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Uremia Investigation Volume 9, 1985 - Issue 2
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Original Article

Urinary Kallikrein Activity is Not Altered in Human Essential Hypertension

B. M. Simonetti Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
A. Pierucci Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
F. Taggi Laboratory of Epidemiology and Biostatistics National Institute of Health, Rome, Italy
,
S. Morabito Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
S. Vastano Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
S. Marchetti Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
R. L. Putini Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
,
G. Stirati Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
&
G. A. Cinotti Department of Internal Medicine, Division of Nephrology, University of Rome, La Sapienza, Italy
 show all
Pages 189-193 | Published online: 07 Jul 2009

References

  • Marin-Grez M. Multihormonal regulation of renal kallikrein. Biochem Pharmacol 1982; 31: 3941
  • Elliot A H, Nuzum F R. The urinary excretion of a depressor substance (kallikrein of Frey and Kraut) in arterial hypertension. Endocrinology 1934; 18: 462
  • Margolius H S, Horwitz D, Pisano J J, Keiser H R. Relationships among urinary kallikrein, mineralocorticoids and human hypertensive disease. Fed Proc 1976; 35: 203
  • Lechi A, Covi G, Lechi C, Corgnati A, Arosio E, Zatti M, Scuro L A. Urinary kallikrein excretion and plasma renin activity in patients with essential hypertension and primary aldosteronism. Clin Sci Mol Med 1979; 55: 51
  • Weber P C, Scherer B, Held E, Siess W, Stoffel H. Urinary prostaglandins and kallikrein in essential hypertension. Clin Sci 1979; 57: 259s
  • Lawton W J, Fitz A E. Abnormal urinary kallikrein in hypertension is not related to aldosterone or plasma renin activity. Hypertension 1980; 2: 787
  • Holland O B, Chud J M, Braunstein H. Urinary kallikrein excretion in essential and mineralocorticoid hypertension. J Clin Invest 1980; 65: 347
  • Koolen M I, Daha M R, Frolich M, Van Es L A, Van Brummelen P. Direct and indirect measurement of urinary kallikrein excretion in patients with essential hypertension and normotensives: Relation to age and plasma renin activity and aldosterone levels. Eur J Clin Invest 1984; 14: 171
  • Pierucci A, Simonetti B M, Pugliese F, Manzi M, Mene P, Stirati G, Cinotti G A. Kallikrein-kinin system involvement in chronic glomerular disease. Proceedings of the European Dialysis and Transplant Association-European Renal Association., London, 1985, AM Davison, PJ Guillou. Brussels, Bailliere Tindall, 1057–1061
  • Simonetti B M, Pierucci A, Cinotti G A, Marino A, D'Ascenzo G. Microdetermination of kallikrein-like arginine esterases in the urine. Ann Chim 1979; 69: 577
  • Haber E, Koerner T, Page B, Kliman B, Purnode A. Application of a radioimmunoassay for angiotensin I to the physiologic measurement of plasma renin activity in normal human subjects. J Clin Endocr 1969; 29: 1349
  • Levinsky N G. The renal kallikrein-kinin system. Circ Res 1979; 44: 441
  • Shimamoto K, Chao J, Margolius H S. The radioimmunoassay of human urinary kallikrein and comparisons with kallikrein activity measurements. J Clin Endocr Metab 1980; 51: 840

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