Multiple Sclerosis: Cell-Mediated Immunity to Human Brain Gangliosides

References

• Waksman B H, Reynolds W E. Multiple Sclerosis as a disease of immune regulation. Proc Soc Exp Biol Med 1984; 175: 282–294
   PubMed Web of Science ®Google Scholar
• Lisak R P, Behan P O, Zweiman B, Shetty T. Cell-mediated immunity to myelin basic protein in acute disseminated encephalomyelitis. Neurol 1974; 24: 560–564
   PubMedGoogle Scholar
• Sheremata W, Younge B, Eylar E H. Retrobulbar neuritis in vitro evidence of sensitization to myelin basic protein in patients without Multiple Sclerosis. Neurology 1977; 27: 557–560
   Google Scholar
• Cochran F B, Yu R K, Ledeen R W. Mylein gangliosides in vertebrates. J Neurochem 1982; 39: 773–779
   Google Scholar
• Kim S U, Moretto G, Lee V, Yu R K. Neuroimmunology of gangliosides in human neurons and glial cells in culture. J Neurosc Res 1986; 15: 301–321
   Google Scholar
• Arnon R, Crisp E, Kelley R, Ellison G W, Myers L W, Tourtellotte W. Anti-ganghoside antibodies in Multiple Sclerosis. J Neurol Sci 1980; 46: 179–186
   Google Scholar
• Offner H, Konat G, Sela B A. Multi-sialo brain gangliosides are powerful stimulators of active E rosetting lymphocytes from MS patients. J Neurol Sci 1981; 52: 279–287
   Google Scholar
• Sela B A, Offner H, Konat G, Lev-Ram V, Cohen O, Cohen I R. Immunological expression of gangliosides in Multiple Sclerosis and in a demyelinating model disease in rabbits. Adv Exp Med Biol 1984; 174: 441–453
   Google Scholar
• Offner H, Standage B A, Burger D R, Vandenbark A A. Delayed type hypersensitivity to gangliosides in the Lewis rats. J Neutroimmunol 1985; 9: 147–157
   Google Scholar
• Roth G A, Roytta M, Yu R K, Raine C S, Bornstein M B. Antisera to different glycolipids induce myelin alterations in mouse spinal cord tissue cultures. Brain Res 1985; 339: 9–18
   Google Scholar
• Ilyas A A, Davison A N. Cellular hypersensitivity to gangliosides and myelin basic protein in Multiple Sclerosis. J Neurol Sci 1983; 59: 85–95
   Google Scholar
• Robb R J. The suppressive effect of gangliosides upon IL2-dependent proliferation as a function of inhibition of 112-receptor association. J Immunol 1986; 136: 971–976
   PubMed Web of Science ®Google Scholar
• Bellamy A, Davison A N, Feldmann M. Derivation of ganglioside - specific T cell lines of suppressor or helper phenotype from cerebrospinal fluid of Multiple Sclerosis patients. J Neuroimmunol 1986; 12: 107–120
   Google Scholar
• Thor D E, Jureziz R E, Veach S R, Miller E, Dray S. Cell migration inhibition factor released by antigen from human peripheral lymphocytes. Nuture 1968; 219: 755–757
   Google Scholar
• Rocklin R E, Meyers O L, David J R. An in vitro assay for cellular hypersensitivity in man. J Immunol 1970; 104: 95–102
   PubMed Web of Science ®Google Scholar
• Rocklin R E. Products of activated lymphocytes: Leukocyte Inhibitory Factor (LIF) distinct from Migration Inhibitory Factor (MIF). J Immunol 1974; 112: 1461–1466
   PubMed Web of Science ®Google Scholar
• Behan P Q, Behan W MH, Feldman R G, Kies M W. Cell-mediated hypersensitivity to neural Antigens. Arch Neurol 1972; 27: 145–152
   PubMedGoogle Scholar
• McCoy J L, Braatz J A, Ames R S, Herberman R B. Production and characterization of supernatants with high titers of human leukocyte inhibitory factor (LIF). J Immunol 1980; 124: 2786–2793
   Google Scholar
• Topliss D, How J, Lewis M, Row V, Volpe R. Evidence for cell-mediated immunity and specific suppressor T lymphocyte dysfunction in Graves' disease and diabetes mellitus. J Clin Endocrinol Metab 1983; 57: 700–705
   PubMed Web of Science ®Google Scholar
• Van de Plassche-Boers E M, Dredhage H A, Kokjeklleingeld M, Leezenberg H A. Parameters of T cell mediated immunity to commensal microorganisms in patients with chronic purulent rhinosinusitis: a comparison between delayed type hypersensitivity skin test, lymphocyte transformation test and macrophage migration inhibition factor assay. Clin Exp Immunol 1986; 66: 516–524
