Effect of Olestra on Faecal Water and Short-chain Fatty Acids

References

• Aggarwal A M, Camilleri M, Phillips S F, Schlagheck T G, Brown M L, Thomforde G M. Olestra, a nondigestible, nonabsorbable fat. Effects on gastrointestinal and colonic transit. Digestive Diseases and Sciences 1993; 38: 1009–1014
   PubMed Web of Science ®Google Scholar
• Augenlicht L H, Heerdt B G. Modulation of gene expression as a biomarker in colon. Journal of Cellular Biochemistry 1992; 16G(Suppl.)151–157
   Google Scholar
• Chernov A J, Doe W F, Gompertz D. Intra-jejunal volatile fatty acids in the stagnant loop syndrome. Gut 1972; 13: 103–106
   PubMed Web of Science ®Google Scholar
• Cummings J H. Short chain fatty acids in the human colon. Gut 1981; 22: 763–779
   PubMed Web of Science ®Google Scholar
• Cummings J H, Hill M J, Jenkins D JA, Pearson J R, Wiggins H S. Changes in faecal composition and colonic function due to cereal fibre. American Journal of Clinical Nutrition 1976; 29: 1468–1473
   PubMed Web of Science ®Google Scholar
• Cummings J H, Macfarlane G T. The control and consequences of bacterial fermentation in the human colon. Journal of Applied Bacteriology 1991; 70: 443–459
   PubMedGoogle Scholar
• Eastwood M A, Allgood G S. The effect of olestra on breath gas production and faecal microbial counts. European Journal of Clinical Nutrition 1995; 49: 627–639
   PubMed Web of Science ®Google Scholar
• Engelhardt W, Rechemmer G. Colonic transport of short-chain fatty acids and the importance of the microclimate. Intestinal Absorption and Secretion, E Skadhauge, K. Heintze. MTP Press Ltd, Lancaster 1984; 93–101, Boston; The Hague; Dordrecht
   Google Scholar
• Fallat R W, Glueck C J, Lutmer R, Mattson F H. Short-term study of sucrose polyester, a nonabsorbable fat-like material as a dietary agent for lowering plasma cholesterol. American Journal of Clinical Nutrition 1976; 29: 1204–1215
   PubMed Web of Science ®Google Scholar
• Fleming S E, Arce D S. Volatile fatty acids: Their production, absorption, utilization, and roles in human health. Clinics in Gastroenterology 1986; 15: 787–814
   PubMedGoogle Scholar
• Fleming S E, Choi S Y, Fitch M D. Absorption of short-chain fatty acids from the rat cecum. in vivo. Journal of Nutrition 1991; 121: 1787–1797
   PubMed Web of Science ®Google Scholar
• Fleming S E, Rodrigues M A. Influence of dietary fibre in fecal excretion of volatile fatty acids by human adults. Journal of Nutrition 1983; 113: 1613–1626
   PubMed Web of Science ®Google Scholar
• Friedel D, Levine G M. Effect of short-chain fatty acids on colonic function and structure. Journal of Parenteral and Enteral Nutrition 1992; 16: 1–4
   Web of Science ®Google Scholar
• Gamet L, Daviaud D, Denis-Pouxviel C, Remesy C, Murat J C. Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29. International Journal of Cancer, 52: 286–289
   Web of Science ®Google Scholar
• Gregory J, Foster K, Hazel T, Wiseman M. The dietary and nutritional survey of British adults. Office of Population Census and Surveys, Social Survey Division. Department of Health, HMSO, London 1990
   Google Scholar
• Holtug K, Clausen M R, Hovel H, Christiansen J, Mortensen P B. The colon in carbohydrate malabsorption: short-chain fatty acids, pH and osmotic diarrhoeas. Scandinavian Journal of Gastroenterology 1992; 27: 545–552
   PubMed Web of Science ®Google Scholar
• Høverstad T. Studies of short-chain fatty acid absorption in man. Scandinavian Journal of Gastroenterology 1986; 21: 257–260
   PubMed Web of Science ®Google Scholar
• Høverstad T. The normal microflora and short-chain fatty acids. The Regulatory and Protective Role of the Normal Microflora, R Grubb, T Midtvedt, E Norin. Macmillan, London 1989; 89–108
   Google Scholar
