Early human pregnancy serum cytokine levels predict autoimmunity in offspring

References

• Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a TH2 phenomenon?. Immunol Today. 1993 Jul; 14 7: 353–356.
   PubMedGoogle Scholar
• Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol. 2002 Dec; 2 12: 933–944.
   PubMed Web of Science ®Google Scholar
• Cote-Sierra J, Foucras G, Guo L, Chiodetti L, Young HA, Hu-Li J, Zhu J, Paul WE. Interleukin 2 plays a central role in Th2 differentiation. Proc Natl Acad Sci USA. 2004 Mar 16; 101 11: 3880–3885.
   Google Scholar
• Moore KW, O'Garra A, de Waal Malefyt R, Vieira P, Mosmann TR. Interleukin-10. Annu Rev Immunol. 1993; 11:165–190.
   PubMed Web of Science ®Google Scholar
• Chen WF, Zlotnik A. IL-10: A novel cytotoxic T cell differentiation factor. J Immunol. 1991 Jul 15; 147 2: 528–534.
   PubMed Web of Science ®Google Scholar
• Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature. 1996 Oct 31; 383 6603: 787–793.
   PubMed Web of Science ®Google Scholar
• Phillips TA, Ni J, Pan G, Ruben SM, Wei YF, Pace JL, Hunt JS. TRAIL (Apo-2L) and TRAIL receptors in human placentas: Implications for immune privilege. J Immunol. 1999 May 15; 162 10: 6053–6059.
   Google Scholar
• Marzi M, Vigano A, Trabattoni D, Villa ML, Salvaggio A, Clerici E, Clerici M. Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy. Clin Exp Immunol. 1996 Oct; 106 1: 127–133.
   Google Scholar
• Reinhard G, Noll A, Schlebusch H, Mallmann P, Ruecker AV. Shifts in the TH1/TH2 balance during human pregnancy correlate with apoptotic changes. Biochem Biophys Res Commun. 1998 Apr 28; 245 3: 933–938.
   PubMed Web of Science ®Google Scholar
• Matthiesen L, Ekerfelt C, Berg G, Ernerudh J. Increased numbers of circulating interferon-gamma- and interleukin-4-secreting cells during normal pregnancy. Am J Reprod Immunol. 1998 Jun; 39 6: 362–367.
   Google Scholar
• Tranchot-Diallo J, Gras G, Parnet-Mathieu F, Benveniste O, Marce D, Roques P, Milliez J, Chaouat G, Dormont D. Modulations of cytokine expression in pregnant women. Am J Reprod Immunol. 1997 Mar; 37 3: 215–226.
   Google Scholar
• Gargano JW, Holzman C, Senagore P, Thorsen P, Skogstrand K, Hougaard DM, Rahbar MH, Chung H. Mid-pregnancy circulating cytokine levels, histologic chorioamnionitis and spontaneous preterm birth. J Reprod Immunol. 2008 Oct; 79 1: 100–110.
   Web of Science ®Google Scholar
• Curry AE, Vogel I, Drews C, Schendel D, Skogstrand K, Flanders WD, Hougaard D, Olsen J, Thorsen P. Mid-pregnancy maternal plasma levels of interleukin 2, 6, and 12, tumor necrosis factor-alpha, interferon-gamma, and granulocyte–macrophage colony-stimulating factor and spontaneous preterm delivery. Acta Obstet Gynecol Scand. 2007; 86 9: 1103–1110.
   Web of Science ®Google Scholar
• Dealtry GB, O'Farrell MK, Fernandez N. The Th2 cytokine environment of the placenta. Int Arch Allergy Immunol. 2000 Oct; 123 2: 107–119.
   Google Scholar
• Meisser A, Chardonnens D, Campana A, Bischof P. Effects of tumour necrosis factor-alpha, interleukin-1 alpha, macrophage colony stimulating factor and transforming growth factor beta on trophoblastic matrix metalloproteinases. Mol Hum Reprod. 1999 Mar; 5 3: 252–260.
