The CD5⁺ B Cell: A B Cell Lineage with a Central role in Autoimmune Disease?

References

• Jones N H, Clabby M L, Dialynas D P, Huang H-JS, Herzenberg L A, Strominger J L. Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/leu 1. Nature 1986; 323: 346–349
   PubMed Web of Science ®Google Scholar
• Huang H-JS, Jones N H, Strominger J L, Herzenberg L A. Molecular cloning of ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu 1/T1 (CD5). Proc Natl Acad Sci USA 1987; 84: 204–208
   PubMed Web of Science ®Google Scholar
• Cantor H, Boyse E A. Functional subclasses of T lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiation process independent of antigen. J Exp Med 1975; 141: 1376–1389
   PubMed Web of Science ®Google Scholar
• Ledbetter J A, Herzenberg L A. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunological Rev 1979; 47: 63–90
   PubMed Web of Science ®Google Scholar
• Ledbetter J A, Rouse R V, Micklem H S, Herzenberg L A. T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views. J Exp Med 1980; 152: 280–295
   PubMed Web of Science ®Google Scholar
• Reinherz E L, Kung P C, Goldstein G, Schlossman S F. A monoclonal antibody with selective reactivity with functionally mature human thymocytes and all peripheral human T cells. J Immunol 1979; 123: 1312–1317
   PubMed Web of Science ®Google Scholar
• Engelman E G, Warnke R, Fox R I, Dilley J, Benike C J, Levy R. Studies of a human T lymphocyte antigen recognised by a monoclonal antibody. Proc Natl Acad Sci USA 1981; 78: 1791–1795
   Google Scholar
• Ledbetter J A, Evans R L, Lipinski M, Cunningham-Rundles C, Good R A, Herzenberg L A. Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man. J Exp Med 1981; 153: 310–323
   PubMed Web of Science ®Google Scholar
• Lanier L L, Warner N L, Ledbetter J A, Herzenberg L A. Expression of Lyt-I antigen on certain murine B cell lymphomas. J Exp Med 1981; 153: 998–1003
   PubMed Web of Science ®Google Scholar
• Wang C Y, Good R A, Ammirati P, Dymbort G, Evans R L. Identification of a p69,71 complex expressed on human T cells sharing determinants with B-type chronic lymphocytic leukaemic cells. J Exp Med 1980; 151: 1539–1544
   PubMed Web of Science ®Google Scholar
• Royston I, Majda J A, Baird S M, Meserve B L, Griffiths J C. Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukaemic cells bearing surface immunoglobulin. J Immunol 1980; 125: 725–731
   PubMed Web of Science ®Google Scholar
• Caligaris-Cappio F, Gobbi M, Bofill M, Janossy G. Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukaemia. J Exp Med 1982; 155: 623–628
   PubMed Web of Science ®Google Scholar
• Gadol N, Ault K A. Phenotypic and functional characterisation of human leu-1 (CD5) B cells. Immunological Reviews 1986; 93: 23–34
   PubMed Web of Science ®Google Scholar
• Bofill M, Janossy G, Janossa M, Burford G D, Seymour G J, Wernet P, Kelemen E. Human B cell development. II. Subpopulations in the human fetus. J Immunol 1985; 134: 1531–1538
   PubMed Web of Science ®Google Scholar
• Antin J H, Emerson S G, Martin P, Gadol N, Ault K A. Leu-1 (CD5) B cells. A major lymphoid subpopulation in human fetal spleen: phenotypic and functional studies. J Immunol 1986; 136: 505–510
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Parks D R, Herzenberg L A. The “ly-1 B” cell subpopulation in normal, immunodefective, and autoimmune mice. J Exp Med 1983; 157: 202–218
   PubMed Web of Science ®Google Scholar
• Manohar V, Brown E, Leiserson W M, Chused T M. Expression of lyt-1 by a subset of B lymphocytes. J Immunol 1982; 129: 532–538
   PubMed Web of Science ®Google Scholar
• Hardy R R, Hayakawa K. Development and physiology of ly-1 B and its human homologue, leu-1 B. Immunological Reviews 1986; 93: 53–79
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Herzenberg L A. Peritoneal ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression. Eur J Immunol 1986; 16: 450–456
