The Increased Interleukin-13 in Patients with Systemic Lupus Erythematosus: Relations to Other Thl-, Th2-Related Cytokines and Clinical Findings

References

• Mosmann T. R., Coffman R. L. Thl and Th2 cells: Different patterns of lymphokine secretion lead to different function properties. Ann Rev Immunol 1989; 7: 145–173
   PubMed Web of Science ®Google Scholar
• Cher D. J., Mosmann T. R. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by T H 1 clones. J Immunol 1987; 138: 3688–3694
   PubMed Web of Science ®Google Scholar
• Kaufman D. L., ClareSalzler M., Tian J., Forsthuber T., Ting G. S., Robinson R., et al. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 1993; 366: 69–72
   PubMed Web of Science ®Google Scholar
• Merrill J. E., Kono D. H., Clayton J, Ando D. H., Hinto D. R., Hofman F. H. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and BIO. PL mice. Proc Natl Acad Sci USA 1992; 89: 574–578
   PubMed Web of Science ®Google Scholar
• Huang Y P, Perrin L H, Miescher P A. Correlation of T and B cell activities in vitro and IL-2 levels in systemic lupus erythematosus. J Immunol 1988; 141: 827–833
   PubMed Web of Science ®Google Scholar
• Linker-Israeli M., Deans R. J., Wallace D. J., Prehn J., Ozeri Chen T, Klinenberg J. R. Elevated levels of endogenous IL-6 in systemic lupus erythema tosus. J Immunol 1991; 147: 117–123
   PubMed Web of Science ®Google Scholar
• Horwitz D. A., Wang H., Gray J. D. Cytokine gene profile in circulating blood mononuclear cells from patients with systemic lupus erythematosus: increased interleukin-2 but interleukin-4 mRNA. Lupus 1994; 3: 423–428
   PubMed Web of Science ®Google Scholar
• Akahoshi M., Nakashima H., Tanaka Y., Kohsaka T., Nagano S., Ohgami E., et al. Thl/Th2 balance of peripheral T helper cells in systemic lupus erythemato sus. Arthritis Rheum 1999; 42: 1644–164
   PubMed Web of Science ®Google Scholar
• Ishida H., Muchamuel T., Sakaguchi S., Andrade S., Menon S., Howard M. Continuous administration of anti-inter-leukin-10 antibodies delays onset of autoimmunity in NZB/WF1 mice. JExpMed 1994; 179: 305–310
   Google Scholar
• Yoshii H., Yamamoto K., Okudaira H., Dohi M., Suko M., Fukata Y., et al. Age-related differential mRNA expression of T cell cytokine in NZB/NZW Fl mice. Lupus 1995; 4: 213–216
   PubMed Web of Science ®Google Scholar
• Horwitz D. A., Gray J. O., Behrendsen S. C., Kubin M., Rengaraju M., Ohtsuka K., et al. Decreased production of interleukin-12 and other Thl-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum 1998; 41: 838–844
   PubMed Web of Science ®Google Scholar
• Punnonen J., Aversa G., Cocks B. G., McKenzie A. N., Menon S., Zurawski G., et al. Interleukin 13 induces inter-leukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 1993; 90: 3730–3734
   PubMed Web of Science ®Google Scholar
• Houssiau F. A., Lefebvre C., Vanden Berghe M., Lambert M., Devogelaer J. P., Renauld J. C. Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity. Lupus 1995; 4: 393–395
   PubMed Web of Science ®Google Scholar
• Minty A., Chalon P., Derocq J. M., Dumont X., Guillemot J. C., Kaghad M., et al. Interleukin-13 is a new human lym-phokine regulating inflammatory and immune responses. Nature 1993; 362: 248–250
   PubMed Web of Science ®Google Scholar
• de Waal Malefyt R., Figdor C. G., Huijbens R., Mohan Peterson S., Bennett B., Culpepper J., et al. Effects of IL-13 on phenotype, cytokine production, and cyto toxic function of human monocyte. Comparison with IL-4 and modulation by IFN-γ or IL-10. J Immunol 1993; 151: 6370–6381
   PubMed Web of Science ®Google Scholar
• Tokano Y., Morimoto S., Hishikawa T., Murashima A., Abe M., Sekigawa I., et al. Subsets of activated T cells in patients with systemic lupus erythematosus: the relation to cell cycle. ScandJRheum 1997; 26: 37–42
   Google Scholar
• Morimoto S, Tokano Y, Takasaki Y, Hashimoto H. Relation between the level of soluble CD4, CD8 and CD23 molecules in sera and clinical manifestations and laboratory data in patients with systemic lupus erythematosus. Japan J Rheumatol 1996; 6: 301–307
   Google Scholar
• Tan E. M., Cohen A. S., Fries J. R., Masi A. T., McShane D. J., Rothfield N. F., et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271–1277
   PubMed Web of Science ®Google Scholar
• Bombardier C., Gladman D. D., Urowitz M. B., Caron D., Chang C. H. The com mittee on prognosis studies in SLE: Derivation of the SLEDAI. A disease activity index for lupus patients. Arthritis Rheum 1992; 35: 630–640
   PubMed Web of Science ®Google Scholar
• al-Janadi M., al-Balla S., al-Dalla A., Raziuddin S. Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases. J Clin Immunol 1993; 13: 58–63
   PubMed Web of Science ®Google Scholar
• Tanaka Y., Saito K., Shirakawa E., Ota T., Suzuki H., Eto S., et al. Production of B cell-stimulating factors by B cells in patients with systemic lupus erythematosus. J Immunol 1988; 141: 3043–3049
   PubMed Web of Science ®Google Scholar
• Llorente L., Richard Patin Y, Fior R., Alcocer Varela J., Wijdenes J., et al. In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjögren's syndrome, and systemic lupus erythematosus. A potential mechanism of B Lymphocyte hyperactivity and autoimmunity. Arthritis Rheum 1994; 37: 1647–1655
   PubMed Web of Science ®Google Scholar
• Takahashi S., Fossati L., Iwamoto M., Merino R., Motta R., Kobayakawa T., et al. Imbalance towards Thl predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. J Clin Invest 1996; 97: 1597–1604
   PubMed Web of Science ®Google Scholar
• Jeppson J. D., Patel H. R., Sakata N., Dormenco J., Terada N., Gelfand E. W. Requirement for dual singles by anti-CD40 and IL-4 for induction of nuclear factor-B, IL-6, and IgE in human lymphocytes. J Immunol 1998; 161: 1738–1742
   PubMed Web of Science ®Google Scholar
• Linker Israeli M., Honda M., Nand R., Mandyam R., Mengesha E., Wallace D. J., et al. Exogenous IL-10 and IL-4 down-regurate IL-6 production by SLE-derived PBMC. Clin Immunol 1999; 91: 6–16
   PubMed Web of Science ®Google Scholar
• Suzuki H., Kondig T. M., Furlonger C., Wakeham A., Timms E., Matsuyama T., et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science 1995; 268: 1472–1477
   PubMed Web of Science ®Google Scholar
• Shen C. R., Mazza G., Perry F. E., Beech J. T., Thompson S. J., Corato S., et al. T-helper 1 dominated responses to erythrocyte band 3 in NZB mice. Immunology 1996; 89: 195–199
   PubMed Web of Science ®Google Scholar
• Schuyler M., Gott K., Cheme A., Edwards B. Thl CD4+ cells adoptively transfer experimental hypersensitivity pneumonitis. Cellular Immunology 1997; 177: 169–175
   PubMed Web of Science ®Google Scholar