   PubMed Web of Science ®Google Scholar
• Sandberg-Bennich S, Dahlquist G, Kallen B. Coeliac disease is associated with intrauterine growth and neonatal infections. Acta Paediatr. 2002; 91 1: 30–33.
   Google Scholar
• Elfving M, Svensson J, Oikarinen S, Jonsson B, Olofsson P, Sundkvist G, Lindberg B, Lernmark A, Hyöty H, Ivarsson SA. Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age. Exp Diabetes Res. 2008; 2008:271958.
   PubMedGoogle Scholar
• Painter RC, Roseboom TJ, Bleker OP. Prenatal exposure to the Dutch famine and disease in later life: An overview. Reprod Toxicol. 2005 Sep–Oct; 20 3: 345–352.
   PubMed Web of Science ®Google Scholar
• Ashdown H, Dumont Y, Ng M, Poole S, Boksa P, Luheshi GN. The role of cytokines in mediating effects of prenatal infection on the fetus: Implications for schizophrenia. Mol Psych. 2006 Jan; 11 1: 47–55.
   PubMed Web of Science ®Google Scholar
• Trier JS. Celiac sprue. N Engl J Med. 1991 Dec 12; 325 24: 1709–1719.
   Google Scholar
• Dewar D, Pereira SP, Ciclitira PJ. The pathogenesis of coeliac disease. Int J Biochem Cell Biol. 2004 Jan; 36 1: 17–24.
   Google Scholar
• Sollid LM, Thorsby E. HLA susceptibility genes in celiac disease: Genetic mapping and role in pathogenesis. Gastroenterology. 1993; 105 3: 910–922.
   PubMed Web of Science ®Google Scholar
• Walker-Smith JA, Guandalini S, Schmitz J, Shmerling DH, Visakorpi JK. Revised criteria for diagnosis of coeliac disease: Report of working group of european society of paedriatic gastroeneterology and nutrition. Arch Dis Child. 1990; 65 909–911.
   Google Scholar
• Lernmark B, Elding-Larsson H, Hansson G, Lindberg B, Lynch K, Sjoblad S. Parent responses to participation in genetic screening for diabetes risk. Pediatr Diabetes. 2004 Dec; 5 4: 174–181.
   Google Scholar
• Björck S, Brundin C, Lörinc E, Lynch KF, Agardh D. Screening detects a high proportion of Celiac disease in young HLA-genotyped children. J Pediatr Gastroenterol Nutr. 2009; 49:1–6.
   Google Scholar
• Ryding J, French KM, Naucler P, Barnabas RV, Garnett GP, Dillner J. Seroepidemiology as basis for design of a human papillomavirus vaccination program. Vaccine. 2008 Sep 26; 26 41: 5263–5268.
   Google Scholar
• Mansouri R, Akbari F, Vodjgani M, Mahboudi F, Kalantar F, Mirahmadian M. Serum cytokines profiles in Iranian patients with preeclampsia. Iran J Immunol. 2007 Sep; 4 3: 179–185.
   PubMedGoogle Scholar
• Dong M, He J, Wang Z, Xie X, Wang H. Placental imbalance of Th1- and Th2-type cytokines in preeclampsia. Acta Obstet Gynecol Scand. 2005 Aug; 84 8: 788–793.
   PubMed Web of Science ®Google Scholar
• Ategbo JM, Grissa O, Yessoufou A, Hichami A, Dramane KL, Moutairou K, Miled A, Grissa A, Jerbi M, Tabka Z, Khan NA. Modulation of adipokines and cytokines in gestational diabetes and macrosomia. J Clin Endocrinol Metab. 2006 Oct; 91 10: 4137–4143.
   PubMed Web of Science ®Google Scholar
• Lynch KF, Lernmark B, Merlo J, Cilio CM, Ivarsson SA, Lernmark A. Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype. J Perinatol. 2008 Mar; 28 3: 211–217.
   Google Scholar
• Horuk R. The interleukin-8-receptor family: From chemokines to malaria. Immunol Today. 1994 Apr; 15 4: 169–174.
