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Autoimmunity Volume 7, 1990 - Issue 2-3
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Original Article

Induction of Diabetes in PVG/c Strain Rats by Manipulation of the Immune System

W. John Penhale Divisions of Veterinary Biology and Applied, Veterinary Medicine, Murdoch University, Murdoch, Western Australia, 6150
,
Philip A. Stumbles Divisions of Veterinary Biology and Applied, Veterinary Medicine, Murdoch University, Murdoch, Western Australia, 6150
,
Clive R. Huxtable Divisions of Veterinary Biology and Applied, Veterinary Medicine, Murdoch University, Murdoch, Western Australia, 6150
,
R. James Sutherlanld Divisions of Veterinary Biology and Applied, Veterinary Medicine, Murdoch University, Murdoch, Western Australia, 6150
&
David W. Pethick Divisions of Veterinary Biology and Applied, Veterinary Medicine, Murdoch University, Murdoch, Western Australia, 6150
Pages 169-179 | Received 11 Jan 1990, Accepted 26 Mar 1990, Published online: 07 Jul 2009

References

  • Like A A, Appel M C, Rossini A A. Autoantibodies in the BB/W rat. Diabetes 1982; 31: 816–820
  • Ndmp J, Lemmark M DM. Autoimmunity in insulin-dependent diabetes. Am. J. Med 1981; 70: 135–140
  • Boitard C, McDevitt H O. Immunology of insulin-dependent diabetes mellitus. Perspectives on Autoimmunity, I Cohen. CRC Press Inc., FloridaUSA 1988; 34–58
  • Penhale W J, Farmer A, McKenna R P, Irvine W J. Spontaneous thyroiditis in thymectomized and irradiated Wistar rats. Clin. exp. Immunol 1973; 15: 225–236
  • Penhale W J, Irvine W J, Inglis J MR, Farmer A. Thyroiditis in T cell depleted rats: Suppression of the autoallergic response by reconstitution with normal lymphoid cells. Clin. exp. Immunol 1976; 25: 6–16
  • Ahmed Ansar S, Penhale W J. Thyroid transplantation in rats developing autoimmune thyroiditis following thymectomy and irradiation. Clin. exp. Immunol 1981; 45: 480–486
  • Seemayer T A, Tannenbaum G S, Goldman H, Colle E. Animal model: Spontaneous diabetes mellitus in the BB Wistar rat. Am. J. Pathol 1980; 101: 485–488
  • Nishiyama R H, Torreui D B, Martin S, Belbez Pek S, Keren D F. The detection of islet-cell antibodies by immunofluorescence on Bouin's-fmed paraffim-embedded human pancreas. Lab. Invest 1980; 43(2)191–195
  • Williamson D H, Mellanby J, Krebs H A. Enzymic determination of D-3–hydroxybutync acid and aceto acetic acid in blood. Eiochem. J 1962; 82: 90–96
  • McGregor A M, Rennie D P, Weetman A P, Massman R A, Foord S M, Dieguez C, Hall R. The influence of cyclosporin A on experimental autoimmune thyroid disease in the rat. Life Sciences 1983; 32: 97–108
  • Penhale W J, Farmer A, Irvine W J. Thyroiditis in T-cell depleted rats: influence of strain, radiation dose, adjuvants and anti-lymphocyte serum. Clin. exp. Immunol 1975; 21: 362–375

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