• Høverstad T, Bjørneklett A. Short chain fatty acids and bowel functions in man. Scandinavian Journal of Gastroenterology 1984; 19: 1059–1065
   PubMed Web of Science ®Google Scholar
• Høverstad T, Bjørneklett A, Fausa O, Midtvedt T. Short-chain fatty acids in the small-bowel bacterial overgrowth syndrome. Scandinavian Journal of Gastroenterology 1985; 20: 492–499
   PubMed Web of Science ®Google Scholar
• Høverstad T, Carlstedt-Duke B, Lingaas E, Midtvedt T, Norin K E, Saxerholt H, Steinbakk M. Influence of ampicillin, clindamycin and metronidazole on faecal excretion of short-chain fatty acids in healthy subjects. Scandinavian Journal of Gastroenterology 1986; 21: 621–626
   PubMed Web of Science ®Google Scholar
• Høverstad T, Carlstedt-Duke B, Lingaas E, Norin K E, Saxerholt H, Steinbakk M, Midtvedt T. Influence of oral intake of seven different antibiotics on faecal short chain fatty acids in healthy subjects. Scandinavian Journal of Gastroenterology 1986; 21: 997–1003
   PubMed Web of Science ®Google Scholar
• Høverstad T, Fausa O, Björneklett A, Böhmer T. Short-chain fatty acids in the normal human faeces. Scandinavian Journal of Gastroenterology 1984; 19: 375–381
   PubMed Web of Science ®Google Scholar
• Illmann R J, Toppling D L, Trimble R P. Effects of food restriction and starvation–refeeding on volatile fatty acid concentrations in the rat. Journal of Nutrition 1986; 116: 1694–1700
   Web of Science ®Google Scholar
• Leijonmarck C E, Carlstedt-Duke B, Gustafsson A, Midtvedt A C, Norin K E, Saxerholt H, Midtvedt T. Enteral nutrition and the function of the intestinal microflora in healthy adults. Clinical Nutrition 1990; 9: 163–167
   Web of Science ®Google Scholar
• Macfarlane G T, Cummings J H, Allison C. Protein degradation by human intestinal bacteria. Journal of General Microbiology 1986; 132: 1647–1656
   PubMedGoogle Scholar
• Maczulak A E, Wolin M J, Miller T L. Amounts of viable anaerobes, methanogens, and bacterial fermentation products in faeces of rats fed high-fiber or fiber-free diets. Applied and Environmental Microbiology 1993; 59: 657–662
   PubMed Web of Science ®Google Scholar
• Mattson F H, Nolen G A. Absorbability by rats of compounds containing from one to eight ester groups. Journal of Nutrition 1972; 102: 1171–1176
   PubMed Web of Science ®Google Scholar
• Mattson F H, Volpenhein R A. Rate and extent of absorption of the fatty acids of fully esterified glycerol, erythritol, xylitol, and sucrose as measured in thoracic duct canulated rats. Journal of Nutrition 1972; 102: 1177–1180
   PubMed Web of Science ®Google Scholar
• Midtvedt A C, Midtvedt T. Production of short chain fatty acids by the intestinal microflora during the first 2 years of human life. Journal of Pediatric Gastroenterology and Nutrition 1992; 15: 395–403
   Web of Science ®Google Scholar
• Midtvedt T. Influence of antibiotics on biochemical intestinal microflora-associated characteristics in man and animals. The Influence of Antibiotics on the Host–Parasite Relationship III, G Gillissen, W Opferkuch, G Peters, G Pulverer. Springer, Berlin 1989; 209–215, Heidelberg
   Google Scholar
• Miller K W, Allgood G S. Nutritional assessment of olestra, a noncaloric fat substitute. International Journal of Food Science 1993; 44((suppl. 1))S77–S82
   Google Scholar
• Mortensen P B, Holtug K, Rasmussen H S. Short-chain fatty acid production from mono-and disaccharides in a faecal incubation system: Implications for colonic fermentation of dietary fibre in humans. Journal of Nutrition 1988; 118: 321–325
   PubMed Web of Science ®Google Scholar
• Nuck B A, Schlagheck T G, Federle T W. Inability of the human fecal microflora to metabolize the nonabsorbable fat substitute, olestra. Journal of Industrial Microbiology 1994; 13: 328–334
   Google Scholar
