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Clinical Studies

Type of Renal Replacement Therapy and Residual Renal Function May Affect Prohepcidin and Hepcidin

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Pages 876-883 | Received 01 May 2009, Accepted 27 Jul 2009, Published online: 23 Dec 2009

References

  • Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276:7806–7810.
  • Krause A, Neitz S, Magert HJ Schyltz A, Forssmann WG, Schulz-Knappe P, Adermann L. LEAP-1, a novel highly disulfide-bonded human peptide exhibits antimicrobial activity. FEBS Lett. 2000;480:147–150.
  • Kulaksiz H, Gehrke SG, Janetzko A, Rost D, Bruckner T, Kallinowski B, Stremmel W. Prohepcidin: Expression and cell specific localization in the liver and its regulation in hereditary hemochromatosis, chronic renal insufficiency, and renal anaemia. Gut. 2004;53:735–743.
  • Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, Beaumont C, Kahn A, Vaulont S. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037–1044.
  • Gauldie J, Richards C, Harnish D, Lansdorp P, Baumann H. Interferon b2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci USA. 1987;84:7251–7255.
  • Moshage HJ, Janssen JA, Franssen JH, Hafkenscheid JC, Yap SH. Study of the molecular mechanisms of decreased liver synthesis of albumin in inflammation. J Clin Invest. 1987;79:1635–1641.
  • Taes YE, Wuyts B, Boelaert JR, De Vriese AS, Delanghe JR. Prohepcidin accumulates in renal insufficiency. Clin Chem Lab Med. 2004;42:387–389.
  • Allen DA, Breen C, Yaqoob MM, Macdougall IC. Inhibition of CFU-E colon formation in uremic patients with inflammatory disease. Role of IFN-gamma and TNF-alpha. J Investig Med. 1999;47:204–211.
  • Malyszko J, Malyszko JS, Pawlak K, Mysliwiec M. Hepcidin, iron status and renal function in chronic renal failure, kidney transplantation and hemodialysis. Am J Hematol. 2006;81:832–837.
  • Poole S, Bird TA, Selkirk S, Gaines-Das RE, Choudry Y, Stephenson SL, Kenny AJ, Saklatvaa J. Fate of injected interleukin 1 in rats: Sequestration and degradation in the kidney. Cytokine. 1990;2:416–422.
  • Panichi V, Migliori M, De Pietro S, Taccola D, Bianchi AM, Norpoth M, Metelli MR, Giovannini L, Tetta C, Palla R. C reactive protein in patients with chronic renal diseases. Ren Fail. 2001;23:551–562.
  • Stenvinkel P, Heimburger O, Wang T, Lindholm B, Bergstrom J, Elinder CG. High serum hyaluronan indicates poor survival in renal replacement therapy. Am J Kidney Dis. 1999;34:1083–1088.
  • Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003;101:2461–2463.
  • Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271–1276.
  • Chung SH, Heimburger O, Stenvinkel P, Bergstrom J, Lindholm B. Association between inflammation and changes in residual renal function and peritoneal transport rate during the first year of dialysis. Nephrol Dial Transplant. 2001;16:2240–2245.
  • Pecoits-Filho R, Heimburger O, Barany P, Suliman M. Associations between circulating inflammatory markers and residual renal function in CRF patients. Am J Kidney Dis. 2003;41:1212–1218.
  • Malyszko J, Malyszko JS, Hryszko T, Pawlak K, Mysliwiec M. Is hepcidin a link between anemia, inflammation and liver function in hemodialyzed patients?. Am J Nephrol. 2005;25:586–590.
  • Tomosugi N, Kawabata H, Wakatabe R, Detection of serum hepcidin in renal failure and inflammation by using ProteinChip System. Blood. 2006;108:1381–1387.
  • Ashby DR, Gale DP, Busbridge M, Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease. Kidney Int. 2009 Feb 11 [E-pub ahead of print].
  • Kato A, Tsuji T, Luo J, Sakao Y, Yasuda H, Hishida A. Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients. Am J Nephrol. 2008;28:115–121.
  • Roe MA, Spinks C, Heath AL, Harvey LJ, Foxall R, Wimperis J, Wolf C, Fairweather-Tait SJ. Serum prohepcidin concentration: No association with iron absorption in healthy men; and no relationship with iron status in men carrying HFE mutations, hereditary hemochromatosis patients undergoing phlebotomy treatment, or pregnant women. Br J Nutr. 2007;97:544–549.
  • Murphy AT, Witcher DR, Luan P, Wroblewski VJ. Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry. Blood. 2007;110:1048–1054.
  • Kobold U, Dulffer T, Dangl M, Escherich A, Kubbies M, Röddiger R, Wright JA. Quantification of hepcidin-25 in human serum by isotope dilution micro-HPLC-tandem mass spectrometry. Clin Chem. 2008;54:1584–1586.
  • Li H, Rose MJ, Tran L, Zhang J, Miranda LP, James CA, Sasu BJ. Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS. J Pharmacol Toxicol Methods. 2009;59:171–180.
  • Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. Immunoassay for human serum hepcidin. Blood. 2008;112:4292–4297.
  • Koliaraki V, Marinou M, Vassilakopoulos TP, Vavourakis E, Tsochatzis E, Pangalis GA, Papatheodoridis G, Stamoulakatou A, Swinkels DW, Papanikolaou G, Mamalaki A. A novel immunological assay for hepcidin quantification in human serum. PLoS ONE. 2009;4:e4581.
  • Grebenchtchikov N, Geurts-Moespot AJ, Kroot JJ, den Heijer M, Tjalsma H, Swinkels DW, Sweep FG. High-sensitive radioimmunoassay for human serum hepcidin. Br J Haematol 2009 Jun 3. PubMed PMID: 19500086 [E-pub ahead of print].
  • Malyszko J. Hepcidin assay-ironing out the details. Clin J Am Soc Nephrol. 2009;4:1015–1016.

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