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Research Article

Model systems duplicating epidermolysis bullosa acquisita: A methodological review

Pages 102-110 | Received 26 Jun 2011, Accepted 12 Jul 2011, Published online: 19 Sep 2011

References

  • Chen M, Kim GH, Prakash L, Woodley DT. Epidermolysis bullosa acquisita: Autoimmunity to anchoring fibril collagen. Autoimmunity. 2012 Doi 10.3109/08916934.2011.606450.
  • Chiriac MT, Roesler J, Sindrilaru A, Scharffetter-Kochanek K, Zillikens D, Sitaru C. NADPH oxidase is required for neutrophil-dependent autoantibody-induced tissue damage. J Pathol. 2007; 212:56–65.
  • Sitaru C, Kromminga A, Hashimoto T, Brocker EB, Zillikens D. Autoantibodies to type VII collagen mediate Fcgamma-dependent neutrophil activation and induce dermal–epidermal separation in cryosections of human skin. Am J Pathol. 2002; 161:301–311.
  • Sitaru C, Mihai S, Otto C, Chiriac MT, Hausser I, Dotterweich B, Saito H, Rose C, Ishiko A, Zillikens D. Induction of dermal–epidermal separation in mice by passive transfer of antibodies specific to type VII collagen. J Clin Invest. 2005; 115:870–878.
  • Sesarman A, Mihai S, Chiriac MT, Olaru F, Sitaru AG, Thurman JM, Zillikens D, Sitaru C. Binding of avian IgY to type VII collagen does not activate complement and leuckocytes fail to induce subepidermal blistering in mice. Br J Dermatol. 2008; 158:463–471.
  • Yu X, Holdorf K, Kasper B, Zillikens D, Ludwig RJ, Petersen F. FcγRIIA and FcγRIIIB Are required for autoantibody-induced tissue damage in experimental human models of bullous pemphigoid. J Invest Dermatol. 2010; 30:2841–2844.
  • Kulkarni S, Sitaru C, Andersson KE, Damoulakis G, Davidson K, Hirose M, Juss J, Oxley D, Chessa TA, Ramadani F, Guillou H, Segonds-Pichon A, Fritsch A, Jarvis GE, Okkenhaug K, Ludwig R, Zillikens D, Mocsai A, Vanhaesebroeck B, Stephens LR, Hawkins PT. PI3Kβ plays a critical role in neutrophil activation by immune complexes. Sci Signal. 2011; 4 168: ra23.
  • Recke A, Sitaru C, Vidarsson G, Evensen M, Chiriac MT, Ludwig RJ, Zillikens D. Pathogenicity of IgG subclass autoantibodies to type VII collagen: Induction of dermal–epidermal separation. J Autoimmun. 2010; 34:435–444.
  • Yamamoto T, Kihara I, Morita T, Oite T. Attachment of polymorphonuclear leukocytes to glomeruli with immune deposits. J Immunol Methods. 1979; 26:315–323.
  • Gammon WR, Merritt CC, Lewis DM, Sams WMJ, Wheeler CEJ, Carlo J. Leukocyte chemotaxis to the dermal–epidermal junction of human skin mediated by pemphigoid antibody and complement: Mechanism of cell attachment in the in vitro leukocyte attachment method. J Invest Dermatol. 1981; 76:514–522.
  • Gammon WR, Inman AO3rd, Wheeler CEJr. Differences in complement-dependent chemotactic activity generated by bullous pemphigoid and epidermolysis bullosa acquisita immune complexes: Demonstration by leukocytic attachment and organ culture methods. J Invest Dermatol. 1984; 83:57–61.
  • Shimanovich I, Mihai S, Oostingh GJ, Ilenchuk TT, Bröcker EB, Opdenakker G, Zillikens D, Sitaru C. Granulocyte-derived elastase and gelatinase B are required for dermal–epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid. J Pathol. 2004; 204:519–527.
  • Liu Z, Zhao M, Li N, Diaz LA, Mayadas TN. Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood. 2006; 107:1063–1069.
  • Schön M, Ludwig RJ. Lymphocyte trafficking to inflames skin: Molecular mechanisms and implications for therapeutic target molecules. Expert Opin Ther Targets. 2005; 9:225–243.
  • Witebsky E. Concept of autoimmune disease. Ann N Y Acad Sci. 1966; 135:443–450.
  • Anhalt GJ, Labib RS, Voorhees JJ, Beals TF, Diaz LA. Induction of pemphigus in mice by passive transfer of IgG from patients with the disease. N Engl J Med.. 1993; 306:1189–1196.
  • Liu Z, Diaz LA, Troy JL, Taylor AF, Emery DJ, Fairley JA, Giudice GJ. A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180. J Clin Invest. 1993; 92:2480–2488.
