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LetterToEditor Article

Viral Infections and Resulting Inhibition of Xenobiotic Metabolizing Enzymes as the Possible Cause of Autoimmune Hepatitis in a Genetically Predisposed Person Persistently Exposed to Harmful Environmental Factor(s)

Pages 155-156 | Published online: 07 Jul 2009

References

  • Obermayer-Straub P, Strassburg C P, Manns M P. Autoimmune hepatitis. J Hepatol 2000; 32: 181–197
  • Czaja A J, Sievers C, Zein N N. Nature and behaviour of serum cytokines in type 1 autoimmune hepatitis. Dig Dis Sci 2000; 45: 1028–1035
  • Lee J D, Rhoades K, Economou J S. Interleukin-4 inhibits the expression of tumor necrosis factors alpha and beta, inter-leukin-1 beta and -6 and interferon gamma. Immunol Cell Biol 1995; 73: 57–61
  • Leeder J S, Kearns G L. Pharmacogenetics in pediatrics. Implications for practice. Ped Clin North Amer 1997; 44: 55–77
  • Renton K W. Hepatic drug metabolism and immunostimula-tion. Toxicology 2000; 142: 173–178
  • Abdel-Razzak Z, Corcos L, Fautrel A, Campion J P, Guil-Louzo A. Transforming growth factor-beta 1 down-regulates basal and polycyclic aromatic hydrocarbon-induced cytochromes P-450 1A1 and 1A2 in adult human hepatocytes in primary culture. Mol Pharmacol 1994; 46: 1100–1110
  • Chen J Q, Strom A, Gustafsson J A, Morgan E T. Suppression of the constitutive expression of cytochrome P-450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6. Mol Pharmacol 1995; 47: 940–947
  • Donato M T, Gomez-Lechon M J, Jover R, Nakamura T, Cas-Tell J V. Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isozymes in human hepatocytes in primary culture. J Pharmacol Exp Ther 1998; 284: 760–767
  • Dansette P M, Bonierbale E, Minoletti C, Beaune P H, Pessayre D, Mansuy D. Drug induced immunotoxicity. Eur J Drug Metab Pharmacokinet 1998; 23: 443–451

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