72
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Altered expression of the lymphocyte activation antigen CD30 in active celiac disease

, , , , , , , & show all
Pages 288-298 | Received 10 Jun 2009, Accepted 12 Oct 2009, Published online: 19 Feb 2010

References

  • Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, Schaadt M, Diehl V. Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells. Nature. 1982; 299:65–67.
  • Stein H, Mason DY, Gerdes J, O'Conner N, Wainscoat J, Pallsen G, Gatter K, Falini B, Delsol G, Lemke H. The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue. Evidence that Reed Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood. 1985; 66:848–858.
  • Chiarle R, Podda A, Prolla G, Gong J, Thorbecke GJ, Inghirami G. CD30 in normal and neoplastic cells. Clin Immunol. 1999; 90:157–164.
  • Durkop H, Latza U, Hummel M, Eitelbach F, Seed B, Stein H. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell. 1992; 68:421–427.
  • Smith CA, Gruss HJ, Davis T, Anderson D, Farrah T, Baker E, Sutherland GR, Brannan CI, Copeland NG, Jenkins NA, Grabstein KH, Gliniak B, McAlister IB, Fanslow W, Alderson M, Falk B, Gimpel S, Gillis S, Din WS, Goodwin RG, Armitage RJ. CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell. 1993; 73:1349–1360.
  • Smith CA, Farrah T, Goodwin RG. The TNF receptor superfamily of cellular and viral proteins: Activation, co-stimulation, and death. Cell. 1994; 76:959–962.
  • Tarkowski M, Chrul S, Bodalski J. The effect of IL-18 on IL-12-induced CD30 expression and IL-4 and IFN-g production by allergen and PPD specific T cells. Clin Exp Immunol. 2002; 127:78–84.
  • Munk ME, Kern P, Kaufmann SH. Human CD30+ cells are induced by Mycobacterium tuberculosis and present in tuberculosis lesions. Int Immunol. 1997; 9:713–720.
  • Alzona M, Jack HM, Fisher RI, Ellis TM. IL-12 activates IFN-y production through the preferential activation of CD30+T cells. J Immunol. 1995; 154:9–16.
  • Ellis TM, Simms PE, Slivnick DJ, Jack HM, Fisher RI. CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells. J Immunol. 1993; 151:2380–2389.
  • Nakamura T, Lee RK, Nam SY, Al-Ramadi BK, Koni PA, Bottomly KJ. Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma. J Immunol. 1997; 158:2090–2098.
  • Chilosi M, Facchetti F, Notarangelo LD, Romagnani S, Del Prete G, Almerigogna F, De Carli M, Pizzolo G. CD30 cell expression and abnormal soluble CD30 serum accumulation in Omenn's syndrome: Evidence for a T helper 2-mediated condition. Eur J Immunol. 1996; 26:329–334.
  • Piletta PA, Wirth S, Hommel L, Saurat JH, Hauser C. Circulating skin-homing T cells in atopic dermatitis. Selective upregulation of HLA-DR, interleukin-2R, and CD30 and decrease after combined UV-A and UV-B phototherapy. Arch Dermatol. 1996; 132:1230–1232.
  • Munk ME, Kern P, Kaufmann SH. Human CD30+ cells are induced by Mycobacterium tuberculosis and present in tuberculosis lesions. Int Immunol. 1997; 9:713–720.
  • Krams SM, Cao S, Hayashi M, Villanueva JC, Martinez OM. Elevations in IFN-gamma, IL-5, and IL-10 in patients with the autoimmune disease primary biliary cirrhosis: Association with autoantibodies and soluble CD30. Clin Immunol Immunopathol. 1996; 80:311–320.
  • Schieferdecker HL, Ullrich R, Hirseland H, Zeitz M. T cell differentiation antigens on lymphocytes in the human intestinal lamina propria. J Immunol. 1992; 149:2816–2822.
  • Eiras P, Roldan E, Camarero C, Olivares F, Bootello A, Roy G. Flow cytometry description of a novel CD3/CD7 intraepithelial lymphocyte subset in human duodenal biopsies: Potential diagnostic value in coeliac disease. Cytometry. 1998; 34:95–102.
  • Gerli R, Pitzalis C, Bistoni O, Falini B, Costantini V, Russano A, Lunardi C. CD30+T cells in rheumatoid synovitis: Mechanisms of recruitment and functional role. J Immunol. 2000; 164:4399–4407.
  • Trier JS. Celiac sprue. N Engl J Med. 1991; 325:1709.
  • van Heel DA, Hunt K, Greco L, Wijmenga C. Genetics in coeliac disease. Best Pract Res Clin Gastroenterol. 2005; 19:323–339.
  • Sollid LM. Intraepithelial lymphocytes in celiac disease: License to kill revealed. Immunity. 2004; 21:303–304.
  • Hansen HP, Kisselva T, Kobarg J, Horn-Lohrens O, Havsteen B, Lemke H. A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines. Int J Cancer. 1995; 63:750–756.