  • Roscoe JT, Diaz LA, Sampaio SAP, Castro RM, Labib RS, Takahashi Y, Patel H, Anhalt GJ. Brazilian pemphigus foliaceus autoantibodies are pathogenic to BALB/C mice by passive transfer. J Invest Derm. 1985; 85:538–541.
  • Woodley DT, Chang C, Saadat P, Ram R, Liu Z, Chen M. Evidence that anti-type VII collagen antibodies are pathogenic and responsible for the clinical, histological, and immunological features of epidermolysis bullosa acquisita. J Invest Dermatol. 2005; 124:958–964.
  • Woodley DT, Ram R, Doostan A, Bandyopadhyay P, Huang Y, Remington J, Hou Y, Keene DR, Liu Z, Chen M. Induction of epidermolysis bullosa acquisita in mice by passive transfer of autoantibodies from patients. J Invest Dermatol. 2006; 126:1323–1330.
  • Chen M, Doostan A, Bandyopadhyay P, Remington J, Wang X, Hou Y, Liu Z. Woodley DT.The cartilage matrix protein subdomain of type VII collagen is pathogenic for epidermolysis bullosa acquisita. Am J Pathol. 2007; 170:2009–2018.
  • Sitaru C, Chiriac MT, Mihai S, Büning J, Gebert A, Ishiko A, Zillikens D. Induction of complement-fixing autoantibodies against type VII collagen results in subepidermal blistering in mice. J Immunol. 2006; 177:3461–3468.
  • Ludwig RJ, Recke A, Bieber K, Müller S, Marques Ade C, Banczyk D, Hirose M, Kasperkiewicz M, Ishii N, Schmidt E, Kasperkiewicz M, Ishii N, Schmidt E, Westermann J, Zillikens D, Ibrahim SM. Generation of antibodies of distinct subclasses and specificity is linked to H2s in an active mouse model of epidermolysis bullosa acquisita. J Invest Dermatol. 2011; 131:167–176.
  • Kasperkiewicz M, Hirose M, Recke A, Schmidt E, Zillikens D, Ludwig RJ. Clearance rates of circulating and tissue-bound autoantibodies to type VII collagen in experimental epidermolysis bullosa acquisita. Br J Dermatol. 2010; 162:1064–1070.
  • Borradori L, Caldwell JB, Briggaman RA, Burr CE, Gammon WR, James WD, Yancey KB. Passive transfer of autoantibodies from a patient with mutilating epidermolysis bullosa acquisita induces specific alterations in the skin of neonatal mice. Arch Dermatol. 1995; 131:590–595.
  • Shigemoto T, Nashiro K, Tsuchida T, Seki Y, Tamaki K. Administration of IgG fraction of epidermolysis bullosa acquisita (EBA) serum into mice. J Dermatol. 1988; 15:123–127.
  • Ludwig RJ, Zillikens D. Pathogenesis of epidermolysis bullosa acquisita. Dermatol Clin. 2011; 29:493–501.
  • Sitaru AG, Sesarman A, Mihai S, Chiriac MT, Zillikens D, Hultman P, Solbach W, Sitaru C. T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita. J Immunol. 2010; 184:1596–1603.
  • Gross TL, Ihrke PJ, Walder EJ. 2005. Skin diseases of the dog and cat: Clinical and histopathologic diagnosisBlackwell Pub Professional.
  • Olivry T, Fine JOD, Dunston SM, Chasse D, Tenorio AP, Monteiro-Riviere NA, Chen M, Woodley DT. Canine epidermolysis bullosa acquisita: Circulating autoantibodies target the aminoterminal non-collagenous (NC1) domain of collagen VII in anchoring fibrils. Vet Dermatol. 1998; 9:19–31.
  • Olivry T, Jackson HA. Diagnosing new autoimmune blistering skin diseases of dogs and cats. Clin Tech Small Anim Pract. 2001; 16:225–229.
  • Olivry T, Petersen A, Dunston SM, Chen M. Novel localised variant of canine epidermolysis bullosa acquisita. Vet Rec. 2000; 146:193–194.
  • Kuriya B, Arkema EV, Bykerk VP, Keystone EC. Efficacy of initial methotrexate monotherapy versus combination therapy with a biological agent in early rheumatoid arthritis: A meta-analysis of clinical and radiographic remission. Ann Rheum Dis. 2010; 69:1298–1304.
  • Scho¨n MP, Boehncke WH. Psoriasis. N Engl J Med. 2005; 352:1899–1912.
  • Ludwig RJ, Schmidt E. Cytokines in autoimmune bullous skin diseases. Epiphenomena or contribution to pathogenesis?. G Ital Dermatol Venereol. 2009; 144:339–349.

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