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Original Article

Aids and Autoimmunity : For Debate

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Pages 201-212 | Received 10 Jun 1988, Accepted 03 Nov 1988, Published online: 07 Jul 2009

References

  • Gallo R C, Sarin P S, Ep Gelman, Robert-Guroff M, Richardson E, Kalyanaram V S, Mann D, Sidhu G D, Stahl R E, Zolla-Pazner S, Leibowitch J, Popovic M. Isolation of human T cell leukemia virus in AIDS. Science 1983; 220: 865–867
  • Gallo R C, Sz Salahuddin, Popovic M, Shearer G M, Kaplan M, Haynes B F, Palker T J, Redfield R, Oleaske J, Safai B, White G, Foster P, Markham P D. Frequent detection and isolation of cytopathic retroviruses for AIDS. Science 1984; 224: 500–502
  • Lane HC, Masui H, Edgar L C, Whalen G, Rook A H, Fauci A S. Abnormalities of B-cell activation and immunoregulation in patients with the aquired immunodeficiency syndrome. N Engl J Med 1983; 309: 453–458
  • Ziegler J L, Stites D P. Hypothesis; AIDS is an autoimmune disease directed at the immune system and triggered by a lymphotropic retrovirus. Clin Immunol Immunopathol 1986; 41: 305–313
  • Barre-Sinoussi F, Chermann J C, Rey F, Nugeyre M T, Chamaret S, Gruest J, Daguet C, Axler-Blin C, Vezinet-Brun F, Rouzioux C, Rosenbaum W, Montagnier L. Isolation of a T-lymphocytic retrovirus from a patient at risk for aquired immune deficiency syndrome (AIDS). Science 1983; 220: 868–871
  • Popovic M, Sarngadharan M G, Read E, Gallo R C. Detection, isolation, and continuous production of cytopathic retroviruses (HTCV-III) from patients with AIDS and pre-AIDS. Science 1984; 224: 497–500
  • Levy J A, Hoffman A D, Kramer S M, Landis J A, Shimabukuro J M, Oshiro L S. Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS. Science 1984; 225: 840–842
  • Inglehart J K. Health policy report: Financing the struggle against AIDS. N Engl J Med 1987; 317: 180–184
  • Gottlieb M S, Schroff R, Schanker H M, Weisman J D, Fan P T, Wolf R A, Saxon A. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexuals: evidence of a new aquired cellular immunodeficiency. N Engl J Med 1981; 305: 1425–31
  • Centers for Disease Control. Kaposi's sarcoma and Pneumocystis pneumonia among homosexual men—New York City and California. Morbid Mortal Weekly Rep 1981; 30: 305–8
  • Kopelman R, Zolla-Pazner S. Association of human immunodeficiency virus infection and autoimmune phenomena. Am J Med 1988; 84: 82–88
  • Spivak J L, Bender B S, Quinn T C. Hematologic abnormalities in the acquired immune deficiency syndrome. Am J Med 1984; 77: 224–228
  • Gupta S, Licorish K. The Coombs test and the acquired immunodeficiency syndrome (letter). Ann Intern Med 1984; 100: 462
  • Murphy M F, Metcalfe P, Waters A H, Linch D C, Cheigsong-Popov R, Carne C, Weller I VD. Immune neutropenia in homosexual men (letter). Lancet 1985; 1: 218–8
  • Morris L, Distenfield A, Amorosi E, Karpatkin S. Autoimmune thrombocytopenic purpura in homosexual men. Ann Intern Med 1982; 96: 714–717
  • Walsh C M, Nardi M A, Karpatkin S. On the mechanism of thrombocytopenia purpura in sexually active homosexual men. N Engl J Med 1984; 311: 635–39
  • Strieker R B, Abrams D I, Corash L C, Shuman M A. Target platelet antigen in homosexual men with immune thrombocytopenia. N Engl J Med 1985; 313: 1375–80