  • Horie R, Watanabe T. CD30: Expression and function in health and disease. Semin Immunol. 1998; 10:457–470.
  • Augustin MT, Kokkonen J, Karttunen R, Karttunen TJ. Serum granzymes and CD30 are increased in children's milk protein sensitive enteropathy and celiac disease. J Allergy Clin Immunol. 2005; 115:157–162.
  • Munk ME, Kern P, Kaufmann SH. Human CD30+ cells are induced by Mycobacterium tuberculosis and present in tuberculosis lesions. Int Immunol. 1997; 9:713–720.
  • Okumura M, Hidaka Y, Kuroda S, Takeoka K, Tada H, Amino N. Increased serum concentrations of soluble CD30 in patients with Graves' disease and Hashimoto's thyroiditis. J Clin Endocrinol Metab. 1997; 82:1757–1760.
  • Krams SM, Cao S, Hayashi M, Villanueva JC, Martinez OM. Elevations in IFN-γ, IL-5, and IL-10 in patients with the autoimmune disease primary biliary cirrhosis: Association with autoantibodies and soluble CD30. Clin Immunol Immunopathol. 1996; 80:311–320.
  • Gerli R, Muscat C, Bistoni O, Falini B, Tomassini C, Agea E, Tognellini R, Biagini P, Bertotto A. High levels of the soluble form of CD30 molecule in rheumatoid arthritis (RA) are expression of CD30+ T cell involvement in the inflamed joints. Clin Exp Immunol. 1995; 102:547–550.
  • Sancho D, Yáñez-Mó M, Tejedor R, Sánchez-Madrid F. Activation of peripheral blood T cells by interaction and migration through endothelium: Role of lymphocyte function antigen-1/intercellular adhesion molecule-1 and interleukin-15. Blood. 1999; 93:886–896.
  • Ebert EC. Interleukin 15 is a potent stimulant of intraepithelial lymphocytes. Gastroenterology. 1998; 115:1439–1445.
  • Ebert EC, Jabri B. Massive interleukin-12-induced interferon-γ production by interleukin-15-stimulated lamina propria lymphocytes followed by down-regulation of the interleukin-12 receptor. Immunology. 2008; 124:453–460.
  • León AJ, Garrote JA, Blanco-Quirós A, Calvo C, Fernández-Salazar L, Del Villar A, Barrera A, Arranz E. Interleukin 18 maintains a long-standing inflammation in coeliac disease patients. Clin Exp Immunol. 2006; 146:479–485.
  • Bernardo D, Garrote JA, Fernández-Salazar L, Riestra S, Arranz E. Is gliadin really safe for non-coeliac individuals? Production of interleukin 15 in biopsy culture from non-coeliac individuals challenged with gliadin peptides. Gut. 2007; 56:889–890.
  • Bernardo D, Garrote JA, Allegretti Y, León A, Gómez E, Bermejo-Martin JF, Calvo C, Riestra S, Fernández-Salazar L, Blanco-Quirós A, Chirdo F, Arranz E. Higher constitutive IL15R alpha expression and lower IL-15 response threshold in coeliac disease patients. Clin Exp Immunol. 2008; 154:64–73.
  • Maiuri L, Ciacci C, Auricchio S, Brown V, Quaratino S, Londei M. Interleukin 15 mediates epithelial changes in celiac disease. Gastroenterology. 2000; 119:996–1006.
  • Hüe S, Mention JJ, Monteiro RC, Zhang S, Cellier C. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity. 2004; 21:367–377.
  • Jabri B, de Serre NP, Cellier C, Evans K, Gache C, Carvalho C, Mougenot JF, Allez M, Jian R, Desreumaux P, Colombel JF, Matuchansky C, Cugnenc H, Lopez-Botet M, Vivier E, Moretta A, Roberts AI, Ebert EC, Guy-Grand D, Brousse N, Schmitz J, Cerf-Bensussan N. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease. Gastroenterology. 2000; 118:867–879.
  • Meresse B, Chen Z, Ciszewski C, Tretiakova M, Bhagat G, Krausz TN, Raulet DH, Lanier LL, Groh V, Spies T, Ebert EC, Green PH, Jabri B. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity. 2004; 21:357–366.
  • Di Sabatino A, Ciccocioppo R, Cupelli F, Cinque B, Millimaggi D, Clarkson MM. Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease. Gut. 2006; 55:469–477.
  • Mention JJ, Ben Ahmed M, Bègue B, Barbe U, Verkarre V, Asnafi V, Colombel JF, Cugnenc PH, Ruemmele FM, McIntyre E, Brousse N, Cellier C, Cerf-Bensussan N. Interleukin 15: A key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology. 2003; 125:730–745.
  • Tjon JM, Verbeek WH, Kooy-Winkelaar YM, Nguyen BH, van der Slik AR, Thompson A, Heemskerk MH, Schreurs MW, Dekking LH, Mulder CJ, van Bergen J, Koning F. Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor-CD3 expression in enteropathy-associated T-cell lymphoma. Blood. 2008; 112:5103–5110.
