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Renal Failure Volume 35, 2013 - Issue 2
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Laboratory Study

Cloning and Expression of a Urate Oxidase and Creatinine Hydrolase Fusion Gene in Escherichia coli

Xin ChengDivision of Nephrology, The Second Xiangya Hospital, Research Institute of Nephrology, Central South University, Changsha, PR China;Department of Nephrology, Guangxi College of Traditional Chinese Medicine Affiliated Hospital, Nanning, PR China
,
Fang LiuDivision of Nephrology, The Second Xiangya Hospital, Research Institute of Nephrology, Central South University, Changsha, PR China;Health Management Center, Xiangya Hospital, Central South University, Changsha, PR China
,
Yanxin ZhangDivision of Nephrology, The Second Xiangya Hospital, Research Institute of Nephrology, Central South University, Changsha, PR China
&
Yunsheng JiangDivision of Nephrology, The Second Xiangya Hospital, Research Institute of Nephrology, Central South University, Changsha, PR China; Key Laboratory of Nephrology and Blood Purification in Hunan, Changsha, PR ChinaCorrespondence[email protected]
Pages 275-278 | Received 24 Sep 2012, Accepted 29 Oct 2012, Published online: 09 Jan 2013

REFERENCES

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  • Safra N, Ling GV, Schaible R, .Exclusion of urate oxidase as a candidate gene for hyperuricosuria in the Dalmatian dog using an interbreed backcross. J Hered. 2005;96(7):750–754.
  • Cheng X, Zhang Y-X, Yang B, .Construction of gene engineering bacterium to produce urate oxidase. Central South Pharmacy 2009;7(6):401–404.
  • Cheng X, Zhang Y-X, Zhou G-F. Production of creatinine hydrolase genetically engineered bacteria. J Biomed Eng Res. 2009;28(4):299–302.
  • Jain P, Shah S, Coussa R, . Potentials and limitations of microorganisms as renal failure biotherapeutics. Biologics. 2009;3:233–243.

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