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Original Article

Interleukin-17 is a critical target for the treatment of ankylosing enthesitis and psoriasis-like dermatitis in mice

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Pages 259-266 | Received 18 Jun 2014, Accepted 05 Oct 2014, Published online: 29 Oct 2014

References

  • Braun, J., and J. Sieper. (2007). Ankylosing spondylitis. Lancet. 369: 1379–1390
  • Ritchlin, C. (2007). Psoriatic disease – from skin to bone. Nat. Clin. Pract. Rheumatol. 3: 698–706
  • Braun, J., J. Brandt, J. Listing, et al. (2002). Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial. Lancet. 359: 1187–1193
  • Davis J. C. Jr, D. Van Der Heijde, J. Braun, et al. (2003). Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis: a randomized, controlled trial. Arthritis. Rheum. 8: 3230–3236
  • Van den Bosch, F., E. Kruithof, D. Baeten, et al. (2000). Effects of a loading dose regimen of three infusions of chimeric monoclonal antibody to tumour necrosis factor alpha (infliximab) in spondyloarthropathy: an open pilot study. Ann. Rheum. Dis. 9: 428–433
  • Mease, P. J., B. S. Goffe, J. Metz, et al. (2000). Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet 356: 385–390
  • Haroon, N., R. D. Inman, T. J. Learch, et al. (2013). The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis. Arthritis. Rheum. 65: 2645–2654
  • Wendling, D., J. P. Cedoz, E. Racadot, and G. Dumoulin. (2007). Serum IL-17, BMP-7, and bone turnover markers in patients with ankylosing spondylitis. Joint Bone Spine 74: 304–305
  • Mei, Y., F. Pan, J. Gao, et al. (2011). Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis. Clin. Rheumatol. 30: 269–273
  • Jandus, C., G. Bioley, J. P. Rivals, et al. (2008). Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum. 58: 2307–2317
  • Shen, H., J. C. Goodall, and J. S. Hill Gaston. (2009). Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum. 60: 1647–1656
  • Kenna, T. J., S. I. Davidson, R. Duan, et al. (2012). Enrichment of circulating IL-17-secreting IL-23 receptor-positive γδ T cells in patients with active ankylosing spondylitis. Arthritis Rheum. 64: 1420–1429
  • Noordenbos, T., N. Yeremenko, I. Gofita, et al. (2012). Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. Arthritis Rheum. 64: 99–109
  • Appel, H., R. Maier, P. Wu, et al. (2011). Analysis of interleukin-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17 mediated adaptive immune response. Arthritis Res. Ther. 13: R95
  • Raychaudhuri, S. P., S. K. Raychaudhuri, and M. C. Genovese. (2012). IL-17 receptor and its functional significance in psoriatic arthritis. Mol. Cell. Biochem. 359: 419–429
  • Végvári, A., Z. Szabó, S. Szántó, et al. (2009). The genetic background of ankylosing spondylitis. Joint Bone Spine 76: 623–628
  • Fitzgerald, O., and R. Winchester. (2009). Psoriatic arthritis: from pathogenesis to therapy. Arthritis Res. Ther. 11: 214–222
  • Turner, M. J., M. L. Delay, S. Bai, et al. (2007). HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum. 56: 215–223
  • DeLay, M. L., M. J. Turner, E. I. Klenk, et al. (2009). HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats. Arthritis. Rheum. 60: 2633–2643
  • Bowes, J., and A. Barton. (2010). The genetics of psoriatic arthritis: lessons from genome-wide association studies. Discov. Med. 10: 177–183
  • Papp, K. A., R. G. Langley, B. Sigurgeirsson, et al. (2013). Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study. Br. J. Dermatol. 168: 412–421
  • McInnes, I. B., J. Sieper, J. Braun, et al. (2014). Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann. Rheum. Dis. 73: 349–356
  • Baeten, D., X. Baraliakos, J. Braun, et al. (2013). Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial. Lancet. 382: 1705–1713
  • Oishi, H., T. Miyazaki, S. Mizuki, et al. (2005). Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice. Arthritis. Rheum. 52: 959–966
  • Corthay, A., A. S. Hansson, and R. Holmdahl. (2000). T lymphocytes are not required for the spontaneous development of entheseal ossification leading to marginal ankylosis in the DBA/1 mouse. Arthritis. Rheum. 43: 844–851
  • Lories, R. J., I. Derese, C. de Bari, and F. P. Luyten. (2007). Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis. Rheum. 56: 489–497
  • Lories, R. J., P. Matthys, K. de Vlam, et al. (2004). Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann. Rheum. Dis. 63: 595–598
  • Leigh, I. M., H. Navsaria, P. E. Purkis, et al. (1995). Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br. J. Dermatol. 133: 501–511
  • Eckert, R. L., A. M. Broome, M. Ruse, et al. (2004). S100 proteins in the epidermis. J. Invest. Dermatol. 123: 23–33
  • Wilson, N. J., K. Boniface, J. R. Chan, et al. (2007). Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 8: 950–957
  • Ballow, M. (2011). The IgG molecule as a biological immune response modifier: mechanisms of action of intravenous immune serum globulin in autoimmune and inflammatory disorders. J. Allergy. Clin. Immunol. 127: 315–23
  • Lin, A. M., C. J. Rubin, R. Khandpur, et al. (2011). Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J. Immunol. 187: 490–500
  • Res, P. C., G. Piskin, O. J. de Boer, et al. (2010). Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS. One. 5: e14108
  • Crellin, N. K., S. Trifari, C. D. Kaplan, et al. (2010). Human NKp44 + IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells. J. Exp. Med. 207: 281–290
  • McGonagle, D., Z. Ash, L. Dickie, et al. (2011). The early phase of psoriatic arthritis. Ann. Rheum. Dis. 70: i71–i76
  • Semprini, S., F. Capon, A. Tacconelli, et al. (2002). Evidence for differential S100 gene over-expression in psoriatic patients from genetically heterogeneous pedigrees. Hum. Genet. 111: 310–313
  • Pattison, E., B. J. Harrison, C. E. Griffiths, et al. (2008). Environmental risk factors for the development of psoriatic arthritis: results from a case–control study. Ann. Rheum. Dis. 67: 672–676
  • Stankler, L. (1969). An experimental investigation on the site of skin damage inducing the Koebner reaction in psoriasis. Br. J. Dermatol. 81: 534–535
  • Iwakura, Y., H. Ishigame, S. Saijo, and S. Nakae. (2011). Functional specialization of interleukin-17 family members. Immunity 34: 149–162
  • Charles, P., M. J. Elliott, D. Davis, et al. (1999). Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J. Immunol. 163: 1521–1528
  • Ma, H. L., S. Liang, J. Li, et al. (2008). IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J. Clin. Invest. 118: 597–607
  • Smith, E., M. A. Stark, A. Zarbock, et al. (2008). IL-17A inhibits the expansion of IL-17A-producing T cells in mice through “short-loop” inhibition via IL-17 receptor. J. Immunol. 181: 1357–1364
  • Algood, H. M., S. S. Allen, M. K. Washington, et al. (2009). Regulation of gastric B cell recruitment is dependent on IL-17 receptor a signaling in a model of chronic bacterial infection. J. Immunol. 183: 5837–5846

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