   PubMed Web of Science ®Google Scholar
• Herzenberg L A, Stall A M, Lalor P A, Sidman C, Moore W A, Parks D R, Herzenberg L A. The ly-1 B cell lineage. Immunological Reviews 1986; 93: 81–102
   PubMed Web of Science ®Google Scholar
• Sherr D H, Ju S-T. Idiotype-specific helper cells (BH) express immunoglobulin markers and employ T cell function-associated molecules. J Immunol 1986; 137: 3406–3413
   Google Scholar
• Hardy R R, Dangl J L, Hayakawa K, Jager G, Herzenberg L A, Herzenberg L A. Frequent lambda light chain gene rearrangement and expression in a ly-1 B lymphoma with a productive kappa allele. Proc Natl Acad Sci USA 1986; 83: 1438–1442
   Google Scholar
• Kleinfeld R, Hardy R R, Tarlinton D, Dangl J, Herzenberg L A, Weigert M. Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a ly-1+ B-cell lymphoma. Nature 1987; 322: 843–846
   Google Scholar
• Herzenberg L, Stall A M, Braun J, Weaver D, Baltimore D, Herzenberg La, Grosschedl R. Depletion of the predominant B-cell population in immunoglobulin mu heavy-chain transgenic mice. Nature 1987; 329: 71–73
   PubMedGoogle Scholar
• Burkly L C, Nikolic J, Wortis H H. T cell regulation of light chain expression: preferential enhancement of Igk in a primary thymus-dependent response does not require affinity-based selection. J Immunol 1985; 135: 1573–1576
   Google Scholar
• Sidman C L, Shultz L D, Hardy R R, Hayakawa K, Herzenberg L A. Production of immunoglobulin isotypes by ly-1+ B cells in viable motheaten and normal mice. Science 1986; 232: 1423–1425
   PubMed Web of Science ®Google Scholar
• Perlmutter R M, Nahm M, Stein K E, Slack J, Zitron I, Paul W E, Davie J M. Immunoglobulin subclass-specific immunodeficiency in mice with an X-linked B-lymphocyte defect. J Exp Med 1979; 149: 993–998
   PubMed Web of Science ®Google Scholar
• Burkly L C, Zaugg R, Eisen H N, Wortis H H. Influence of the nude and X-linked immune deficiency genes on expression of kappa and lambda light chains. Eur J Immunol 1982; 12: 1033–1039
   Google Scholar
• Casali P, Burastero S E, Nakamura M, Inghirami G, Notkins A L. Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to leu-1+ B-cell subset. Science 1987; 236: 77–80
   PubMed Web of Science ®Google Scholar
• Hardy R R, Hayakawa K, Shimizu M, Yamasaki K, Kishimoto T. Rheumatoid factor secretion from human leu-1+ B cells. Science 1987; 236: 81–83
   PubMed Web of Science ®Google Scholar
• Okumura K, Hayakawa K, Tada T. Cell-to-cell interaction controlled by immunoglobulin genes. J Exp Med 1982; 156: 443–453
   Google Scholar
• Sherr D H, Dorf M E. An idiotype-specific helper population that bears immunoglobulin, Ia, and lyt-1 determinants. J Exp Med 1984; 159: 1189–1200
   PubMedGoogle Scholar
• Sherr D H, Dorf M E. H-2-restricted helper activity mediated by immunoglobuliun-bearing lymphocytes. J Immunol 1985; 134: 2084–2089
   Google Scholar
• Sherr D H, Braun J, Dorf M E. Idiotype-speciflc ly-1 B cell-mediated helper activity: hybridomas that produce anti-idiotype antibody and nonimmunoglobulin lymphokine(s). J Immunol 1987; 138: 2057–2062
   Google Scholar
• Brooks K H, Uhr J W, Vitetta E S. A B cell growth factor-like activity is secreted by cloned neoplastic B cells. J Immunol 1984; 133: 3133–3137
   Google Scholar
• Davidson W F, Fredrickson T N, Rudikoff E K, Coffman R L, Hartley J W, Morse H C. A unique series of lymphomas related to the ly-1+ lineage of B lymphocyte differentiation. J Immunol 1984; 133: 744–753
   PubMed Web of Science ®Google Scholar
• Sidman C L, Marshall J D, Masiello N C, Roths J B, Shultz L D. Novel B cell maturation factor from spontaneously autoimmune viable motheaten mice. Proc Natl Acad Sci USA 1984; 81: 7199–7202
   PubMed Web of Science ®Google Scholar
