The Effects of the Iodinated X-Ray Contrast Media Iodixanol, Iohexol, Iopromide, and Ioversol on the Rat Kidney Epithelial Cell Line NRK 52-E

REFERENCEs

• Rihal CS, Textor SC, Grill DE, Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation. 2002;105:2259–2264.
   PubMed Web of Science ®Google Scholar
• Waybill MM, Waybill PN. Contrast media-induced nephrotoxicity: Identification of patients at risk and algorithms for prevention. J Vasc Interv Radiol. 2001;12:3–9.
   PubMed Web of Science ®Google Scholar
• Persson PB. Contrast-induced nephropathy. Eur Radiol. 2005;15(Suppl. 4):D65–D69.
   Google Scholar
• Morcos SK. Contrast media-induced nephrotoxicity – Questions and answers. Br J Radiol. 1998;71:357–365.
   PubMed Web of Science ®Google Scholar
• Persson PB, Tepel M. Contrast medium-induced nephropathy: The pathophysiology. Kidney Int Suppl. 2006;69:S8–S10.
   Web of Science ®Google Scholar
• Tumlin J, Stacul F, Adam A, Pathophysiology of contrast-induced nephropathy. Am J Cardiol. 2006;98:14K–20K.
   PubMed Web of Science ®Google Scholar
• Mehran R, Nikolsky E. Contrast-induced nephropathy: Definition, epidemiology, and patients at risk. Kidney Int Suppl. 2006;100:S11–S15.
   Web of Science ®Google Scholar
• Haller C, Hizoh I. The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro. Invest Radiol. 2004;39:149–154.
   PubMed Web of Science ®Google Scholar
• Duan S, Zhou X, Liu F, Comparative cytotoxicity of high-osmolar and low-osmolar contrast media on HKCs in vitro. J Nephrol. 2006;19:717–724.
   PubMed Web of Science ®Google Scholar
• Haller C, Schick CS, Zorn M, Kubler W. Cytotoxicity of radiocontrast agents on polarized renal epithelial cell monolayers. Cardiovasc Res. 1997;33:655–665.
   Google Scholar
• Hizoh I, Strater J, Schick CS, Kubler W, Haller C. Radiocontrast-induced DNA fragmentation of renal tubular cells in vitro: Role of hypertonicity. Nephrol Dial Transplant. 1998;13:911–918.
   PubMed Web of Science ®Google Scholar
• Davidson C, Stacul F, McCullough PA, Contrast medium use. Am J Cardiol. 2006;98:42K–58K.
   PubMed Web of Science ®Google Scholar
• Morcos SK. Contrast media induced nephrotoxicity. In: Dawson P, Cosgrove DO, Grainger RG, eds. Textbook of Contrast Media. Oxford, UK: Isis Medical Media; 1999:135–148.
   Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55–63.
   PubMed Web of Science ®Google Scholar
• Bursch W, Taper HS, Lauer B, Schulte-Hermann R. Quantitative histological and histochemical studies on the occurrence and stages of controlled cell death (apoptosis) during regression of rat liver hyperplasia. Virchows Arch B Cell Pathol Incl Mol Pathol. 1985;50:153–166.
   Google Scholar
• Levin S. Apoptosis, necrosis, or oncosis: What is your diagnosis? A report from the Cell Death Nomenclature Committee of the Society of Toxicologic Pathologists. Toxicol Sci. 1998;41:155–156.
   PubMed Web of Science ®Google Scholar
• Levin S, Bucci TJ, Cohen SM, The nomenclature of cell death: Recommendations of an ad hoc Committee of the Society of Toxicologic Pathologists. Toxicol Pathol. 1999;27:484–490.
   PubMed Web of Science ®Google Scholar
• Mohr U. Commentary: Comments on the cell death nomenclature recommendations of the Society of Toxicologic Pathologists. Toxicol Pathol. 1999;27:497.
   Google Scholar
• Stephens LC, Ang KK, Schultheiss TE, Milas L, Meyn RE. Apoptosis in irradiated murine tumors. Radiat Res. 1991;127:308–316.
