12
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Longitudinal Immunoblotting Variations of Auto-Antibody Reactivity of Patients with Systemic Lupus Erythematosus

, , &
Pages 23-31 | Received 16 Aug 1989, Accepted 12 Jan 1990, Published online: 07 Jul 2009

References

  • Tan E M, Chan E KL, Sullivan K F, Rubin R L. Antinuclear antibodies (ANA's): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity. Clin Immunol Immunopathol 1988; 41: 121–141
  • Swaak A JG, Aarden L A, Statius van eps L W, Feltkamp T EW. Anti-ds DNA and complement profiles as prognostic guides in systemic lupus erythematosus. Arthritis Rheum 1979; 22: 226–235
  • McCarty G, Rice J R, Bembe M L, Pisetsky D S. Independent expression of autoantibodies in systemic lupus erythematosus. J Rheumaiol 1982; 9: 691–695
  • Homma M, Mimori T, Takeda Y, Akama H, Yoshida T, Ogasawara T, et al. Autoantibodies to the Sm antigen: immunological approach to clinical aspects of systemic lupus erythematosus. J Rheumatol 1987; 14(suppl. 13)188–193
  • Van Venrooij W J. Autoantibodies against small nuclear ribonucleoprotein components. J Rheumarol 1987; 14(Suppl 13)78–82
  • Barada F A, Andres B S, Davis J S, Taylor R P. Antibodies to Sm in patients with systemic lupus erythematosus. Correlation of Sm antibody titers with disease activity and other laboratory parameters. Arthritis Rheum 1981; 24: 1236–1244
  • Borg E J ter, Horst G, Hummel E, Jaarsma D, Limburg P C, Kallenberg G GM. Sequential development of antibodies to specific Sm polypeptides in a patient with systemic lupus erythematosus: evidence for independent regulation of anti-double stranded DNA and anti-Sm antibody production. Arthritis Rheum 1988; 31: 1563–1567
  • Habets W J, De Rooij D J, Hoet M H, Van de Putte L B, Venrooij W J. Quantitation of anti-RNP and anti-Sm antibodies in MCTD and SLE patients by immunoblotting. Clin Exp Immunol 1985; 59: 457–466
  • Houtman P M, Kallenberg C GM, Limburg P C, Huitema M G, Van Rijwijk M H, et al. Quantitation of antibodies to ribonucleoprotein by ELISA: relation between antibody levels and disease activity in patients with connective tissue disease. Clin Exp Immunol 1985; 62: 696–704
  • Takeda Y, Wang G S, Wang R J, Anderson S K, Petterson I, Amaki S, et al. Enzyme linked immunosorbent assay using isolated (U) small nuclear ribonucleoprotein polypeptides as antigens to investigate the clinical significance of autoantibodies to these polypeptides. Clin Immunol Immunopathol 1989; 50: 213–230
  • Petterson I, Wang G, Smith E I, Wigzell H, Hedfors E, Horn J, et al. The use of immunoblotting and immunoprecipitation of (U) small nuclear ribonucleoproteins in the analysis of sera of patients with mixed connective tissue disease and systemic lupus erythematosus. A cross-sectional longitudinal study. Arthritis Rheum 1986; 29: 986–996
  • Fisher D E, Reeves W H, Wisniewolski R, Lahita R G, Chiorazzi N. Temporal shifts from Sm to ribonucleoprotein reactivity in systemic lupus erythematosus. Arthritis Rheum 1985; 28: 1348–1355
  • Tan E M, Cohen A S, Fries J F, Masi A T, McShane D J, Rothfield N F, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271–1277
  • Lightfoot R W, Hughes G RV. Significance of persisting serologic abnormalities in SLE. Arthritis Rheum 1976; 19: 837–843
  • Swaak A JG, Nossen J C, Bronsveld W, Van Rooyen A, Nieuwenhuys E J, Theuns L, et al. Systemic lupus erythematosus. I. Outcome and survival: Dutch experience with 110 patients studied prospec-tively. Ann Rheum Dis 1989; 48: 447–454
  • Jonsson H, Nived O, Sturfeld G. Outcome in systemic lupus erythematosus: a prospective study of patients from a defined population. Medicine 1989; 68: 141–150
  • Morrow W JW, Isenberg D A, Todd-Pokropek A, Parry H G, Snaith M L. Useful laboratory measurements in the management of systemic lupus erythematosus. Quart J Med 1982; 51: 125–138
  • Fritzler M J, Tan E M. Antinuclear antibodies and the connective tissue diseases. Laboratory diagnostic procedures in the rheumatic diseases, Third ed., A S Cohen. Grune and Stratton, New York 1985
  • Aarden L A, Groot E R, Feltkamp T EW. Immunology of DNA. III Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique. Ann NY Acad Sci 1975; 264: 505–515
  • Aeschlimann A, Meyer O, Bourgeois P, Haim T, Belmatoug N, Palazzo E, et al. Anti-Scl 70 antibodies detected by immunoblotting in progressive systemic sclerosis: specificity and clinical correlations. Ann Rheum Dis 1989; 48: 594–599
  • Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1979; 227: 680–685
  • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer to proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350–5354
  • Tan E M. ILAR/IUIS international ANA committee: Reference reagents for antinuclear antibodies. Arthritis Rheum 1988; 31: 1331
  • Field M, Williams D G, Charles P, Maini R W. Specificity of anti-Sm antibodies by ELISA for systemic lupus erythematosus: increased sensitivity of detection using purified peptide antigens. Ann Rheum Dis 1988; 47: 820–825
  • Maddison P J, Skinner R P, Vlachoyiannopoulos P, Brennand D M, Hough D. Antibodies to RNP, Sm, Ro (SS-A) and La (SS-B) detected by ELISA: their specificity and inter-relations in connective tissue disease sera. Clin Exp Immunol 1985; 62: 337–345
  • Westgeest A AA, Van Den Brink H G, De Jong J, Swaak A JG, Smeenk R JJ. Antinuclear antibodies in patients with systemic lupus erythematosus: a comparison of counterimmunoelectrophoresis and immunoblotting. Rheumatol Int 1987; 7: 77–82
  • Beaufils M, Kouki F, Mignon F, Camus J P, Morel Maroger L, Richet G. Clinical significance of anti-Sm antibodies in systemic lupus erythematosus. Amer J Med 1983; 74: 201–205
  • Munves E F, Schur P H. Antibodies to Sm and RNP. Prognostication of disease involvement. Arthritis Rheum 1983; 26: 848–853
  • Winn D M, Wolfe J F, Lindberg D A, Fristoe F H, Kingsland L, Sharp G C. Identification of a clinical subset of systemic lupus erythematosus by antibodies to the Sm antigen. Arthritis Rheum 1979; 22: 1334–1334

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.