  • Williams RC, Jr., Masur H, Spira T J. Lymphocyte reactive aantibodies in acquired immune deficiency syndrome. J Clin Immunol 1984; 4: 118–123
  • Kloster B E, Tomar R H, Spira T. Lymphocytotoxic antibodies in the acquired immune deficiency syndrome (AIDS). Clin Immunopathol 1984; 30: 330–335
  • Dorsett B, Cronin W, Chuma V, Ioachim H L. Antilymphocyte antibodies in patients with the acquired immune deficiency syndrome. Am J Med 1985; 78: 621–626
  • Terasaki P I, Mottironi V D, Barnett E V. Cytotoxins in disease: autocytotoxins in lupus. N Engl J Med 1970; 283: 724–728
  • Winfield J B, Winchester R J, Kunkel H G. Association of cold reactive antilymphocyte antibodies with lymphopenia in systemic lupus erythmatosus. Arth Rheum 1975; 18: 587–594
  • Messner P R, Kennedy M S, Jelinek J G. Antilymphocyte antibodies in systemic lupus erythmatosus. Arth Rheum 1975; 18: 201–206
  • Ozturk G E, Kohler P F, Horsburgh CR, Jr., Kirkpatrick C H. The significance of antilymphocyte antibodies in patients with acquired immune deficiency syndrome (AIDS) and their sexual partners. J Clin Immunol 1987; 7: 130–139
  • Zolla-Pazner S. Serology. Basics on AIDS: A guide to clinician's laboratory studies in AIDS, M Melbye, P Ebbesen, RJ Biggar. Munksgard, Copenhagen 1984; 151–172
  • Seligmann M, Chess L, Fahey J L, Fauci A S, Lachmann P J, L'Age-Stehr J, Ngu J, Pinching A J, Rosen F S, Spira T J. AIDS—an immunologic reevaluation. N EnglJ Med 1984; 311(20)1286–1292
  • Nies K M, Louie J S. Impaired immunoglobulin synthesis by peripheral blood lymphocytes in systemic lupus erythmatosus. Arthritis Rheum 1978; 21(1)51–57
  • Ginsburg W W, Finkelman F D, Lipsky PE. Circulating and pokeweed mitogen-induced immunog-lobulin-secreting cells in systemic lupus erythmatosus. Clin Exp Immunol 1979; 35(1)76–88
  • Delfraissy J F, Segond P, Gelanaud P, Wallon C, Massias P, Dormont J. Depressed primary in vitro antibody response in untreated systemic lupus erythematosus. T helper cell defect and lack of defective suppressor cell function. J Clin Invest 1980; 66(1)141–148
  • Pelton B K, Denman A M. Defective B cell function in systemic lupus erythmatosus. Clin Exp Immunol 1982; 48(3)513–518
  • Euler H H, Kern P, Loffler H, Dietrich M. Precipitable immune complexes in healthy homosexual men: acquired immune deficiency syndrome and the related lymphadenopathy syndrome. Clin Exp Immunol 1985; 59: 267–275
  • McDougal I S, Hubbard M, Nichelson J K. Immune complexes in the acquired immunodeficiency syndrome (AIDS): relationship to disease manifestation, risk group and immunologic defect. J Clin Immunol 1985; 5: 130–138
  • Lightfoot M M, Folks T M, Redfield R, Gold J, Sell K W. Circulating IgA immune complexes in aids. Immunol Invest 1985; 14: 341–345
  • Toy P TCY, Reid M E, Burns M. Positive direct antiglobulin test associated with hyperglobulinemia in acquired immunodeficiency syndrome (AIDS). Am M Hematol 1985; 19: 145–150
  • Virgin H W, Unanue E. Immune complexes suppress cellular immunity. Ann NY Acad Sci 1984; 437: 16–27
  • Ras G J, Ejtychis H A, Anderson R, Van der Walt I. Mononuclear and polymorponuclear leukocyte dysfunction in male homosexuals with the acquired immunodeficiency syndrome (AIDS). S. Afr Med J 1984; 66: 806–809
  • Gottlieb M S, Groopman J E, Weinstein W H, Fahey J L, Detels R. The acquired Immunodeficiency Syndrome (UCLA Conference). Ann Int Med 1983; 99: 208–220