• Rabassa A A, Rogers A I. The role of short-chain fatty acid metabolism in colonic disorders. American Journal of Gastroenterology 1992; 87: 419–423
   PubMed Web of Science ®Google Scholar
• Rasmussen H S, Holtug K, Andersen J R, Krag E, Mortensen P B. The influence of isphagula husk and lactulose on the in vivo and in vitro production capacity of short-chain fatty acids in humans. Scandinavian Journal of Gastroenterology 1987; 22: 406–410
   PubMed Web of Science ®Google Scholar
• Rasmussen H S, Holtug K, Mortensen P B. Degradation of amino acids to short-chain fatty acids in humans. Scandinavian Journal of Gastroenterology 1988; 23: 178–182
   PubMed Web of Science ®Google Scholar
• Rizzi G P, Taylor H M. A solvent-free synthesis of sucrose polyesters. Journal of American Oil Chemistry Society 1978; 55: 398–401
   Web of Science ®Google Scholar
• Roediger W EW. The starved colon–diminished mucosal nutrition, diminished absorption, and colitis. Diseases of Colon and Rectum 1990; 33: 858–862
   PubMed Web of Science ®Google Scholar
• Rolls B J, Pirraglia P A, Jones M B, Peters J C. Effects of olestra, a noncaloric fat substitute, on daily energy and fat intakes in lean men. American Journal of Clinical Nutrition 1992; 56: 84–92
   PubMed Web of Science ®Google Scholar
• Rombeau J L, Kripke S A. Metabolic and intestinal effects of short-chain fatty acids. Journal of Parenteral and Enteral Nutrition 1990; 14: 181S–185S
   PubMed Web of Science ®Google Scholar
• Ruchim M A. Volatile fatty acid production from amino acid degradation of human faecal suspensions. Gastroenterology 1984; 86: 1225
   Web of Science ®Google Scholar
• Ruppin H, Bar-Meier S, Soergel K H, Wood C M, Schmitt MG, Jr. Absorption of short-chain fatty acids by the colon. Gastroenterology 1980; 78: 1500–1507
   PubMed Web of Science ®Google Scholar
• Salyers A A, Leedle J Z. Carbohydrate metabolism in the human colon. Human Intestinal Microflora in Health and Disease, DJ Hentges. Academic Press, New York 1983; 147–165
   Google Scholar
• Scheppach W, Fabian C, Sachs M, Kasper H. The effect of starch malabsorption on fecal short chain fatty acid excretion in man. Scandinavian Journal of Gastroenterology 1988; 23: 755–759
   PubMed Web of Science ®Google Scholar
• Sellin J H. Methodological approaches to study colonic short chain fatty acid transport. Short Chain Fatty Acids: Falk symposium 73, HJ Binder, J Cummings, K. Soergel. Kluwer Academic Publishers, Doedrecht 1994; 71–82, Boston; London
   Google Scholar
• Siigur U, Tamm A, Tammur R. The faecal SCFAs and lactose tolerance in lactose malabsorbers. European Journal of Gastroenterology and Hepatology 1991; 3: 321–324
   Web of Science ®Google Scholar
• Siigur U, Ormisson A, Tamm A. Faecal short-chain fatty acids in breast-fed and bottle-fed infants. Acta Paediatrica 1993; 82: 536–538
   PubMed Web of Science ®Google Scholar
• Siigur U, Norin K E, Allgood G, Schlagheck T, Midtvedt T. Concentrations and correlations of faecal short-chain fatty acids and faecal water content in man. Microbial Ecology in Health and Disease 1994; 7: 287–294
   Web of Science ®Google Scholar
• Spiller G A, Chernoff M C, Hill R A, Gates J E, Nassar J J, Shipley E A. Effect of purified cellulose, pectin and a low-residue diet on faecal volatile fatty acids, transit time and faecal weight in humans. American Journal of Clinical Nutrition 1980; 33: 754–775
   PubMed Web of Science ®Google Scholar
• Titus E, Ahearn G A. Vertebrate gastrointestinal fermentation: transport mechanisms for volatile fatty acids. American Journal of Physiology 1992; 262: R547–R553
   Google Scholar
• Zijlstra J B, Beukema J, Wolthers B G, Byrne B M, Groen A, Donkert L. Pretreatment methods prior to gas chromatographic analysis of volatile fatty acids from faecal samples. Clinica Chimica Acta 1977; 78: 243–250
   PubMed Web of Science ®Google Scholar