Transfection of Genes for Cell Surface Products Involved in Antigen Presentation - Applications to the Understanding of Autoimunmity

References

• Germain R N, Malissen B. Analysis of the expression and function of class II major histocompatibility complex-encoded molecules by DNA-mediated gene transfer. Annu Rev Immunol 1986; 4: 281
   PubMed Web of Science ®Google Scholar
• Bjorkman P J, Saper M A, Samraoui B, Bennett W S, Strominger J L, Wiley D C. Structure of the human class I histocompatibility antigen, HLA-A2. Nafure 1987; 329: 506–512
   PubMed Web of Science ®Google Scholar
• Bjorkman P J, Saper M A, Samraoui B, Bennett W S, Strominger J L, Wiley D C. The foreign antigen binding site and T cell recognition regions of class I histocmpatibility antigens. Nature 1987; 329: 512–518
   PubMed Web of Science ®Google Scholar
• Brown J H, Jardetzky T, Saper M A, Samraoui B, Bjorkman P J, Wiley D C. A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules. Nature 1988; 332: 845–850
   PubMed Web of Science ®Google Scholar
• Marsh S G E, Bodmer J G. HLA-DR and -DQ epitopes and monoclonal antibody specificity. Immunol Today 1989; 10: 305–312
   PubMedGoogle Scholar
• Heyes J, Austin P, Bodmer J, Bodmer W F, Madrigal A, Mazzilli M C, Trowsdale J. Monoclonal antibodies to HLA-DP-transfected mouse L cells. Proc Nail Acad Sci USA 1986; 83: 3417–3421
   PubMedGoogle Scholar
• Klohe E P, Watts R, Bahl M, Alber C, Yu W -Y, Anderson R, et al. Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules. J Immunol 1988; 141: 2158–2164
   PubMedGoogle Scholar
• Kwok W W, Schwarz D, Nepom B S, Hock R A, Thurtle P S, Nepom G T. HLA-DQ molecules form aL-β heterodimers of mixed allotype. J Immunol 1988; 141: 3123–3127
   PubMed Web of Science ®Google Scholar
• Lotteau V, Sands J, Teyton L, Turmal P, Charron D, Strominger J L. Modulation of HLA class II antigen expression by transfection of sense and antisense DRu cDNA. J Exp Med 1989; 169: 351–356
   PubMedGoogle Scholar
• Wilkinson D, Altmann D M, Ikeda H, Trowsdale J. Analysis of HLA class II products by DNA mediated gene transfer. Molecular Biology OJ HLA class II antigens, J Silver, in press
   Google Scholar
• Ikeda H, Trowsdale J. Saito 1. Mulcos: a vector for amplification and simultaneous expression of two foreign genes in mammalian cells. Gene 1988; 71: 19–27
   PubMedGoogle Scholar
• Accolla R. Human B cell variants immunoselected against a single la antigen subset have lost expression of several la antigen subsets. J Exp Med 1983; 157: 1053
   PubMed Web of Science ®Google Scholar
• Austin P, Trowsdale J, Rudd C, Bodmer W F, Feldmann M, Lamb J. Functional expression of HLA-DP genes transfected into mouse fibroblats. Nature 1985; 313: 61–64
   PubMedGoogle Scholar
• Madrigal J A, Ikeda H, Marsh S G E, Heyes J M, Kennedy L J, Trowsdale J, Bodmer J G. J Immunol 1989; 143: 4084–4089
   PubMedGoogle Scholar
• Young J A T, Wilkinson D, Bodmer W F, Trowsdale J. Sequence and evolution of HLA-DR7– and DRw53–associated β chains. Proc Nail Acad Sci 1987; 84: 4929–4933
   PubMedGoogle Scholar
• Babbit B P, Allen P M, Matsueda G, Haber E, Unanue E. Binding of immunogenic peptides to Ia histocompatibility molecules. Nature 1985; 317: 359–361
   PubMed Web of Science ®Google Scholar
• Wraith D C, Smilek D E, Mitchell D J, Steinman L, McDevitt H O. Antigen recognition in autoimmune encephalomyelitis and potential for peptide-mediated immunotherapy. Cell 1989; 59: 247–255
   PubMed Web of Science ®Google Scholar
• Ceppelini R, Frumento G, Ferrara G B, Tosi R, Cherst A, Pernis B. Binding of labelled influenza matrix peptide to HLA-DR in living B lymphoid cells. Nature 1989; 339: 392–394
   PubMedGoogle Scholar
• Rothbard J B, Busch R, Howland K, Bal V, Fenton C, Taylor W R, Lamb, Jr. Structural analysis of peptide-HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor. Int Imrnunol 1989; 1: 479–486
   PubMedGoogle Scholar
• Janeway C A, Yagi J, Conrad P, Katz M, Jones B, Vroegop S, Buxser S. T cell responses to MIS and bacterial protein that mimics its behaviour. Immunol Rev 1989; 107: 61
   PubMed Web of Science ®Google Scholar
• Mollick J A, Cook R G, Rich R. Class II MHC molecules are specific receptors for staphyloccus A. Science 1989; 244: 817–819
   PubMed Web of Science ®Google Scholar
• Scholl P, Mourad W, Parsonnet J, Geha R, Chatila T. Toxic shock syndrome toxin I binds to major histocompatibility complex class II molecules. Proc Nar Acad Sci 1988; 86: 4210–4214
   Google Scholar
• Herrman T, Accolla R S, MacDonald H R. Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complexes class II isotypes. Eur J Immunol 1989; 19: 2171–2174