   PubMed Web of Science ®Google Scholar
• McDonald W I, Halliday A M. diagnosis and classification of Multiple Sclerosis. Br Med Bull 1977; 33: 4–8
   PubMed Web of Science ®Google Scholar
• Söborg M, Bendixen G. Human lymphocyte migration as a parameter of hypersensitivity. Acta Med Scand 1967; 181: 247–256
   PubMedGoogle Scholar
• McGill R, Tukey J W, Larsen N. Variations on Box Plots. Am Stat 1978; 32: 12–15
   Web of Science ®Google Scholar
• Koopmans L H. the K-Sample Problem. An introduction to contemporary statistics, B Gracia, C Beal. Duxbury Press, Boston 1981; 350–354
   Google Scholar
• Frick E. Cell-mediated cytotoxicity by peripheral blood lymphocytes against basic protein of myelin, encephalitogenic peptide. cerebrosides and gangliosides in Multiple Sclerosis. J. Neurol Sci 1982; 57: 55–66
   Google Scholar
• Frick E. Optic Neuritis in Multiple Sclerosis. Cell-mediated cytotoxicity by peripheral blood lymphocytes against basic protein of myelin, encephalitogenic peptide, cerebrosides and gangliosides. Eur Neuro 1988; 28: 120–125
   Google Scholar
• Johnson D, Hafler D A, Quarles R H, Lees J. Cell-mediated immunity to myelin associated glycopro-tein, proteolipid protein and myelin basic protein in multiple sclerosis. J Neuro Immunol 1986; 13: 99–104
   PubMed Web of Science ®Google Scholar
• Knorr-Held S, Brendl W, Kiefer H, Paal G, Von Specth B U. Sensitization against brain gangliosides after therapeutic swine brain implantation in a Multiple Sclerosis patient. J Neurol 1986; 233: 54–56
   Google Scholar
• Van Heyningen W E. Gangliosides as membrane receptors for tetanus toxin, cholera toxin and serotonin. Nature 1974; 249: 415–417
   Web of Science ®Google Scholar
• Schwerer B, Lassman H, Kitz K, Berheimer H. Ganglioside GMI, a molecular target for immunological and toxic attacks: similarity of neuropathological lesions induced by ganglioside antiserum and cholera toxin. Acta Neuropathol 1986; 72: 55–61
   Google Scholar
• Hakomori S I. Ganglioside receptors: a brief overview and introductory remarks. Ganglioside structure function and biomedical potential, R W Ledeen, R K Uy, M M Rapport, K Suzuki. Plenum Press, New York 1984; 333–339
   Google Scholar
• Jahnkc U, Fischer E H, Alvord E C, Jr. Sequence homology between certain viral proteins and proteins related to Encephalomyelitis and Neuritis. Science 1985; 229: 282–284
   Google Scholar
• Clark R, Dore-Duffy P, Donaldson J, Pollard M K, Muirhead S. Generation of phenotypic helper/ inducer and suppressor/cytotoxic T cell lines from cerebrospinal fluid in Multiple Sclerosis. Cell Immunol 1984; 84: 409–414
   PubMed Web of Science ®Google Scholar
• Santoli D, Defreitas E C, Sandgerg-Wollheim M, Francis M K, Koprowski H. Phenotypic and functional characterization of T cell clones derived from the cerebrospinal fluid of Multiple Sclerosis patients. J Immunol 1984; 132: 2386–2392
   Google Scholar
• Hafler D A, Benjamin D S, Burks J, Weiner H L. Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfec-tious encephalomyelitis. J Immunol 1987; 139: 68–72
   PubMedGoogle Scholar
• Richert J R, McFarlin D E, Rose J W, McFarland H F, Greenstein J I. Expansion of antigen-specific T cells from cerebrospinal fluid of patients with Multiple Sclerosis. J Neurol 1983; 5: 317–324
   Google Scholar
• Weber W, Buurman W, Vandermeeren M, Medaer R, Raus J. Human T lymphocyte clones specific for myelin basic protein. abstract book. 6^th Internat. Congress of Immunology. National Research Council Canada, Ottawa 1986; 467
   Google Scholar
• Richert J R, Rose J W, Reubein-Burnside C, Kearns M C, Jacobson S, Mingioli E, Hartzman R J, McFarland H F, McFarlin D E. Polypeptide specificities of measles virus-reactive T cell lines and clones derived from a patient with Multiple Sclerosis. J Immuno 1986; 137: 2190–2194
   Google Scholar