Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients

References

• Li, G. C., and Z. Werb. 1982. Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts. Proc. Natl. Acad. Sci. USA. 79: 3218–3222
   PubMed Web of Science ®Google Scholar
• Riabowol, K. T., L. A. Mizzen, and W. J. Welch. 1988. Heat shock is lethal to fibroblasts microinjected with antibodies against hsp70. Science 242: 433–436
   PubMed Web of Science ®Google Scholar
• Lindquist, S., and E. A. Craig. 1988. The heat-shock proteins. Annu. Rev. Genet. 22: 631–677
   PubMed Web of Science ®Google Scholar
• Welch, W. J. 1993. Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells. Philos. Trans. R. Soc. Lond. B Biol. Sci. 339: 327–333
   PubMed Web of Science ®Google Scholar
• Jaattela, M. 1999. Heat shock proteins as cellular lifeguards. Ann. Med. 31: 261–271
   PubMed Web of Science ®Google Scholar
• Hunt, C., and R. I. Morimoto. 1985. Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. Proc. Natl. Acad. Sci. USA. 82: 6455–6459
   PubMed Web of Science ®Google Scholar
• Tavaria, M., T. Gabriele, I. Kola, and R. L. Anderson. 1996. A hitchhiker's guide to the human Hsp70 family. Cell Stress Chaperones 1: 23–28
   PubMed Web of Science ®Google Scholar
• Daugaard, M., M. Rohde, and M. Jaattela. 2007. The heat shock protein 70 family: highly homologous proteins with overlapping and distinct functions. FEBS Lett. 581: 3702–3710
   PubMed Web of Science ®Google Scholar
• Li, Y., J. Subjeck, G. Yang, et al. 2006. Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy. Vaccine 24: 5360–5370
   PubMed Web of Science ®Google Scholar
• Gong, J., Y. Zhang, J. Durfee, et al. 2010. A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use. J. Immunol. 184: 488–496
   PubMed Web of Science ®Google Scholar
• Aquino, D. A., E. Capello, J. Weisstein, et al. 1997. Multiple sclerosis: altered expression of 70- and 27-kDa heat shock proteins in lesions and myelin. J. Neuropathol. Exp. Neurol. 56: 664–672
   PubMed Web of Science ®Google Scholar
• Chabas, D., S. E. Baranzini, D. Mitchell, et al. 2001. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 294: 1731–1735
   PubMed Web of Science ®Google Scholar
• Cwiklinska, H., M. P. Mycko, O. Luvsannorov, et al. 2003. Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains. Int. Immunol. 15: 241–249
   PubMedGoogle Scholar
• Mycko, M. P., H. Cwiklinska, J. Szymanski, et al. 2004. Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II. J. Immunol. 172: 202–213
   PubMedGoogle Scholar
• Lund, B. T., Y. Chakryan, N. Ashikian, et al. 2006. Association of MBP peptides with Hsp70 in normal appearing human white matter. J. Neurol. Sci. 249: 122–134
   PubMedGoogle Scholar
• Bomprezzi, R., M. Ringner, S. Kim, et al. 2003. Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease. Hum. Mol. Genet. 12: 2191–2199
   PubMed Web of Science ®Google Scholar
• Mandel, M., M. Gurevich, R. Pauzner, et al. 2004. Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus. Clin. Exp. Immunol. 138: 164–170
   PubMed Web of Science ®Google Scholar
• Satoh, J., M. Nakanishi, F. Koike, et al. 2005. Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Neurobiol. Dis. 18: 537–550
   PubMed Web of Science ®Google Scholar
• Comabella, M., and R. Martin. 2007. Genomics in multiple sclerosis – current state and future directions. J. Neuroimmunol. 187: 1–8
   PubMed Web of Science ®Google Scholar
• Cwiklinska, H., M. P. Mycko, B. Szymanska, et al. 2010. Aberrant stress-induced Hsp70 expression in immune cells in multiple sclerosis. J. Neurosci. Res. 88: 3102–3110
   PubMedGoogle Scholar
• Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402–408
   PubMed Web of Science ®Google Scholar
• Welch, W. J., and J. R. Feramisco. 1984. Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J. Biol. Chem. 259: 4501–4513
   PubMed Web of Science ®Google Scholar