   PubMedGoogle Scholar
• Wilkinson D, De Vries R R P, Madrigal J A, Lock C B, Morgenstern J P, Trowsdale J, Altmann D M. Analysis of HLA-DR glycoproteins by DNA-mediated gene transfer. J Exp Med 1988; 167: 1442–1458
   PubMedGoogle Scholar
• Rees A J, Peters D K, Compston A S, Batchelor J R. Strong association between HLA DRw2 and antibody mediated Goodpasture's syndrome. Lancet 1978; I: 966–967
   Google Scholar
• Langdon N K, Welsh K, van Dam M, Vaughan M, Parkes J D. Genetic markers in narcolepsy. Lancet 1984; ii: 1178–1179
   Google Scholar
• Compston A. Genetic factors in the etiology of multiple sclerosis. Multiple Sclerosis, W McDonald, I HD Silberberg. Butterworths, London 1986; 56–73
   Google Scholar
• van Eden W, de Vries R RP, Mehra N K, Vaidya M C, D'Amaro J, van Rood J J. HLA segregation of tuberculoid leprosy: confirmation of the DR2 marker. J Infect Dis 1980; 141: 693–701
   PubMed Web of Science ®Google Scholar
• Lee B S M, Rust N A, McMichael A J, McDevitt H O. HLA-DR2 subtypes form an additional supertypic family of DRP alleles. Proc Nail Acad Sci USA 1987; 84: 4591–4595
   PubMedGoogle Scholar
• Bontrop R, Ottentoff T, van Miltenburg R, Elferink D, de Vries R, Giphart M. Quantitative and qualitative differences in HLA-DR molecules correlated with antigen presentation capacity. Eur J Immunol 1986; 16: 133–138
   PubMedGoogle Scholar
• Sekaly R P, Jacobson S, Richert J R, Tonnelle C, McFarland H F, Long E O. Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain. Proc Narl Acad Sci USA 1988; 85: 1209–1212
   PubMedGoogle Scholar
• Spits H, van Schoooten W, Keizer H, van Seveter G, van de Rijn M, Terhorst C, de Vries J E. Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells. Science 1986; 232: 403–405
   PubMed Web of Science ®Google Scholar
• Gougeon M -L, Bismuth G, Theze J. Differential effects of monoclonal antibodies anti-L3T4 and anti-LFAl on the antigen-induced proliferation of T-helper-cell clones: correlation between their susceptibility to inhibition and their affinity for antigen. Cell Immunol 1985; 95: 75–83
   PubMedGoogle Scholar
• Marlin S D, Springer T A. Purified intercellular adhesion molecule-1(ICAM-1) is a ligand for lymphocyte function-associated antigen I (LFA-I). Cell 1987; 51: 813–819
   PubMed Web of Science ®Google Scholar
• Simmons D, Makgoba M W, Seed B. ICAM, an adhesion ligand of LFA-I, is homologous to the neural cell adhesion NCAM. Nature 1988; 331: 624–627
   PubMed Web of Science ®Google Scholar
• Makgoba M W, Sanders M E, Luce G E G, Dustin M L, Springer T A, Clark E A, Mannoni P, Shaw S. ICAM-1 a ligand for LFA-l-dependent adhesion of B, t and myeloid cells. Nature 1988; 331: 86–88
   PubMed Web of Science ®Google Scholar
• Mazerolles F, Lumbroso C, Lecomte O, Le Deist F L, Fischer A. The role of lymphocyte function-associated antigen (LFA-I) in the adherence of T lymphocytes to B lymphyocytes. Eur J Immunol 1988; 18: 1229–1234
   PubMedGoogle Scholar
• Altmann D M, Hogg N, Trowsdale J, Wilkinson D. Cotransfection of ICAM-I and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells. Nature 1989; 338: 512–514
   PubMed Web of Science ®Google Scholar
• Bottavo G E, Todd I, Mirakian R, Belfiore A, Pujol Borrell. Organ specific autoimmunity: A 1986 overview. Immunol Rev 1986; 94: 137–169
   PubMedGoogle Scholar
• Markmann J, Lo D, Naji A, Palmiter R D, Brinster R L, Heber-Katz E. Antigen presenting function of class II MHC expressing pancreatic beta cells. Nature 1988; 336: 476–479
   PubMed Web of Science ®Google Scholar
• Bohme J, Haskins K, Stecha P, van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant. Science 1989; 244: 1179–1183
   PubMed Web of Science ®Google Scholar
• Mentzer S J, Rothlein R, Springer T A, Faller D V. Intercellular adhesion molecule-I (ICAM-I) is involved in the cytolytic T lymphocyte interaction with a human synovial cell line. J Cell Physiol 1988; 137: 173–178
   PubMed Web of Science ®Google Scholar
• Hale L P, Martin M E, McCollum D E, Nunley J A, Springer T A, Singer K H, Hanes B F. Immunohis-tologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial environment. Arthritis Rheum 1989; 32: 22–30
   PubMed Web of Science ®Google Scholar
• van Kooyk Y, van de Wiel-van Kemenade P, Weder P, Kuijpers T W, Figdor C G. Enhancement of LFA-l-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature 1989; 342: 811–813
   PubMed Web of Science ®Google Scholar
• Dustin M L, Springer T A. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-I. Nature 1989; 341: 619–624
   PubMed Web of Science ®Google Scholar