Autoantibody response and pregnancy-related pathology induced by combined LPS and tetanus toxoid hyperimmunization in BALB/c and C57BL/6 mice

References

• Shoenfeld, Y., B. Gilburd, M. Abu-Shakra, et al. 2008. The mosaic of autoimmunity: genetic factors involved in autoimmune diseases – 2008. Isr. Med. Assoc. J. 10: 3–7
   PubMedGoogle Scholar
• Shoenfeld, Y., G. Zandman-Goddard, L. Stojanovich, et al. 2008. The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases – 2008. Isr. Med. Assoc. J. 10: 8–12
   PubMed Web of Science ®Google Scholar
• Kivity, S., N. Agmon-Levin, M. Blank, and Y. Shoenfeld. 2009. Infections and autoimmunity – friends or foes? Trends Immunol. 30: 419–414
   Google Scholar
• Perricone, C., N. Agmon-Levin, S. Colafrancesco, and Y. Shoenfeld. 2013. Vitamins and systemic lupus erythematosus: to D or not to D. Expert. Rev. Clin. Immunol. 9: 397–399
   PubMed Web of Science ®Google Scholar
• Kamen, D. L., and C. Aranow. 2008. The link between vitamin D deficiency and systemic lupus erythematosus. Curr. Rheumatol. Rep. 10: 273–280
   Google Scholar
• Molina, V., and Y. Shoenfeld. 2005. Infection, vaccines and other environmental triggers of autoimmunity. Autoimmunity. 38: 235–245
   PubMed Web of Science ®Google Scholar
• Delogu, L. G., S. Deidda, G. Delitala, and R. Manetti. 2011. Infectious diseases and autoimmunity. J. Infect. Dev. Countries. 5: 679–687
   PubMed Web of Science ®Google Scholar
• Bogdanos, D. P., D. S. Smyk, P. Invernizzi, et al. 2012. Infectome: a platform to trace infectious triggers of autoimmunity. Autoimmun. Rev. 12: 726–740
   PubMedGoogle Scholar
• Murali-Krishna, K., J. D. Altman, M. Suresh, et al. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity. 8: 177–187
   PubMed Web of Science ®Google Scholar
• Miller, S. D., C. L. Vanderlugt, W. S. Begolka, et al. 1997. Persistent infection with Thailer’s virus leads to CNS autoimmunity via epitope spreading. Nat. Med. 3: 1133–1136
   PubMed Web of Science ®Google Scholar
• Benoist, C., and D. Mathis. 2001. Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? Nat. Immunol. 2: 797–801
   Web of Science ®Google Scholar
• Wucherpfennig, K. W. 2001. Mechanisms for the induction of autoimmunity by infectious agents. J. Clin. Invest. 108: 1097–1104
   PubMed Web of Science ®Google Scholar
• Levy, Y., O. Almog, A. Gorsgtein, and Y. Shoenfeld. 2006. The environment and antiphospholipid syndrome. Lupus. 15: 784–790
   PubMedGoogle Scholar
• Agmon-Levin, N., C. Rosario, B.-S. Porat-Katz, et al. 2013. Ferritin in the antiphospholipid syndrome and its catastrophic variant (cAPS). Lupus. 22: 1327–1335
   PubMed Web of Science ®Google Scholar
• Meroni, P. L., N. di Simone, C. Testoni, et al. 2004. Antiphospholipid antibodies as cause of pregnancy loss. Lupus. 13: 649–652
   PubMed Web of Science ®Google Scholar
• Willems, G. M., M. P. Janssen, M. M. Pelsers, et al. 1996. Role of divalency in the high-affinity binding of anticardiolipin antibody-β2 glycoprotein I complexes to lipid membranes. Biochemistry. 35: 13833–13842
   PubMed Web of Science ®Google Scholar
• Franklin, R. D., N. Hollier, and W. H. Kitteh. 2000. β2-Glycoprotein 1 as a marker of antiphospholipid syndrome in women with recurrent pregnancy loss. Fertil. Steril. 73: 531–535
   PubMedGoogle Scholar
• Matsuura, E., J. Inagaki, H. Kasahara, et al. 2000. Proteolytic cleavage of beta(2)-glycoprotein I: reduction of antigenicity and the structural relationship. Int. Immunol. 12: 1183–1192
   PubMed Web of Science ®Google Scholar
• Rojkjaer, R., D. A. Klaerke, and I. Schousboe. 1997. Characterization of the interaction between beta2-glycoprotein I and calmodulin, and identification of a binding sequence in beta2-glycoprotein I. Biochim. Biophys. Acta. 1339: 217–225
   PubMedGoogle Scholar
