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Original Article

Adipose-derived mesenchymal stem cells from infrapatellar fat pad of patients with rheumatoid arthritis and osteoarthritis have comparable immunomodulatory properties

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Pages 124-131 | Received 10 Jul 2015, Accepted 23 Oct 2015, Published online: 29 Dec 2015

References

  • Zuk, P. A., M. Zhu, P. Ashjian, et al. 2002. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell. 13: 4279–4295
  • Yoo, K. H., I. K. Jang, M. W. Lee, et al. 2009. Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. Cell Immunol. 259: 150–156
  • Uccelli, A., G. Mancardi, and S. Chiesa. 2008. Is there a role for mesenchymal stem cells in autoimmune diseases? Autoimmunity. 41: 592–595
  • Ra, J. C., S. K. Kang, I. S. Shin, et al. 2011. Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells. J. Transl. Med. 9: 181
  • Kokai, L. E., K. Marra, and J. P. Rubin. 2014. Adipose stem cells: biology and clinical applications for tissue repair and regeneration. Transl. Res. 163: 399–408
  • Djouad, F., C. Bouffi, S. Ghannam, et al. 2009. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat. Rev. Rheumatol. 5: 392–399
  • Leto Barone, A. A., S. Khalifian, W. P. Lee, and G. Brandacher. 2013. Immunomodulatory effects of adipose-derived stem cells: fact or fiction? Biomed. Res. Int. 2013: 383685
  • Crop, M. J., C. C. Baan, S. S. Korevaar, et al. 2010. Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells. Clin. Exp. Immunol. 162: 474–486
  • Waterman, R. S., S. L. Tomchuck, S. L. Henkle, and A. M. Betancourt. 2010. A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. PLoS One. 5: e10088
  • Delarosa, O., W. Dalemans, and E. Lombardo. 2012. Toll-like receptors as modulators of mesenchymal stem cells. Front. Immunol. 3: 182
  • Boissier M, S. L., Challal S. 2012. Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. J. Autoimmun. 39: 222–228
  • Brennan, F. M., and I. B. McInnes. 2008. Evidence that cytokines play a role in rheumatoid arthritis. J. Clin. Invest. 118: 3537–3545
  • Neurath, M. F., and S. Finotto. 2011. IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev. 22: 83–89
  • Barksby, H. E., S. R. Lea, P. M. Preshaw, and J. J. Taylor. 2007. The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin. Exp. Immunol. 149: 217–225
  • Azizi, G., F. Jadidi-Niaragh, and A. Mirshafiey. 2013. Th17 Cells in immunopathogenesis and treatment of rheumatoid arthritis. Int. J. Rheum. Dis. 16: 243–253
  • Liang, J., X. Li, H. Zhang, et al. 2012. Allogeneic mesenchymal stem cells transplantation in patients with refractory RA. Clin. Rheumatol. 31: 157–161
  • Wang, L., L. Wang, X. Cong, et al. 2013. Human umbilical cord mesenchymal stem cell therapy for patients with active rheumatoid arthritis: safety and efficacy. Stem Cells Dev. 22: 3192–3202
  • Gonzalez, M. A., E. Gonzalez-Rey, L. Rico, et al. 2009. Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum. 60: 1006–1019
  • Chen, B., J. Hu, L. Liao, et al. 2010. Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin. Exp. Immunol. 159: 292–302
  • Kehoe, O., A. Cartwright, A. Askari, et al. 2014. Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis. J. Transl. Med. 12: 157
  • Papadopoulou, A., M. Yiangou, E. Athanasiou, et al. 2012. Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis. Ann. Rheum. Dis. 71: 1733–1740
  • Liu, Y., J. Wu, Y. Zhu, and J. Han. 2014. Therapeutic application of mesenchymal stem cells in bone and joint diseases. Clin. Exp. Med. 14: 13–24
  • Berenbaum, F. 2013. Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!). Osteoarthritis Cartilage. 21: 16–21
  • Wilson, A., P. E. Butler, and A. M. Seifalian. 2011. Adipose-derived stem cells for clinical applications: a review. Cell Prolif. 44: 86–98
  • Caulfield, J. P., A. Hein, S. M. Helfgott, et al. 1988. Intraarticular injection of arthritogenic factor causes mast cell degranulation, inflammation, fat necrosis, and synovial hyperplasia. Lab Invest. 59: 82–95
