585
Views
5
CrossRef citations to date
0
Altmetric
Laboratory Study

All-Trans Retinoic Acid Attenuates the Renal Interstitial Fibrosis Lesion in Rats but Not By Transforming Growth Factor-β1/Smad3 Signaling Pathway

, , , , &
Pages 262-267 | Received 07 Mar 2012, Accepted 16 Oct 2012, Published online: 26 Nov 2012

REFERENCES

  • Thatcher JE, Zelter A, Isoherranen N. The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid. Biochem Pharmacol. 2010;80:903–912.
  • Napoli JL. Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta. 2012;1821:152–167.
  • Mauney JR, Ramachandran A, Yu RN, Daley GQ, Adam RM, Estrada CR. All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms. PLoS One. 2010;5:e11513.
  • Kishimoto K, Kinoshita K, Hino S, . Therapeutic effect of retinoic acid on unilateral ureteral obstruction model. Nephron Exp Nephrol. 2011;118:e69–e78.
  • Tabata C, Tabata R, Nakano T. The calpain inhibitor copeptin prevents bleomycin-induced pulmonary fibrosis in mice. Clin Exp Immunol. 2010;162:560–567.
  • Wang H, Dan Z, Jiang H. Effect of all-trans retinoic acid on liver fibrosis induced by common bile duct ligation in rats. J Huazhong Univ Sci Technolog Med Sci. 2008;28:553–557.
  • Kawakatsu M, Kanno S, Gui T, . Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing. Exp Mol Pathol. 2011;90:107–115.
  • Chen HY, Huang XR, Wang W, . The protective role of Smad7 in diabetic kidney disease: Mechanism and therapeutic potential. Diabetes. 2011;60:590–601.
  • Latella G, Vetuschi A, Sferra R, . Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice. Liver Int. 2009;29:997–1009.
  • Lan HY. Diverse roles of TGF-beta/Smads in renal fibrosis and inflammation. Int J Biol Sci. 2011;7:1056–1067.
  • Zhou TB, Qin YH, Zhou C, . Less expression of prohibitin is associated with the increased Caspase-3 expression and cell apoptosis in renal interstitial fibrosis rats. Nephrology (Carlton). 2012;17:189–196.
  • Zhou TB, Qin YH, Ou C, . All-trans retinoic acid can regulate the expressions of gelatinases and apolipoprotein E in glomerulosclerosis rats. Vascul Pharmacol. 2011;55:169–177.
  • Radford MG Jr, Donadio JV Jr, Bergstralh EJ, Grande JP. Predicting renal outcome in IgA nephropathy. J Am Soc Nephrol. 1997;8:199–207.
  • Zhou TB, Qin YH, Lei FY, Su LN, Zhao YJ, Huang WF. All-trans retinoic acid regulates the expression of apolipoprotein E in rats with glomerulosclerosis induced by Adriamycin. Exp Mol Pathol. 2011;90:287–294.
  • Zhou TB, Qin YH, Lei FY, Su LN, Zhao YJ, Huang WF. apoE expression in glomerulus and correlation with glomerulosclerosis induced by adriamycin in rats. Ren Fail. 2011; 33:348–354.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402–408.
  • Cury JL, Brunetto AF, Aydos RD. Negative effects of chronic kidney failure on lung function and functional capacity. Rev Bras Fisioter. 2010;14:91–98.
  • Piroozmand A, Hassan ZM. Evaluation of natural killer cell activity in pre and post treated breast cancer patients. J Cancer Res Ther. 2010;6:478–481.
  • Qin W, Chung AC, Huang XR, . TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. J Am Soc Nephrol. 2011;22:1462–1474.
  • Chung AC, Huang XR, Zhou L, Heuchel R, Lai KN, Lan HY. Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. Nephrol Dial Transplant. 2009;24:1443–1454.
  • Zhang D, Sun L, Xian W, . Low-dose paclitaxel ameliorates renal fibrosis in rat UUO model by inhibition of TGF-beta/Smad activity. Lab Invest. 2010;90:436–447.
  • Yu Z, Xing Y. All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-beta/Smad signaling. Biochem Biophys Res Commun. 2006;340:929–934.
  • Zhang H, Li N, Tang Y, Wu W, Zhang Q, Yu Z. Negative functional interaction of retinoic acid and TGF-beta signaling mediated by TG-interacting factor during chondrogenesis. Cell Physiol Biochem. 2009;23:157–164.
  • Zhong H, Wang HR, Yang S, . Targeting Smad4 links microRNA-146a to the TGF-beta pathway during retinoid acid induction in acute promyelocytic leukemia cell line. Int J Hematol. 2010;92:129–135.
  • Datta PK, Lianos EA. Retinoic acids inhibit inducible nitric oxide synthase expression in mesangial cells. Kidney Int. 1999;56:486–493.
  • Liu X, Lu L, Tao BB, Zhu YC. All-trans retinoic acid inhibits the increases in fibronectin and PAI-1 induced by TGF-beta1 and Ang II in rat mesangial cells. Acta Pharmacol Sin. 2008;29:1035–1041.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.