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Research Article

Design considerations in building in silico equivalents of common experimental influenza virus assays

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Pages 282-293 | Published online: 19 Jan 2011

References

  • Carrat F, Vergu E, Ferguson NM, Lemaitre M, Cauchemez S, Leach S, Valleron AJ. Time lines of infection and disease in human influenza: A review of volunteer challenge studies. Am J Epidemiol. 2008; 167:775–785.
  • Baz M, Abed Y, Simon P, Hamelin M, Boivin G. Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses. J Infect Dis. 2010; 201:740–745.
  • Yen HL, Herlocher LM, Hoffmann E, Matrosovich MN, Monto AS, Webster RG, Govorkova EA. Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility. Antimicrob Agents Chemother. 2005; 49:4075–4084.
  • Matrosovich MN, Matrosovich T, Carr J, Roberts NA, Klenk HD. Overexpression of the α-2,6-Sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors. J Virol. 2003; 77:8418–8425.
  • Hatakeyama S, Sakai-Tagawa Y, Kiso M, Goto H, Kawakami C, Mitamura K, Sugaya N, Suzuki Y, Kawaoka Y. Enhanced expression of an α-2,6-linked sialic acid on MDCK cells improves isolation of human influenza viruses and evaluation of their sensitivity to a neuraminidase inhibitor. J Clin Microbiol. 2005; 43:4139–4146.
  • Tisdale M. Monitoring of viral susceptibility: New challenges with the development of influenza NA inhibitors. Rev Med Virol. 2000; 10:45–55.
  • Beauchemin C, McSharry J, Drusano G, Nguyen J, Went G, Ribeiro R, Perelson A. Modeling amantadine treatment of influenza A virus in vitro. J Theor Biol. 2008; 254:439–451.
  • Dahari H, Ribeiro R, Rice C, Perelson A. Mathematical modeling of subgenomic hepatitis C virus replication in Huh-7 cells. J Virol. 2007; 81:750–760.
  • Möhler L, Flockerzi D, Sann H, Reichl U. Mathematical model of influenza A virus production in large-scale microcarrier culture. Biotechnol Bioeng. 2005; 90:46–58.
  • Baccam P, Beauchemin C, Macken C, Hayden F, Perelson A. Kinetics of influenza A virus infection in humans. J Virol. 2006; 80:7590–7599.
  • Kermack W, McKendrick A. Contributions to the mathematical theory of epidemics, Part I. Proc R Soc Lond Ser A. 1927; 115:700–721.
  • Anderson R, May R. Population biology of infectious diseases: Part I. Nature. 1979; 280:361–367.
  • Anderson R, May R. Population biology of infectious diseases: Part II. Nature. 1979; 280:455–461.
  • Nowak M, May R, Anderson R. The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency disease. AIDS. 1990; 4:1095–1103.
  • Perelson A, Kirschner D, de Boer R. Dynamics of HIV infection of CD4+ T cells. Math Biosci. 1993; 114:81–125.
  • Nowak M, Bonhoeffer S, Hill A, Bohme R, Thomas H, McDade H. Viral dynamics in hepatitis B infection. Proc Natl Acad Sci USA. 1996; 93:4398–4404.
  • Hethcote H, Tudor D. Integral equation models for endemic infectious diseases. J Math Biol. 1980; 9:37–47.
  • Handel A, Longini I, Antia R. Neuraminidase inhibitor resistance in influenza: Assessing the danger of its generation and spread. PLoS Comput Biol. 2007; 3:2456–2464.
  • Handel A, Longini I, Antia R. Towards a quantitative understanding of the within-host dynamics of influenza A infections. J R Soc Interface. 2010; 7:35–47.
  • Dulbecco R, Vogt M. Plaque formation and isolation of pure lines with poliomyelitis viruses. J Exp Med. 1954; 99:167–182.
  • Hahon N, Booth J, Eckert H. Cell attachment and penetration by influenza virus. Infect Immun. 1973; 7:341–351.
  • Smith A, Adler F, Perelson A. An accurate two-phase approximate solution to an acute viral infection model. J Math Biol. 2010; 60:711–726.
  • Hale B, Knebel A, Botting C, Galloway C, Precious B, Jackson D, Elliott R, Randall R. CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215. Virology. 2009; 383:6–11.
  • Beauchemin C, Forrest S, Koster F. Modeling influenza viral dynamics in tissue. Lect Notes Comput Sci. 2006; 4163:23.
  • Holder BP, Simon P, Liao LE, Abed Y, Bouhy X, Beauchemin CAA, Boivin G. Assessing fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model 2010, Submitted.
  • Lloyd AL. Dependence of viral parameter estimates on the assumed viral life cycle: Limitations of studies of viral load data. Proc R Soc Lond B Biol Sci. 2001; 268:847–854.
  • Mittler JE, Sulzer B, Neumann AU, Perelson AS. Influence of delayed viral production on viral dynamics in HIV-1 infected patients. Math Biosci. 1998; 152:143–163.
  • Grossman Z, Feinberg M, Kuznetsov V, Dimitrov D, Paul W. HIV infection: How effective is drug combination treatment?. Immunol Today. 1998; 19:528–532.
  • Banks H, Bortz DM, Holte SE. Incorporation of variability into the modeling of viral delays in HIV infection dynamics. Math Biosci. 2003; 183:63–91.
  • Wearing HJ, Rohani P, Keeling MJ. Appropriate models for the management of infectious diseases. PLoS Med. 2005; 2:621–627.
  • Feng Z, Xu D, Zhao H. Epidemiological models with non-exponentially distributed disease stages and applications to disease control. Bull Math Biol. 2007; 69:1511–1536.
  • Beauchemin C. Probing the effects of the well-mixed assumption on viral infection dynamics. J Theor Biol. 2006; 242:464–477.
  • Monto A, McKimm-Breschkin J, Macken C, Hampson A, Hay A, Klimov A, Tashiro M, Webster R, Aymard M, Hayden F, Zambon M. Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use. Antimicrob Agents Chemother. 2006; 50:2395–2402.
  • Matrosovich M, Matrosovich T, Garten W, Klenk H. New low-viscosity overlay medium for viral plaque assays. Virol J. 2006; 3:63.
  • Beauchemin CA. MASyV: A Multi-Agent System Visualization package. Free open-source GNU GPL software available online on SourceForge.net 2007.

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