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Original Article

Immunization of mice with a peptide derived from the HTLV-1 TAX1BP1 protein induces cross-reactive antibodies against aquaporin 4

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Pages 453-459 | Received 08 Jan 2015, Accepted 03 Jul 2015, Published online: 14 Aug 2015

References

  • Jarius, S., and B. Wildemann. 2010. AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance. Nat. Rev. Neurol. 6: 383–392
  • Lennon, V. A., T. J. Kryzer, S. J. Pittock, et al. 2005. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J. Exp. Med. 202: 473–477
  • Lennon, V. A., D. M. Wingerchuk, T. J. Kryzer, et al. 2004. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 364: 2106–2112
  • Wingerchuk, D. M., V. A. Lennon, C. F. Lucchinetti, et al. 2007. The spectrum of neuromyelitis optica. Lancet Neurol. 6: 805–815
  • Iorio, R., J. P. Fryer, S. R. Hinson, et al. 2013. Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays. J. Autoimmun. 40: 21–27
  • Kampylafka, E. I., J. G. Routsias, H. Alexopoulos, et al. 2011. Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes. J. Autoimmun. 36: 221–227
  • Marnetto, F., B. Hellias, L. Granieri, et al. 2009. Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with neuromyelitis optica. J. Neuroimmunol. 217: 74–79
  • Nicchia, G. P., M. Mastrototaro, A. Rossi, et al. 2009. Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodies. Glia 57: 1363–1373
  • Pisani, F., M. Mastrototaro, A. Rossi, et al. 2011. Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding. J. Biol. Chem. 286: 9216–9224
  • Tani, T., K. Sakimura, M. Tsujita, et al. 2009. Identification of binding sites for anti-aquaporin 4 antibodies in patients with neuromyelitis optica. J. Neuroimmunol. 211: 110–113
  • Chin, K. T., A. C. Chun, Y. P. Ching, et al. 2007. Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1. Cancer Res. 67: 1072–1081
  • Gatza, M. L., J. C. Watt, and S. J. Marriott. 2003. Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades. Oncogene 22: 5141–5149
  • Izumo, S. 2010. Neuropathology of HTLV-1-associated myelopathy (HAM/TSP). Neuropathology 30: 480–485
  • Koga, M., T. Takahashi, M. Kawai, et al. 2009. Neuromyelitis optica with HTLV-1 infection: different from acute progressive HAM? Intern. Med. 48: 1157–1159
  • Olindo, S., M. Bonnan, H. Merle, et al. 2010. Neuromyelitis optica associated with subacute human T-lymphotropic virus type 1 infection. J. Clin. Neurosci. 17: 1449–1451
  • Symmonds, M., N. Nirmalananthan, G. P. Taylor, et al. 2012. Devastating aquaporin-4 and HTLV-1-associated necrotizing encephalopathy. J. Neurol. 259: 2732–2735
  • Delgado, S. R., W. A. Sheremata, A. D. Brown, and M. McCarthy. 2010. Human T-lymphotropic virus type I or II (HTLV-I/II) associated with recurrent longitudinally extensive transverse myelitis (LETM): two case reports. J. Neurovirol. 16: 249–253
  • Slavin, A., L. Kelly-Modis, M. Labadia, et al. 2010. Pathogenic mechanisms and experimental models of multiple sclerosis. Autoimmunity 43: 504–513
  • Iyer, A., L. Elsone, R. Appleton, and A. Jacob. 2014. A review of the current literature and a guide to the early diagnosis of autoimmune disorders associated with neuromyelitis optica. Autoimmunity 47: 154–161
  • Jarius, S., and B. Wildemann. 2013. Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature. Brain Pathol. 23: 661–683
  • Nagelhus, E. A., and O. P. Ottersen. 2013. Physiological roles of aquaporin-4 in brain. Physiol. Rev. 93: 1543–1562
  • Irani, S. R., J. M. Gelfand, A. Al-Diwani, and A. Vincent. 2014. Cell-surface central nervous system autoantibodies: clinical relevance and emerging paradigms. Ann. Neurol. 76: 168–184
  • Alexopoulos, H., and M. C. Dalakas. 2013. Immunology of stiff person syndrome and other GAD-associated neurological disorders. Expert Rev. Clin. Immunol. 9: 1043–1053
  • Routsias, J. G., P. G. Vlachoyiannopoulos, and A. G. Tzioufas. 2006. Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response. Crit. Rev. Clin. Lab. Sci. 43: 203–248
  • Alexopoulos, H., E. I. Kampylafka, I. Chatzi, et al. 2013. Reactivity to AQP4 epitopes in relapsing-remitting multiple sclerosis. J. Neuroimmunol. 260: 117–120
  • Arellano, B., R. Hussain, T. Zacharias, et al. 2012. Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch. Neurol. 69: 1125–1131
  • Kalluri, S. R., V. Rothhammer, O. Staszewski, et al. 2011. Functional characterization of aquaporin-4 specific T cells: towards a model for neuromyelitis optica. PLoS One 6: e16083
  • Vinuesa, C. G., S. G. Tangye, B. Moser, and C. R. Mackay. 2005. Follicular B helper T cells in antibody responses and autoimmunity. Nature Rev. Immunol. 5: 853–865
  • Doucas, V., and R. M. Evans. 1999. Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling. Proc. Natl. Acad. Sci. USA 96: 2633–2638
  • Yoshida, M. 2001. Multiple viral strategies of HTLV-1 for dysregulation of cell growth control. Ann. Rev. Immunol. 19: 475–496
  • Grant, C., K. Barmak, T. Alefantis, et al. 2002. Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation. J. Cell. Physiol. 190: 133–159
  • Jeang, K. T., S. G. Widen, O. J. T. Semmes, and S. H. Wilson. 1990. HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene. Science (NY) 247: 1082–1084
  • Szymocha, R., H. Akaoka, M. Dutuit, et al. 2000. Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha. J. Virol. 74: 6433–6441
  • Zaninovic, V. 2004. Possible etiologies for tropical spastic paraparesis and human T lymphotropic virus I-associated myelopathy. Braz. J. Med. Biol. Res. 37: 1–12
  • von Glehn, F., S. Jarius, A. C. Penalva de Oliveira, et al. 2012. Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy. PLoS One 7: e39372
  • Routsias, J. G., and A. G. Tzioufas. 2010. B-cell epitopes of the intracellular autoantigens Ro/SSA and La/SSB: tools to study the regulation of the autoimmune response. J. Autoimmun. 35: 256–264
  • Jones, R. E., D. Bourdette, N. Moes, et al. 2003. Epitope spreading is not required for relapses in experimental autoimmune encephalomyelitis. J. Immunol. 170: 1690–1698
  • Hassin-Baer, S., E. D. Kirson, L. Shulman, et al. 2004. Stiff-person syndrome following West Nile fever. Arch. Neurol. 61: 938–941

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