Advanced search
Publication Cover
Renal Failure Volume 34, 2012 - Issue 10
Submit an article Journal homepage
686
Views
8
CrossRef citations to date
0
Altmetric
Clinical Study

Global DNA Methylation Not Increased in Chronic Hemodialysis Patients: A Case–Control Study

Chiao-Ying HsuSchool of Medicine, Chang Gung University, Taoyuan, Taiwan;Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan
,
Chiao-Yin SunSchool of Medicine, Chang Gung University, Taoyuan, Taiwan;Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan
,
Chin-Chan LeeSchool of Medicine, Chang Gung University, Taoyuan, Taiwan;Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan
,
I-Wen WuSchool of Medicine, Chang Gung University, Taoyuan, Taiwan;Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan
,
Heng-Jung HsuSchool of Medicine, Chang Gung University, Taoyuan, Taiwan;Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan
&
Mai-Szu WuDivision of Nephrology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan;Department of Internal Medicine, School of Medicine, Taipei Medical University, Taipei, TaiwanCorrespondence[email protected]
Pages 1195-1199 | Received 03 May 2012, Accepted 14 Aug 2012, Published online: 01 Oct 2012

REFERENCES

  • Hwang SJ, Tsai JC, Chen HC. Epidemiology, impact and preventive care of chronic kidney disease in Taiwan. Nephrology. 2010;15(Suppl 2):3–9.
  • Yavuz A, Tetta C, Ersoy FF, . Uremic toxins: A new focus on an old subject. Semin Dial. 2005;18:203–211.
  • Ayodele OE, Alebiosu CO. Burden of chronic kidney disease: An international perspective. Adv Chronic Kidney Dis. 2010; 17:215–224.
  • Murr R. Interplay between different epigenetic modifications and mechanisms. Adv Genet. 2010;70:101–141.
  • van Vliet J, Oates NA, Whitelaw E. Epigenetic mechanisms in the context of complex diseases. Cell Mol Life Sci. 2007; 64:1531–1538.
  • Calvanese V, Lara E, Kahn A, Fraga MF. The role of epigenetics in aging and age-related diseases. Aging Res Rev. 2009;8:268–276.
  • Turek-Plewa J, Jagodziński PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett. 2005;10:631–647.
  • Fandy TE. Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases. Curr Med Chem. 2009;16:2075–2085.
  • Pan Y, Sawalha AH. Epigenetic regulation and the pathogenesis of systemic lupus erythematosus. Transl Res. 2009;153:4–10.
  • Ingrosso D, Cimmino A, Perna AF, . Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinemia in patients with uremia. Lancet. 2003;361:1693–1699.
  • Ingrosso D, Perna AF. Epigenetics in hyperhomocysteinemic states. A special focus on uremia. Biochim Biophys Acta. 2009;1790:892–899.
  • Castro R, Rivera I, Struys EA, . Increased homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease. Clin Chem. 2003;49:1292–1296.
  • Nanayakkara PW, Kiefte-de Jong JC, Stehouwer CD, . Association between global leukocyte DNA methylation, renal function, carotid intima-media thickness and plasma homocysteine in patients with stage 2–4 chronic kidney disease. Nephrol Dial Transplant. 2008;23:2586–2592.
  • Stenvinkel P, Karimi M, Johansson S, . Impact of inflammation on epigenetic DNA methylation—a novel risk factor for cardiovascular disease? J Intern Med. 2007;261:488–499.
  • Wu IW, Hsu KH, Lee CC, p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease. Nephrol Dial Transplant. 2011;26:938–947.
  • Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Rosa-Leyva M, Vilardell-Tarrés M. Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. Immunology. 2008;124:339–347.
  • Zhao M, Gao F, Wu X, Tang J, Lu Q. Abnormal DNA methylation in peripheral blood mononuclear cells from patients with vitiligo. Br J Dermatol. 2010;163:736–742.
  • Hodge DR, Xiao W, Clausen PA, . Interleukin-6 regulation of the human DNA metyltransferase (HDNMT) gene in human erythroleukemia cells. J Biol Chem. 2001;276: 39508–39511.
  • Montes de Oca A, Madueño JA, Martinez-Moreno JM, . High-phosphate-induced calcification is related to SM22α promoter methylation in vascular smooth muscle cells. J Bone Miner Res. 2010;25:1996–2005.
  • Kaye M. The anemia associated with renal disease. J Lab Clin Med. 1958;52:83–100.
  • Ting AH, Jair KW, Schuebel KE, Baylin SB. Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation. Cancer Res. 2006;66:729–735.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.