• Inada T, Yamaoto H, Bitoh S, Fujimoto S, Hamaoka T. Detection and characterisation of idiotype-speciflc enhancing cells generated in mice immunised with idiotype. J Immunol 1982; 129: 2069–2073
   Google Scholar
• Yamaoto H, Bitoh S, Fujimoto S. Regulation of immune responses via genetically-restricted cellular interactions. I. Augmentation of antibody responses by idiotype-speciflc enhancing B lymphocytes. J Immunol 1984; 133: 2882–2887
   Google Scholar
• Braun J. Spontaneous in vitro occurrence and long-term culture of murine B lymphoblast cell lines. J Immunol 1983; 130: 2113–2116
   PubMedGoogle Scholar
• Braun J, Citri Y, Baltimore D, Forouzanpour F, King L, Teheranizadeh K., et al. B-ly 1 cells: immortal ly-1+ B lymphocyte cell lines spontaneously arising in murine splenic cultures. Immunological Reviews 1986; 93: 5–21
   Google Scholar
• Pennell C A, Arnold L A, Lutz P M, LoCascio N J, Willougby P B, Haughton G. Cross-reactive idiotypes and common antigen binding specificities expressed by a series of murine B-cell lymphomas. Proc Natl Acad Sci USA 1985; 82: 3799–3803
   Google Scholar
• Haughton G, Arnold L W, Bishop G A, Mercolino T J. The CH series of murine B cell lymphomas: neoplastic analogues of ly-1+ normal B cells. Immunological Reviews 1986; 93: 35–51
   PubMedGoogle Scholar
• MacLennan I CM, Gray D, Kumaratne D S, Bazin H. The lymphocytes of splenic marginal zones: a distinct B cell lineage. Immunol Today 1982; 3: 305–307
   PubMedGoogle Scholar
• Yong-Jun L, Lortan J E, Oldfield S, MacLennan I CM. CBA/N mice have phenotypically normal marginal zone B cells. Proceedings of the ninth international conference on lymphatic tissues and germinal centres in immune reactions. 1987. Plenum Publishing Corporation, Oslo, 9, in press
   Google Scholar
• Mosier D E, Zitron I M, Mond J J, Scher I, Paul W E. Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes. Immunological Rev 1977; 37: 89–104
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Honda M, Herzenberg L A, Steinberg A D, Herzenberg L A. Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies. Proc Natl Acad Sci USA 1984; 81: 2494–2498
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Herzenberg L A, Herzenberg L A. Progenitors for ly-1 B cells are distinct from progenitors for other B cells. J Exp Med 1985; 161: 1554–1568
   PubMed Web of Science ®Google Scholar
• Antin J H, Ault K A, Rappeport J M, Smith B R. B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct subpopulation of B lymphocytes. J Clin Invest 1987; 80: 325–332
   PubMed Web of Science ®Google Scholar
• Ault K A, Antin J H, Ginsburg D, Orkin S H, Rappeport J M, Keohan M L, et al. The phenotype of recovering lymphoid populations following marrow transplantation. J Exp Med 1985; 161: 1483–1502
   PubMed Web of Science ®Google Scholar
• Miller R A, Gralow J. The induction of leu-1 antigen expression in human malignant and normal B cells by phorbol myristate acetate. J Immunol 1984; 133: 3408–3414
   PubMed Web of Science ®Google Scholar
• Hollander N, Pillemer E, Weissman I L. Effects of lyt antibodies on T-cell functions: augmentation by anti-lyt-1 as opposed to inhibition by anti-lyt-2. Proc Natl Acad Sci USA 1981; 78: 1148–1151
   Google Scholar
• Logdberg L, Shevach E M. Role of the ly-1 antigen in interleukin 1-induced thymocyte activation. Eur J Immunol 1985; 15: 1007–1013
   Google Scholar
• Stanton T, Stevens T L, Ledbetter J A, Wofsky D. Anti-ly-1 antibody induces interleukin 2 release from T cells. J Immunol 1986; 136: 1734–1737
   Google Scholar
• Ledbetter J A, Martin P J, Spooner C E, Wofsky D, Tsu T T, Beatty P G, Gladstone P. Antibodies to Tp67 and Tp44 augment and sustain proliferative responses of activated T cells. J Immunol 1985; 135: 2331–2336
   PubMed Web of Science ®Google Scholar
• Walker C, Bettens F, Pichler W J. Activation of T cells by cross-linking an anti-CD3 antibody with a second anti-T cell antibody: mechanism and subset-specific activation. Eur J Immunol 1987; 17: 873–880