   PubMed Web of Science ®Google Scholar
• Rickards D, Jakobsen JA, Klaveness AJ, Kjaersgaard P. Delayed CT of the kidneys after iopentol (Imagopaque 350) injection in patients with normal renal function. An assessment of the gradual decrease in opacification over 32 h after injection. Eur Radiol. 1997;7(Suppl. 4):S149–S151.
   Google Scholar
• Heinrich MC, Kuhlmann MK, Grgic A, Heckmann M, Kramann B, Uder M. Cytotoxic effects of ionic high-osmolar, nonionic monomeric, and nonionic iso-osmolar dimeric iodinated contrast media on renal tubular cells in vitro. Radiology. 2005;235:843–849.
   PubMed Web of Science ®Google Scholar
• Wasaki M, Sugimoto J, Shirota K. Glucose alters the susceptibility of mesangial cells to contrast media. Invest Radiol. 2001;36:355–362.
   PubMed Web of Science ®Google Scholar
• Katzberg RW. Urography into the 21st century: New contrast media, renal handling, imaging characteristics, and nephrotoxicity. Radiology. 1997;204:297–312.
   PubMed Web of Science ®Google Scholar
• Spataro RF, Fischer HW, Boylan L. Urography with low-osmolality contrast media: Comparative urinary excretion of Iopamidol, Hexabrix, and diatrizoate. Invest Radiol. 1982; 17:494–500.
   Google Scholar
• Berg K, Skarra S, Bruvold M, Brurok H, Karlsson JO, Jynge P. Iodinated radiographic contrast media possess antioxidant properties in vitro. Acta Radiol. 2005;46:815–822.
   PubMed Web of Science ®Google Scholar
• Andersen KJ, Christensen EI, Vik H. Effects of iodinated x-ray contrast media on renal epithelial cells in culture. Invest Radiol. 1994;29:955–962.
   PubMed Web of Science ®Google Scholar
• Hardiek K, Katholi RE, Ramkumar V, Deitrick C. Proximal tubule cell response to radiographic contrast media. Am J Physiol Renal Physiol. 2001;280:F61–F70.
   PubMed Web of Science ®Google Scholar
• Heinrich MC, Kuhlmann MK, Kohlbacher S, Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: In vitro study. Radiology. 2007;242:425–434.
   PubMed Web of Science ®Google Scholar
• Schick CS, Haller C. Comparative cytotoxicity of ionic and non-ionic radiocontrast agents on MDCK cell monolayers in vitro. Nephrol Dial Transplant. 1999;14:342–347.
   Google Scholar
• Schick CS, Bangert R, Kubler W, Haller C. Ionic radiocontrast media disrupt intercellular contacts via an extracellular calcium-independent mechanism. Exp Nephrol. 2002;10:209–215.
   Google Scholar
• Dobrota M, Powell CJ, Holtz E, Wallin A, Vik H. Biochemical and morphological effects of contrast media on the kidney. Acta Radiol Suppl. 1995;399:196–203.
   Google Scholar
• Nordby A, Tvedt KE, Halgunset J, Kopstad G, Haugen OA. Incorporation of contrast media in cultured cells. Invest Radiol. 1989;24:703–710.
   Google Scholar
• Kjeken R, Mousavi SA, Brech A, Gjoen T, Berg T. Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells. Cell Tissue Res. 2001;304:221–230.
   Google Scholar
• Skotland T, Grant D. In vitro cytotoxic effects of iodinated contrast media on a renal tubular cell line. Radiology. 2006;238:759–760.
   Google Scholar
• Heinrich M, Scheer M, Heckmann M, Bautz W, Uder M. Reversibility and time-dependency of contrast medium induced inhibition of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) conversion in renal proximal tubular cells in vitro: Comparison of a monomeric and a dimeric nonionic iodinated contrast medium. Invest Radiol. 2007;42:732–738.
   Google Scholar
• Itoh Y, Yano T, Sendo T, Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury. Kidney Int. 2006;69:288–297.
   PubMed Web of Science ®Google Scholar
• Romano G, Briguori C, Quintavalle C, Contrast agents and renal cell apoptosis. Eur Heart J. 2008; 29:2569–2576.
   PubMed Web of Science ®Google Scholar