberg M., Siu G., Hood L. E., Shastri N. The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu. Rev. Immunol 1986; 4: 529
   PubMed Web of Science ®Google Scholar
• Koseki H., Imai K., Nakayama F., Sado T., Moriwaki K., Taniguchi M. Homogenous junctional sequence of the V14+ T-cell antigen receptor α chain expanded in unprimed mice. Proc. Natl. Acad. Sci. USA 1990; 87: 5248
   Google Scholar
• Koseki H., Asano H., Inaba T., Miyashita N., Moriwaki K., Fischer Lindahl K., Mizutani Y., Imai K., Taniguchi M. Dominant expression of a distinctive V14+ T-cell antigen receptor a chain in mice. Proc. Natl. Acad. Sci. USA 1991; 88: 7518
   Google Scholar
• Koseki H., Imai K., Ichikawa T., Hayata I., Tanaguchi M. Predominant use of a particular α-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin. Intl. Immunol 1989; 1: 557
   Google Scholar
• Garman R. D., Ko J. -L., Vulpe C. D., Raulet D. H. T-cell receptor variable region gene usage in T-cell populations. Proc. Natl. Acad. Sci. USA 1986; 83: 3987
   Google Scholar
• Makino Y., Yamagata N., Sasho T., Adachi Y., Kanno R., Koseki H., Kanno M., Taniguchi M. Extrathymic development of Vα14-positive T cells. J. Exp. Med 1993; 177: 1399
   Google Scholar
• Ito T., Ishibashi K., Imai K., Koseki H., Kantake M., Ra C., Fernandez E., Saito T., Taniguchi M. Monoclonal antibody against murine T cell receptor Vα14 cross-reacts with human CD3-ε and detects disulfide-liked dimeric form. Intl. Immunol 1991; 3: 991
   Google Scholar
• Thomas M. L. The leukocyte common antigen family. Annu. Rev. Immunol 1989; 7: 339
   PubMed Web of Science ®Google Scholar
• Lefrancois L., Thomas M. L., Bevan M. J., Trowbridge I. S. Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200. J. Exp. Med 1986; 163: 1337
   PubMed Web of Science ®Google Scholar
• Cerottini J. -C., MacDonald H. R. The cellular basis of T-cell memory. Annu. Rev. Immunol 1989; 7: 77
   PubMed Web of Science ®Google Scholar
• Lynch E., Chaudhri G., Allan J. E., Doherty P. C., Ceredig R. Expression of Pgp-1 (or Ly24) by subpopulations of mouse thymocytes and activated peripheral T lymphocytes. Eur. J. Immunol 1987; 17: 137
   Google Scholar
• Hedrick S. M., Engel I., McElligott D. L., Fink P. J., Hsu M. -L., Hansburg D., Matis L. A. Selection of amino acid sequences in the beta chain of the T cell antigen receptor. Science 1988; 239: 1541
   PubMed Web of Science ®Google Scholar
• Roth M. E., Lacy M. J., McNeil L. K., Kranz D. M. Selection of variable-joining region combinations in the α chain of the T cell receptor. Science 1988; 241: 1354
   Google Scholar
• Fischer Lindahl K., Hausmann B. A new H-2,-linked class I gene whose expression depends on a maternally inherited factor. Nature 1983; 306: 383
   Google Scholar
• Richards S., Bucan M., Brorson K., Kiefer M. C., Hunt S. W., III, Lehrach H., Fischer Lindahl K. Genetic and molecular mapping of the Hmt, region of mouse. EMBO J 1989; 8: 3749
   PubMedGoogle Scholar
• Sumida T., Sado T., Kojima M., Ono K., Kamisaku H., Taniguchi M. I-J. as an idiotype of the recognition component of antigen-specific suppressor T-cell factor. Nature 1985; 316: 738
   Google Scholar
• Zijlstra M., Li E., Sajjadi F., Subramani S., Jaenisch R. Germ line transmission of a disrupted (β2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature 1989; 342: 435
   PubMed Web of Science ®Google Scholar
• Roman-Roman S., Ferradini L., Azocar J., Genevée C., Hercend T., Triebel F. Studies on the human T cell receptor α/β variable region genes. I.Identification of 7 additional Vα subfamilies and 14 Jα gene segments. Eur. J. Immunol 1991; 21: 927
   PubMedGoogle Scholar
• Crews S., Griffin J., Huang H., Calame K., Hood L. A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody. Cell 1981; 25: 59
   PubMed Web of Science ®Google Scholar
• Davis M. M., Bjorkman P. J. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334: 395
   PubMed Web of Science ®Google Scholar
• Okazaki K., Davis D. D., Sakano H. T cell receptor β gene sequences in the circular DNA of thymocyte nuclei: Direct evidence for intramolecular DNA deletion in V-D-J joining. Cell 1987; 49: 477
   PubMed Web of Science ®Google Scholar
• Fujimoto S., Yamagishi H. Isolation of an excision product of T-cell receptor α-chain gene rearrangement. Nature 1987; 327: 242
   PubMedGoogle Scholar
• Lieber M. R. Site-specific recombination in the immune system. FASEB J 1991; 5: 2934
   PubMedGoogle Scholar
• Roth D. B., Nakajima P. B., Menetski J. P., Bosma M. J., Gellert M. V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals. Cell 1992; 69: 41
   PubMed Web of Science ®Google Scholar
• Takeshita S., Toda M., Yamagishi H. Excision products of the T cell receptor gene support a progressive rearrangement model of the α/δ locus. EMBO J 1989; 8: 3261
   PubMed Web of Science ®Google Scholar
• Schatz D. G., Oettinger M. A., Baltimore D. The V(D)J recombination activating gene, RAG-1. Cell 1989; 59: 1035
   PubMed Web of Science ®Google Scholar
• Oettinger M. A., Schatz D. G., Gorka C., Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 1990; 248: 1517
   PubMed Web of Science ®Google Scholar
• Allison J. R., Havran W. L. The immunobiology of T cells with invariant γδ antigen receptors. Annu. Rev. Immunol 1991; 9: 679
   PubMed Web of Science ®Google Scholar
• Havran W. L., Chien Y. -H., Allison J. P. Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors. Science 1991; 252: 1430
   PubMed Web of Science ®Google Scholar
• Guy-Grand D., Cerf-Bensussan N., Malissen B., Malassis-Seris M., Briottet C., Vassalli P. Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: A role for the gut epithelium in T cell differentiation. J. Exp. Med 1991; 173: 471
   PubMed Web of Science ®Google Scholar
• Rocha B., Vassalli R., Guy-Grand D. The Vβ repertoire of mouse gut homodimeric α CD8+ intraepithelial T cell receptor α/β+ lymphocytes reveals a major extrathymic pathway of T cell differentiation. J. Exp. Med 1991; 173: 483
   PubMed Web of Science ®Google Scholar
• Sim G. -K., Augustin A. Dominantly inherited expression of BID, an invariant undiversified T cell receptor δ chain. Cell 1990; 61: 397
   Google Scholar
• Roths J. B., Murphy E. D., Eicher E. M. A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice. J. Exp. Med 1984; 159: 1
   PubMed Web of Science ®Google Scholar
• Cohen P. L., Eisenberg R. A. Lpr, and gld:, Single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol 1991; 9: 243
   PubMed Web of Science ®Google Scholar
• Andrews B. S., Eisenberg R. A., Theofilopoulos A. N., Izui S., Wilson C. B., McConahey P. J., Murphy E. D., Roths J. B., Dixon F. J. Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J. Exp. Med 1978; 148: 1198
   PubMed Web of Science ®Google Scholar