   Google Scholar
• Dinarello CA. Historical insights into cytokines. Eur J Immunol. 2007 Nov; 37 Suppl 1: S34–S45.
   PubMedGoogle Scholar
• Opsjłn SL, Wathen NC, Tingulstad S, Wiedswang G, Sundan A, Waage A, Austgulen R. Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol. 1993 Aug;1692 Pt 1: 397–404.
   Google Scholar
• Shimaoka Y, Hidaka Y, Tada H, Nakamura T, Mitsuda N, Morimoto Y, Murata Y, Amino N. Changes in cytokine production during and after normal pregnancy. Am J Reprod Immunol. 2000 Sep; 44 3: 143–147.
   Google Scholar
• Guidotti LG, Chisari FV. To kill or to cure: Options in host defense against viral infection. Curr Opin Immunol. 1996 Aug; 8 4: 478–483.
   Google Scholar
• Ramshaw IA, Ramsay AJ, Karupiah G, Rolph MS, Mahalingam S, Ruby JC. Cytokines and immunity to viral infections. Immunol Rev. 1997 Oct; 159:119–135.
   PubMed Web of Science ®Google Scholar
• Nolten WE, Goldstein D, Lindstrom M, McKenna MV, Carlson IH, Trump DL, Schiller J, Borden EC, Ehrlich EN. Effects of cytokines on the pituitary–adrenal axis in cancer patients. J Interferon Res. 1993 Oct; 13 5: 349–357.
   Google Scholar
• Seckl JR. Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms. Mol Cell Endocrinol. 2001 Dec 20; 185 1–2: 61–71.
   PubMedGoogle Scholar
• Gluckman PD, Cutfield W, Hofman P, Hanson MA. The fetal, neonatal, and infant environments—the long-term consequences for disease risk. Early Hum Dev. 2005 Jan; 81 1: 51–59.
   PubMed Web of Science ®Google Scholar
• Hamano N, Terada N, Maesako K, Hohki G, Ito T, Yamashita T, Konno A. Effect of female hormones on the production of IL-4 and IL-13 from peripheral blood mononuclear cells. Acta Otolaryngol Suppl. 1998; 537:27–31.
   Google Scholar
• Jara LJ, Lavalle C, Fraga A, Gomez-Sanchez C, Silveira LH, Martinez-Osuna P, Germain BF, Espinoza LR. Prolactin, immunoregulation, and autoimmune diseases. Semin Arthritis Rheum. 1991 Apr; 20 5: 273–284.
   PubMed Web of Science ®Google Scholar
• Pang ZJ, Zhou JG, Huang LP. Interleukin-10 may participate in regulating trophoblast invasion in human placentae throughout gestation. Am J Reprod Immunol. 2008 Jul; 60 1: 19–25.
   Google Scholar
• Santin AD, Hermonat PL, Ravaggi A, Bellone S, Pecorelli S, Roman JJ, Parham GP, Cannon MJ. Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8+ cytotoxic T lymphocytes. J Virol. 2000 May; 74 10: 4729–4737.
   Google Scholar
• Zaretsky MV, Alexander JM, Byrd W, Bawdon RE. Transfer of inflammatory cytokines across the placenta. Obstet Gynecol. 2004 Mar; 103 3: 546–550.
   PubMed Web of Science ®Google Scholar
• Aaltonen R, Heikkinen T, Hakala K, Laine K, Alanen A. Transfer of proinflammatory cytokines across term placenta. Obstet Gynecol. 2005 Oct; 106 4: 802–807.
   Web of Science ®Google Scholar
• Shimoya K, Matsuzaki N, Taniguchi T, Okada T, Saji F, Murata Y. Interleukin-8 level in maternal serum as a marker for screening of histological chorioamnionitis at term. Int J Gynaecol Obstet. 1997 May; 57 2: 153–159.
   Google Scholar
• Alaedini A, Green PH. Narrative review: Celiac disease: Understanding a complex autoimmune disorder. Ann Int Med. 2005 Feb 15; 142 4: 289–298.
   Google Scholar