References
- Mandrup-Poulsen T. On the pathogenesis of insulin dependent diabetes mellitus. Dun Med Bull 1988; 35: 438–460
- Comens P G, Wolf B A, Unanue E R, Lacy P E, McDaniel M L. Interleukin-I is a potent modulator of insulin secretion from isolated rat islets of Langerhans. Diabetes 1987; 36: 963–970
- Spinas G A, Palmer J P, Mandrup-Poulsen T, Andersen H, Nielsen H, Nerup J. The bimodal effect of interleukin-I on rat pancreatic β-cells-stimulation followed by inhibition-depends upon dose, duration of exposure and ambient glucose concentration. Acta Endocrinol (Copenh) 1988; 118: 307–311
- Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen J H, Dinarello C A. Ultrastructural studies of time-course and cellular specificity of interleukin-I mediated islet cytotoxicity. Acta Path Microbiol Immunol Scand Sect C 1987; 95: 55–63
- Mandrup-Poulsen T, Bendtzen K, Dinarello C, Nerup J. Human tumor necrosis factor potentiates human interleukin-I mediated rat pancreatic β-cell cytotoxicity. J Immunol 1987; 139: 4077–4082
- Nerup J, Mandrup-Poulsen T, Melvig J, Helqvist S, Wogensen L, Egeberg J. Mechanisms of pancreatic beta-cell destruction in type I diabetes. Diaberes Care 1988; 11(suppl 1)16–23
- Palmer J, Helqvist S, Spinas G A, Mølvig J, Mandrup-Poulsen T, Andersen H U, Nerup J. The beta-cell-a moving target? Interaction between pancreatic beta-cell activity, IL-I concentration and IL-l exposure time on insulin secretion from isolated rat islets of Langerhans. Diaheres 1989; 38: 1211–1216
- Dinarello C A. Biology of interleukin-I. FASEB J 1988; 2: 108–115
- Wogensen L D, Kolb-Bachofen V, Christensen P, Dinarello C A, Mandrup-Poulsen T, Martin S, Nerup J. Functional and morphological effects of interleukin-18 on the perfused rat pancreas. Diaberologia 1990; 33: 15–23
- Wogensen L D, Mandrup-Poulsen T, Markholst H, Lernmark A, Holst J J, Dinarello C A, Nerup J. Interleukin-I potentiates glucose stimulated insulin release in the isolated perfused pancreas. Acta Endocrinol (Copenh) 1988; 117: 302–306
- Svenningsen A, Dyrberg T, Markholst H, Binder C, Lernmark A. Insulin release and pancreatic insulin is reduced in young prediabetic BB rats. Acra Endocrinol 1986; 112: 367–371
- Dalbege H, Bayne S, Christensen Heinies KR. Cloning and expression of an interleukin-1β precusor and its conversion to interleukin-Iβ. FEBS 1989; 246: 89–93
- del Rey A, Besedovsky H. Interleukin-I affects glucose homeostasis. Am J Physiol 1987; 253: R794–R798
- Zawalich W S, Zawalich K C. Interleukin-I (IL-I) is a potent modulator of insulin secretion. Am J Physiol 1989; 256: E19–E24
- Wang Y, Goodman M, Lumerman J, Sussman K E, Dahl R, Lafferty K J, Draznin B. In vivo administration of interleukin-I inhibits glucose-stimulated insulin release. Diaberes Research and Clinical Practice 1989; 7: 205–211
- Svenningsen A, Bonnevie-Nielsen V. Effects of fasting on 8-cell function, body fat, islet volume, and total pancreatic insulin content. Metabolism 1984; 33: 612–616
- Efendic S, Cerasi E, Luft R, Gladnikoff G. Potentiation of glucose-induced insulin release by glucose in the isolated pancreas of fed and fasted rats. Diabetes 1976; 25: 949–954
- Curry D L. Insulin content and insulinogenesis by the perfused rat pancreas: Effects of long term glucose stimulation. Endocrinology 1988; 118: 170–175
- Gelfand R A, Sherwin R S. Glucagon and starvation. Handbook of experimental pharmacology Vol 66; Glucagon II, P J Lefebvre. Springer Verlag, London, Heidelberg, New York 1983; 223–237
- Spinas G A, Mandrup-Poulsen T, Biek L, Bendtzen K, Dinarello C A, Nerup J. Low concentrations of interleukin-I stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans. Acra Endocrinol (Copenh) 1986; 113: 551–558
- Spinas G A, Hansen B S, Linde S, Kastern W, Mslvig J, Mandrup-Poulsen T, Dinarello C A, Nielsen J H, Nerup J. Interleukin-I dose-dependently affects the biosynthesis of (pro) insulin in isolated islets of Langerhans. Diaherologia 1987; 30: 474–480
- Martin S, Maruta K, Burkart V, Gillis S, Kolb H. IL-I and IFN increase vascular permeability. Immunology 1988; 64: 301–305
- Lisi P J, Chu C W, Koch G A, Endres S, Dinarello C A. Development and use of a radio-immunoassay for human Interleukin-1β. Lymphokine Research 1987; 6: 229–244