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Autoimmunity Volume 48, 2015 - Issue 2
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Full-Length Research Paper

Associations between Klinefelter’s syndrome and autoimmune diseases: English national record linkage studies

Olena O. SeminogUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, OX, UK and
,
Alla B. SeminogInstitute of Paediatrics, Obstetrics and Gynaecology, Academy of Medical Sciences of Ukraine, Kiev, Ukraine
,
David YeatesUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, OX, UK and
&
Michael J. GoldacreUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, OX, UK and Correspondence[email protected]
Pages 125-128 | Received 10 Feb 2014, Accepted 17 Sep 2014, Published online: 08 Oct 2014

References

  • Cooper, G. S., and B. C. Stroehla. 2003. The epidemiology of autoimmune diseases. Autoimmun. Rev. 2: 119–125
  • Whitacre, C. C. 2001. Sex differences in autoimmune disease. Nat. Immunol. 9: 777–780
  • Gleicher, N., and D. H. Barad. 2007. Gender as risk factor for autoimmune diseases. J. Autoimmun. 28: 1–6
  • Fish, E. N. 2008. The X-files in immunity: sex-based differences predispose immune responses. Nat. Rev. Immunol. 8: 737–744
  • Pennell, L. M., C. L. Galligan, and E. N. Fish. 2012. Sex affects immunity. J. Autoimmun. 38: 282–291
  • Invernizzi, P., S. Pasini, C. Selmi, et al. 2009. Female predominance and X chromosome defects in autoimmune diseases. J. Autoimmun. 33: 12–16
  • Invernizzi, P., S. Pasini, C. Selmi, et al. 2008. Skewing of X chromosome inactivation in autoimmunity. Autoimmunity. 41: 272–277
  • Goldacre, M. J., and O. O. Seminog. 2014. Turner syndrome and autoimmune diseases: record-linkage study. Arch. Dis. Child. 99: 71–73
  • Klinefelter, H. F., E. C. Reifenstein, and F. Albright. 1942. Syndrome characterized by gynecomastia, aspermatogenesis without A-Leydigism, and increased excretion of follicle-stimulating hormone. J. Clin. Endocrinol. 2: 615–627
  • Groth, K. A., A. Skakkebæk, C. Høst, et al. 2013. Klinefelter syndrome -A clinical update. J. Clin. Endocrinol. Metab. 98: 20–30
  • Takeuchi, Y., Y. Murata, J. Sintani, et al. 1999. Klinefelter's syndrome accompanied by mixed connective tissue disease and diabetes mellitus. Intern. Med. 38: 875–881
  • Gold, J., R. Goldacre, H. Maruszak, et al. 2014. HIV and lower risk of multiple sclerosis: beginning to unravel a mystery using a record-linked database study. J. Neurol. Neurosurg. Psychiatry. [Epub ahead of print]. doi:10.1136/jnnp-2014-307932
  • Bojesen, A., S. Juul, N. H. Birkebæk, and C. H. Gravholt. 2006. Morbidity in Klinefelter syndrome: a Danish register study based on hospital discharge diagnoses. J. Clin. Endocrinol. Metab. 91: 1254–1260
  • Rovenský, J. 2011. Rheumatic diseases and Klinefelter's syndrome. Autoimmun. Rev. 6: 33–36
  • Scofield, R. H., G. R. Bruner, B. Namjou, et al. 2008. Klinefelter's syndrome (47, XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome. Arthritis. Rheum. 8: 2511–2517
  • French, M. A., and P. Hughes. 1983. Systemic lupus erythematosus and Klinefelter's syndrome. Ann. Rheum. Dis. 42: 471–473
  • Stern, R., J. Fishman, H. Brusman, and H. Kunkel. 1977. Systemic lupus erythematosus associated with Klinefelter's syndrome. Arthritis. Rheum. 20: 18–22
  • Kota, S. K., L. K. Meher, S. Jammula, et al. 2012. Clinical profile of coexisting conditions in type 1 diabetes mellitus patients. Diabetes. Metab. Syndr. 6: 70–76
  • Swerdlow, A. J., C. D. Higgins, M. J. Shoemaker, et al. 2005. Mortality in patients with Klinefelter syndrom in Britain: a cohort study. J. Clin. Endocrinol. Metab. 90: 6516–6522
  • Vallotton, M., and A. Forbes. 1967. Autoimmunity in gonadal dysgenesis and Klinefelter's syndrome. Lancet. 289: 648–651
  • Bizzarro, A., G. Valentini, G. D. Martin, et al. 1987. Influence of testosterone therapy on clinical and immunological features of autoimmune diseases associated with Klinefelter’s syndrome. J. Clin. Endocrinol. Metab. 64: 32–36
  • Larizza, D., M. M. Bianchi, R. Lorini, et al. 1989. Autoimmunity, HLA, Gm and Km polymorphisms in Turner's syndrome. Autoimmunity. 4: 69–78
  • Wilson, R., C. E. Chu, M. D. Donaldson, et al. 1996. An increased incidence of thyroid antibodies in patients with Turner's syndrome and their first degree relatives. Autoimmunity. 25: 47–52
  • Huang, Q., A. Parfitt, D. M. Grennan, and N. Manolios. 1997. X-chromosome inactivation in monozygotic twins with systemic lupus erythematosus. Autoimmunity. 26: 85–93
  • Martin-Villa, J. M., A. Corell, J. T. Ramos-Amador, et al. 1999. Higher incidence of autoantibodies in X-linked chronic granulomatous disease carriers: random X-chromosome inactivation may be related to autoimmunity. Autoimmunity. 31: 261–264

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