  • Smith H R, Steinburg A D. Autoimmunity—a perspective. Ann Rev Immunol, WE Paul, 1983; 1: 175
  • Cassono J J, Cohen A S. Malignancy in a series of 70 patients with systemic lupus erythematosus. Arthritis Rheum 1974; 17: 383
  • Staples P J, Gerding D N, Decker J L, Gordon RS, Jr. Incidence of infection is systemic lupus erythematosus. Arthritis Rheum 1974; 17: 1–10
  • Fauci A S. Immunologic abnormalities in the acquired immunodeficiency syndrome (AIDS). Clin Res 1984; 32(5)491–499
  • Schroff R W, Gottlieb M S, Prince H E, Chai L L, Fahey J L. Immunological studies of homosexual men with immunodeficiency and Kaposi's sarcoma. Clin Immunol Immunopathol 1983; 27(3)300–314
  • Nicholson J KA, McDougal J S, Spira T J, Cross G D, Jones B M, Reinherz E L. Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy. J Clin Invest 1984; 73(1)191–201
  • Bakke A C, Kirkland P A, Kitridou R C, Quismorio FP, Jr., Rea T, Ehresmann G R, Horwiwtz D A. T lymphocyte subsets in systemic lupus erythematosus. Correlations with corticosteroid therapy and disease activity. Arthritis Rheum 1983; 26: 745–750
  • Smith H R, Steinberg A D. Autoimmunity—a perspective. Ann Rev Immunol, WE Paul, 1983; 1: 175
  • Rook A H, Masur H, Lane H C, Frederick W, Kashara T, Macher A M, Djeu J Y, Manischewitz J F, Jackson L, Fauci A S, Quinnan GV, Jr. Interleukin-2 enhances the depressed natural killer and cytotoxic activities of lymphocytes form patients with the acquired immunodeficiency syndrome. J Clin Invest 1983; 72: 398–403
  • Tsokos G C, Rook A H, Djeu J Y, Balow J E. Natural killer cells and interferon responses in patients with systemic lupus erythematosus. Clin Exp Immunol 1982; 50: 239–245
  • Schattner A, Duggan D B. Natural killer cells—toward clinical application. Am J Hematol 1985; 18: 435–443
  • DeStefanou E, Friedman R M, Friedman-Kien A E, Goedert J J, Henriksen D, Preble O T, Sonnabend J A, Vilcek J. Acidlabile human leukocyte interferon in homosexual men with Kaposi's sarcome amd lymphadenopathy. J Inf Dis 1982; 146(4)451–459
  • Eyster M E, Goedert J J, Poon M C, Preble O T. Acid-labile alpha interferon. A possible preclinical marker for the acquired immunodeficiency syndrome in haemophilia. N Engl J Med 1983; 309(10)583–586
  • Preble O T, Eyster E M, Godert J J. Acid-labile alpha interferon (letter). N Eng J Med 1984; 310: 923
  • Preble O T, Black R J, Friedman R M, Klippel J H, Vilcek J. Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 1982; 216: 429–431
  • Hooks J J, Jordan G W, Cupps T, Moutsopoulos H M, Fauci A S, Notkins A L. Multiple interferons in the circulation of patients with systemic lupus erythematosus and vasculitis. Arthritis Rheum 1982; 25(4)396–400
  • Arvin A M, Miller J J. Acid labile alpha-interferon in the sera and synovial fluids from patients with juvenile arthritis. Arthritis Rheum 1985; 27: 582–585
  • Zolla-Pazner S, William D, El Sadr E. Quantitation of beta 2-microglobulin and other immune characteristics in a prospective study of men at risk for the acquired immunodeficiency syndrome. JAMA 1984; 251(22)2951–2955
  • Evrin P E, Strom T. Beta 2-microglobulin and its binding activity in serum from patients with SLE. Ann Rheum Dis 1984; 42(2)267–274
  • Sonnefield G. Modulation of immunity by interferon. Lymphokine Reports, E Pick. Academic Press, New York 1980; Vol 1: 113