• Chonn, A., S. C. Semple, and P. R. Cullis. 1995. Beta 2 glycoprotein I is a major protein associated with very paridly cleared liposomes in vivo, suggesting a significant role in the immune clearance of “non-self” particles. J. Biol. Chem. 270: 25845–25849
   PubMed Web of Science ®Google Scholar
• Balasubramanian, K., J. Chandra, and A. J. Schroit. 1997. Immune clearance of phosphatidylserine-expressing cells by phagocytes. The role of beta2-glycoprotein I in macrophage recognition. J. Biol. Chem. 272: 31113–31117
   PubMed Web of Science ®Google Scholar
• Nimph, J. H., H. Wurm, and G. M. Kostner. 1987. β2-glycoprotein 1 (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation. Atherosclerosis. 63: 109–114
   PubMedGoogle Scholar
• Schwarzenbacher, R., K. Zeth, K. Diederichs, et al. 1999. Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome. EMBO J. 18: 6228–6239
   PubMed Web of Science ®Google Scholar
• Iverson, G. M., E. Matsuura, E. J. Victoria, et al. 2002. The orientation of β2GPI on the plate is important for the binding of anti-β2GPI autoantibodies by ELISA. J. Autoimmun. 18: 289–297
   PubMedGoogle Scholar
• de Laat, B., R. H. Derksen, M. van Lummel, et al. 2006. Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change. Blood. 107: 1916–1924
   PubMed Web of Science ®Google Scholar
• Bouma, B., P. G. de Groot, J. M. van den Elsen, et al. 1999. Adhesion mechanism of human β2-glycoprotein I to phospholipids based on its crystal structure. EMBO J. 18: 5166–5174
   PubMed Web of Science ®Google Scholar
• Agar, C., G. M. van Os, M. Morgelin, et al. 2010. Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood. 116: 1336–1343
   PubMed Web of Science ®Google Scholar
• Agar, C., P. G. de Groot, M. Mörgelin, et al. 2011. β2-Glycoprotein I: a novel component of innate immunity. Blood. 117: 6939–6947
   PubMed Web of Science ®Google Scholar
• Harel, M., A. Aron-Maor, Y. Sherer, et al. 2005. The infectious etiology of the antiphospholipid syndrome: links between infection and autoimmunity. Immunobiology. 210: 743–747
   PubMedGoogle Scholar
• Stojanović, M., I. Živković, A. Inić-Kanada, et al. 2009. The context of tetanus toxoid application influences the outcome of antigen-specific and self-directed humoral immune response. Microbiol. Immunol. 53: 89–100
   PubMedGoogle Scholar
• Zivkovic, I., M. Stojanovic, V. Petrusic, et al. 2011. Induction of APS after TTd hyper-immunization has a different outcome in BALB/c and C57BL/6 mice. Am. J. Reprod. Immunol. 65: 492–502
   PubMed Web of Science ®Google Scholar
• Zivkovic, I., V. Petrusic, M. Stojanovic, et al. 2012. Induction of decreased fecundity by tetanus toxoid hyper-immunization in C57BL/6 mice depends on the applied adjuvant. Innate Immun. 18: 333–342
   PubMed Web of Science ®Google Scholar
• Dimitrijević, L., I. Živković, M. Stojanović, et al. 2012. Vaccine model of antiphospholipid syndrome induced by tetanus vaccine. Lupus. 21: 195–202
   PubMedGoogle Scholar
• Petrušić, V., I. Živković, M. Stojanović, et al. 2011. Antigenic specificity and expression of a natural idiotope on human pentameric and hexameric IgM polymers. Immunol. Res. 51: 97–107
   PubMedGoogle Scholar
• Zivkovic, I. P., M. M. Stojanovic, V. Z. Petrusic, et al. 2010. Network connectivity is shown to change in C57BL/6 mice during a continuing immune response subsequent to tetanus toxoid hyperimmunization. Biol. Res. 43: 393–402
   PubMedGoogle Scholar
• Dimitrijević, L., M. Radulović, B. Ćirić, et al. 1992. Immunochemical characterisation of a murine monoclonal anti-idiotypic antibody. J. Immunoassay. 13: 181–196
   PubMedGoogle Scholar
• Radulovic, M., B. Ciric, A. Jurisic, et al. 1997. Expression of Y7 idiotope on IgM molecules from cord sera. In Immune Regulation in Health and Disease, 1st ed. M. Lukic, M. Mostarica-Stojkovic, K. Cuperlovic and M. Colic, eds. Academic Press, London, UK. p. 205–211
   Google Scholar
• Ivanović, V., L. Popović, K. Kovacina, et al. 1990. Detection of cross-reacting idiotypes in sera of lymphoma patients by inverse monoclonal radioimmunoassay. Acta Haematol. 84: 64–67
