Augmenter of Liver Regeneration Attenuates Tubular Cell Apoptosis in Acute Kidney Injury in Rats: The Possible Mechanisms

REFERENCES

• Ostermann M, Chang RW. Acute kidney injury in the intensive care unit according to RIFLE. Crit Care Med. 2007;35:1837–1843.
   PubMed Web of Science ®Google Scholar
• Coca SG, Yusuf B, Shlipak MG, Garg AX, Parikh CR. Long-term risk of mortality and other adverse outcomes after acute kidney injury: A systematic review and meta-analysis. Am J Kidney Dis. 2009;53:961–973.
   PubMed Web of Science ®Google Scholar
• Racusen LC, Fivush BA, Li YL, Slatnik I, Solez K. Dissociation of tubular cell detachment and tubular cell death in clinical and experimental “acute tubular necrosis”. Lab Invest. 1991;64: 546–556.
   PubMed Web of Science ®Google Scholar
• Ueda N, Shah SV. Tubular cell damage in acute renal failure — apoptosis, necrosis, or both. Nephrol Dial Transplant. 2000;15:318–323.
   PubMed Web of Science ®Google Scholar
• Safirstein RL. Acute renal failure: From renal physiology to the renal transcriptome. Kidney Int Suppl. 2004;91:S62–S66.
   PubMedGoogle Scholar
• Han KH, Kim HY, Croker BP, . Effects of ischemia-reperfusion injury on renal ammonia metabolism and the collecting duct. Am J Physiol Renal Physiol. 2007;293:F1342–F1354.
   PubMed Web of Science ®Google Scholar
• Srichai MB, Hao C, Davis L, Golovin A, . Apoptosis of the thick ascending limb results in acute kidney injury. J Am Soc Nephrol. 2008;19:1538–1546.
   PubMed Web of Science ®Google Scholar
• Bonegio R, Lieberthal W. Role of apoptosis in the pathogenesis of acute renal failure. Curr Opin Nephrol Hypertens. 2002;11: 301–308.
   PubMed Web of Science ®Google Scholar
• Dai C, Yang J, Liu Y. Single injection of naked plasmid encoding hepatocyte growth factor prevents cell death and ameliorates acute renal failure in mice. J Am Soc Nephrol. 2002;13:411–422.
   PubMed Web of Science ®Google Scholar
• Jo SK, Yun SY, Chang KH, . Alpha-MSH decreases apoptosis in ischemic acute renal failure in rats: Possible mechanism of this beneficial effect. Nephrol Dial Transplant. 2001;16: 1583–1591.
   PubMed Web of Science ®Google Scholar
• Vesey DA, Cheung C, Pat B, Endre Z, Gobé G, Johnson DW. Erythropoietin protects against ischemic acute renal injury. Nephrol Dial Transplant. 2004;19:348–355.
   PubMed Web of Science ®Google Scholar
• Spandou E, Tsouchnikas I, Karkavelas G, . Erythropoietin attenuates renal injury in experimental acute renal failure ischemic/reperfusion model. Nephrol Dial Transplant. 2006;21:330–336.
   PubMed Web of Science ®Google Scholar
• Menke J, Iwata Y, Rabacal WA, . CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice. J Clin Invest. 2009;119:2330–2342.
   PubMed Web of Science ®Google Scholar
• Kim YS, Jung MH, Choi MY, . Glutamine attenuates tubular cell apoptosis in acute kidney injury via inhibition of the c-Jun N-terminal kinase phosphorylation of 14-3-3. Crit Care Med. 2009;37:2033–2044.
   PubMed Web of Science ®Google Scholar
• Aravindan N, Aravindan S, Riedel BJ, Wang HR, Shaw AD. Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure. Ren Fail. 2007;29:399–407.
   PubMed Web of Science ®Google Scholar
• Huber JM, Tagwerker A, Heininger D, Mayer G, Rosenkranz AR, Eller K. The proteasome inhibitor bortezomib aggravates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2009;297:F451–F460.
   PubMed Web of Science ®Google Scholar
• Lieberthal W, Fuhro R, Andry CC, . Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol. 2001;281:F693–F706.
   PubMed Web of Science ®Google Scholar
• Rana A, Sathyanarayana P, Lieberthal W. Role of apoptosis of renal tubular cells in acute renal failure: Therapeutic implications. Apoptosis. 2001;6:83–102.
   PubMed Web of Science ®Google Scholar
• Hagiya M, Francavilla A, Polimeno L, . Cloning and sequence analysis of the rat augmenter of liver regeneration (ALR) gene: Expression of biologically active recombinant ALR and demonstration of tissue distribution. Proc Natl Acad Sci USA. 1994;91:8142–8146.
   PubMed Web of Science ®Google Scholar
• Zhang LM, Liu DW, Liu JB, . Effect of naked eukaryotic expression plasmid encoding rat augmenter of liver regeneration on acute hepatic injury and hepatic failure in rats. World J Gastroenterol. 2005;11:3680–3685.
   PubMed Web of Science ®Google Scholar
• Tanigawa K, Sakaida I, Masuhara M, Hagiya M, Okita K. Augmenter of liver regeneration (ALR) may promote liver regeneration by reducing natural killer (NK) cell activity in human liver diseases. J Gastroenterol. 2000;35:112–119.
   PubMed Web of Science ®Google Scholar
• Gao CF, Zhou FG, Wang H, Huang YF, Ji Q, Chen J. Genetic recombinant expression and characterization of human augmenter of liver regeneration. Dig Dis Sci. 2009;54:530–537.
   PubMed Web of Science ®Google Scholar
• Thirunavukkarasu C, Wang LF, Harvey SA, . Augmenter of liver regeneration: An important intracellular survival factor for hepatocytes. J Hepatol. 2008;48:578–588.