• Flynn, G. C., T. G. Chappell, and J. E. Rothman. 1989. Peptide binding and release by proteins implicated as catalysts of protein assembly. Science 245: 385–390
   PubMed Web of Science ®Google Scholar
• Beckmann, R. P., L. E. Mizzen, and W. J. Welch. 1990. Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly. Science 248: 850–854
   PubMed Web of Science ®Google Scholar
• Hartl, F. U., and M. Hayer-Hartl. 2002. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295: 1852–1858
   PubMed Web of Science ®Google Scholar
• Mosser, D. D., and R. I. Morimoto. 2004. Molecular chaperones and the stress of oncogenesis. Oncogene 23: 2907–2918
   PubMed Web of Science ®Google Scholar
• Benn, S. C., and C. J. Woolf. 2004. Adult neuron survival strategies – slamming on the brakes. Nat. Rev. Neurosci. 5: 686–700
   PubMed Web of Science ®Google Scholar
• Beere, H. M. 2004. “The stress of dying": the role of heat shock proteins in the regulation of apoptosis. J. Cell Sci. 117: 2641–2651
   PubMed Web of Science ®Google Scholar
• Lanneau, D., A. de Thonel, S. Maurel, et al. 2007. Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27. Prion 1: 53–60
   PubMed Web of Science ®Google Scholar
• Dyment, D. A., G. C. Ebers, and A. D. Sadovnick. 2004. Genetics of multiple sclerosis. Lancet Neurol. 3: 104–110
   PubMed Web of Science ®Google Scholar
• Aquino, D. A., A. A. Klipfel, C. F. Brosnan, and W. T. Norton. 1993. The 70-kDa heat shock cognate protein (HSC70) is a major constituent of the central nervous system and is up-regulated only at the mRNA level in acute experimental autoimmune encephalomyelitis. J. Neurochem. 61: 1340–1348
   PubMedGoogle Scholar
• Bajramovic, J. J., M. Bsibsi, S. B. Geutskens, et al. 2000. Differential expression of stress proteins in human adult astrocytes in response to cytokines. J. Neuroimmunol. 106: 14–22
   PubMed Web of Science ®Google Scholar
• Mansilla, M. J., X. Montalban, and C. Espejo. 2012. Heat shock protein 70: roles in multiple sclerosis. Mol. Med 18: 1018--1028
   Google Scholar
• Tytell, M., and P. L. Hooper. 2001. Heat shock proteins: new keys to the development of cytoprotective therapies. Expert Opin. Ther. Target. 5: 267–287
   PubMedGoogle Scholar
• Turturici, G., G. Sconzo, and F. Geraci. 2011. Hsp70 and its molecular role in nervous system diseases. Biochem. Res. Int. 2011: 618127
   PubMedGoogle Scholar
• Sospedra, M., and R. Martin. 2005. Immunology of multiple sclerosis. Annu. Rev. Immunol. 23: 683–747
   PubMed Web of Science ®Google Scholar
• Noseworthy, J. H., C. Lucchinetti, M. Rodriguez, and B. G. Weinshenker. 2000. Multiple sclerosis. N. Engl. J. Med. 343: 938–952
   PubMed Web of Science ®Google Scholar
• Van Eden, W., G. Wick, S. Albani, and I. Cohen. 2007. Stress, heat shock proteins, and autoimmunity: how immune responses to heat shock proteins are to be used for the control of chronic inflammatory diseases. Ann. N. Y. Acad. Sci. 1113: 217–237
   PubMed Web of Science ®Google Scholar
• Edelman, D. A., Y. Jiang, J. G. Tyburski, et al. 2007. Lipopolysaccharide up-regulates heat shock protein expression in rat lung pericytes. J. Surg. Res. 140: 171–176
   PubMed Web of Science ®Google Scholar
• Bernardini, C., A. Zannoni, M. L. Bacci, and M. Forni. 2010. Protective effect of carbon monoxide pre-conditioning on LPS-induced endothelial cell stress. Cell Stress Chaperones 15: 219–224
   PubMedGoogle Scholar
• Bustamante, M. F., N. Fissolo, J. Rio, et al. 2011. Implication of the Toll-like receptor 4 pathway in the response to interferon-beta in multiple sclerosis. Ann. Neurol. 70: 634–645
   PubMed Web of Science ®Google Scholar
• Mycko, M. P., H. Cwiklinska, A. Walczak, et al. 2008. A heat shock protein gene (Hsp70.1) is critically involved in the generation of the immune response to myelin antigen. Eur. J. Immunol. 38: 1999–2013
   PubMed Web of Science ®Google Scholar