8
Views
12
CrossRef citations to date
0
Altmetric
Original Article

The Effect of Carbimazole Therapy on Interleukin 2, Interleukin 2 Receptors and Free Radicals

, , , , &
Pages 3-7 | Received 29 Sep 1989, Published online: 07 Jul 2009

References

  • Volpé R, Karlsson A, Jansson R, Dahlberg P A. Evidence that antithyroid drugs induce remissions in Graves' disease by modulating thyroid cellular activity. Clin Endocrinol 1986; 25: 453
  • Kendall Taylor P. Are antithyroid drugs immunosuppressive?. Br Med J 1984; 288: 509
  • Wenzel K W, Lente J R. Similar effects of thionamide drugs and perchlorate on thyroid stimulating immunoglobulins in Graves' disease. Evidence against an immunosuppressive action of thionamide drugs. J din Endocrinol Metab 1984; 58: 62
  • Ludgate M E, McGregor A M, Weetman A P, Ratanachaiyvong S, Lazarus J H, Hall R, Middleton G. Analysis of T cell subsets in Graves' disease; alterations associated with Carbi-mazole. Br Med J 1984; 288: 526
  • McGregor A M, Ibbertson H K, Rees Smith B, Hall R. Carbi-mazole and autoantibody synthesis in Hashimoto's thyroiditis. Br Med J 1980; 281: 968
  • Wilson R, McKillop J H, Pearson C, Burnett A K, Thomson J A. Differential immunosuppressive action of Carbimazole and Propylthiouracil. Clin Exp Immunol 1988; 73: 312
  • Totterman T H, Karlsson F A, Bengtsson M, Mendle-Harting I. Induction of circulating activated suppressor-like T cells by Methimazole therapy for Graves' disease. N Engl J Med 1987; 316: 15
  • Weetman A P. The effect of the antithyroid drug Methimazole on Interleukin 1 and Interleukin 2 levels in vitro. Clin Endocrinol 1986; 25: 133
  • Rubin L A, Kurman C C, Fritz M E, Biddison W E, Boutin B, Yarchoan R, Nelson D L. Soluble Interleukin 2 receptors are released from activated human lymphoid cells in vitro. J Immunol 1985; 135: 3172
  • Hoffeld J T, Metzger Z, Oppenheimer J J. Oxygen derived metabolites as suppressors of immune responses in vitro. Lymphokines. Academic Press, New York 1981; 2: 63
  • Wilson R, McKillop J H, Choppra M, Bradley H, Thomson J A. Free radicals and Graves': disease: the effects of therapy. Clin Endocrinol 1989; 30: 429
  • Weetman A P, Holt M E, Campbell A K, Hall R, McGregor A M. Methimazole and the generation of oxygen radicals by monocytes; potential role in immunosuppression. Br Med J 1984; 288: 518
  • Wilson R, McKillop J H, Choppra M, Thomson J A. The effect of antithyroid drugs on B and T cell activity in vitro. Clin Endocrinol 1988; 28: 389
  • Boyum A. Isolation of leucocytes from human blood. Scan J Clin Lab Invest (suppl) 1986; 97: 21
  • Wilson R, Fraser W D, McKillop J H, Smith J, O'Reilly D, St J, Thomson J A. The “in vitro” effects of Lithium on the immune system. Autoimmunity 1989, in press
  • Misra H P, Fridovich I. Superoxide dismutase, a photochemical augmentation assay. Archiv Biochem Biophys 1977; 181: 308
  • Ellman G L. Tissue sulphydryl groups. Archiv Biochem 1959; 82: 70
  • Mendes E E, Bioiano J M, Murphy L, Refering H G. Modification of a p-phenylenediamine oxidase method to permit cae-ruloplasmin determinations. Anal Lett 1977; 10: 197
  • Balazs C, Kiss E, Leovey A, Farid N R. The immunosuppressive effect of Methimazole on cell mediated immunity is mediated by its capacity to inhibit peroxidase and to scavenge free oxygen radicals. Clin Endocrinol 1986; 25: 7
  • Halliwell B. Lipid peroxidation, oxygen radicals and anti oxidant therapy. Lancet 1984; 1: 1396

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.