15
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Perturbation of the Autoimmune Network. I. Immunization with Anti-Idiotypic Antibodies Prior to Challenge with Antigen Induces Quantitative Variations in the Autoantibody Response

, &
Pages 23-36 | Published online: 07 Jul 2009

References

  • Hart D A, Wang A L, Pawlak L L, Nisonoff A. Suppression of idiotypic specificities in adult mice by administration of anti-idiotypic antibody. J Exp Med 1972; 135: 1293
  • Reth M, Kelsoe G, Rajewsky K. Idiotypic regulation by isologous monoclonal anti-idiotope antibodies. Nature 1981; 290: 259
  • Forni L, Coutinho A, Kohler G, Jerne N K. IgM antibodies induce the production of antibodies of the same specificity. Proc Natl Acad Sci (USA) 1980; 77: 1125
  • Bona C, Hooghe R, Cazenave P A, Leguern C, Paul W E. Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies bearing 460 idiotypes. J Exp Med 1979; 149: 815
  • Bona C A, Herber-Katz E, Paul W E. Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones. J Exp Med 1981; 153: 951
  • Urbain J, Wikler M, Franssen J D, Collignon C. Idiotypic regulation of the immune system by the induction of antibodies against anti-idiotypic antibodies. Proc Natl Acad Sci USA 1977; 74: 5126
  • Bluestone J A, Sharrow S O, Epstein S L, Ozato K, Sachs D H. Induction of anti-H-2 antibodies without allo-antigen exposure by in vivo administration of anti-idiotype. Nature 1981; 291: 233
  • Jerne N K. Towards a network theory of the immune system. Ann Immunol (Paris) 1974; 125: 373
  • Zanetti M. Anti-idiotypic antibodies and autoantibodies. Ann NY Acad Sci 1983; 418: 363
  • Zanetti M. The idiotype network in autoimmune processes. Immunol Today 1985; 6: 299
  • Zanetti M, Rogers J, Katz D H. Regulation of the Immune System, E Sercarz Cantor, H. L Chess. Alan R Liss Pub, New York 1984; Vol 18: 893
  • Zanetti M, De Baets M, Rogers J. High degree of idiotypic cross-reactivity among murine monoclonal antibodies to thyroglobulin. J Immunol 1983; 131: 2452
  • Liu F-T, Bohn J W, Ferry E L, Yamamoto H, Molinaro C A, Sherman L A, Klinman N R, Katz D H. Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization. J. Immunol 1980; 124: 2728
  • Zanetti M, Liu F-T, Rogers J, Katz D H. Heavy and light chains of a mouse monoclonal autoantibody express the same idiotype. J Immunol 1985; 135: 1245
  • Zanetti M, Rogers J, Katz D H. Induction of autoantibodies to thyroglobulin by anti-idiotypic antibodies. J Immunol 1984; 133: 240
  • McConahey P J, Dixon F J. A method of trace iodination of proteins for immunological studies. Int Arch Allergy Appl Immunol 1966; 29: 185
  • Harper J R, Orengo A. The preparation of an immunoglobulin-amyloglucosidase conjugate and its quantitation by an enzyme-cycling assay. Anal Biochem 1981; 113: 51
  • Eichmann K. Idiotype suppression. I. Influence of the dose and of the effector functions of anti-idiotypic antibody on the production of an idiotype. Eur J Immunol 1974; 4: 296
  • Kluskens L, Kohler H. Regulation of immune response by autogeneous antibody against receptor. Proc Natl Acad Sci (Wash) 1974; 71: 5083
  • Bona C, Lieberman R, House S, Green I, Paul W E. Immune response to levan. II. T independence of suppression of cross-reactive idiotype by anti-idiotype antibodies. J Immunol 1979; 122: 1614
  • Brown C A, Carey K, Colvin R B. Inhibition of auto-immune tubulointerstitial nephritis in guinea pigs by heterologous antisera containing anti-idiotype antibodies. J Immunol 1979; 123: 2102
  • Zanetti M, Mampaso F, Wilson C B. Anti-idiotype as a probe in the analysis of autoimmune tubulointerstitial nephritis in the Brown Norway rat. J Immunol 1983; 131: 1268
  • Hahn B H, Ebling F M. Suppression of murine lupus nephritis by administration of an anti-idiotypic antibody to anti-DNA. J Immunol 1984; 132: 187
  • Zanetti M, Bigazzi P E. Anti-idiotypic immunity and auto-immunity. I. In vitro and in vivo effects of anti-idiotypic antibodies to spontaneously occurring autoantibodies to rat thyroglobulin. Eur J Immunol 1981; 11: 187
  • Zanetti M, Katz D H. Current Topics in Microbiology and Immunology, H Koprowski, F Melchers. Springer-Verlag Pub, Heidelberg 1985; Vol 119: 111
  • Zanetti M, Glotz D, Rogers J. Perturbation of the autoimmune network. II. Immunization with isologous idiotype induces auto-anti-idiotypic antibodies and suppresses the autoantibody response elicited by antigen. A serologic and cellular analysis. J Immunol 1986; 137: 3140
  • Male D, Pryce G, Quartey-Papafio R, Roitt I. The occurrence of defined idiotypes on autoantibodies to mouse thyroglobulin. Eur J Immunol 1983; 13: 942
  • Pene J, Bekkhoucha F, Desaymard C, Zaghouani H, Stanislawski M. Induction of a cross-reactive idiotype dextran-positive antibody response in two Igh-Cb mouse strains treated with anti-J558 cross-reactive idiotype antibodies. J Exp Med 1983; 157: 1573
  • Kennedy R C, Adler-Storthz K, Henkel R D, Sanchez Y, Melnick J L, Dreesman G R. Immune response to hepatitis B surface antigen: enhancement by prior injection of antibodies to the idiotype. Science 1983; 221: 853
  • Miller G G, Nadler P I, Asano Y, Hodes R J, Sachs D H. Induction of idiotype-bearing nuclease-specific helper T cells by in vivo treatment with anti-idiotype. J Exp Med 1981; 154: 24
  • Gleason K, Pierce S, Kohler H. Generation of idiotype-specific T cell help through network perturbation. J Exp Med 1981; 153: 924

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.