  • Schattner A. Retroviruses, AIDS and SLE. Harefuah 1985; 251–253
  • Matsiota P, Chamaret S, Montagnier L, Avrameas S. Detection of natural autoantibodies in the serum of anti-HIV-positive individuals. Ann Inst Pasteur Immunol 1987; 138(2)223–233
  • Olsen R G, Tarr M J, Mathes L E, Whisler R, Du Plessis D, Schuiz E J, Blakeslee J R. Serological and virological evidence of human T-lymphotropic virus in systemic lupus erythematosus. Med Microbiol Immunol 1987; 176(2)53–64
  • Casali P, Rice G P, Oldstone M B. Viruses disrupt functions of human lymphocytes. Effects of measles virus and influenza virus on lymphocyte-mediated killing and antibody production. J Exp Med 1984; 159(5)1322–1337
  • Schwartz R S. Epstein-Barr virus—oncogen or mitogen? (editorial). N. Engl J Med 1980; 302(23)1307–1308
  • Shoenfield Y, Schwartz R S. Immunologic and genetic factors in autoimmune diseases. N Engl J Med 1984; 311(16)1019–1029
  • Schwartz B D, Schreffler D C. Genetic influences in the immune response. Clinical Immunology, CW Parker. WB Saunders, Philadelphia 1980; 49–85
  • Roubinian J R, Papoian R, Talal N. Androgenic hormones modulate autoantibody responses and improve survival in murine lupus. J Clin Invest 1977; 59(6)1066–1070
  • Shoenfield Y, Cohen I R. Infection and Autoimmunity. The Antigens, M. Sela. Academic Press, NY 1987; 307–330
  • Black P H, Levy E M. The human T-cell leukemia virus and AIDS (correspondence). N Engl J Med 1983; 309(14)856
  • Fauci A S. The syndrome of Kaposi's sarcoma and opportunisitic infections: an epidemiologically restricted disorder of immunoregulation. Ann Intern Med 1982; 96: 777–779
  • Nicholson J KA, McDougal J S, Spira T J, Cross G D, Jones B M, Reinherz E L. Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy. J Clin Invest 1984; 73: 191–201
  • Theofiloporilos A N, Dixon F J. Autoimmune diseases: immunopathy and etiopathogenesis. Amer J Pathol 1982; 108: 319–365
  • Plotz P H. Autoantibodies are anti-idiotype antibodies to antiviral antibodies. Lancet 1983; 2: 824–826
  • Gleichmann E, Gleichmann H. G-I-G. Pathogenesis of graft-versus-host reactions (GVHR) and GVH-like diseases. J Invest Dermatol 1985; 85: 115–120, 1 suppl
  • Moser M, Iwasaki T, Shearer G M. Cellular interactions in graft-versus-host induced T cell immune deficiency. Immunol Rev 1985; 88: 135–51
  • Talal L, Shearer G. A clinician and a scientist look at acquired immunodeficiency syndrome (AIDS). Immunol Today 1983; 4(7)180–184
  • Friedman-Kien A, Lanbenstein L J, Rubinstein P. Ann Intern Med 1981; 96: 693–700
  • Salinger A M, Adams L E, Friedman-Klein A E, Hess E V. Acquired Immune Deficiency, Syndrome (AIDS) and autoimmunity—mutually exclusive entities. J Clin Immunol 1988; 8(1)32–42
  • Johnson R T, Richardson E P. The neurological manifestations of systemic lupus erythematosus. Medicine (Baltimore) 1968; 47: 337–365
  • Snider W D, Simpson D M, Nielson S, Gold J WM, Metroka C E, Posner J B. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 1983; 14: 403–418
  • Gardenswartz M H, Lerner C W, Seligson G R. Renal disease in patients with AIDS: a clinicopathologic study. Clin Nephrol 1984; 21: 197–204
  • Pardo V, Aldana M, Colton RM. Glomerular lesions in the acquired immunodeficiency syndrome. Ann Intern Med 1984; 101: 423–434