   Google Scholar
• Thomas Y, Glickman E, DeMartino J, Wang J, Goldstein H, Chess L. Biologic functions of the OKT1 T cell surface antigen. I. The T1 molecule is involed in helper function. J Immunol 1984; 133: 724–728
   PubMedGoogle Scholar
• Ovnic M, Corley R B. Quantitation of cell surface molecules on a differentiating ly-1+ B lymphoma. J Immunol 1987; 138: 3075–3082
   PubMedGoogle Scholar
• June C H, Rabinovitch P S, Ledbetter J A. CDS antibodies increase intracellular ionized calcium concentration in T cells. J Immunol 1987; 138: 2788–2792
   Google Scholar
• Greiner D L, Goldschneider I, Komschlies K L, Medlock E S, Bollum F J, Schultz L. Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (m/m) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells. J Exp Med 1986; 164: 1129–1144
   PubMed Web of Science ®Google Scholar
• Steele E J, Cunningham A J. High proportion of immunoglobulin-producing cells making autoantibody in normal mice. Nature 1978; 274: 493–484
   Google Scholar
• Pages J, Bussard A G. Precomittment of normal mouse peritoneal cells by erythrocyte antigens in relation to autoantibody production. Nature (Lond) 1975; 263: 60–61
   Google Scholar
• Dighiero G, Lymberi P, Holmberg D, Lundquist I, Couthino A, Avrameus S. High frequency of natural autoantibodies in normal newborn mice. J Immunol 1985; 134: 765–771
   PubMed Web of Science ®Google Scholar
• Holmberg D, Forsgren S, Ivars F, Coutinho A. Reactions among IgM antibodies derived from neonatal mice. Eur J Immunol 1984; 14: 435–441
   PubMed Web of Science ®Google Scholar
• Plater-Zyberk C, Maini R N, Lam K, Kennedy T D, Janossy G. A rheumatoid arthritis B cell subset expresses a phenotype similar to that in chronic lymphocytic leukaemia. Arthritis and Rheumatism 1985; 86: 971–976
   Google Scholar
• Perlmutter R M, Kearney J F, Chang S P, Hood L E. Developmentally controlled expression of immunoglobulin VH genes. Science 1985; 227: 1597–1601
   PubMed Web of Science ®Google Scholar
• Holmberg D, Freitas A A, Portnoi D, Jacquemart F, Avrameas S, Coutinho A. Antibody repertoires of normal BALB/c mice: lymphocyte populations denned by state of activation. Immunological Reviews 1986; 93: 147–169
   PubMedGoogle Scholar
• Yancopoulos G D, Desiderio S V, Paskind M, Kearney J F, Baltimore D, Alt F W. Preferential utilisation of the most JH-proximal VHgene segments in pre-B cell lines. Nature 1984; 311: 727–733
   PubMed Web of Science ®Google Scholar
• Alt F W, Blackwell T K, DePinho R A, Reth M G, Yancopoulos G D. Regulation of genome rearrangement events during lymphocyte differentiation. Immunological Reviews 1986; 89: 5–30
   PubMed Web of Science ®Google Scholar
• Wu G E, Paige C J. VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay. EMBO J 1986; 5: 3475–3481
   PubMed Web of Science ®Google Scholar
• Monestier M, Manheimer-Lory A, Bellon B, Painter C, Dang H, Talal N., et al. Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterise murine autoantibodies of various specificities. J Clin Invest 1986; 78: 753–759
   PubMed Web of Science ®Google Scholar
• Painter C, Monestier M, Bonin B, Bona C. Functional and molecular studies of V genes expressed in autoantibodies. Immunological Reviews 1986; 94: 75–98
   PubMed Web of Science ®Google Scholar
• Shlomchik M, Nemazee D, Van Snick J, Weigert M. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunisation. J Exp Med 1987; 165: 970–987
   PubMed Web of Science ®Google Scholar
• Conger J D, Pike B L, Nossal G JV. Clonal analysis of the anti-DNA repertoire of murine B lymphocytes. Proc Natl Acad Sci USA 1987; 84: 2931–2935
   PubMed Web of Science ®Google Scholar
• Ropes M W, Bennett G A, Caleb S, Jacox R, Jessar R A. Revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis 1958; 9: 175–176
   PubMedGoogle Scholar