   PubMed Web of Science ®Google Scholar
• Ilowski M, Kleespies A, de Toni EN, . Augmenter of liver regeneration (ALR) protects human hepatocytes against apoptosis. Biochem Biophys Res Commun. 2011;404:148–152.
   PubMed Web of Science ®Google Scholar
• Cao Y, Fu YL, Yu M, . Human augmenter of liver regeneration is important for hepatoma cell viability and resistance to radiation-induced oxidative stress. Free Radic Biol Med. 2009;47:1057–1066.
   PubMed Web of Science ®Google Scholar
• Lorenzo P, Barbara P, Thomas L, . Protective effect of augmenter of liver regeneration on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells. Free Radic Res. 2009;43:865–875.
   PubMed Web of Science ®Google Scholar
• Liao XH, Zhang L, Tang XP, Liu Q, Sun H. Expression of augmenter of liver regeneration in rats with gentamicin-induced acute renal failure and its protective effect on kidney. Ren Fail. 2009;31:946–955.
   PubMed Web of Science ®Google Scholar
• Liao XH, Zhang L, Liu Q, Sun H, Peng CM, Guo H. Augmenter of liver regeneration protects kidneys from ischemia/reperfusion injury in rats. Nephrol Dial Transplant. 2010;25:2921–2929.
   PubMed Web of Science ®Google Scholar
• Liao XH, Zhang L, Liu Q, . Effect of recombinant rat augmenter of liver regeneration on proliferation and apoptosis of renal tubular cells. Chin J Nephrol. 2005;21:747–751.
   Google Scholar
• Liu Q, Yu HF, Sun H, Ma HF. Expression of human augmenter of liver regeneration in Pichia pastoris yeast and its bioactivity in vitro. World J Gastroenterol. 2004;10:3188–3190.
   PubMed Web of Science ®Google Scholar
• Pawlowski R, Jura J. ALR and liver regeneration. Mol Cell Biochem. 2006;288:159–169.
   PubMed Web of Science ®Google Scholar
• Daithankar VN, Farrell SR, Thorpe C. Augmenter of liver regeneration: Substrate specificity of a flavin-dependent oxidoreductase from the mitochondrial intermembrane space. Biochemistry. 2009;48:4828–4837.
   PubMed Web of Science ®Google Scholar
• Ilowski M, Putz C, Weiss TS, . Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner. Biochem Biophys Res Commun. 2010;394:915–920.
   PubMed Web of Science ®Google Scholar
• Yang B, Elias JE, Bloxham M, Nicholson ML. Synthetic small interfering RNA down-regulates caspase-3 and affects apoptosis, IL-1 β, and viability of porcine proximal tubular cells. J Cell Biochem. 2011;112:1337–1347.
   PubMed Web of Science ®Google Scholar
• Yang B, Hosgood SA, Nicholson ML. Naked small interfering RNA of caspase-3 in preservation solution and autologous blood perfusate protects isolated ischemic porcine kidneys. Transplantation. 2011;91:501–507.
   PubMed Web of Science ®Google Scholar
• Shu D, Qing Y, Tong Q, . Deltonin isolated from Dioscorea zingiberensis inhibits cancer cell growth through inducing mitochondrial apoptosis and suppressing Akt and Mitogen activated protein kinase signals. Biol Pharm Bull. 2011;34:1231–1239.
   PubMed Web of Science ®Google Scholar
• Chen NG, Lu CC, Lin YH, . Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: Roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways. Oncol Rep. 2011;26:939–947.
   PubMed Web of Science ®Google Scholar
• Alaimo A, Gorojod RM, Kotler ML. The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells. Neurochem Int. 2011;59:297–308.
   PubMed Web of Science ®Google Scholar
• Zakeri Z, Lockshin RA. Cell death: History and future. Adv Exp Med Biol. 2008;615:1–11.
   PubMed Web of Science ®Google Scholar
• Johnson DW, Pat B, Vesey DA, Guan Z, Endre Z, Gobe GC. Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failure. Kidney Int. 2006;69:1806–1813.
   PubMed Web of Science ®Google Scholar
• Stiles BL. PI-3-K and AKT: Onto the mitochondria. Adv Drug Deliv Rev. 2009; 61(14):1276–1282.
   PubMed Web of Science ®Google Scholar
• Franke T, Kaplan D, Cantley L. PI3K: Downstream AKTion blocks apoptosis. Cell. 1997;88:435–437.
   PubMed Web of Science ®Google Scholar
• Liu Y. Hepatocyte growth factor promotes renal epithelial cell survival by dual mechanisms. Am J Physiol. 1999;277: F624–F633.
   PubMed Web of Science ®Google Scholar
• Levine AJ, Hu W, The FZ. P53 pathway: What questions remain to be explored? Cell Death and Differentiation. 2006;13: 1027–1036.
   PubMed Web of Science ®Google Scholar
• Haupt S, Berger M, Goldberg Z, Haupt Y. Apoptosis – the p53 network. J Cell Sci. 2003;116:4077–4085.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xiong Y. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation. Science. 2001;292:1910–1915.
   PubMed Web of Science ®Google Scholar
• Zhang H, Hile KL, Asanuma H, . IL-18 mediates proapoptotic signaling in renal tubular cells through a Fas ligand-dependent mechanism. Am J Physiol Renal Physiol. 2011;301:F171–F178.
   PubMed Web of Science ®Google Scholar
• Lu CY, Hartono J, Senitko M, Chen JL. The inflammatory response to ischemic acute kidney injury: A result of the “right stuff” in the “wrong place”? Curr Opin Nephrol Hypertens. 2007;16:83–89.
   PubMed Web of Science ®Google Scholar