  • Clockaerts, S., Y. M. Bastiaansen-Jenniskens, J. Runhaar, et al. 2010. The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review. Osteoarthritis Cartilage. 18: 876–882
  • Skalska, U., E. Kontny, M. Prochorec-Sobieszek, and W. Maslinski. 2012. Intra-articular adipose-derived mesenchymal stem cells from rheumatoid arthritis patients maintain the function of chondrogenic differentiation. Rheumatology (Oxford). 51: 1757–1764
  • Skalska, U., M. Prochorec-Sobieszek, and E. Kontny. 2014. Osteoblastic potential of infrapatellar fat pad-derived mesenchymal stem cells from rheumatoid arthritis and osteoarthritis patients. Int. J. Rheum. Dis. Epub ahead of print. doi: 10.1111/1756-185X.12368
  • Kontny, E., A. Grabowska, J. Kowalczewski, et al. 1999. Taurine chloramine inhibition of cell proliferation and cytokine production by rheumatoid arthritis fibroblast-like synoviocytes. Arthritis Rheum. 42: 2552–2560
  • van Buul, G. M., E. Villafuertes, P. K. Bos, et al. 2012. Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture. Osteoarthritis Cartilage. 20: 1186–1196
  • Murphy, M. B., K. Moncivais, and A. I. Caplan. 2013. Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine. Exp. Mol. Med. 45: e54
  • Le Blanc, K., I. Rasmusson, C. Gotherstrom, et al. 2004. Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes. Scand. J. Immunol. 60: 307–315
  • Glennie, S., I. Soeiro, P. J. Dyson, et al. 2005. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood. 105: 2821–2827
  • Zafranskaya, M., D. Nizheharodava, M. Yurkevich, et al. 2013. PGE2 contributes to in vitro MSC-mediated inhibition of non-specific and antigen-specific T cell proliferation in MS patients. Scand. J. Immunol. 78: 455–462
  • Ghannam, S., C. Bouffi, F. Djouad, et al. 2010. Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications. Stem Cell Res. Ther. 1: 2
  • Kastrinaki, M. C., P. Sidiropoulos, S. Roche, et al. 2008. Functional, molecular and proteomic characterisation of bone marrow mesenchymal stem cells in rheumatoid arthritis. Ann. Rheum. Dis. 67: 741–749
  • Jones, E. A., A. English, K. Henshaw, et al. 2004. Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis. Arthritis Rheum. 50: 817–827
  • Bocelli-Tyndall, C., L. Bracci, G. Spagnoli, et al. 2007. Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro. Rheumatology (Oxford). 46: 403–408
  • Gonzalez-Rey, E., M. A. Gonzalez, N. Varela, et al. 2010. Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann. Rheum. Dis. 69: 241–248
  • Kim, N., and S. G. Cho. 2013. Clinical applications of mesenchymal stem cells. Korean J. Intern. Med. 28: 387–402
  • Furst, D. E., and P. Emery. 2014. Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets. Rheumatology (Oxford). 53: 1560–1569
  • Sun, Y., W. Deng L. Geng, L. et al. 2015. Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J. Immunol. Res. 2015: 284215
  • Noack, M., Thaim N, Miossec P. 2014. Interaction between fibroblasts and T lymphocytes is needed for IL-17 secretion and Th17 differentiation requires T cell activation [abstract]. Ann. Rheum. Dis. 73: A29
  • Kontny, E., and M. Prochorec-Sobieszek. 2013. Articular adipose tissue resident macrophages in rheumatoid arthritis patients: potential contribution to local abnormalities. Rheumatology (Oxford). 52: 2158–2167
  • Mochizuki, T., T. Muneta, Y. Sakaguchi, et al. 2006. Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fat-derived cells: distinguishing properties of mesenchymal stem cells in humans. Arthritis Rheum. 54: 843–853
  • Peptan, I. A., L. Hong, and J. J. Mao. 2006. Comparison of osteogenic potentials of visceral and subcutaneous adipose-derived cells of rabbits. Plast. Reconstr. Surg. 117: 1462–1470
  • Ma, S., N. Xie, W. Li, et al. 2014. Immunobiology of mesenchymal stem cells. Cell Death Differ. 21: 216–225

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