  • Rao T KS, Filippone E J, Nicastri A D. Associated focal and segmental glomerulosclerosis in the acquired immunodeficiency syndrome. N Engl J Med 1984; 310: 669–673
  • Eisenstat B, Wormser G. Seborrheic dermatitis and butterfly rash in AIDS (letter). N Engl J Med 1984; 311: 189
  • Levy R M, Bredesen D E, Rosenblum M L. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg 1985; 62: 475–495
  • Piette A M, Tusseau F, Vignon D. Acute neuropathy coincident with scioconversion for anti-LAV/HTLV III (letter). Lancet 1986; 1: 852
  • Dalakas M C, Pezeshkpour G H, Gravell M, Sever J L. Polymyositis associated with AIDS retrovirus. JAMA 1986; 256: 2381–2383
  • HO DD, Rota T R, Schooley R T. Isolation of HTLV III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med 1984; 313: 1493–1497
  • Liplin W I, Parry G, Kiprov D, Abrams D. Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology 1985; 35: 1479–1483
  • Kiprov D D, Lippert R, Miller R G. The use of plasmapheresis, lymphocytopheresis and staph protein—A immunoabsorption as an immunomodulatory therapy in patients with AIDS and AIDS-related conditions. J Clin Apheresis 1986; 3: 133–139
  • Kiprov D D, Lippert R, Sandstrom E. Acquired immunodeficiency syndrome (AIDS) -apheresis and operative risks. J Clin Apheresis 1985; 2: 427–440
  • Koffler D, Scherr P H, Kunkel H G. Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med 1967; 126: 607–624
  • Mathes B M, Douglass M C. Seborrheic dermatitis in patients with acquired immunodeficiency syndrome. J Am Acad Dermatol 1985; 13: 947–951
  • Saeprono F F, Schinella R A, Cockerell C J, Comite S L. Seborrheic-like dermatitis of acquired immunodeficiency syndrome. J Am Acad Dermatol (part 1) 1986; 14: 242–248
  • Donahue R E, Johnson M M, Zon L I, Clark S C, Groopman J E. Suppression of in vitro hematopoies-is following human immunodeficiency virus infection. Nature 1987; 326: 200–203
  • Siegel J P, Djer J Y, Stocks N I, Masur H, Gleman E P, Quinnan GV, Jr. Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes. J Clin Invest 1985; 75: 1957–1964
  • Terwillinger E, Sodroski J G, Rosen C A, Haseltine W A. Effects of mutations within the 3 orf region of human T-cell lymphotropic virus III on replication and cytopathogenicity. J Virol 1986; 60: 754–760
  • Zagury P, Bernard J, Leonard R. Long-term cultures of HTLV-III infected T cells. A model of cytopathology of T cell depletion of AIDS. Science 1986; 231: 850–853
  • Schreiber Z A, Loh S H, Charles M, Abeebe L S. Autoimmune hemolytic anemia in patients with the acquired immune deficiency syndrome (AIDS) (abstr). Blood 1983; 92: 117 A, suppl 1
  • Calabrese L H, Proffitt M R, Segal A M, Starkey C, Britz V A, Munton F. Clinical significance of serologic reactivity to human T cell lymphotropic virus type III (HTLV III) in patients with autoimmune disease (abstr). Arthritis Rheum 1986; 29: S21
  • Naher H, Tilgen W, Tilz G, Petzoldt D. False-positive results in the detection of anti-LAV/HTLV III antibodies by enzyme immunoassay. Hautarzt 1986; 37: 338–340
  • Winchester R, Bernstein D H, Fischer H D. The cooccurrence of Reiter's syndrome and acquired immunodeficiency. Ann Intern Med 1987; 706: 19–26
  • Bermann A, Espimosa L R, Diaz J D, Aguilar J L, Rolando T, Vasey F B, German B F, Lockey R F. Rheumatic manifestations of human immunodeficiency virus infection. Amer J Med 1988; 85: 59–64

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