   PubMedGoogle Scholar
• Dimitrijević, L. A., M. I. Radulović, B. P. Ćirić, et al. 1999. Human monoclonal IgM DJ binds to ssDNA and human commensal bacteria. Hum. Antibodies. 9: 37–45
   PubMedGoogle Scholar
• Meroni, P. L., M. O. Borghi, E. Raschi, and F. Tedesco. 2011. Pathogenesis of antiphospholipid syndrome: understanding the antibodies. Nat. Rev. Rheumatol. 7: 330–339
   PubMed Web of Science ®Google Scholar
• Soler-Rodriguez, A. M., H. Zhang, H. S. Lichenstein, et al. 2000. Neutrophil activation by bacterial lipoprotein versus lipopolysaccharide: differential requirements for serum and CD14. J. Immunol. 164: 2674–2683
   PubMedGoogle Scholar
• Pelletier, M., L. Maggi, A. Micheletti, et al. 2010. Evidence for a cross-talk between human neutrophils and Th17 cells. Blood. 115: 335–343
   PubMed Web of Science ®Google Scholar
• Mills, C. D., K. Kincaid, J. M. Alt, et al. 2000. M-1/M-2 macrophages and the Th1/Th2 paradigm. J. Immunol. 164: 6166–6173
   PubMed Web of Science ®Google Scholar
• Raschi, E., C. B. Chighizola, C. Grossi, et al. 2014. β2-glycoprotein I, lipopolysaccharide and endothelial TLR4: three players in the two hit theory for anti-phospholipid-mediated thrombosis. J. Autoimmun. doi:10.1016/j.jaut.2014.03.001. [Epub ahead of print]
   Google Scholar
• Carrera-Silva, E. A., R. C. Cano, N. Guinazu, et al. 2008. TLR2, TLR4 and TLR9 are differentially modulated in liver lethally injured from BALB/c and C57BL/6 mice during Trypanosoma cruzi acute infection. Mol. Immunol. 45: 3580–3588
   PubMedGoogle Scholar
• Liu, T., T. Matsuguchi, N. Tsuboi, et al. 2002. Differences in expression of Toll-like receptors and their reactivities in dendritic cells in BALB/c and C57BL/6 mice. Infect. Immun. 70: 6638–6645
   PubMed Web of Science ®Google Scholar
• Robertson, S. A., C. T. Roberts, E. van Beijering, et al. 2004. Effect of beta2-glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice. Mol. Hum. Reprod. 10: 409–416
   PubMedGoogle Scholar
• McIntyre, J. A. 2003. Antiphospholipid antibodies (aPL) in implantation failures. Am. J. Reprod. Immunol. 49: 221–229
   PubMedGoogle Scholar
• Agostinis, C., P. Durigutto, D. Sblattero, et al. 2014. A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome. Blood. 123: 3478–3487
   PubMed Web of Science ®Google Scholar
• Agostinis, C., S. Biffi, C. Garrovo, et al. 2011. In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions. Blood. 118: 4231–4238
   PubMed Web of Science ®Google Scholar
• Petrušić, V., I. Živković, L. Muhandes, et al. 2014. Infection-induced autoantibodies and pregnancy related pathology: an animal model. Reprod. Fertil. Dev. 26: 578–586
   PubMedGoogle Scholar
• de la Torre, Y. M., F. Pregnolato, F. D’Amelio, et al. 2012. Anti-phospholipid induced murine fetal loss: novel protective effect of a peptide targeting the β2glycoprotein I phospholipidbinding site. Implications for human fetal loss. J. Autoimmun. 38: J209–J215
   PubMed Web of Science ®Google Scholar
• Coutinho, A. 1989. Beyond clonal selection and network. Immunol. Rev. 110: 63–87
   PubMed Web of Science ®Google Scholar
• Avrameas, S., T. Ternynck, T. Tsonis, and P. Lymberi. 2007. Naturally occuring B-cell autoreactivity: a critical overview. J. Autoimmun. 29: 213–218
   PubMedGoogle Scholar
• Coutinho, A., M. D. Kazatchkine, and S. Avrameas. 1995. Natural autoantibodies. Curr. Opin. Immunol. 7: 812–818
   PubMed Web of Science ®Google Scholar
• Shoenfeld, Y., G. Twig, U. Katz, and Y. Sherer. 2008. Autoantibody explosion in antiphospholipid syndrome. J. Autoimmun. 30: 74–83
   PubMed Web of Science ®Google Scholar
• D'Ippolito, S., P. L. Meroni, T. Koike, et al. 2014. Obstetric antiphospholipid syndrome: a recent classification for an old defined disorder. Autoimmun. Rev. doi:10.1016/j.autrev.2014.05.004. [Epub ahead of print]
   Google Scholar