  • Murray A, Cuevas D, Jones DB, Wright DH. Study of the immunohistochemistry and T cell clonality of enteropathy-associated T cell lymphoma. Amer J Pathol. 1995; 146:509–519.
  • Farstad IN, Johansen FE, Vlatkovic L, Jahnsen J, Scott H, Fausa O, Bjørneklett A, Brandtzaeg P, Halstensen TS. Heterogeneity of intraepithelial lymphocytes in refractory sprue: Potential implications of CD30 expression. Gut. 2002; 51:372–378.
  • Gerli R, Lunardi C, Vinante F, Bistoni O, Pizzolo G, Pitzalis C. Role of CD30+T cells in rheumatoid arthritis: A counter regulatory paradigm for Th1-driven diseases. Trends Immunol. 2001; 22:72–77.
  • Marsh MM. Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity (celiac sprue). Gastroenterology. 1992; 102:330–354.
  • Cabanne A, Vázquez H, Argonz J, Moreno ML, Nachman F, Niveloni S, Mazure R, Kogan Z, Gómez JC, Mauriño E, Bai JC. Clinical utility of counting intraepithelial lymphocytes in celiac disease intestinal mucosa. Acta Gastroenterol Latinoam. 2007; 37:20–28.
  • Sugai E, Selvaggio G, Vazquez H, Viola M, Mazure R, Pizarro B, Smecuol E, Flores D, Pedreira S, Mauriño E, Gomez JC, Bai JC. Tissue transglutaminase in celiac disease: Assessment of a commercial kit. Am J Gastroenterol. 1997; 95:2318–2322.
  • Olerup O, Alder A, Fogdell A. HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in two hours. Tissue Antigens. 1993; 41:119–134.
  • Corazza GR, Biagi F, Volta U, Andreani ML, De Franceschi L, Gasbarrini G. Autoimmune enteropathy and villous atrophy in adults. Lancet. 1997; 350:359–360.
  • Madrigal L, Lynch S, Feighery C, Weir D, Kelleher D, O'Farrelly CJ. Flow cytometry analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies. Immunol Meth. 1993; 158:207–214.
  • Bulfone-Paus S, Dürkop H, Paus R, Krause H, Pohl T, Onu A. Differential regulation of human T lymphoblast functions by IL-2 and IL-15. Cytokine. 1997; 9:507–513.
  • Kilwinski J, Berger T, Mpalaskas J, Reuter S, Flick W, Kern P. Expression of CD30 mRNA, CD30L mRNA and a variant form of CD30 mRNA in restimulated peripheral blood mononuclear cells (PBMC) of patients with helminthic infections resembling a Th2 disease. Clin Exp Immunol. 1999; 115:114–119.
  • Thomas PD, Forbes A, Nicholls RJ, Ciclitira PJ. Altered expression of the lymphocyte activation markers CD30 and CD27 in patients with pouchitis. Scand J Gastroenterol. 2001; 36:258–264.
  • O'Keeffe J, Mills K, Jackson J, Feighery C. T cell proliferation, MHC class II restriction and cytokine products of gliadin stimulated peripheral blood mononuclear cells (PBMC). Clin Exp Immunol. 1999; 117:269–276.
  • Mizrachi A, Broide E, Buchs A, Kornberg A, Aharoni D, Bistritzer T, Rapoport MJ. Lack of correlation between disease activity and decreased stimulated secretion of IL-10 in lymphocytes from patients with celiac disease. Scand J Gastroenterol. 2002; 37:924–930.
  • Broide E, Scapa E, Bloch O, Shapiro M, Kimchi NA, Ben-Yehudah G, Rapoport MJ. Evidence for aberrant regulation of MAP kinase signal transduction pathway in peripheral blood mononuclear cells in patients with active celiac disease. Dig Dis Sci. 2009; 54:1270–1275.
  • Granzotto M, Dal Bo S, Quaglia S, Tommasini A, Piscianz E, Valencic E, Ferrara F, Martelossi S, Ventura A, Not T. Regulatory T-cell function is impaired in celiac disease. Dig Dis Sci. 2008; 54 7: 1513–1519.
  • Gerli R, Pitzalis C, Bistoni O, Falini B, Costantini V, Russano A, Lunardi C. CD30 T cells in rheumatoid synovitis: Mechanisms of recruitment and functional role. J Immunol. 2000; 164:4399–4407.
  • Gianfrani C, Levings MK, Sartirana C, Mazzarella G, Barba G, Zanzi D, Camarca A, Iaquinto G, Giardullo N, Auricchio S, Troncone R, Roncarolo MG. Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells. J Immunol. 2006; 177:4178–4186.
  • Benahmed M, Meresse B, Arnulf B, Barbe U, Mention JJ, Verkarre V, Allez M, Cellier C, Hermine O, Cerf-Bensussan N. Inhibition of TGF-beta signaling by IL-15: A new role for IL-15 in the loss of immune homeostasis in celiac disease. Gastroenterology. 2007; 132:994–1008.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.