References
- Hetz, C., F. Martinon, D. Rodriguez, and L. H. Glimcher. 2012. The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha. Physiol. Rev. 91: 1219–1243
- Harding, H. P., Y. Zhang, A. Bertolotti, et al. 2000. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 5: 897–904
- Harding, H. P., I. Novoa, Y. Zhang, et al. 2000. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6: 1099–1108
- Harding, H. P., Y. Zhang, H. Zeng, et al. 2003. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell 11: 619–633
- Novoa, I., H. Zeng, H. P. Harding, and D. Ron. 2001. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153: 1011–1022
- Novoa, I., Y. Zhang, H. Zeng, et al. 2003. Stress-induced gene expression requires programmed recovery from translational repression. EMBO J. 22: 1180–1187
- Janssens, S., B. Pulendran, and B. N. Lambrecht. 2014. Emerging functions of the unfolded protein response in immunity. Nat. Immunol. 15: 910–919
- Martinon, F., and L. H. Glimcher. 2011. Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. Curr. Opin. Immunol. 23: 35–40
- Iwakoshi, N. N., A. H. Lee, P. Vallabhajosyula, et al. 2003. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat. Immunol. 4: 321–329
- Iwakoshi, N. N., M. Pypaert, and L. H. Glimcher. 2007. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J. Exp. Med. 204: 2267–2275
- Ulianich, L., G. Terrazzano, M. Annunziatella, et al. 2011. ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity. Biochim. Biophys. Acta 1812: 431–438
- Ozcan, L. 2012. Endoplasmic reticulum stress in cardiometabolic disorders. Curr. Atheroscler. Rep. 14: 469–475
- Lin, W., and B. Popko. 2009. Endoplasmic reticulum stress in disorders of myelinating cells. Nat. Neurosci. 12: 379–385
- Wang, S., and R. J. Kaufman. 2012. The impact of the unfolded protein response on human disease. J. Cell Biol. 197: 857–867
- Kaser, A., A. H. Lee, A. Franke, et al. 2008. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 134: 743–756
- McInnes, I. B., and G. Schett. 2011. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365: 2205–2219
- Burska, A., M. Boissinot, and F. Ponchel. 2014. Cytokines as biomarkers in rheumatoid arthritis. Mediators Inflamm. 2014: 545493
- Ingegnoli, F., R. Castelli, and R. Gualtierotti. 2013. Rheumatoid factors: clinical applications. Dis. Markers 35: 727–734
- Aletaha, D., T. Neogi, A. J. Silman, et al. 2010. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 62: 2569–2581
- Majka, D. S., K. D. Deane, L. A. Parrish, et al. 2008. Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis. Ann. Rheum. Dis. 67: 801–807
- Clavarino, G., N. Claudio, A. Dalet, et al. 2012. Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells. Proc. Natl Acad. Sci. U. S. A. 109: 3006–3011
- Clavarino, G., N. Claudio, T. Couderc, et al. 2012. Induction of GADD34 is necessary for dsRNA-dependent interferon-beta production and participates in the control of Chikungunya virus infection. PLoS Pathog. 8: e1002708
- Claudio, N., A. Dalet, E. Gatti, and P. Pierre. 2013. Mapping the crossroads of immune activation and cellular stress response pathways. EMBO J. 32: 1214–1224
- Park, Y. J., S. A. Yoo, and W. U. Kim. 2014. Role of endoplasmic reticulum stress in rheumatoid arthritis pathogenesis. J. Kor. Med. Sci. 29: 2–11
- Lee, Y. Y., R. C. Cevallos, and E. Jan. 2009. An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation. J. Biol. Chem. 284: 6661–6673
- Brush, M. H., and S. Shenolikar. 2008. Control of cellular GADD34 levels by the 26S proteasome. Mol. Cell. Biol. 28: 6989–7000
- Zhou, W., K. Jeyaraman, P. Yusoff, and S. Shenolikar. 2013. Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. J. Biol. Chem. 288: 33146–33155
- Yanaba, K., J. D. Bouaziz, T. Matsushita, et al. 2008. B-lymphocyte contributions to human autoimmune disease. Immunol. Rev. 223: 284–299
- Brewer, J. W., and L. M. Hendershot. 2005. Building an antibody factory: a job for the unfolded protein response. Nat. Immunol. 6: 23–29
- Reimold, A. M., N. N. Iwakoshi, J. Manis, et al. 2001. Plasma cell differentiation requires the transcription factor XBP-1. Nature 412: 300–307
- Connor, A. M., N. Mahomed, R. Gandhi, et al. 2012. TNFalpha modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts. Arthritis Res. Ther. 14: R62
- Burska, A. N., K. Roget, M. Blits, et al. 2014. Gene expression analysis in RA: towards personalized medicine. Pharmacogenomics J. 14: 93–106
- Colmegna, I., B. R. Ohata, and H. A. Menard. 2012. Current understanding of rheumatoid arthritis therapy. Clin. Pharmacol. Ther. 91: 607–620
- Tsaytler, P., H. P. Harding, D. Ron, and A. Bertolotti. 2011. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 332: 91–94
- Wang, L., B. Popko, E. Tixier, and R. P. Roos. 2014. Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis. Neurobiol. Dis. 71C: 317324